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3D Printing in Medicine
- 2nd Edition - October 18, 2022
- Editor: Deepak M. Kalaskar
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 9 8 3 1 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 0 2 2 0 - 5
3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercia… Read more
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Request a sales quote3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more.
This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand.
- Reviews a broad range of biomedical applications of 3D printing biomaterials and technologies
- Provides an interdisciplinary look at 3D printing in medicine, bridging the gap between engineering and clinical fields
- Includes completely updated content with additional new chapters, covering topics such as organs-on-chips, bioprinting regulations, intellectual properties, medical standards in 3D printing, and more
Materials scientists, engineers and biomedical engineers. Clinical scientists with an interest in 3D printing. Additive manufacturing R&D groups
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- 1. Introduction to three-dimensional printing in medicine
- Abstract
- 1.1 3D printing is the latest industrial revolution
- 1.2 3D bioprinting in medicine
- 1.3 Advantages of 3D printing for medicine
- 1.4 Future of 3D printing in medicine
- 1.5 Regulation, intellectual property, ethics and standards for 3D printing in medicine
- References
- 2. 3D printing families: laser, powder, and nozzle-based techniques
- Abstract
- 2.1 Introduction
- 2.2 Classification of 3D printing techniques
- 2.3 Challenges and Food and Drug Administration regulations
- 2.4 Conclusions and future trends
- Acknowledgments
- References
- 3. Materials for 3D printing in medicine: metals, polymers, ceramics, and hydrogels
- Abstract
- 3.1 Introduction
- 3.2 Metals
- 3.3 Bioceramics and bioactive glasses
- 3.4 Polymers
- 3.5 Hydrogels
- 3.6 Composite materials
- 3.7 Materials for 4D bioprinting
- 3.8 Summary and outlook
- Acknowledgments
- References
- 4. 3D-printed and computational models: a combined approach for patient-specific studies
- Abstract
- 4.1 Introduction
- 4.2 Creation of patient-specific models: image reconstruction
- 4.3 Patient-specific models: 3D manufacturing
- 4.4 Computer simulations of patient-specific cardiovascular models
- 4.5 Patient-specific models: the current perspective of regulatory bodies and policy makers
- 4.6 Future perspective of patient-specific models in cardiovascular applications
- References
- 5. 3D printers for surgical practice
- Abstract
- 5.1 Introduction
- 5.2 Imaging to printed model: steps involved
- 5.3 Limitations of CT and MRI images for surgical planning
- 5.4 3D printed models for anatomical simulation for surgeons
- 5.5 Surgical planning of congenital anomalies
- 5.6 3D printed models for anatomical teaching
- 5.7 Tissue defect-specific implant design
- 5.8 3D printing for surgical templates and diagnostic tools
- 5.9 Advantages of 3D printed models
- 5.10 Challenges for 3D printed models
- 5.11 Legal and ethical issues for 3D printing in surgery
- 5.12 Conclusion
- References
- 6. Patient-specific 3D bioprinting for in situ tissue engineering and regenerative medicine
- Abstract
- 6.1 Patient-specific 3D printing
- 6.2 Current medical applications for 3D printing
- 6.3 Challenges and future advancements
- 6.4 Summary
- References
- 7. 3D-bioprinted in vitro disease models
- Abstract
- 7.1 Introduction
- 7.2 Bioinks
- 7.3 3D disease modeling
- 7.4 Concluding remarks and future prospects
- Acknowledgments
- References
- 8. 3D printed pharmaceutical products
- Abstract
- 8.1 Introduction
- 8.2 Pharmaceutical 3D printing
- 8.3 Active pharmaceutical ingredients synthesis and assessment using 3D printing
- 8.4 Conclusions
- References
- 9. High-resolution 3D printing for healthcare
- Abstract
- 9.1 Clinical need and context
- 9.2 High-resolution 3D printing
- 9.3 Types of high-resolution 3D printing
- 9.4 Fundamentals of micro/nanofluidics
- 9.5 Printing materials
- 9.6 Exemplar functional devices
- 9.7 Conclusions and future direcions
- References
- 10. (Bio)fabrication of microfluidic devices and organs-on-a-chip
- Abstract
- 10.1 Introduction
- 10.2 Design and manufacturing principles of an organ-on-a-chip
- 10.3 3D printing technologies for organ-on-a-chip
- 10.4 Application overview of 3D printed organ-on-a-chip systems
- 10.5 Conclusions and outlook
- References
- 11. Four-dimension printing in healthcare
- Abstract
- 11.1 Introduction
- 11.2 Transformation of 3D printing to 4D printing
- 11.3 Emergence of 4D printing
- 11.4 4D printing strategies
- 11.5 Benefits of 4D printing
- 11.6 Applications of 4D printing
- 11.7 Conclusion
- References
- 12. Present and future of standardization of additive manufacturing in the medical field
- Abstract
- 12.1 Introduction
- 12.2 Standards in medical devices
- 12.3 Specific additive manufacturing standards for the medical field
- 12.4 Additive manufacturing and medical device regulations
- 12.5 Future needs and conclusions
- References
- 13. Social and ethical considerations of bioprinted organs
- Abstract
- 13.1 Introduction
- 13.2 Prevailing stages in the development of bioprinting technology
- 13.3 Risks associated with bioprinting
- 13.4 Lack of regulatory guidance for 3D bioprinting
- 13.5 Concerns with testing 3D bioprinting in humans
- 13.6 Irreversibility and loss of opportunity for alternative treatment and replicability of treatment
- 13.7 Need for a new organized regulatory framework
- 13.8 Conclusion
- References
- Further reading
- 14. Medical 3D printing, intellectual property, and regulation
- Abstract
- 14.1 Introduction
- 14.2 Law and 3D printing in medicine
- 14.3 Intellectual property
- 14.4 Medical product regulation
- 14.5 Conclusion
- Acknowledgment
- References
- Index
- No. of pages: 422
- Language: English
- Edition: 2
- Published: October 18, 2022
- Imprint: Woodhead Publishing
- Paperback ISBN: 9780323898317
- eBook ISBN: 9780323902205
DK
Deepak M. Kalaskar
Deepak M. Kalaskar is Professor of Bioengineering in the Department of Ortho and MSK Science, Division of Surgery & Interventional Science, Faculty of Medical Sciences at University College London, United Kingdom. Professor Kalaskar is a multidisciplinary scientist with extensive experience in research, management, and education in biomedical engineering, biomaterials, and 3D fabrication technologies.
His research has been focused on the development of novel biomaterials and manufacturing processes to solve real-life problems in medicine. He has extensive experience in biomaterials, biocompatible coatings, 3D printing technologies, and design and development of medical devices and implants. He is working closely with several industries, clinical and academic collaborations for the development of new medical products and processes required for clinical translation. Some of his innovative 3D-printed medical devices are already used by patients. He is actively involved in running new clinical trials with various hospitals to bring 3D technologies from bench to bed side.
He is founder of the international research and educational platform supported by the British Council—the 3D Bioprinting Research Platform. The platform encourages multidisciplinary collaboration in 3D bioprinting research and education worldwide. He is the editor and author of four books in the field of 3D printing in medicine. Currently, he codirects the MSc program in Burns, Plastic and Reconstructive surgery at the University College London (UCL), to educate clinicians and scientists in translational medicine
Affiliations and expertise
Professor of Bioengineering, Department of Ortho and MSK Science, Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, UKRead 3D Printing in Medicine on ScienceDirect