Biomarkers in Environmental and Human Health Biomonitoring

An Integrated Perspective

1st Edition - May 29, 2024
Editors: Ritu Mishra, Sughosh Madhav, Rahul Kumar Dhaka, Parveen Garg
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 3 8 6 0 - 7
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 3 8 6 1 - 4

Biomarkers in Environmental and Human Health Biomonitoring: An Integrated Perspective provides a holistic view of the biomonitoring of environmental degradation, accumulat… Read more

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Biomarkers in Environmental and Human Health Biomonitoring: An Integrated Perspective provides a holistic view of the biomonitoring of environmental degradation, accumulated toxicity, and associated human health concerns. The book incorporates theoretical and practical aspects of the biomonitoring of environmental pollution and the health surveillance of ecological communities using samples from living organisms which are analyzed for contaminants and toxin levels. In the first half, the book provides a general overview if the different types of biomarkers, their significance as bioindicators for contaminants and detection of toxicity, as well as how they can be utilized in the restoration of degraded ecosystems.

The second half of the book discusses molecular biomarkers and how they are used as diagnostic and prognostic tools for pollution monitoring. It also reviews analytical tools used to validate the biomarkers in the detection and monitoring of pollution and disease. Finally, the book delves into how novel approaches like genetic ecotoxicology; Big Data, and artificial intelligence calculates the potential consequences of environmental pollution on the ecosystems and on human health.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Preface
Chapter 1. Biomarkers for the detection of water pollution in rivers
Abstract
1.1 Introduction
1.2 Biomarkers for monitoring pollution in riverine ecosystem
1.3 Conclusions
1.4 Further prospects
Acknowledgments
References
Chapter 2. Biomarkers to assess the water pollution in lakes and rivers
Abstract
2.1 Introduction
2.2 Impacts of water pollutants on aquatic ecosystems
2.3 Conventional methods of ecotoxicity assessments
2.4 Biomarkers as bioindicators for water contaminant analysis
2.5 Future direction
2.6 Conclusion
References
Chapter 3. Native crustaceans—a biomonitoring tool for ecological risk assessment
Abstract
3.1 Introduction
3.2 Crustaceans as bioindicators in freshwater
3.3 Crustaceans as bioindicators in marine water
3.4 Methods for establishing crustaceans as bioindicators
3.5 Significance of bioindicators
3.6 Concluding remarks
References
Chapter 4. Fish biomarkers in environmental biomonitoring: an insight into water pollution
Abstract
4.1 Introduction
4.2 Biomonitoring
4.3 Biomarkers
4.4 Conclusion
References
Chapter 5. Fish blood serum as a biomarker of water pollution
Abstract
5.1 Introduction
5.2 Biomarkers
5.3 Development of biomarker
5.4 Types of serum biomarkers
5.5 Enzymatic biomarkers
5.6 Hematology and immunology biomarkers
5.7 Biomarkers of hormones
5.8 Biomarkers of endocrine disruption
5.9 Histopathology biomarkers
5.10 Fish biomarkers and environmental danger valuation
5.11 Biotransformation enzymes
5.12 Parameters of oxidative stress
5.13 Superoxide dismutase superoxide dismutase
5.14 Catalase
5.15 Glutathione reductase
5.16 Biotransformation products
5.17 Bile’s polycyclic aromatic hydrocarbon metabolites
5.18 Multixenobiotic resistance, stress proteins, and metallothioneins
5.19 (Heat-shock proteins) Stress proteins
5.20 Metallothioneins
5.21 Multixenobiotic resistance
5.22 Other hematological variables
5.23 Immunological characteristics
5.24 Conclusion
References
Chapter 6. Microplastics—a major threat to marine environment and applicability of biomarkers
Abstract
6.1 Introduction
6.2 Microplastic and cocontaminants
6.3 Microplastic exposure pathways
6.4 Microplastics impact on marine organisms
6.5 Physical impacts
6.6 Chemical impacts
6.7 Biological impacts
6.8 Biomarkers of plastic pollution in marine habitats
6.9 Oxidative stress
6.10 Geno and neurotoxicity
6.11 Metabolic disturbance
6.12 Conclusion
References
Chapter 7. Microbial biomarkers for detection of environmental pollution
Abstract
7.1 Introduction
7.2 Microbial biomarkers for pollution detection
7.3 Effect of pollutants on the microbial community
7.4 Indicator species for pollution detection and application of biomarkers
7.5 Conclusion
References
Chapter 8. Microbial biomarkers–based sensors for detection of environmental pollution
Abstract
8.1 Introduction
8.2 Environmental pollution and its associated biomarkers
8.3 Biomarkers
8.4 Contaminated water biomarkers
