Advanced Neuroimaging in Brain Tumors, An Issue of Radiologic Clinics of North America

1st Edition, Volume 59-3 - May 13, 2021
Editor: Sangam Kanekar
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 9 4 2 1 - 3
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 9 4 2 2 - 0

This issue of Radiologic Clinics focuses on Advanced Neuroimaging in Brain Tumors and is edited by Dr. Sangam Kanekar. Articles will include: Imaging findings of new entities and… Read more

Advanced Neuroimaging in Brain Tumors, An Issue of Radiologic Clinics of North America

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This issue of Radiologic Clinics focuses on Advanced Neuroimaging in Brain Tumors and is edited by Dr. Sangam Kanekar. Articles will include: Imaging findings of new entities and patterns in brain tumor: IDH mutant, IDH wildtype, Codeletion, and MGMT methylation; CT and MR perfusion imaging in neuro-oncology; Application of diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI) in the pre- and post-surgical evaluation of brain tumor; Clinical applications of magnetic resonance spectroscopy (MRS) in of brain tumors: grading and recurrence; Cellular and molecular imaging with PET and SPECT in brain tumors; Role of Functional MRI (fMRI) in the presurgical mapping of brain tumor; Imaging surveillance of gliomas: role of advanced imaging techniques; Neoplastic meningitis and paraneoplastic syndrome—role of imaging; Imaging of neurologic injury following oncologic therapy; RadioGenomics of brain tumor; Imaging mimics of brain tumors; Imaging of tumor syndromes; and more!

Cover image
Title page
Table of Contents
Copyright
Contributors
CME Accreditation Page
Forthcoming Issues
Preface
Imaging Findings of New Entities and Patterns in Brain Tumor: Isocitrate Dehydrogenase Mutant, Isocitrate Dehydrogenase Wild-Type, Codeletion, and MGMT Methylation
Key points
Background
Genetic factors
Molecular genetics of glioblastoma and gliomagenesis
Imaging
Role of MR imaging
Key imaging findings
Other molecular markers and mutations in diffuse gliomas
Treatment, prognosis, and isocitrate dehydrogenase mutations
Prognosis
Summary
Clinics care points
Clinical Review of Computed Tomography and MR Perfusion Imaging in Neuro-Oncology
Key points
Introduction
Computed tomography perfusion
Perfusion MR imaging
Clinical use of perfusion imaging in neuro-oncology
Summary
Clinics care points
Application of Diffusion Weighted Imaging and Diffusion Tensor Imaging in the Pretreatment and Post-treatment of Brain Tumor
Key points
Introduction
Diffusion weighted imaging
Diffusion tensor imaging
Clinics care points
Clinical Applications of Magnetic Resonance Spectroscopy in Brain Tumors: From Diagnosis to Treatment
Key points
Introduction
Imaging technique
Metabolites
Clinical relevance: diagnosis
Clinical relevance: tumor grading
Clinical relevance: follow-up
Limitations
Future directions
Summary
Clinics care points
Cellular and Molecular Imaging with SPECT and PET in Brain Tumors
Key points
Introduction
Single-photon emission computed tomography
Positron emission tomography
Tracing glucose metabolism
Amino acid metabolism
Targeting cell membrane components
Targeting hypoxia
Tracing somatostatin receptor
Prostate-specific membrane antigen–expressing tumors
Summary
Clinics care points
Role of Functional Magnetic Resonance Imaging in the Presurgical Mapping of Brain Tumors
Key points
Introduction
Background of functional magnetic resonance imaging (blood oxygenation level–dependent signal, functional magnetic resonance imaging study design)
Functional magnetic resonance imaging: current clinical applications
Functional magnetic resonance imaging applications in brain tumor surgery
The general workflow for clinical functional magnetic resonance imaging
Commonly used tasks
Resting state functional magnetic resonance imaging
Application of resting-state functional magnetic resonance imaging in presurgical mapping
Summary
Clinics care points
Imaging Surveillance of Gliomas: Role of Basic and Advanced Imaging Techniques
Key points
Introduction
Treatment and response assessment of high-grade gliomas
Treatment response assessment and surveillance of low-grade gliomas
Summary
Clinics care points
Neoplastic Meningitis and Paraneoplastic Syndromes
Key points
Introduction
Pathophysiology
Clinical features
Diagnosis
Paraneoplastic syndromes
Other paraneoplastic disorders
Evaluation of the paraneoplastic neuronal disorder
Antibody testing
Special antibodies and paraneoplastic encephalitis
Imaging of Neurologic Injury following Oncologic Therapy
Key points
Introduction
Radiation therapy
Chemotherapy
Combination therapies
Immunotherapy
Pediatric brain
Summary
Radiogenomics of Gliomas
Key points
Introduction
Overview of glioma biology
Definitions and terminology
Molecular characteristics of gliomas
Approach to radiogenomic analysis
Radiogenomic studies using semantic features
Molecular classification
Radiogenomic studies using radiomic features
Limitations and future directions
Summary
Clinics care points
Imaging Mimics of Brain Tumors
Key points
Introduction
Imaging findings
Laboratory test pearls and pitfalls
Summary
Clinics care points
Imaging of Tumor Syndromes
Key points
Introduction
Cancer predisposition syndromes
Clinics care points

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Advanced Neuroimaging in Brain Tumors, An Issue of Radiologic Clinics of North America

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Sangam Kanekar