Fermentation Products

Preface

Guest Editorial: Problems and Trends in the Development of New Antibiotics and Other Useful Microbial Products

Section I. New Aspects of Secondary Metabolites


1. Possible Functions of the Peptide Antibiotics Tyrocidine and Gramicidin during Sporulation


2. The Role of Secondary Metabolism in Penicillium brevicompactum


3. A Study of Secondary Growth of Streptomyces griseoruber


4. Role of Plasmid Genes in Aureothricin Production


5. Function of Plasmids in Producers of Macrolides


6. Unstable Pleiotropic Mutation in Streptomyoes lavendulae


7. Localization of Antimycin a and Melanin Determinants in Auxotrophs of Streptomyoes sp. M-506 and in Their Prototrophic Revertants


8. Characterization of a Plasmid from Bacillus brevis ATCC 9999


9. Genetics of Penicillin Producing Organisms


10. Penicillin Production by Recombinant Strains of Penicillium chrysogenum Obtained by Fusion of Protoplasts


11. Fusion of Protoplasts of Bacillus Species


12. Studies on the Nature of Vacuoles in Protoplasts of Claviceps purpurea

Section II. Antibiotics


13. Cell-Free Biosynthesis of Macrolides and Other "Polyketide" Antibiotics


14. Cell-Free Biosynthesis of Peptide Antibiotics


15. Enzymology of Chloramphenicol Biosynthesis


16. Biosynthesis of Streptomycins


17. Enzymatic Synthesis of the Antibiotic Gramicidin S: Kinetics of Inhibition and Enzyme Destabilization


18. Terminal Steps of Patulin Biosynthesis in Penicillium urticae


19. Synthesis of Enniatins by a Multienzyme


20. Biosynthesis of Daunorubicin Glycosides: Analysis with Blocked Mutants


21. Fermentation and Biosynthesis of Sagamicin and Related Aminoglycosides in Micromonospora Sagamiensis


22. Characterization of Mutants of Streptomyoes Griseus Deregulated or Blocked in Candicidin Biosynthesis: Molecular Mechanism of Control of Antibiotic Biosynthesis


23. Study of the Molecular Mechanism of Phosphate Control of Candicidin Biosynthesis Using Phosphate-Deregulated Mutants


24. Regulation by Aromatic Amino Acids at the p-Aminobenzoic Acid Synthetase Level in S. griseus


25. Nitrogen Regulation of Penicillin G Biosynthesis in Penicillium chrysogenum


26. Carbon Catabolite Repression of Penicillin Biosynthesis


27. Regulation of Homocitrate Synthetase by Lysine in Relation to Penicillin G Biosynthesis


28. The Use of Different 1-Phenyl-N-Alkanes for Benzylpenicillin Biosynthesis by Penicillium chrysogenum


29. Analysis of the Spectrum of Secondary Metabolites of an Industrial Macrolide-producing Strain of Streptomyces hygroscopious


30. Stimulation of Leucomycin Production by Magnesium Phosphate and its Relevance to Nitrogen Catabolite Regulation


31. Regulation of the A40104 Fermentation-Production of A40104A, a Pleuromutilin Glycoside Antibiotic


32. Nitrogen Catabolite Regulation of Streptothricin Biosynthesis by Streptomyces noursei JA 3890 B


33. A New Aminoglycoside SC4-Antibiotic: Producing Organism, Fermentation and its Biological Properties


34. Studies on the Cosynthesis and Metabolic Regulation of Rifamycin SV

Section III. Amino Acids, Vitamins and Nucleotides


35. Regulation of Primary Metabolism


36. Aromatic Amino Acid Hyperproducing Mutants of Esoheriohia coli: Biochemistry, Genetics and Fermentation Kinetics


37. Utilisation de l'activite α-aminoamidasique d'une bacterie nitrilasique pour la production d'acides α-mines Stereospecifiques


38. Advances in Studies on Breeding of Amino Acid-Producing Strains in China


39. Vitamin Fermentations: B2 and B12


40. Extracellular Metabolites from Phototrophic Bacteria as Possible Intermediates in the Biosynthesis of Vitamin B12


41. Effect of Amino Acids on the Production of Biotin and the Mechanism of the Regulation of Biotin Biosynthesis in Sporobolomyces pararoseus 2553