8.5 Contaminated soil biomarkers
8.6 Contaminated air biomarkers
8.7 Biosensors
8.8 Microbial biosensors
8.9 Electrochemical biosensors
8.10 Optical biosensors
8.11 The market value of biosensors
8.12 Advantages and disadvantages of microbial biosensors
8.13 Conclusion and future perspectives
References
Chapter 9. Plants as biomarkers for monitoring environmental pollution
Abstract
9.1 Introduction
9.2 Plants as biomarkers for monitoring heavy-metal contamination
9.3 Plant indicators of environmental pollution and environmental monitoring
9.4 Biomarkers of plants with different types of ecological strategies
9.5 Stress biomarkers for different types of abiotic stress strategies
9.6 Conclusion and future prospects
References
Chapter 10. Plant biomarkers for environmental monitoring
Abstract
10.1 Introduction
10.2 Types of biomarkers for environmental monitoring
10.3 Plants as biomarkers for environmental pollution monitoring
10.4 Conclusion
References
Further reading
Chapter 11. Omics tools in understanding environment-induced stresses in plants
Abstract
11.1 Introduction
11.2 Omics tools for stress identification in plants
11.3 Biomarker-based tools to assess abiotic stress in plants
11.4 Molecular markers for the disease identification in plants
11.5 Recommendations and future research pathways
11.6 Conclusion
Acknowledgments
References
Chapter 12. The impact of climate change on polar ichthyofauna biodiversity
Abstract
12.1 Introduction
12.2 Environmental condition in the Arctic and Antarctic Ocean
12.3 Antifreeze glycoproteins
12.4 The origin and convergence of antifreeze glycoproteins in Arctic cod and Antarctic notothenioid
12.5 Adaptation in the expression of hemoglobin and myoglobin genes in Arctic and Antarctic ichthyofauna
12.6 Impact of temperature on the Arctic and Antarctic ichthyofaunas
12.7 Thermal restrictions and adaptations of Arctic cod and Antarctic notothenioid
12.8 Conclusion
Conflict of interest
References
Chapter 13. Biomarkers for the biodiversity loss and restoration of degraded ecosystems
Abstract
13.1 Introduction
13.2 Environmental biomonitoring
13.3 Types of biomarkers
13.4 Biomarkers in the field of aquatic and terrestrial ecosystems
13.5 Application of biomarkers in conservation and the restoration of degraded ecosystems
13.6 Recent trends of utilizing biomarkers in the assessment of degraded ecosystems
13.7 Challenges
13.8 Conclusion
13.9 Future prospects
References
Chapter 14. Nanoparticle induced plant stress: unraveling biomarkers for enhanced detection and mitigation
Abstract
14.1 Introduction
14.2 Plant stress and its significance
14.3 Nanoparticles in plant stress
14.4 Uptake and translocation of nanoparticles in plants
14.5 Biomarkers for assessing plant stress
14.6 Challenges and future directions
14.7 Conclusions
Acknowledgment
References
Chapter 15. Biomarkers for disease identification
Abstract
15.1 Introduction
15.2 Technologies for the discovery of biomarkers
15.3 Synthesis of microRNA
15.4 Constraints of circulating microRNA as biomarkers
15.5 Conclusion
References
Chapter 16. Biomarkers for disease identification and drug development
Abstract
16.1 Introduction
16.2 Types of biomarkers
16.3 Biomarker description
16.4 Clinical outcome assessments and clinical endpoints
16.5 Surrogate endpoints
16.6 Biomarkers in drug development
16.7 Biomarkers in disease identification
16.8 Upcoming biomarkers
16.9 Conclusion
16.10 Future perspective and challenges
References
Chapter 17. Biomarkers for toxicity detection
Abstract
17.1 Introduction
17.2 Types of biomarkers
17.3 Biomarkers in toxicity testing
17.4 Detectable biomarkers
17.5 Biomarkers related to drug-induced toxicity
17.6 Importance of understanding specific mechanisms of toxicity in drug development
17.7 Conclusion
Acknowledgment
Conflicts of interest
References
Chapter 18. Integrated biomarker responses: Unveiling insights through serum biochemistry, oxidative stress, genotoxicity and histopathology
Abstract
18.1 Introduction
18.2 What are biomarkers?
18.3 Approaches to biological monitoring
18.4 Summary
References
Chapter 19. HLA-B27: establishing association with autoimmune disorders
Abstract
19.1 Introduction
19.2 Structure of HLA-B27
19.3 Role of HLA-B27 in disease pathogenesis
19.4 Role of HLA-B27 in prevalence of autoimmune diseases
19.5 Geographical distribution and prevalence of HLA-B27 and its subtypes
19.6 HLA-B27 typing
19.7 Concluding remarks
References
Chapter 20. Can human leukocyte antigen alleles be predictive biomarker for rheumatic heart disease?
Abstract
20.1 Introduction
20.2 Genetic predisposition in rheumatic fever/rheumatic heart disease
20.3 Impact of social and environmental factors
20.4 Conclusion
References
Index

