Antioxidant and Redox Regulation of Genes
- 1st Edition - November 8, 1999
- Latest edition
- Editors: Chandan K. Sen, Lester Packer, Patrick A. Baeuerle
- Language: English
This volume addresses oxidant-reduction or redox and antioxidant sensitive molecular mechanisms and how they are implicated in different disease processes. Possible strategies to… Read more
- Reactive species as intracellular messengers
- Redox regulation of cellular responses
- Clinical implications of redox signaling and antioxidant therapy
L.-O. Klotz, K. Briviba, and H. Sies, Signalling by Singlet Oxygen in Biological Systems.
D.R. Crawford, T. Suzuki, and K.J.A. Davies, Oxidant-modulated Gene Expression.
H.H. Hassanain and P.J. Goldschmidt-Clermont, RAC, Superoxide, and Signal Transduction.
S.K. Koliwad, A.K. Brzezinska, and S.J. Elliott, Redox Regulation of Ion Channels.
J. Giron-Calle and H.J. Forman, Cell Ca2+ in Signal Transduction: Modulation in Oxidative Stress.
G.L. Schieven, Introduction of Protein Tyrosine Phosphorylation by Oxidative Stress and its Implications.
A.A. Deora and H.M. Lander, Regulation of Signal Transduction and Gene Expression by Reactive Nitrogen Species.
Redox Sensitive Molecular Processes and Cellular Responses:
P.A. Baeuerle, Reactive Oxygen Species as Costimulatory Signals of Cytokine-Induced NFkappaB Activation Pathways.
T. Okamoto, T. Tetsuka, and T. Kawabe, Redox Regulation of Nuclear Factor kappa B.
C.K. Sen, Oxidants and Antioxidants in Aptosis: Role of Bcl-2.
V. Goossens, K. De Vos, D. Vercammen, M. Steemans, K. Vancompernolle, W. Fiers, P. Vandenabeele, and J. Grooten, Role of Reactive Oxygen Species in TNF Toxicity.
S. Roy, C.K. Sen, A. Gozin, V. Andrieu, and C. Pasquier, Redox Regulation of Cell Adhesion Processes.
H. Masutani, M. Ueno, S. Ueda, and J. Yodoi, Role of Thioredoxin and Redox Regulation in Oxidative Stress Response and Signalling.
A.H. Schönthal, S. Mueller, and E. Cadenas, Redox Regulation of p21, Role of Reactive Oxygen and Nitrogen Species in Cell Cycle Progression.
Clinical Implications of Redox Signaling and Antioxidant Therapy:
H. Viita and S. Ylä-Hertuala, Effect of Lipoxygenases on Gene Expression in Mammalian Cells.
A. Azzi, Tocopherol in the Pathogenesis of Atherosclerosis: One Molecule, Several Functions.
D.-Y. Jin and K.-T. Jeang, Peroxiredoxins in Cell Signaling and HIV Infection.
J.S. Bertram, T. King, L. Fukishima, and F. Khachik, Enhanced Activity of an Oxidation Product of Lycopene Found in Tomato Products and Human Serum Relevant to Cancer Prevention.
C. Bladier, J.B. de Haan, and I. Kola, Antioxidant Genes and Reactive Oxygen Species in Down's Syndrome.
B.S. Kristal and B.P. Yu, Oxidant-mediated Repression of mtDNA Transcription.
Y. Kajimoto, Y. Yamasaki, T. Matsuoka, H. Kaneto, and M. Hori, Suppression of the Insulin Gene Promoter Activity by Oxidative Stress.
N. Maulik and D.K. Das, Redox Regulation of Ischemic Adaptation.
W.C. Orr and R.S. Sohal, Oxidative Stress as a Governing Factor in Physiological Aging.
W. Dröge, V. Hack, R. Breitkreutz, E. Holm, S. Holm, and R. Kinscherf, Antioxidants in Senescence and Wasting.
Subject Index.
- Edition: 1
- Latest edition
- Published: November 8, 1999
- Language: English
CS
Chandan K. Sen
LP
Lester Packer
Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de l’Ordre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California.
He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology:
Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the “Antioxidant Network” regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cell’s redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America.
PB