42. Antimetabolite Substances from Bacillus ceveus


43. Control of Fermentative Production of Sugar Nucleotides and Cytidine Derivatives by Yeasts

Section IV. Microbial Enzymes


44. Production of Thermostable Cellulases and Raw Starch-Digestible Amylases by Fungi


45. Increased Production of Cellulase of Trichoderma reesei in STR and HRR by pH Cycling and Temperature Profiling


46. Cellulase Process Improvement and its Economics


47. 1,4-ß-Glucanases and 1,4-ß-Glucosidases from Penicillium janthinellum: Production, Location, Adsorption and Regulation


48. Process for the Production of Yeast-Lytic Enzymes and the Disruption of Whole Yeast Cells


49. Optimization of Cultivation Medium Composition for Lytic Enzyme Biosynthesis


50. ß-amylase Production by a Rifampin-Resistant, Asporogenous Mutant of Bacillus cereus and its Sporogenous Revertant


51. Production of Thermostable Alpha Amylase by Bacillus Apiarius CBML 152


52. Enzymatic Synthesis of 2H or 3H-Labeled Amino Acids with L-Methionine γ-Lyase


53. Enzymatic Oxidation of Methanol to Produce Formaldehyde and Hydrogen Peroxide


54. Isolation and Purification of Enzymes by Complexing with Liquid Ion Exchangers

Section V. Products from Immobilized Cells and Enzymes


55. Synthetic Prepolymer Methods for Immobilization of Biocatalysts. Application of Gel-Entrapped Microbial Cells to Bioconversions of Lipophilic Compounds in Hydrophobic Conditions


56. Industrial Applications of Fiber-Entrapped Enzymes


57. Microbial Sensors for Fermentation Control


58. Microencapsulation of Multi-Enzyme Systems


59. Catalytic Properties of Immobilized Cells of Methane-Oxidizing and Methanogenic Bacteria


60. Production of α-Keto Acids with Alginate-Entrapped Whole Cells of the Yeast Trigonopsis variabilis


61. Basic Trials on the Conversion of Cellulosic Material to Ethanol Using Yeast Coimmobilized with Cellulolytic Enzymes


62. Inhibition of Free and Immobilized Xanthine Oxidase by 6-(p-X-phenyl)pteridin-4-ones (X=H, Me, OMe, Cl, Br)


63. Photochemical Fuel Cell Using Immobilized Chloroplast-Clostridium butyricum

Section VI. Mycotoxins


64. Secondary Metabolites as Chemical Signals between Species in an Ecological Niche


65. Taxonomic Problems of Toxinogenic Molds


66. Genetic Perspective on Polyketides, Productivity, Parasexuality, Protoplasts, and Plasmids


67. Genetic Analysis of Aflatoxin Production by Aspergillus parasiticus


68. Convenient Production, Resolution, and Isotope Labeling of Cytochalasin Congeners

Section VII. Biopolymers


69. Microbial Polysaccharides


70. Scleroglucan Biopolymer Production, Properties, and Economics


71. The Effect of Citrate and Other Organic Acids in Xanthan Production


72. Emulsan Production in Acinetobacter Rag-1


73. Interaction of Acinetobacter Rag-1 Emulsan with Hydrocarbons


74. Biosurfactant and Surface Phenomena Associated with Corynebacterium lepus


75. Formation of Surface Active Glycolipids by n-Alkane Utilizing Microorganisms


76. Kinetics of the Biotechnological Production of Poly-ß-Hydroxybutyric Acid

Section VIII. Bioconversions


77. Degradation of Deoxycholic Acid by a Pseudomonas sp.


78. Production of Chenodeoxycholic Acid by Bioconversion of Dehydrocholic Acid


79. Kinetics and Optimization of Steroid Transformation in a Mixed Culture


80. Microbial Reduction of Carbon 1 and 2 Double Bond in l-α-Santonin (Microbial Transformation. XVI)


81. Isolation of l-Menthol from a Mixture of Racemic Menthols by Rhodotorula mucilaginosa and Bacillus Strains


82. Microbiological Hydroxylation of Patchoulol


83. Microbial Oxidation of ß-Myrcene

Section IX. Other Fermentations and Bioconversions


84. Factors Regulating Product Formation in Streptococcus lactis


85. Regulation of Citric Acid Production in Aspergillus niger


86. Production of 6-Aminopenicillanic Acid from Penicillin V and G by Bovista plumbea NRRL 3824 and Escherichia coli 5K (pHM 12)


87. Assay of Thymidine Phosphorylase in Whole Cell Suspensions of Escherichia coli

Contents of Other Volumes

Volume I. Scientific and Engineering Principles

Volume II. Fuels, Chemicals, Foods and Waste Treatment

Contents of "current Developments in Yeast Research" (ISY-5)

Author Index

Subject Index