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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Science collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

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31-40 of 489 results in All results

Functionalized Drug Delivery Systems

  • 1st Edition
  • June 1, 2025
  • Umesh Gupta + 1 more
  • English
“Functionalized Drug Delivery Systems” discusses the potential of various functionalized drug delivery systems such as polymeric micelles, dendrimers, metallic nanoparticles, and SMEDDS, compiling a list of various carriers with the functionalized potential for drug delivery and targeting. The contents of the book cover from basic concepts in drug delivery systems to surface engineering and dedicated chapters on specific techniques like liposomes, dendrimers, metal nanoparticles, polymeric micelles, niosomes and ethosomes, carbon nanotubes, self-micro and nano emulsifying systems. The final chapter covers the regulatory framework around functionalized drug delivery systems. Functionalized drug delivery systems have immense potential in improving drug absorption and targeted delivery. “Functionalized Drug Delivery Systems” is the perfect guide for pharmaceutical researchers in academia and corporate settings to delve into this area and start applying these techniques to their formulations. Graduate students can also benefit from the foundational content provided, and consolidated literature reviews presented.

Ligands for Targeted Drug Delivery

  • 1st Edition
  • June 1, 2025
  • Vikas Pandey + 3 more
  • English
"Ligands for Targeted Drug Delivery: basic fundamentals and applications" is a comprehensive reference focused on the numerous ways that drug carriers can be functionalized to target specific organs, tissues, cells, and sub-cellular compartments. The first chapter covers the basic concepts of targeted drug delivery, describing the multiple levels of targets and challenges. The next chapter discusses the approaches for target-specific drug delivery and is followed by a thorough overview of the challenges in design and application of ligands. Chapter four is dedicated to the ligand conjugation strategies and chemical processing. The following chapters discuss nanoparticles, and the main ligand classes with their respective applications. The final chapters discuss future prospects of the technology, and clinical aspects of ligand modified drug delivery systems. "Ligands for Targeted Drug Delivery: basic fundamentals and applications" is a key reference to drug delivery researchers dealing with the application of ligands to overcome challenges in delivering their active principles to the target structure. Biomedical engineers, materials scientists, and chemists can also benefit from the through description of ligand classes and their potential to improve drug delivery efficiency.

Natural Biopolymers for Drug Delivery

  • 1st Edition
  • May 1, 2025
  • Amit Kumar Nayak + 2 more
  • English
Natural Biopolymers for Drug Delivery thoroughly details the properties, benefits and challenges of using these biomaterials in drug delivery, with a strong focus on biocompatibility and reduction of unwanted interactions. An extensive range of natural biopolymers are explored, such as cellulose, chitosan, casein, gelatin, cashew gum, and many more. Biocompatibility, toxicity and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science and pharmacology, chemical engineering and clinical science.

Dissipative Particle Dynamics

  • 1st Edition
  • April 1, 2025
  • Alexander V. Neimark + 1 more
  • English
Dissipative particle dynamics (DPD) is one of the most efficient mesoscale simulation methodologies for studying soft matter systems. Applied to nanostructured materials of supramolecular architecture, DPD bridges the gap between the microscopic atomistic and macroscopic continuum length and time scales. The book comprehensively presents the fundamentals of DPD theoretical formulations and computational strategies and provides a practical guidance for applications of DPD models to various colloidal and interfacial phenomena involving phase separations, self-assembly and transport in complex fluids, polymeric, surfactant, nanoparticle, and biological systems. In addition, the book contains instructive advice on efficient implementation of the DPD models in open-source computational packages. Since introduction of the principles of DPD methodology thirty years ago, multiple efforts have been performed to improve the computational basis of DPD and to devise advanced versions and modifications of the original DPD framework. The progress in parametrization techniques that can reproduce engineering properties of experimental systems attracted a lot of interest from the industrial community longing to use DPD models to characterize, help design and optimize the practical products. While there are numerous research papers, there is no book dedicated to the dissipative particle dynamics that provides a critical review of various DPD formulations, serves as a comprehensive reference source of multifaceted interdisciplinary applications, and provides a practical guidance for efficient computational implementation.

The Organic Chemistry of Drug Design and Drug Action

  • 4th Edition
  • April 1, 2025
  • Richard B. Silverman + 3 more
  • English
The Organic Chemistry of Drug Design and Drug Action, Fourth Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.This new edition includes updates to all chapters, including new examples and many new figures. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage.This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.

