Advances in Extraction and Applications of Bioactive Phytochemicals

1st Edition - November 30, 2022
Authors: Mihir Kumar Purkait, Dibyajyoti Haldar, Prangan Duarah
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 8 5 3 5 - 9
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 8 5 3 6 - 6

Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds… Read more

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Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry’s perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more.

This book is a complete reference targeted at pharma researchers in academic and corporate environments and those willing to apply the most current extraction methods and health applications. Researchers in medicinal chemistry and chemical engineering will also benefit from this comprehensive resource.

Cover image
Title page
Table of Contents
Copyright
Author biography
Preface
Acknowledgment
Chapter 1. Pharmaceutical prospects of plant-based bioactive molecules
1.1. Introduction
1.2. Overview and structural compositions of naturally occurring bioactive phytochemical compounds
1.3. Analytical approaches for determining bioavailability and bioaccessibility of bioactive compounds
1.4. Commercialization of naturally occurring bioactive compounds
1.5. Conclusions and future perspectives
Chapter 2. Utilization of various parts of the plant for the extraction of phytochemicals and high-throughput screening techniques
2.1. Introduction
2.2. Different parts of plants used to produce the pharmaceutically active compound
2.3. High-throughput screening techniques for bioactive phytochemicals
2.4. Summary
Chapter 3. Conventional approaches for the extraction of bioactive compounds for pharmaceutical applications
3.1. Introduction
3.2. Conventional approaches for the extraction of bioactive compounds
3.3. Limitations associated with the conventional techniques
3.4. Summary
Chapter 4. Advancement in bioactive compound extraction from natural products for pharmaceutical applications
4.1. Introduction
4.2. Different extraction approaches
4.3. Future perspectives
4.4. Summary
Chapter 5. Neoteric solvents for extraction of bioactive phytochemicals
5.1. Introduction
5.2. Classification of different synthetic solvents
5.3. The emergence of solvent-free reactions in pharmaceutical industries
5.4. Summary
Chapter 6. Application and effectiveness of computational methods in improving the production of bioactive phytochemicals
6.1. Introduction
6.2. Insight into the progress of different computational tools
6.3. Insight into the advancement of molecular docking
6.4. Insight on molecular dynamics simulation for diseases and drug design
6.5. Summary
Chapter 7. Advances in encapsulation strategies for bioactive phytochemicals
7.1. Introduction
7.2. Different encapsulation processes for bioactive compounds
7.3. Future perspectives
7.4. Summary
Chapter 8. Applications of herb-derived bioactive phytochemicals
8.1. Introduction
8.2. Treatment of orthopedic diseases using herbal extracts
8.3. Influence of herbal plants as immunity boosters in the treatment of COVID-19 and other diseases
8.4. Effect of herbal nanoformulation in the applications of tropical delivery
8.5. Summary
Chapter 9. Pharmacologic and therapeutic aspects of various medicinal plants
9.1. Introduction
9.2. Medicinal effect of Nigella sativa in different fields
9.3. Selective plants in the treatment of different diseases
9.4. Medicinal efficacy of phytochemicals
9.5. Summary
Chapter 10. Applications of plant-derived metal nanoparticles in pharmaceuticals
10.1. Introduction
10.2. Biosynthesis of metallic nanoparticles for pharmaceutical application
10.3. Factors influencing the production of metallic nanoparticles from plant extract
10.4. Application of metallic nanoparticles in pharmaceuticals
10.5. Limitations and future perspectives
10.6. Summary
Chapter 11. Patents on naturally derived pharmaceuticals
11.1. Introduction
11.2. Patents on naturally derived pharmaceuticals
11.3. Summary
Index

Mihir Kumar Purkait

Dr. Mihir Kumar Purkait is a Professor in the Department of Chemical Engineering at the Indian Institute of Technology Guwahati, Assam, India. His current research activities are focused in four distinct areas viz. i) advanced separation technologies, ii) waste to energy, iii) smart materials for various applications, and iv) process intensification. In each of the area, his goal is to synthesis stimuli responsive materials and to develop a more fundamental understanding of the factors governing the performance of the chemical and biochemical processes. He has more than 20 years of experience in academics and research and published more than 300 papers in different reputed journals (Citation: >16,500, h-index = 75, i-10 index = 193). He has 12 patents and completed 43 sponsored and consultancy projects from various funding agencies.

Affiliations and expertise

Professor, Department of Chemical Engineering, Indian Institute of Technology Guwahati, Assam, India

Dibyajyoti Haldar

Dr. Dibyajyoti Haldar is an Assistant Professor in the Department of Biotechnology at Karunya Institute of Technology and Sciences (Deemed to be University), Coimbatore, India. He is a former Post-Doctoral Fellow at the Centre for the Environment, Indian Institute of Technology Guwahati (IITG), India. He obtained his Ph.D in Chemical Engineering from the National Institute of Technology Agartala (NITA), India, and his M.Tech in Environmental Science and Technology from the National Institute of Technology Durgapur (NITDGP), India. His research work includes conversion of lignocellulosic biomass into fermentable sugars, enzymatic hydrolysis, biofuels, formation of value-added products derived from agricultural wastes and processes kinetics and modelling. He has published more than 20 scientific research and review papers in various reputed International journals. He is the author of several book chapters and two books (ISBN: 9780128188019 and ISBN: 9780128235348) published in Elsevier. Dr. Haldar is the Review Editor for Frontiers in Chemistry journal (SCI indexed) in the Green and Sustainable Chemistry Section. He is the recipient of Most Cited Review Paper Award for his review article “A review on the production of fermentable sugars from lignocellulosic biomass through conventional and enzymatic route–A comparison” published & downloaded for the period 2016-2020 in International Journal of Green Energy organized by 13th International Green Energy Conference on 18th July, 2021 in Beijing, China. He also received International Teaching Excellence Award in Biochemical Engineering in Global Annual Education & Research Excellence Awards 2021 by Centre for Professional Advancement (CPACE, AP) on 18th December 2021. During his Ph.D., he received the Best Oral Presentation Award in a one-day workshop on ''Current Trends in Scientific Research" at Research Scholars' Day 2018 organized by the National Institute of Technology Agartala, India. He is a potential reviewer of various SCI-indexed International journals. He attended several conferences of National and International repute.

Affiliations and expertise

Assistant Professor, Department of Biotechnology, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu, India

Prangan Duarah

Prangan Duarah is a doctoral research fellow at the Centre for the Environment in the Indian Institute of Technology, Guwahati. He worked on a research project at the Indian Institute of Technology, Bombay, before joining IIT Guwahati as a research fellow. He graduated from North-Eastern Hill University in Shillong, India, with a B.Tech in Energy Engineering. His current field of studies focuses on naturally-derived pharmaceutical compounds and green nanomaterial synthesis for various applications. He is a recipient of the prestigious Prime Minister's Research Fellowship (PMRF), which is given to the country's most outstanding research scholars as a token of encouragement to pursue their research. He has published more than five journal papers and several book chapters in peer-reviewed international publications.

Affiliations and expertise

Centre for the Environment, Indian Institute of Technology Guwahati (IITG), India

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Advances in Extraction and Applications of Bioactive Phytochemicals

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