A Practice of Anesthesia for Infants and Children
- 7th Edition - May 18, 2024
- Editors: Charles J. Cote, Jerrold Lerman, Brian Anderson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 8 2 5 6 0 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 2 5 6 1 - 0
Covering everything from preoperative evaluation to neonatal emergencies to the PACU, Coté, Lerman and Anderson’s A Practice of Anesthesia in Infants and Children, 7th Edition,… Read more
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Request a sales quoteCovering everything from preoperative evaluation to neonatal emergencies to the PACU, Coté, Lerman and Anderson’s A Practice of Anesthesia in Infants and Children, 7th Edition, features state-of-the-art advice on the safe, effective administration of general and regional anesthesia and sedation strategies for young patients. This text reviews underlying scientific information, addresses preoperative assessment and anesthesia management in detail, and provides guidelines for postoperative care, emergencies, and special procedures. Comprehensive in scope and thoroughly up to date, this edition delivers unsurpassed coverage of every key aspect of pediatric anesthesia.
- Presents must-know information on standards, techniques, and the latest advances in pediatric anesthesia from global experts in the field.
- Contains thoroughly updated content throughout, with new contributors to lend a fresh perspective, updated figures and tables, and the latest information on perioperative fluid management, pharmacology, interventional devices, resuscitation, and more.
- Covers key topics such as anesthetizing children with cancer, neonatal and pediatric emergencies, the obese child and bariatric surgery, interventional devices for children with congenital heart defects, cardiopulmonary resuscitation, simulation in pediatric anesthesia, patient safety and quality assurance, and more.
- Features an extensive video library of pediatric anesthesia procedures, particularly difficult airway management strategies, new positioning devices, cardiac assist devices in action, management of burn injuries, how to perform ultrasound-guided regional anesthesia blocks and techniques, and much more.
- Essentials chapters provide focused input from expert subspecialty pediatricians who share the latest information concerning hematology, pulmonology, oncology, hepatology, nephrology, and neurology.
- Includes a laminated pocket reference guide with essential, practical information, and key references at the end of each chapter that provide a quick summary for review.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Pediatric Anesthesiologists, Anesthesiologists (42,000 in US),
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of Contributors
- Preface
- Acknowledgments
- Video contents
- List of Illustrations
- List of Tables
- SECTION I. Introduction
- 1. Growth and development
- Normal and abnormal growth and maturation
- Gestational age assessment
- Airway and respiratory system
- Cardiovascular system
- Renal system
- Digestive and endocrine system
- Hematopoietic and immunologic system
- Neurologic development and cognitive development issues
- The skin and thermoregulation
- Acknowledgment
- Annotated references
- References
- 2. Preoperative evaluation, premedication, and induction of anesthesia
- Preparation of children for anesthesia
- Premedication and induction principles
- Induction of anesthesia
- Special problems
- Acknowledgment
- Annotated references
- References
- 3. Ethical issues in pediatric anesthesiology
- Implicit and explicit bias
- Informed consent
- End-of-life issues
- Clinical and academic practice issues
- Annotated references
- References
- SECTION II. Drug and Fluid Therapy
- 4. Pharmacogenomics
- Historical perspectives
- Basic concepts and nomenclature
- Hepatic metabolism and developmental pharmacogenetics
- Genomics of drug metabolism, exposure, and effects
- Pharmacogenomics of pain and analgesia
- Genetic variations affecting opioid pharmacokinetics
- Genetic variations affecting opioid pharmacodynamics
- Genes of addiction
- Nonsteroidal antiinflammatory drugs and genetics
- Acetaminophen and genetics
- Acute and chronic postsurgical pain – genetics and epigenetics
- Pharmacogenomics affecting anesthesia
- Perioperative outcomes
- Ancestry/race and genetics
- Pharmacogenomics methods
- Genetic counseling
- Clinical translation: Bench to bedside: Where are we now?