Topical Dermal Drug Delivery

  • 1st Edition
  • April 1, 2025
  • Jitender Madan + 4 more
  • English
Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders.The book covers three major concepts. The skin anatomy and physiology part includes chapters focused on relevant information for drug delivery. The second part of the book deals with several recent topical dermal drug delivery systems, including computational methods, permeation enhancers, bio precursors, hydrogels, emugels, exosomes and several nanotechnology enabled systems. The third and final part covers scaling up, toxicity, clinical trials, and regulatory considerations.This is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the skin. Medical & Health Sciences researchers would also benefit from understanding the delivery systems covered in this book.

Fundamentals of Biologicals Regulation

  • 2nd Edition
  • April 1, 2025
  • Rebecca Sheets + 5 more
  • English
Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines serves as an introduction to the international regulatory arena in which biologicals are developed and offers an overview of the processes and insight into the scientific concepts underpinning global regulations.In this new edition the book provides additional coverage of Quality by Design, Combination Products, Target Product Profiles, Quality Target Product Profiles, RiskMAPs, Additional pre-IND assignment, Switching from reliance on in vivo to in vitro analytical methods. It also reflects the new developments and processes accelerated by the COVID-19 vaccine experience. New pedagogic elements and case studies have been added to improve learning outcomes for students.This book provides multiple levels of readership with guidance on basic concepts, a detailed look at regulatory challenges, and practical insight into how regulators consider regulatory science and regulatory process issues across various regions. Graduate students will benefit from the new pedagogic features. Regulatory professionals will have in Fundamentals of Biologicals Regulation: Vaccines and Biotechnology Medicines a complete guide to navigate through the approval process.

An Overview of FDA Regulated Products

  • 2nd Edition
  • April 1, 2025
  • Eunjoo Pacifici + 1 more
  • English
An Overview of FDA Regulated Products: From Drugs and Cosmetics to Food and Tobacco, Second Edition is a complete reference and learning resource for those working in the regulatory affairs or aspiring to join the industry.This book is fully updated to reflect recent advances in science and technology as well as new laws and regulations that have been implemented in recent years. Breakthroughs in cellular and gene therapy, immunotherapy, precision medicine, and digital health are constantly changing the face of healthcare and how these products are regulated. The updates brought about by the enactment of the 21st Century Cures Act and subsequent PDUFA Reauthorizations, as well as the signing into law the “Modernization of Cosmetic Regulation Act of 2022,” which will transform FDA’s oversight of cosmetics are fully reflected in all chapters of the book.An Overview of FDA Regulated Products: From Drugs and Cosmetics to Food and Tobacco, Second Edition provides graduate students and industry professionals with the key understanding of approval processes with the FDA and other country regulation organizations. Regulatory science Professionals working with not only Drugs, but Biologics, Medical Devices, Food and Additives, Cosmetics, Veterinary products, and Tobacco will benefit from the comprehensive overview of the regulatory environment established to approve these products.

Nanocarriers Based Colon Targeting

  • 1st Edition
  • April 1, 2025
  • Lalit Kumar + 1 more
  • English
"Nanocarriers Based Colon Targeting" unveils a groundbreaking exploration of nanotechnology's potential in revolutionizing drug delivery for colon-related ailments. Nowadays, an array of colonic diseases, including colorectal cancer, colonic polyps, ulcerative colitis, and inflammatory bowel syndrome, poses significant medical challenges. Conventional methods to deliver drugs to this system proves difficult, with limited efficacy and notable side effects. This book delves into the intricate complexities of colonic diseases, their pathophysiology, and epidemiology, to support pharmaceutical scientists in designing better drug delivery systems. Providing a comprehensive overview of the area, the chapters elucidate diverse targeting strategies, from time-dependent to microbiota-based drug delivery systems and explore receptor-based and magnetically assisted delivery mechanisms. Case studies dissected the working mechanisms behind polymeric nanoparticles, polymersomes, polymeric micelles, solid lipid nanoparticles, and other nanocarrier systems tailored for colon targeting. Additionally, the book delves into cutting-edge topics such as gold nanoparticles, supramagnetic iron oxide nanoparticles, and protein-peptide-based nanoparticles, highlighting their mechanisms, applications, and potential toxicities. Merging an overview of colonic pathophysiology with in-depth reviews of each nanomaterial used for drug delivery and practical case studies, "Nanocarriers Based Colon Targeting" is a complete reference for pharmaceutical scientists involved in elevating drug delivery precision and therapeutic efficacy to this organ system. Toxicologists, material scientists, research physicians and regulators can also benefit from the case studies developed by expert authors.