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Advances in Virus Research
- 1st Edition, Volume 94 - March 10, 2016
- Editors: Margaret Kielian, Karl Maramorosch, Thomas Mettenleiter
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 4 8 2 1 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 5 2 3 7 - 2
Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.… Read more
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Request a sales quotePublished since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.
- Contain contributions from leading authorities
- Informs and updates on all the latest developments in the field of virology
Virologists, microbiologists and infectious disease specialists.
Chapter One: Functional Genomic Strategies for Elucidating Human–Virus Interactions: Will CRISPR Knockout RNAi and Haploid Cells?
- Abstract
- 1 Introduction
- 2 Host–Virus Genetic Screens
- 3 RNAi Genetic Screening Technologies and Approaches
- 4 Haploid Cell Genetic Screening Technology and Approach
- 5 CRISPR/Cas9 Genetic Screening Technologies and Approaches
- 6 Comparison of HRV-HF Screens: Arrayed MORR RNAi Versus Pooled CRISPR/Cas9
- 7 Future Directions
- Acknowledgments
Chapter Two: Alphaherpesvirus Latency: A Dynamic State of Transcription and Reactivation
- Abstract
- 1 Introduction
- 2 A Working Definition of Latency
- 3 Model Systems to Study Alphaherpesvirus Latency
- 4 Establishment of Latency
- 5 The Dynamic State of Alphaherpesvirus Latency
- 6 Conclusions and Unanswered Questions
Chapter Three: Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport
- Abstract
- 1 Introduction
- 2 The Nucleus
- 3 Herpesvirus Nuclear Egress
- 4 Nuclear Egress as a Cellular Nuclear Export Mechanism
- 5 Alternative Herpesvirus Nuclear Escape Pathways
- 6 Nuclear Egress in Other Virus Families
- 7 Summary
- Acknowledgments
Chapter Four: Structure and Associated Biological Functions of Viroids
- Abstract
- 1 Introduction
- 2 Biophysical Properties as Basis for Functional Activity
- 3 Structure of Pospiviroidae
- 4 Structure of Avsunviroidae
- 5 Structural Motifs and Their Biological Function
- 6 Perspective
- Acknowledgments
Index
- No. of pages: 198
- Language: English
- Edition: 1
- Volume: 94
- Published: March 10, 2016
- Imprint: Academic Press
- Hardback ISBN: 9780128048214
- eBook ISBN: 9780128052372
MK
Margaret Kielian
Professor Margaret Kielian works at the Department of Cell Biology, Albert Einstein College of Medicine, New York, USA.
Affiliations and expertise
Professor, Department of Cell Biology, Albert Einstein College of Medicine, NY, USAKM
Karl Maramorosch
Professor Karl Maramorosch works at Rutgers University, New Brunswick, NJ, USA.
Affiliations and expertise
Professor, Rutgers University, New Brunswick, NJ, USATM
Thomas Mettenleiter
Born: March 18, 1957 in Goeppingen, Germany
Nationality: German
1963-1967: Elementary School
1967-1976: High School (Gymnasium)
1976: Diploma (Abitur)
1976-1977: Compulsory Military Service
1977-1982: Study of biology at Tuebingen University, Germany
1982-1985: Ph.D. work at Federal Research Centre for Virus Diseases of Animals,
Tuebingen, Germany
1985: Ph.D. in Genetics
1986-1987: Postdoctoral Fellow at Vanderbilt University, Nashville, TN
Department of Microbiology
1988-today: Federal Research Centre for Virus Diseases of Animals
1990: Habilitation (prerequisite for professorship)
since 1994: Director of the Institute of Molecular Biology at the Federal Research Centre for Virus Diseases of Animals, Insel Riems, Germany
since 1996: President of the Federal Research Centre for Virus Diseases of Animals (renamed in 2004 'Friedrich-Loeffler-Institut')
since 1997: Professor of Virology at University of Greifswald
Scientific Work:
More than 300 peer-reviewed publications in international journals (listed in PubMed) on different aspects of infectious animal diseases.
Affiliations and expertise
Institute of Molecular Biology, Friedrich-Loeffler-Institut, Greifswald, GermanyRead Advances in Virus Research on ScienceDirect