Advances in Antiparasitic Therapies and Drug Delivery
- 1st Edition - November 21, 2023
- Editors: Prashant Kesharwani, Neelima Gupta
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 5 1 7 8 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 5 1 7 9 - 8
Advances in Antiparasitic Therapies and Drug Delivery systematically discusses the fundamentals, principles, and methods of molecular mixing and reaction process intensifi… Read more
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Request a sales quoteAdvances in Antiparasitic Therapies and Drug Delivery systematically discusses the fundamentals, principles, and methods of molecular mixing and reaction process intensification. The book demonstrates, in detail, the implementation approach, process, and effectiveness of Higee chemical reaction engineering through novel industrial case studies that help industrial technicians to select reaction intensification technology route more scientifically. Sections cover the innovation and development process of Higee chemical reaction engineering, hydrodynamics behavior in Higee reactors, equipment design principles and methods, multiphase reaction of liquid-liquid, gas-liquid, gas-solid, gas-liquid-solid and reactive crystallization process intensification principles and effectiveness.
The book is a systematic summary of several national award and key projects, such as the State Technological Innovation Award, State Science and Technology Advancement Award, National Natural Science Foundation of China, National key R&D Program of China, National ‘‘863’’ Program of China, National ‘‘973’’ Program of China and also some international cooperation.
- Handles high gravity process intensification technology
- Covers theoretical innovation in multiphase reaction intensified by high gravity
- Presents engineering application cases in chemical engineering, materials science, ocean engineering, and environmental engineering
- Provides systematic understanding of high gravity process intensification through theories and industrial applications
(Under)graduate students, researchers and engineers in chemical engineering, materials science, environmental science, and biology
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Chapter 1. An introduction to the pathophysiology of parasitic infection
- Abstract
- Introduction
- Parasitic infections
- Conclusion
- Acknowledgment
- Declarations of Interest
- Funding
- References
- Chapter 2. Traditional medicine and natural products as antiparasitic agents
- Abstract
- Abbreviation
- Introduction
- Human parasitic diseases
- Alkaloids
- Essential oils
- Quinones
- Phenolics
- Terpenes
- Green nanoparticles as antiparasitic agents
- Conclusion
- References
- Chapter 3. Antiparasitic drugs: a definition and scope
- Abstract
- Introduction
- Antiprotozoal agents
- Antihelminthic agents
- Ectoparasiticides
- References
- Chapter 4. Ectoparasitic and endoparasitic drug delivery approaches for therapy
- Abstract
- Introduction
- Chiggers
- Bed bugs
- Lice
- Scabies
- Demodex
- Controlled drug delivery systems
- Hydrogel
- Microspheres
- Microemulsion
- Nanoemulgel
- Discussion and conclusion
- References
- Chapter 5. Microneedles in antiparasitic drug delivery applications
- Abstract
- Introduction
- Overview of antiparasitic drugs and challenges
- Discussion and conclusion
- References
- Chapter 6. Nanotechnology: an approach to faster diagnosis of parasitic infections
- Abstract
- Introduction
- Ectoparasites
- Helminth parasites
- Protozoan parasite
- Correlation of nanotechnology and parasitic-induced diseases diagnosis: current and future perspectives
- Conclusion
- Acknowledgment
- Declarations of Interest
- Funding
- Author Contributions
- Reference
- Chapter 7. Nanomedicine for parasitic helminth infections
- Abstract
- Abbreviations
- Introduction
- A brief overview through helminth and parasitic worms
- Anthelmintic/nanotechnology and nanomedicine
- Conclusion
- References
- Chapter 8. Pathogenesis, treatments, and challenges associated with malaria and nanomedicines for antimalarial therapy
- Abstract
- Abbreviations
- Introduction
- Pathogenesis of malaria
- Current treatment options for malaria
- Challenges in malaria management
- Nanomedicines for antimalarial therapy
- Conclusion
- References
- Chapter 9. Repurposing antiparasitic drugs for the treatment of other diseases
- Abstract
- Introduction
- Search methods
- Antiparasitic drug; kinds of pharmacological aspect
- Evidences of antiparasitic drugs in the treatment of inflammatory disease
- Conclusion
- References
- Chapter 10. Marketed antiparasitic nanotechnology-based products and drawbacks
- Abstract
- Abbreviations
- Introduction
- Method of research
- Nanotechnology-based products
- Fungizone
- Abelcet
- AmBisome
- Amphotec
- Challenges of antiparasitic products based on nanotechnology
- Regulatory concerns
- Developmental and manufacturing cost
- Scale-up issues
- Conclusion
- Acknowledgment
- Funding
- Declarations of interest
- References
- Chapter 11. Fighting parasites during the post-antibiotic era
- Abstract
- Introduction
- Method of research
- Antibiotic therapy of parasitic infections
- Novel treatments of parasitic infections post-antibiotics
- Conclusion and future perspectives
- Funding
- References
- Chapter 12. Antimicrobial resistance and recent advancement to combat parasitic infections; development of resistance to antihelminthic/antiprotozoal and antimalarial drugs
- Abstract
- Antiparasitic control agents
- Development of resistance in Plasmodium falciparum
- Antiparasitic agents for amebiasis and other parasites
- Chemotherapeutic agents against Leishmaniasis
- Resistance against antiparasitic agents in other parasites
- Chemotherapeutic agents against trypanosomes (Table 12.5)
- The emergence of resistance toward antiparasitic agents
- Selection pressure of the drug
- Factors related to antiparasitic agents
- Ecological and geographical factors
- Drug pressure
- Refugia parasites
- Competition or fitness
- Evading the action of the drugs
- Measures to combat antiparasitic resistance
- References
- Chapter 13. Aptamers as an emerging concept for the management of parasitic diseases
- Abstract
- Introduction
- SELEX technology
- Increasing efficacy of the aptamers
- Applications of aptamers
- Aptamers targeting Plasmodium spp
- Aptamers targeting Cryptosporidium parvuum
- References
- Chapter 14. Where do we stand? Insight on patented products and those under clinical trials
- Abstract
- Introduction
- Search methods
- Novel antiparasitic drug properties
- Recent clinical trial on antiparasitics drugs
- Recent FDA-approved drugs; what are their features?
- Consideration of future antiparasitic drugs
- Conclusion
- References
- Chapter 15. Challenges and opportunities in antiparasitic drug discovery and delivery
- Abstract
- Introduction
- Discussion and conclusion
- References
- Chapter 16. The future of antiparasitic therapy
- Abstract
- Introduction
- Parasites and human health
- Antiparasitic drugs
- Improving healthcare through antiparasitic therapy
- Role of clinician in drug therapy
- References
- Index
- No. of pages: 600
- Language: English
- Edition: 1
- Published: November 21, 2023
- Imprint: Academic Press
- Paperback ISBN: 9780443151781
- eBook ISBN: 9780443151798
PK
Prashant Kesharwani
Dr. Prashant Kesharwani is an assistant professor of pharmaceutics at School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 300 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, most prestigious “Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community.
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