Bioinformatics
Methods and Applications
- 1st Edition - October 21, 2021
- Latest edition
- Editors: Dev Bukhsh Singh, Rajesh Kumar Pathak
- Language: English
Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life scienc… Read more
Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities.
- Covers basic and more advanced developments of bioinformatics with a diverse and interdisciplinary approach to fulfill the needs of readers from different backgrounds
- Explains in a practical way how to decode complex biological problems using computational approaches and resources
- Brings case studies, real-world examples and several protocols to guide the readers with a problem-solving approach
Graduate students of bioinformatics; biomedical researchers in general
1. Introduction to Basics of Bioinformatics 2. Biological Databases and their Applications 3. Biological Sequence Analysis 4. Genome Assembly and Annotation 5. Computational Molecular Phylogeny: Concepts and Applications 6. Applications and challenges of microarray and RNA-sequencing 7. RNAseq Data Analysis 8. Analysis of SSR and SNP Markers 9. Gene Ontology (GO): Application and Importance in Functional Annotation of the Genomic Data 10. Metagenomics: The Boon for Microbial World Knowledge and Current Challenges 11. Protein structure Prediction 12. Structural and Functional analysis of protein 13. Computational Approaches in Drug designing 14. Structure-Based Drug Designing 15. Ligand-Based Drug Designing 16. Discovery and Optimization of Lead Molecules in Drug Designing 17. Pharmacophore modeling and its applications 18. Molecular Docking and Molecular Dynamics Simulation 19. Pharmacokinetics and Pharmacodynamics analysis of Drug Candidates 20. Computational Approaches for Vaccine Designing 21. Metabolomics and Flux Balance Analysis 22. Topological Parameters, Patterns, and Motifs in Biological Networks 23. Network Biology and its Application 24. Pathway Modeling and Simulation Analysis 25. Systems Biology and Big Data Analytics 26. Machine Leaning in Bioinformatics 27. Bioinformatics and Biological Data mining
- Edition: 1
- Latest edition
- Published: October 21, 2021
- Language: English
DS
Dev Bukhsh Singh
Dr. Dev Bukhsh Singh is currently an Assistant Professor in the Department of Biotechnology at Siddharth University, Kapilvastu, Siddharth Nagar, India since 2021. He also served as Assistant Professor in the Department of Biotechnology at Chhatrapati Shahu Ji Maharaj University, Kanpur, India from 2009-2021. He received BSc (Biology) and MSc from the University of Allahabad, an MTech from the Indian Institute of Information Technology, Prayagraj India, and a PhD in Biotechnology from Gautam Buddha University, India. He has been actively involved in teaching BSc and MSc Biotechnology students since 2009. His areas of research are medicinal biology, lead compound search, and drug design. He published three edited books: Frontiers in Protein Structure, Function, and Dynamics Computer-Aided Drug Design and Bioinformatics: Methods and Applications. He is a member of various national and international academic bodies and is a reviewer for several international journals.
Affiliations and expertise
Department of Biotechnology, Siddharth University, Siddharth Nagar, IndiaRP
Rajesh Kumar Pathak
Rajesh Kumar Pathak completed his BSc from Barkatullah University, Bhopal, MSc from Chhatrapati Shahu Ji Maharaj University, Kanpur, and PhD from Uttarakhand Technical University, Dehradun, India. He has authored several articles in international journals including, Scientific Reports, Computational Biology and Chemistry, OMICS: A Journal of Integrative Biology, Frontiers in Plant Science, 3 Biotech, Journal of Biomolecular Structure and Dynamics, etc. His research interests lie in the areas of the genome and transcriptome assembly and annotation, microarray data analysis, pathway modeling, and network analysis, molecular docking, virtual screening, and molecular dynamics simulation. He has worked as a Teaching Personnel at G. B. Pant University of Agriculture & Technology, Pantnagar, India, and Teaching Assistant at the School of Agricultural Biotechnology, Punjab Agricultural University, Ludhiana, India.
Affiliations and expertise
Post-Doctoral Researcher at Chung-Ang University, Anseong, Gyeonggi-do, Republic of KoreaRead Bioinformatics on ScienceDirect