Head and Neck Oncology

DETAILED TOC
I. Introduction to modern head & neck cancer
II. Tools in the toolbox
a. Surgery:  Open surgery and Trans-Oral Robotic Surgery (TORS)
b. Systemic Therapy: Cytotoxic chemotherapy, targeted agents, immunotherapy
c. Radiation Therapy:  Conventional radiation, intensity-modulated radiation therapy, proton therapy, heavy ion therapy
III. Supportive services
a. Speech Pathology
b. Dental Oncology
c. Audiology
d. Palliative Oncology
IV. Case-based discussions (may be multiple cases for each type – will include evaluation, treatment options given case, and follow-up)
a. Oropharynx Cancer
i. HPV-positive

1. Early stage tonsil cancer

2. Advanced tonsil cancer

3. Early stage base of tongue cancer

4. Advanced base of tongue cancer
ii. HPV-negative

1. Tonsil cancer

2. Base of tongue cancer

3. Soft palate cancer

4. Pharyngeal wall cancer
b. Unknown Primary Cancer
i. HPV-positive
ii. HPV-negative or unknown
c. Oral Cavity Cancer
i. Early stage tongue cancer
ii. Advanced tongue cancer
iii. Floor of mouth cancer
iv. Early stage alveolar ridge/retromolar trigone cancer
v. Advanced stage alveolar ridge/retromolar trigone cancer
vi. Buccal cancer
d. Larynx Cancer
i. Early stage larynx cancer
ii. Advanced larynx cancer
e. Hypopharynx Cancer
i. Early stage hypopharynx cancer
ii. Advanced stage hypopharynx cancer
f. Salivary Gland Cancer
i. Parotid cancer

1. Adenoid cystic carcinoma

2. Mucoepidermoid carcinoma

3. Acinic cell carcinoma

4. Salivary duct carcinoma

5. Pleomorphic adenoma
ii. Submandibular cancer
iii. Minor salivary gland cancer

1. Adenoid cystic carcinoma

2. Mucoepidermoid carcinoma
g. Sinonasal Cancer
i. Esthesioneuroblastoma (olfactory neuroblastoma)
ii. Sinonasal undifferentiated carcinoma (SNUC)
iii. Adenocarcinoma
iv. Mucosal melanoma
h. Skin Cancer
i. Basal cell carcinoma

1. Early stage

2. Advanced stage
ii. Squamous cell carcinoma

1. Early stage

2. Advanced stage

3. Regionally metastatic
iii. Merkel cell carcinoma

1. Early stage

2. Regionally metastatic
iv. Melanoma

1. Early stage

2. Regionally metastatic
i. Recurrent Cancers
i. Locally recurrent
ii. Regionally recurrent
iii. Metastatic
V. Areas of ongoing research
VI. Conclusions
References