- Conclusion
- Annotated references
- References
- 5. Pharmacology of drugs used in children
- Pharmacokinetic principles and calculations
- Population modeling
- Pediatric pharmacokinetic considerations
- Pharmacodynamic models
- Linking pharmacokinetics with pharmacodynamics
- Drug distribution
- Absorption
- Bioavailability
- Metabolism and excretion
- Pharmacodynamics in children
- Drug interactions
- The drug approval process, the package insert, and drug labeling
- Inhalation anesthetic agents
- Oxygen
- Intravenous anesthetic agents
- Neuromuscular blocking drugs
- Depolarizing neuromuscular blocking drugs
- Intermediate-acting nondepolarizing neuromuscular blocking drugs
- Long-acting nondepolarizing neuromuscular blocking drugs
- Antagonism of neuromuscular blocking drugs
- Neuromuscular blocking drugs in special situations
- Opioids
- Acetaminophen
- Nonsteroidal antiinflammatory agents (NSAIDs)
- Benzodiazepine sedatives
- Other sedatives
- Antihistamines
- Antiemetics
- Anticholinergics
- Antagonists
- Annotated references
- References
- 6. Total intraven ous anesthesia and target-controlled infusion
- Pharmacokinetic and pharmacodynamic principles
- Pharmacodynamic interaction models
- Depth of anesthesia monitoring
- Common TIVA drugs
- Achieving the target concentration in a multicompartment model
- A practical approach in children
- Ready mixes
- Special cases
- The future
- Annotated references
- References
- 7. Fluid management
- Regulatory mechanisms: Fluid volume, osmolality, and arterial pressure
- Maturation of fluid compartments and homeostatic mechanisms
- Fluid and electrolyte requirements
- Intraoperative fluid management
- Postoperative fluid management
- Pathophysiologic states and their management
- Annotated references
- References
- 8. Essentials of hematology
- The basics
- Hemolytic anemias
- Hemoglobinopathies
- Thrombocytopenia
- Coagulation disorders
- Hematologic malignancies
- Annotated references
- References
- 9. Perioperative management of the oncology patient
- Principles of cancer therapy
- Preoperative considerations by organ system
- Hematopoietic stem cell transplant
- Preoperative laboratory testing and evaluation
- Perioperative considerations
- Transfusion considerations
- Effects of anesthetic agents on perioperative immunomodulation
- Annotated references
- References
- 10. Strategies for blood product management, reducing transfusions, and massive blood transfusion
- Blood volume
- Blood components and alternatives
- Massive blood transfusion
- Methods to reduce patient exposure to allogeneic blood components
- Acknowledgment
- Annotated references
- References
- SECTION III. The Chest
- 11. Essentials of pulmonology
- Respiratory physiology
- Preoperative assessment
- Pulmonary function tests
- Perioperative etiology and epidemiology
- Annotated references
- References
- 12. The pediatric airway
- Developmental anatomy of the airway
- The larynx
- Physiology of the respiratory system
- Evaluation of the airway
- Airway management: The normal airway
- Airway management: The abnormal airway
- Acknowledgments
- Annotated references
- References
- 13. Anesthesia for thoracic surgery
- General perioperative considerations
- Techniques for single-lung ventilation in infants and children
- Surgical lesions of the chest
- Point-of-care ultrasound pulmonary exam
- Annotated references
- References
- SECTION IV. The Heart
- 14. Essentials of cardiology
- Congenital heart disease
- Acquired heart disease
- Heart failure in children
- Syndromes, associations, and systemic disorders: Cardiovascular disease and anesthetic implications
- Selected vascular anomalies and their implications for anesthesia
- Evaluation of the child with a cardiac murmur
- Basic interpretation of the electrocardiogram in children
- Essentials of cardiac rhythm interpretation and acute management of arrhythmias in children
- Pacemaker and defibrillator therapy in the pediatric age group
- Diagnostic modalities in pediatric cardiology
- Perioperative considerations for children with cardiovascular disease
- Annotated references
- References
- 15. Anesthesia for children undergoing heart surgery
- Preoperative evaluation
- Perioperative challenges in pediatric cardiac anesthesia
- Anesthesia management for surgery requiring cardiopulmonary bypass
