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This new volume of Current Topics in Developmental Biology covers recent progresses in our understanding of animal metamorphosis. Over a dozen of leading experts reviews studies r… Read more
ROBOTICS & AUTOMATION
Up to 25% off Essentials Robotics and Automation titles
This new volume of Current Topics in Developmental Biology covers recent progresses in our understanding of animal metamorphosis. Over a dozen of leading experts reviews studies ranging from morphological, molecular to genetic analyses of metamorphosis in a broad spectrum of animals, including insects, fish. Topics include molecular evolution in metamorphosis, the synthesis and function of hormones in regulating metamorphic timing and rate, regulation and function of nuclear hormone receptors, neuroendocrine control of metamorphosis, tissue specific metamorphic events such as autophagy and stem cell development, and applications of genome-wide analysis technologies for studying metamorphosis.
Series Page
Contributors
Preface
Chapter One. Developmental Checkpoints and Feedback Circuits Time Insect Maturation
1 Introduction
2 Checkpoint Controls for Progression of Development
3 Signals Converging on the PG
4 Shaping Discrete Ecdysone Pulses
5 Summary and Perspectives
References
Chapter Two. What Goes Up Must Come Down
1 Introduction
2 Historical Perspective
3 The Ecdysone Hierarchy I: Hormone Action at the Onset of Metamorphosis
4 The Ecdysone Hierarchy II: Early Response Genes
5 The Ecdysone Hierarchy III: Early-Late Response Genes and βftz-f1
6 Upstream of the Hormone: Ecdysone Synthesis in the Prothoracic Glands
7 Role Reversal: The Ecdysone Hierarchy Regulates Its Own Hormone
8 broad Controls a Key Component of Cellular Cholesterol Transport
9 DHR4 is a Key Mediator of PTTH Signaling
10 DHR3/E75-Mediated NO Signaling Is a Critical Player of Ecdysteroidogenesis
11 Other Transcription Factors with Known Expression in the Prothoracic Gland
References
Chapter Three. Hormonal Regulation of Insect Metamorphosis with Special Reference to Juvenile Hormone Biosynthesis
1 Introduction
2 Regulation of JH Biosynthesis
3 Molecular Action of JH on Insect Molting and Metamorphosis
4 Conclusion
References
Note Added in Proof
Chapter Four. The Role of Autophagy in Drosophila Metamorphosis
1 Introduction
2 Autophagy
3 Drosophila as a Model for Studying the Interface Between Steroid Signaling, Nutrition, and Growth During Development
4 Autophagy and Drosophila Development
5 Conclusions
References
Chapter Five. Metamorphosis in Teleosts
1 Introduction and Definitions
2 Metamorphic Diversity in Teleosts
3 Endocrine Controls of Teleost Metamorphosis
4 Local Mechanisms of Morphogenetic Changes
5 Conclusions
References
Glossary
Chapter Six. Flatfish
1 Introduction
2 Genetic Basis of Flatfish Asymmetry
3 Metamorphic Asymmetry of the Brain, Sensory Organs, and Behavior
4 Asymmetric Craniofacial Remodeling and the Basis of Eye Migration
5 Flatfish Evolution: A Developmental Perspective
References
Chapter Seven. Neuroendocrinology of Amphibian Metamorphosis
1 Hormonal Control of Metamorphosis
2 Neuroendocrine Control of Metamorphosis
3 Role of the Neuroendocrine System in Mediating Environmental Influences on the Timing of Metamorphosis
References
Chapter Eight. Salamander Paedomorphosis
1 What is Paedomorphosis and Why Salamanders?
2 Paedomorphosis and Salamander Life History Variation
3 Hormonal Basis of Salamander Metamorphosis
4 Hormonal Basis of Paedomorphosis
5 Paedomorphosis in the Mexican Axolotl
6 Genomic Analysis of Salamander Metamorphosis and Paedomorphosis
7 Genetic Analysis of Paedomorphosis
8 The Link Between met1 and TH Regulation of Metamorphosis
9 What Genes Map to Metamorphic Timing QTL?
10 Synthesis: Evolution of Salamander Paedomorphosis
References
Chapter Nine. Metamorphosis in a Frog That Does Not Have a Tadpole
1 Introduction
2 Loss of Tadpole Structures in Frog Direct Development
3 Thyroid Hormone Dependency in Frog Direct Development
4 Mechanisms Underlying Tadpole Deletion
5 Precocious Appearance of Frog Features in Direct Developers
6 A Possible Role for Maternal Thyroid Hormone and Thyroid Hormone Receptor
7 Questions for the Future
References
Chapter Ten. High-Throughput Sequencing Will Metamorphose the Analysis of Thyroid Hormone Receptor Function During Amphibian Development
1 Introduction
2 Xenopus tropicalis Genomic Sequence and Annotation: Current State
3 TH and TR Regulating Network Using NGS-Based Transcriptome Analysis
4 TR Interactome
5 Conclusion
References
Chapter Eleven. Establishment of Intestinal Stem Cell Niche During Amphibian Metamorphosis
1 Introduction
2 Adult Epithelial Development During Intestinal Remodeling
3 Origin of Adult Stem Cells
4 Niche Essential for Adult Stem Cell Development
5 Signaling Pathways Involved in Establishment of Stem Cell Niche
6 Evolutionary Consideration and Prospect
References
Chapter Twelve. Developmental Programs and Endocrine Disruption in Frog Metamorphosis: The Perspective from Microarray Analysis
1 Introduction
2 Developmental Programs
3 Endocrine Disruption
4 Special Topics
5 Summary and Conclusions
References
Chapter Thirteen. Is Thyroid Hormone Signaling Relevant for Vertebrate Embryogenesis?
1 Introduction
2 Both TRs and Deiodinases are Expressed During Embryogenesis
3 Both T3 and T4 are Present During Embryonic Stages
4 What Roles Does TH Signaling Have During Early Development?
5 Does TH Signaling During Early Development Represent a New Scenario for Endocrine Disruption?
6 Conclusion
References
Chapter Fourteen. Thyroid Hormones and Postembryonic Development in Amniotes
1 Introduction
2 TH Signaling: The Basics
3 TH Controls Metamorphosis in Amphibians
4 TH-Regulated Metamorphosis is an Ancestral Chordate Character
5 Mammals
6 Sauropsids
7 Conclusion
References
Index