Basic Principles in Nucleic Acid Chemistry V1
- 1st Edition - January 1, 1974
- Editor: Paul O.P. Ts'o
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 7 0 1 9 0 1 - 7
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 1 2 4 8 5 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 4 4 0 0 - 1
Basic Principles in Nucleic Acid Chemistry, Volume I provides information pertinent to the fundamental aspects of nucleic acids. This book discusses the development of the basic… Read more

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Request a sales quoteBasic Principles in Nucleic Acid Chemistry, Volume I provides information pertinent to the fundamental aspects of nucleic acids. This book discusses the development of the basic principles in nucleic acid research that will serve as a foundation for further advancement in nucleic acid research. Organized into six chapters, this volume begins with an overview of the history of the scientific study of nucleic acid as a genetic material. This text then examines the utility of the analogs of the naturally occurring nucleic acid components as biochemical tools and as therapeutic agents. Other chapters consider mass spectrometry that deals with the production and chemistry of ions in the vapor phase. This book discusses as well the various aspects of the excited states of the nucleic acids. The final chapter deals with the systematic study of the physiochemical properties of the monomeric units of nucleic acid. This book is a valuable resource for molecular biologists, scientists, and research workers.
List of Contributors
Preface
Contents of Other Volumes
1. In the Beginning
I. The Beginning of the Scientific Investigation of Nucleic Acid
II. The Beginning of the Formation of Nucleic Acid as Genetic Material and its Progressive Change Reflected in the Evolution of the Biological Kingdom
III. The Beginning of the Influence of Nucleic Acid Research on the Future of Man—"Intelligent" Evolution
References
2. Chemical Syntheses and Transformations of Nucleosides
I. Introduction
II. Synthesis of Nucleosides
III. Chemical Transformation of the Sugar Moieties of Nucleosides
IV. Chemical Transformations of the Heterocyclic Base Moieties of Nucleosides
V. Chemical Transformations That Involve both the Sugar and the Heterocyclic Base
3. Mass Spectrometry
I. Introduction
II. Production of Mass Spectra
III. Mass Spectra of Purine and Pyrimidine Bases
IV. Nucleosides and their Derivatives
V. Applications of Mass Spectrometry to Nucleotides
VI. Experimental Note
References
4. Excited States of Nucleic Acids
I. Introduction
II. Summary of Molecular Electronic Excited States
III. Excited States of Nucleotides
IV. Luminescence of Nucleotides as a Probe: The Y Base in tRNA
V. Interacting Chromophores
VI. Excited Polynucleotides
VII. Excited State Precursors for Photoproducts
References
5. Infrared and Raman Spectroscopy
I. Introduction
II. Vibrations in Nucleic Acids
III. Infrared Spectra of Nucleic Acids
IV. Raman Spectra of Nucleic Acids
References
6. Bases, Nucleosides, and Nucleotides
I. Structure, Configuration, Conformation, and Other Intrinsic Properties
II. Interaction of the Monomers
References
Author Index
Subject Index
- No. of pages: 648
- Language: English
- Edition: 1
- Published: January 1, 1974
- Imprint: Academic Press
- Hardback ISBN: 9780127019017
- Paperback ISBN: 9780124124851
- eBook ISBN: 9780323144001
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