Ritu Mishra

Dr. Ritu Mishra is currently an Assistant Professor at Department of Botany, University of Allahabad, Prayagraj, India. She obtained her PhD in Molecular Virology and Neuropathogenesis from the Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. She pursued her postdoctoral studies at Max Plank Institute of Molecular Biomedicine, Muenster, Germany. Her research investigates the molecular mechanisms of vascular pathologies during viral infection and metastasis. She has published multiple research papers, review papers, and chapters on viral neuropathogenesis and soil microbial contamination

Affiliations and expertise

Assistant Professor at Department of Botany, University of Allahabad, Prayagraj, India

Sughosh Madhav

Dr. Sughosh Madhav is a Postdoctoral Fellow at the Department of Civil Engineering, Jamia Millia Islamia, New Delhi, India. He has obtained his master’s degree from the Department of Environmental Science Banaras Hindu University, Varanasi, India. He earned his doctorate from Jawaharlal Nehru University, New Delhi, India. He has published various research papers, authored book chapters in environmental geochemistry, water pollution, and wastewater, and edited many books related to water resource management with Elsevier, Springer, and Wiley

Affiliations and expertise

Postdoctoral Fellow, Department of Civil Engineering, Jamia Millia Islamia, New Delhi, India

Rahul Kumar Dhaka

Dr. Rahul Kumar Dhaka is currently an Assistant Professor at Department of Chemistry, College of Basic Sciences and Humanities at Chaudhary Charan Singh Haryana Agricultural University (CCS HAU), Hisar, Haryana, India. He previously worked as an Assistant Professor in Hanyang University, Seoul, South Korea. Dr. Rahul earned his PhD in Physical and Analytical Chemistry from prestigious IIT Roorkee, India and has more than 10 years of professional research experience in material science, environmental and analytical chemistry. He has contributed numerous book chapters and published more than 40 research/review papers in international journals of repute such as high impact journals like Chemical Reviews, Coordination Chemistry Reviews Factor, and Chemical Engineering Journal.

Affiliations and expertise

Assistant Professor, Chaudhary Charan Singh Haryana Agricultural University (CCS HAU), Department of Chemistry, College of Basic Sciences & Humanities, Hisar, Haryana, India

Parveen Garg

Professor Parveen Garg is currently a Principal and Professor at Swami Shradhanand College, New Delhi, India. He obtained his master’sfrom Pant Nagar Agricultural University, Pant Nagar, Uttarakhand, India. He was awarded a doctorate from Jawaharlal Nehru University, New Delhi, India. He is an expert of biodiversity conservation and stress in plants due to environmental pollution. Professor Garg has published more than 20 research papers, is a regular reviewer of various international journals, and has edited three books on the environment and sustainable development.

Affiliations and expertise

Principal and Professor, Swami Shradhanand College, University of Delhi, New Delhi, India

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Biomarkers in Environmental and Human Health Biomonitoring

An Integrated Perspective

Purchase options

Institutional subscription on ScienceDirect

Ritu Mishra

Sughosh Madhav

Rahul Kumar Dhaka

Parveen Garg