- Control of systemic and pulmonary vascular resistances during anesthesia
- Anesthetic drugs used in pediatric cardiac anesthesia
- Regional anesthesia and analgesia
- Fast track and enhanced recovery after surgery
- Stress response to cardiac surgery
- Anesthesia considerations for specific cardiac defects
- Transport and transfer to a pediatric intensive care unit
- Annotated references
- References
- 16. Cardiac physiology and pharmacology
- Cardiovascular physiology
- Incidence and prevalence of congenital heart disease
- Pathophysiologic classification of congenital heart disease
- Special situations
- Cardiovascular pharmacology
- Annotated references
- References
- 17. Cardiopulmonary bypass and management
- Basic aspects of cardiopulmonary bypass
- Special coagulation and hematologic problems
- A perspective on blood preservation: Cardiopulmonary bypass in Jehovah’s witness patients
- Myocardial protection
- Phases of cardiopulmonary bypass
- Particular aspects of management on cardiopulmonary bypass
- Prebypass anesthetic management
- Anesthesia on cardiopulmonary bypass
- Special techniques
- Effects of cardiopulmonary bypass
- Transport to the intensive care unit
- Fast tracking and recovery
- Annotated references
- References
- 18. Medications for hemostasis
- Physiology of coagulation
- Developmental coagulation
- Coagulopathy and major surgery
- Alterations in hemostasis during pediatric cardiac surgery
- Thrombosis and heart surgery
- Medications used for hemostasis
- New drug development
- Acknowledgment
- Annotated references
- References
- 19. Mechanical circulatory support
- Learning systems and databases
- Indications for mechanical circulatory support
- Contraindications
- The devices
- Extracorporeal membrane oxygenation
- Ventricular assist devices
- Perioperative management of mechanical circulatory support
- Outcomes and complications
- Future directions
- Annotated references
- References
- 20. Interventional cardiology
- Types of procedures performed
- Complications and limitations of procedures
- Anesthesia
- Acknowledgment
- Annotated references
- References
- 21. Anesthesia for noncardiac surgery in children with congenital heart disease
- Selected congenital heart defects
- Perioperative considerations in children with CHD during noncardiac surgery
- Perioperative problems and special considerations
- Types of noncardiac surgical procedures in children with CHD and implications for anesthesia care
- Outcomes of noncardiac surgery in children with CHD and risk analysis
- Annotated references
- References
- SECTION V. The Brain and Glands
- 22. Essentials of neurology and neuromuscular disorders
- General considerations
- Static neurologic disorders
- Progressive neurologic disorders
- Neuromuscular disorders
- Nerve palsies
- Epilepsy
- Annotated references
- References
- 23. Surgery, anesthesia, and the immature brain
- Background
- Normal brain development
- Effects of anesthetic exposure on the developing brain
- Putative mechanisms for neurotoxicity
- Specific anesthetic and sedative agents
- Exposure time, dose, and anesthetic combinations
- Deleterious effects of untreated pain and stress
- Potential alleviating strategies
- Anesthetic neuroprotection
- Critical evaluation of animal studies and interspecies comparisons
- Long-term outcome in children exposed to anesthesia and surgery
- Outcome after exposure to anesthesia outside of the operating room
- Limitations of the available clinical studies
- Future research
- Recommendations for clinical practice
- Annotated references
- References
- 24. Pediatric neurosurgical anesthesia
- Pathophysiology
- Management of anesthesia
- Special situations
- Annotated references
- References
- 25. Essentials of endocrinology
- Diabetes mellitus
- Diabetes insipidus
- Syndrome of inappropriate antidiuretic hormone secretion
- Thyroid disorders
- Parathyroid and calcium disorders
- Adrenal disorders
- Pheochromocytoma
- Annotated references
- References
- SECTION VI. The Abdomen
- 26. Essentials of nephrology
- Renal physiology
- Disease states
- Intraoperative management
- Annotated references
- References
- 27. General abdominal and urologic surgery
- General principles of abdominal surgery
- General principles of urologic surgery
- Laparoscopic surgery
- Robot-assisted surgery
