
Advances in Chemical Proteomics
- 1st Edition - October 22, 2021
- Imprint: Elsevier
- Editor: Xudong Yao
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 4 3 3 - 6
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 1 4 3 5 - 0
Advances in Chemical Proteomics provides essential concepts and recent applications on probes, tool compounds and concepts for chemical proteomics and then moves on to applicati… Read more
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Advances in Chemical Proteomics provides essential concepts and recent applications on probes, tool compounds and concepts for chemical proteomics and then moves on to applications, including solid-phase reagents, fragment screening, designer compounds and protein lipidation. As the second volume in the Developments in Organic Chemistry series, each chapter is written by experts in the field. Users will find this to be a valuable reference for organic chemists and chemical biologists who are interested in developing tool compounds and reagents to measure and interrogate proteome, develop drug leads, and measure off-target effects and drug toxicity.
Analytical chemists who are interested in better understanding organic chemistry behind commonly used reagents for quantitative proteomics and tools compounds in the emerging field of chemical proteomics will also benefit from this comprehensive resource on the topics presented.
- Provides an ideal, introductory book to chemical proteomics for organic chemists, pharmaceutical chemists and chemical biologists
- Includes advanced, recent applications and reviews in chemical proteomics
- Presents valuable work by a global team of experts from the field of proteomics
Organic chemists and chemical biologists who are interested in developing tool compounds and reagents to measure the proteome, develop drug leads, measure drug toxicity. Pharmaceutical scientists
1. Tool compounds for mass spectrometry-based chemical proteomics
2. Principles of proteomic reactions of covalent inhibitors
3. Reporter tags and chemistry for probe-reacted proteins
4. Chemical derivatization of peptides for quantitative proteomics
5. Database-searching strategies for probe-reacted proteins in a proteome
6. Solid-phase reagents for discovering inhibitors of kinases
7. Fragment screening for discovering covalent probes
8. Designer compounds for locational proteomics
9. Chemical proteomics for exploring protein lipidation Targeting Author: Edward Tate
10. Synthetic evolution of indocyanine green with the 2-nitroimidazole warhead for imaging of hypoxic tumor
- Edition: 1
- Published: October 22, 2021
- Imprint: Elsevier
- Language: English
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