Bioinformatics
Methods and Applications
- 1st Edition - October 21, 2021
- Latest edition
- Editors: Dev Bukhsh Singh, Rajesh Kumar Pathak
- Language: English
Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life scienc… Read more
Description
Description
Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities.
Key features
Key features
- Covers basic and more advanced developments of bioinformatics with a diverse and interdisciplinary approach to fulfill the needs of readers from different backgrounds
- Explains in a practical way how to decode complex biological problems using computational approaches and resources
- Brings case studies, real-world examples and several protocols to guide the readers with a problem-solving approach
Readership
Readership
Graduate students of bioinformatics; biomedical researchers in general
Table of contents
Table of contents
1. Introduction to Basics of Bioinformatics 2. Biological Databases and their Applications 3. Biological Sequence Analysis 4. Genome Assembly and Annotation 5. Computational Molecular Phylogeny: Concepts and Applications 6. Applications and challenges of microarray and RNA-sequencing 7. RNAseq Data Analysis 8. Analysis of SSR and SNP Markers 9. Gene Ontology (GO): Application and Importance in Functional Annotation of the Genomic Data 10. Metagenomics: The Boon for Microbial World Knowledge and Current Challenges 11. Protein structure Prediction 12. Structural and Functional analysis of protein 13. Computational Approaches in Drug designing 14. Structure-Based Drug Designing 15. Ligand-Based Drug Designing 16. Discovery and Optimization of Lead Molecules in Drug Designing 17. Pharmacophore modeling and its applications 18. Molecular Docking and Molecular Dynamics Simulation 19. Pharmacokinetics and Pharmacodynamics analysis of Drug Candidates 20. Computational Approaches for Vaccine Designing 21. Metabolomics and Flux Balance Analysis 22. Topological Parameters, Patterns, and Motifs in Biological Networks 23. Network Biology and its Application 24. Pathway Modeling and Simulation Analysis 25. Systems Biology and Big Data Analytics 26. Machine Leaning in Bioinformatics 27. Bioinformatics and Biological Data mining
Product details
Product details
- Edition: 1
- Latest edition
- Published: October 21, 2021
- Language: English
About the editors
About the editors
Dev Bukhsh Singh
Editor
Dr. Dev Bukhsh Singh is Assistant Professor in the Department of Biotechnology at Siddharth University, Kapilvastu, India, a position he has held since 2021. Previously, he served as Assistant Professor in the Department of Biotechnology at Chhatrapati Shahu Ji Maharaj University, Kanpur, India, from 2009 to 2021. His research focuses on medicinal biology, lead compound discovery, and drug design. He has been involved in teaching and mentoring undergraduate and postgraduate students in biotechnology since 2009. Dr. Singh has edited books in the areas of protein structure and function, computer-aided drug design, Protein-based therapeutics, medicinal biotechnology, genomics, and bioinformatics. He is a member of professional academic organizations and serves as a reviewer for scholarly journals. His academic interests include applying computational and biotechnological approaches to drug discovery and related life science research.
Affiliations and expertise
Siddharth University, Siddharth Nagar, IndiaRajesh Kumar Pathak
Editor
Rajesh Kumar Pathak completed his BSc from Barkatullah University, Bhopal, MSc from Chhatrapati Shahu Ji Maharaj University, Kanpur, and PhD from Uttarakhand Technical University, Dehradun, India. He has authored several articles in international journals including, Scientific Reports, Computational Biology and Chemistry, OMICS: A Journal of Integrative Biology, Frontiers in Plant Science, 3 Biotech, Journal of Biomolecular Structure and Dynamics, etc. His research interests lie in the areas of the genome and transcriptome assembly and annotation, microarray data analysis, pathway modeling, and network analysis, molecular docking, virtual screening, and molecular dynamics simulation. He has worked as a Teaching Personnel at G. B. Pant University of Agriculture & Technology, Pantnagar, India, and Teaching Assistant at the School of Agricultural Biotechnology, Punjab Agricultural University, Ludhiana, India.
Affiliations and expertise
Post-Doctoral Researcher at Chung-Ang University, Anseong, Gyeonggi-do, Republic of KoreaView book on ScienceDirect
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