Advances in Virus Research
- 1st Edition, Volume 94 - March 10, 2016
- Editors: Margaret Kielian, Karl Maramorosch, Thomas Mettenleiter
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 4 8 2 1 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 5 2 3 7 - 2
Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.… Read more
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Request a sales quotePublished since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.
- Contain contributions from leading authorities
- Informs and updates on all the latest developments in the field of virology
Virologists, microbiologists and infectious disease specialists.
Chapter One: Functional Genomic Strategies for Elucidating Human–Virus Interactions: Will CRISPR Knockout RNAi and Haploid Cells?
- Abstract
- 1 Introduction
- 2 Host–Virus Genetic Screens
- 3 RNAi Genetic Screening Technologies and Approaches
- 4 Haploid Cell Genetic Screening Technology and Approach
- 5 CRISPR/Cas9 Genetic Screening Technologies and Approaches
- 6 Comparison of HRV-HF Screens: Arrayed MORR RNAi Versus Pooled CRISPR/Cas9
- 7 Future Directions
- Acknowledgments
Chapter Two: Alphaherpesvirus Latency: A Dynamic State of Transcription and Reactivation
- Abstract
- 1 Introduction
- 2 A Working Definition of Latency
- 3 Model Systems to Study Alphaherpesvirus Latency
- 4 Establishment of Latency
- 5 The Dynamic State of Alphaherpesvirus Latency
- 6 Conclusions and Unanswered Questions
Chapter Three: Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport
- Abstract
- 1 Introduction
- 2 The Nucleus
- 3 Herpesvirus Nuclear Egress
- 4 Nuclear Egress as a Cellular Nuclear Export Mechanism
- 5 Alternative Herpesvirus Nuclear Escape Pathways
- 6 Nuclear Egress in Other Virus Families
- 7 Summary
- Acknowledgments
Chapter Four: Structure and Associated Biological Functions of Viroids
- Abstract
- 1 Introduction
- 2 Biophysical Properties as Basis for Functional Activity
- 3 Structure of Pospiviroidae
- 4 Structure of Avsunviroidae
- 5 Structural Motifs and Their Biological Function
- 6 Perspective
- Acknowledgments
Index
- No. of pages: 198
- Language: English
- Edition: 1
- Volume: 94
- Published: March 10, 2016
- Imprint: Academic Press
- Hardback ISBN: 9780128048214
- eBook ISBN: 9780128052372
MK
Margaret Kielian
KM
Karl Maramorosch
TM
Thomas Mettenleiter
Nationality: German
1963-1967: Elementary School
1967-1976: High School (Gymnasium)
1976: Diploma (Abitur)
1976-1977: Compulsory Military Service
1977-1982: Study of biology at Tuebingen University, Germany
1982-1985: Ph.D. work at Federal Research Centre for Virus Diseases of Animals,
Tuebingen, Germany
1985: Ph.D. in Genetics
1986-1987: Postdoctoral Fellow at Vanderbilt University, Nashville, TN
Department of Microbiology
1988-today: Federal Research Centre for Virus Diseases of Animals
1990: Habilitation (prerequisite for professorship)
since 1994: Director of the Institute of Molecular Biology at the Federal Research Centre for Virus Diseases of Animals, Insel Riems, Germany
since 1996: President of the Federal Research Centre for Virus Diseases of Animals (renamed in 2004 'Friedrich-Loeffler-Institut')
since 1997: Professor of Virology at University of Greifswald
Scientific Work:
More than 300 peer-reviewed publications in international journals (listed in PubMed) on different aspects of infectious animal diseases.