- Specific general surgical and urologic conditions
- Bariatric surgery in children
- Acknowledgments
- Annotated references
- References
- 28. Essentials of hepatology
- Anatomy
- Principles of hepatic drug metabolism
- Anesthetic agents
- Anesthetic effects on hepatic cellular functions
- Perioperative considerations in liver disease
- Annotated references
- References
- 29. Organ transplantation
- Liver transplantation
- Renal transplantation
- Cardiac transplantation
- Pediatric lung and heart-lung transplantation
- Acknowledgements
- Annotated references
- References
- SECTION VII. Other Surgeries
- 30. Orthopedic and spine surgery
- Scoliosis surgery
- Risk minimization and improving outcome from surgical intervention
- Spinal cord injury during surgery
- The patient journey: Preparation, planning, and pathways
- Anesthetic and intraoperative management
- Tourniquets
- Acute bone and joint infections
- Common syndromes
- Annotated references
- References
- 31. Otorhinolaryngologic procedures
- Anesthesia for otologic procedures
- Anesthesia for rhinologic procedures
- Adenotonsillectomy
- Anesthesia for endoscopy
- Upper airway obstruction
- Tracheotomy
- Airway trauma and inhalational injury
- Laryngeal clefts
- Laryngotracheal reconstruction
- Acknowledgments
- Annotated references
- References
- 32. Ophthalmologic surgery
- Preoperative evaluation
- Common ophthalmologic diagnoses requiring surgery
- Comorbidities encountered in ophthalmologic surgery
- Specific ophthalmologic procedures
- Acknowledgment
- Annotated references
- References
- 33. Plastic and reconstructive surgery
- Cleft lip and palate
- Craniosynostosis
- Orbital hypertelorism
- Midface procedures
- Hemifacial microsomia, Treacher Collins syndrome, and Goldenhar syndrome
- Orthognathic surgery
- Lymphatic malformations and hemangiomas
- Möbius sequence
- Brachial plexus surgery
- Otoplasty
- Congenital hand anomalies
- Tissue expanders
- Hairy pigmented nevi
- Cosmetic procedures
- Trauma
- Annotated references
- References
- 34. Burn injuries
- Pathophysiology
- Pharmacology
- Resuscitation and initial evaluation
- Guidelines to anesthetic management
- Acknowledgment
- Annotated references
- References
- SECTION VIII. Emergencies
- 35. The extremely premature infant (micropremie) and common neonatal emergencies
- Physiology of prematurity related to anesthesia
- Anesthetics and the neonate/premature infant
- Neonatal surgical emergencies
- Emergency surgery
- Annotated references
- References
- 36. Fetal intervention and the EXIT procedure
- Indications for fetal intervention
- Maternal physiology
- Fetal physiology and monitoring
- Anesthetic considerations
- The EXIT procedure
- Future directions
- Acknowledgment
- Annotated references
- References
- 37. Trauma and mass casualties
- Epidemiology of pediatric trauma
- Nonaccidental trauma
- Prehospital care of the pediatric trauma patient
- Emergency department evaluation and management of the pediatric trauma patient
- Intraoperative management of the pediatric trauma patient
- Mass casualty events
- Cricoid pressure
- Pain management
- Future directions in pediatric trauma
- Acknowledgment
- Annotated references
- References
- 38. Cardiopulmonary resuscitation
- Historical background
- Epidemiology, prevention, and outcome of in-hospital cardiopulmonary arrest
- Diagnosis of cardiac arrest
- Mechanics of cardiopulmonary resuscitation
- Defibrillation and cardioversion
- Vascular access and monitoring during cardiopulmonary resuscitation
- Medications used during cardiopulmonary resuscitation
- Special cardiac arrest situations
- Adjunctive cardiopulmonary resuscitation techniques
- Post-resuscitation stabilization (post–cardiac arrest care)
- The 2020 AHA pediatric advanced life support guidelines update
- Annotated references
- References
- 39. Malignant hyperthermia
- Clinical presentation
- Patient evaluation and preparation
- Monitoring
- Pathophysiology and laboratory testing
- Management of malignant hyperthermia
- Stress-triggered malignant hyperthermia
- Genetics
- Physiology
- Laboratory diagnosis
- Other disorders and malignant hyperthermia
- Acknowledgment
- Annotated references
- References
- SECTION IX. Pain
- 40. Regional anesthesia
- Pharmacology and pharmacokinetics of local anesthetics
- Ultrasound equipment
