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Elsevier

Biomarkers in Cancer Detection and Monitoring of Therapeutics

Volume 1: Discovery and Technologies

  • 1st Edition - November 16, 2023
  • Latest edition
  • Editors: Ranbir Chander Sobti, Awtar Krishan, Aastha Sobti
  • Language: English

Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predis… Read more

Description

Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.

Key features

  • Provides up-to-date information on current molecular biomarkers research for cancer
  • Presents basic research aspects and novel technologies applied in the discovery of new biomarkers
  • Discusses several technologies, including artificial intelligence, robotics, data mining, gene editing, omics and their applicability for specific cancer types

Readership

Researchers and graduate students on cancer research, oncologists, Clinical researchers

Table of contents

1. CANCER BURDEN: EPIDEMIOLOGY, RACIAL AND GEOGRAPHICAL DISPARITIES
Shaveta Menon and Ramila Bisht

2. MILESTONES IN CANCER RESEARCH
Siddharth Sharma

3. TECHNOLOGICAL EVOLUTION IN CANCER DIAGNOSISAND THERAPEUTICS
Sudeep Bose I

4. HOW DOES TIME SPEAK ABOUT CANCER, ITS DIAGNOSIS, TREATMENTS AND CHALLENGES?
Asit Ranjan Ghosh

5. ROLE OF ARTIFICIAL INTELLIGENCE IN CANCER DIAGNOSTICS AND THERAPEUTICS
B. Medhi

6. ADDRESSING THE DIAGNOSIS AND THERAPEUTICS OF MALIGNANT TUMOUR CELLS
Anjoy Mahji

7. SOMATIC MUTATION: PHARMACOGENOMICS IN ONCOLOGY CARE
Shamsher Singh

8. INSIGHTS INTO GENETIC PREDISPOSITION OF SOMATIC CANCERS
B. Medhi

9. THE USE OF TUMOR MARKERS IN PROGNOSIS OF CANCER AND STRATEGIES TO PREVENT CANCER PREDISPOSITION AND PROGRESS
Osama Ahmed, Mohamed Abd-Elbaset, Noha Ahmed and Eman Abd Elhaliem

10. CYTOGENETICS TO MULTI-OMICS IN BIOLOGY OF CANCER
Sikander S. Gill

11. ROLE OF NON-CODING RNA AS BIOMARKERS FOR CANCER
Bikash Medhi and B. Medhi

12. VIRAL miRNA's: DIAGNOSTIC AND PROGNOSTIC BIOMARKERS FOR CANCER AND INFECTIOUS DISEASE
Sunil Babu Gosipatala, Dr. Abhishek Pandeya, Raj Kumar Khalko, Ranbir C. Sobti Sr., Sneha Kumari, Prashansa Khanna and Utkarsha Vishwakarma

13. PHARMACOGENOMICS AND ONCOLOGY: A THERAPEUTIC APPROACH FOR CANCER TREATMENT
Shamsher Singh and Anil Kumar

14. ENVIRONMENTAL FACTORS INFLUENCING EPIGENETIC CHANGES INITIATING NEOPLASTIC CHANGES
B. Medhi

15. OBESITY: EMERGING RISK FACTOR FOR CANCER BEYOND METABOLIC SYNDROME
Ranbir C. Sobti Sr.

16. HOMOLOGOUS REPAIR DEFICIENCY AND PARP INHIBITORS IN CANCER MANAGEMENT
Shivani Arora Mittal

17. MOLECULAR PROSPECTS OF TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES (TALENS) IN CANCER
Mani Chopra

18. IMMUNO PEPTIDOMIC APPROACHES FORMANAGEMENT OFCANCER
B. Medhi

19. REGULATION OF TUMOR MICROENVIRONMENT BY NUTRIENT TRAFFICKING
B. Medhi

20. PRECISION MEDICINE : DOSE FOR ANTI CANCER THERAPY
Dr Shiva Tushir

Product details

  • Edition: 1
  • Latest edition
  • Published: November 16, 2023
  • Language: English

About the editors

Ranbir Chander Sobti

Editor

Dr. Ranbir Chander Sobti is Emeritus Professor at Punjab University, Chandigarh, and Honorary Scientist at the Indian National Science Academy. He started his career as a cytogeneticist and progressed to molecular biology and disease processes of cancer, COPD, AIDS, metabolic syndrome, and kidney diseases. His research spans genomic instability, epigenetic alterations, and cancer predisposition across multiple tumour types. He is a Fellow of the Third World Academy of Sciences, National Academy of Sciences India, Indian National Science Academy, National Academy of Medical Sciences, National Academy of Agricultural Sciences, Canadian Academy of Cardiovascular Diseases Royal Society of biology and international Association of Cancer Research. Dr. Sobti has participated in several book projects, including Elsevier’s Advances in Animal Experimentation and Modeling; Biomarkers in Cancer Detection and Monitoring of Therapeutics; Molecular Medicine and Biomedical Research in the Era of Precision Medicine; One Planet, One Health, One Future; Probiotics; and Public and Environmental Health.

Affiliations and expertise
Professor (Emeritus), Department of Biotechnology, Panjab University, Chandigarh, India

Awtar Krishan

Editor

Dr. Awtar Krishan is Emeritus Professor of Pathology at the University of Miami Miller School of Medicine, USA. Before joining the University of Miami, he served at the Sidney Farber Cancer Institute, now part of Dana-Farber Cancer Institute, as Head of the Tissue Ultrastructure and Experimental Pathology Labs, and at Miami, he served as Scientific Director of the Comprehensive Cancer Center. His research has focused on cytogenetics, analytical cytology, flow cytometry, cancer biology, and experimental therapeutics. He is recognized for developing and advancing flow-cytometric methods for measuring cellular DNA content, drug retention and resistance, hormone receptors, and tumor-cell markers. He has published extensively and has contributed internationally to cytometry education through workshops and professional societies.

Affiliations and expertise
Emeritus Professor of Pathology, University of Miami Miller School of Medicine, USA

Aastha Sobti

Editor
Dr Aastha Sobti is a Postdoctoral Research Fellow at the UPMC Hillman Cancer Center, University of Pittsburgh, where she works within the Mowery Laboratory on HPV-associated head and neck cancer. Her research focuses on the tumour immune microenvironment of HPV-positive head and neck squamous cell carcinoma and laryngeal papillomatosis, using spatial transcriptomics, single-cell RNA sequencing, and computational multi-omics. She previously worked as a Machine Learning Scientist at Alligator Bioscience in Sweden. She has co-edited volumes for Elsevier, including Biomarkers in Cancer Detection and Monitoring of Therapeutics (2023), Molecular Medicine and Biomedical Research in the Era of Precision Medicine (2025), and Advanced Technologies for Disease Intervention (2026).
Affiliations and expertise
Postdoctoral Research Fellow, UPMC Hillman Cancer Center, University of Pittsburgh, USA

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