Animal Metamorphosis

Series Page

Contributors

Preface

Chapter One. Developmental Checkpoints and Feedback Circuits Time Insect Maturation

1 Introduction

2 Checkpoint Controls for Progression of Development

3 Signals Converging on the PG

4 Shaping Discrete Ecdysone Pulses

5 Summary and Perspectives

References

Chapter Two. What Goes Up Must Come Down

1 Introduction

2 Historical Perspective

3 The Ecdysone Hierarchy I: Hormone Action at the Onset of Metamorphosis

4 The Ecdysone Hierarchy II: Early Response Genes

5 The Ecdysone Hierarchy III: Early-Late Response Genes and βftz-f1

6 Upstream of the Hormone: Ecdysone Synthesis in the Prothoracic Glands

7 Role Reversal: The Ecdysone Hierarchy Regulates Its Own Hormone

8 broad Controls a Key Component of Cellular Cholesterol Transport

9 DHR4 is a Key Mediator of PTTH Signaling

10 DHR3/E75-Mediated NO Signaling Is a Critical Player of Ecdysteroidogenesis

11 Other Transcription Factors with Known Expression in the Prothoracic Gland

References

Chapter Three. Hormonal Regulation of Insect Metamorphosis with Special Reference to Juvenile Hormone Biosynthesis

1 Introduction

2 Regulation of JH Biosynthesis

3 Molecular Action of JH on Insect Molting and Metamorphosis

4 Conclusion

References

Note Added in Proof

Chapter Four. The Role of Autophagy in Drosophila Metamorphosis

1 Introduction

2 Autophagy

3 Drosophila as a Model for Studying the Interface Between Steroid Signaling, Nutrition, and Growth During Development

4 Autophagy and Drosophila Development

5 Conclusions

References

Chapter Five. Metamorphosis in Teleosts

1 Introduction and Definitions

2 Metamorphic Diversity in Teleosts

3 Endocrine Controls of Teleost Metamorphosis

4 Local Mechanisms of Morphogenetic Changes

5 Conclusions

References

Glossary

Chapter Six. Flatfish

1 Introduction

2 Genetic Basis of Flatfish Asymmetry

3 Metamorphic Asymmetry of the Brain, Sensory Organs, and Behavior

4 Asymmetric Craniofacial Remodeling and the Basis of Eye Migration

5 Flatfish Evolution: A Developmental Perspective

References

Chapter Seven. Neuroendocrinology of Amphibian Metamorphosis

1 Hormonal Control of Metamorphosis

2 Neuroendocrine Control of Metamorphosis

3 Role of the Neuroendocrine System in Mediating Environmental Influences on the Timing of Metamorphosis

References

Chapter Eight. Salamander Paedomorphosis

1 What is Paedomorphosis and Why Salamanders?

2 Paedomorphosis and Salamander Life History Variation

3 Hormonal Basis of Salamander Metamorphosis

4 Hormonal Basis of Paedomorphosis

5 Paedomorphosis in the Mexican Axolotl

6 Genomic Analysis of Salamander Metamorphosis and Paedomorphosis

7 Genetic Analysis of Paedomorphosis

8 The Link Between met1 and TH Regulation of Metamorphosis

9 What Genes Map to Metamorphic Timing QTL?

10 Synthesis: Evolution of Salamander Paedomorphosis

References

Chapter Nine. Metamorphosis in a Frog That Does Not Have a Tadpole

1 Introduction

2 Loss of Tadpole Structures in Frog Direct Development

3 Thyroid Hormone Dependency in Frog Direct Development

4 Mechanisms Underlying Tadpole Deletion

5 Precocious Appearance of Frog Features in Direct Developers

6 A Possible Role for Maternal Thyroid Hormone and Thyroid Hormone Receptor

7 Questions for the Future

References

Chapter Ten. High-Throughput Sequencing Will Metamorphose the Analysis of Thyroid Hormone Receptor Function During Amphibian Development

1 Introduction

2 Xenopus tropicalis Genomic Sequence and Annotation: Current State

3 TH and TR Regulating Network Using NGS-Based Transcriptome Analysis

4 TR Interactome

5 Conclusion

References

Chapter Eleven. Establishment of Intestinal Stem Cell Niche During Amphibian Metamorphosis

1 Introduction

2 Adult Epithelial Development During Intestinal Remodeling

3 Origin of Adult Stem Cells

4 Niche Essential for Adult Stem Cell Development

5 Signaling Pathways Involved in Establishment of Stem Cell Niche

6 Evolutionary Consideration and Prospect

References

Chapter Twelve. Developmental Programs and Endocrine Disruption in Frog Metamorphosis: The Perspective from Microarray Analysis

1 Introduction

2 Developmental Programs

3 Endocrine Disruption

4 Special Topics

5 Summary and Conclusions

References

Chapter Thirteen. Is Thyroid Hormone Signaling Relevant for Vertebrate Embryogenesis?

1 Introduction

2 Both TRs and Deiodinases are Expressed During Embryogenesis

3 Both T3 and T4 are Present During Embryonic Stages

4 What Roles Does TH Signaling Have During Early Development?

5 Does TH Signaling During Early Development Represent a New Scenario for Endocrine Disruption?

6 Conclusion

References

Chapter Fourteen. Thyroid Hormones and Postembryonic Development in Amniotes

1 Introduction

2 TH Signaling: The Basics

3 TH Controls Metamorphosis in Amphibians

4 TH-Regulated Metamorphosis is an Ancestral Chordate Character

5 Mammals

6 Sauropsids

7 Conclusion

References

Index