- Essentials of musculoskeletal ultrasound imaging
- Identification of structures
- Special ultrasound techniques
- Use of a nerve stimulator
- Specific procedures
- Intravenous regional anesthesia
- Acknowledgment
- Annotated references
- References
- 41. Acute pain
- Developmental neurobiology of pain
- Pain assessment
- Strategies for pain management
- Pharmacologic treatment of pain
- Pain management in the cognitively impaired child
- Annotated references
- References
- 42. Chronic pain
- Chronic pain in children
- The multidisciplinary approach
- General approach to management
- Chronic pain conditions
- Pain pharmacotherapy
- Complementary therapies
- Annotated references
- References
- SECTION X. Special Topics
- 43. Anesthesia outside the operating room
- Standards and guidelines
- Off-site anesthesia: Structure
- Quality assurance of anesthesia services and outcome in the off-site areas
- Anesthetic risk in non–operating room anesthesia
- Logistics of managing acute emergencies and cardiopulmonary arrest outside the operating room
- Anesthetic options for non–operating room procedures and tests in children
- Difficult airway management in the non–operating room (off-site) environment
- Specific locations for non–operating room anesthesia
- Acknowledgment
- Annotated references
- References
- 44. Sedation for diagnostic and therapeutic procedures outside the operating room
- The evolution of pediatric sedation and the anesthesiologist’s role
- Sedation depth
- The concept of “safety”
- Guidelines
- Goals of sedation
- Specific sedation techniques
- Future of pediatric sedation
- Acknowledgment
- Annotated references
- References
- 45. The post anesthesia care unit and beyond
- Perioperative environment
- Central nervous system
- Respiratory system
- Cardiovascular system
- Renal system
- Gastrointestinal system
- Postoperative care and discharge
- Beyond PACU: Postoperative monitoring in the general care setting
- Annotated references
- References
- 46. Procedures for vascular access
- Infection control practice
- Safety measures
- Venous cannulation
- Vascular access specialist team
- Arterial cannulation
- Acknowledgment
- Annotated references
- References
- 47. Infectious disease considerations for the operating room
- Causative agent
- Host
- Methods of transmission
- Coronavirus and future pandemics
- Strategy for preventing infection transmission in health care institutions
- Measures for prevention of infection transmission in the operating room
- Annotated references
- References
- 48. Pediatric anesthesia in developing countries
- The child
- Human resources
- Pathology
- Drugs
- Blood safety
- Equipment
- Visiting providers
- Annotated references
- References
- 49. Pediatric equipment and monitoring
- Heating and cooling systems
- Patient warming
- Intravenous therapy
- Airway apparatus
- Intubation equipment
- Suction devices
- Anesthesia workstation
- Equipment cart
- Defibrillator and external pacemakers
- Ultrasound for regional anesthesia and vascular cannulation
- Monitoring equipment
- Purchasing anesthesia equipment
- Annotated references
- References
- 50. Simulation in pediatric anesthesia
- Simulation-based training in anesthesia
- What is simulation?
- Technologies used in simulation
- Applications of simulation in perioperative pediatric education
- Comparing traditional learning with simulation-based learning
- Aspects of a high-fidelity simulation
- What is a debriefing?
- Annotated references
- References
- Index
- Drug card
- No. of pages: 1416
- Language: English
- Edition: 7
- Published: May 18, 2024
- Imprint: Elsevier
- Hardback ISBN: 9780323825603
- eBook ISBN: 9780323825610
CC
Charles J. Cote
Affiliations and expertise
Professor of Anaesthesia, Harvard Medical School; Director of Clinical Research, Division of Pediatric Anesthesia, MassGeneral Hospital for Children; Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, MAJL
Jerrold Lerman
Affiliations and expertise
Clinical Professor, Department of Anesthesiology, University of Rochester, Rochester, NY; Department of Anesthesiology, Children's Hospital of Buffalo, Buffalo, NY, USABA
Brian Anderson
Affiliations and expertise
Professor, Anaesthesiology, University of Auckland; Paediatric Anaesthetist and Intensivist, Paediatic Intensive Care Unit, Auckland Children's Hospital, Auckland, New Zealand