Cutaneous Innervation
Proceedings of the Brown University Symposium on the Biology of Skin, 1959
- 1st Edition - January 1, 1960
- Imprint: Pergamon
- Editor: William Montagna
- Language: English
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 0 9 3 8 5 - 7
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 3 3 3 4 - 5
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 8 0 8 8 - 2
Advances in Biology of Skin, Vol. I: Cutaneous Innervation focuses on the biology of skin, including the chemistry of the ground substance of the dermis to the biology of… Read more
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Request a sales quoteAdvances in Biology of Skin, Vol. I: Cutaneous Innervation focuses on the biology of skin, including the chemistry of the ground substance of the dermis to the biology of sebaceous glands. The selection first offers information on the pattern of cutaneous innervation of the human hand, foot, and breast and similarities in cutaneous nerve end-organs. Discussions focus on the methods of study, observations, histochemical reactions, and function of end-organs. The text then examines the autonomic innervation of the skin, cholinesterases in the cutaneous nerves of man, and the relation of nerve fiber size to modality of sensation. The manuscript ponders on the central paths of the afferent impulses from skin that arouse sensation and studies related to the mechanism of common sensibility, including materials and methods, anatomical and physiological observations, and interpretation of observations. The publication also takes a look at the structures and processes involved in the sensation of itch and the pathophysiology of itch sensation. The selection is a dependable reference for readers interested in the biology of skin.
List of Contributors
Introduction
Chapter 1 The Pattern of Cutaneous Innervation of the Human Hand, Foot and Breast
I. Introduction
II. Methods of Study
III. Observations
A. The Pattern of Cutaneous Innervation of the Hand
B. The Pattern of Cutaneous Innervation of the Human Foot
C. The Pattern of Cutaneous Innervation of the Human Breast
D. The Pattern of Innervation of the Deeper Tissues
IV. Discussion
V. Summary
VI. References
Chapter II Similarities in Cutaneous Nerve End-Organs
I. Introduction
II. The Histochemical Reactions
III. The Function of End-organs
IV. Comment
V. References
Chapter III The Autonomic Innervation of the Skin
I. General Discussion
II. References
Chapter IV Cholinesterases in the Cutaneous Nerves of Man
I. Introduction
II. Cholinesterase in Nerve Endings
III. The Nerves around the Cutaneous Glands
IV. The Nerves around Hair Follicles
V. Comments
VI. Summary
VII. References
Chapter V The Relation of Nerve Fiber Size to Modality of Sensation
I. Introduction
II. References
Chapter VI The Central Paths of the Afferent Impulses from Skin Which Arouse Sensation
I. Introduction
A. The Separation of Sensory Paths into Central Tracts
B. The Central Projections of the Sensory Systems
C. The Problem of Pain and Temperature Reception
D. Comparison of Somaesthetic and Visual Sensory Systems
E. The Large-Fiber System in the Mammalian Cortex
F. The Development of the Cortex as a Sensory Apparatus
G. Convergence of the Sensory Paths
II. References
Chapter VII Studies Related to the Mechanism of Common Sensibility
I. Introduction
II. Material and Methods
A. Anatomical
B. Physiological
III. Anatomical Observations
A. The Topography of the Ciliary Nerve Bundles
B. Fiber Content of "Long" and "Short" Ciliary Nerve Bundles
C. Number of Nerve Fibers Supplying the Cornea Counted at the Limbus
D. Number of Nerve Fibers 6ì and larger in "Long" and "Mixed" Ciliary Nerve Bundles
E. The Surface Areas of Cornea Served by the Various Types of Ciliary Nerve Bundles
IV. Physiological Observations
A. Activity Evoked in Whole "Long" Ciliary Nerve Bundles by the Application of Various Stimuli to the Cornea
B. Activity Evoked in Teased Fractions of Fine "Long" Ciliary Nerve Bundles by Brushing and Heat Transfer
C. Activity Evoked in Teased Fractions of Fine "Long" Ciliary Nerve Bundles by Electrical Stimulation of the Cornea
D. Control Experiments
E. The Distribution, in the Cornea, of the Terminals Served by Nerve Fibers of Different Diameters
F. Anomalous Observations
V. Interpretation of Observations
VI. Discussion
VII. Acknowledgments
VIII. References
Chapter VIII Structures and Processes Involved in the Sensation of Itch
I. Introduction
II. Demonstration of Lowered Pain Threshold in Areas of Itching
III. The Qualities of Cutaneous Pain and Itch
A. Demonstration of Itching Sensation with a Burning Quality
B. Demonstration of an Itching Sensation with Pricking Quality
IV. Demonstration that Itch can be Abolished by Painful Pin Pricks within the Same Dermatome
V. Demonstration that a Zone of Secondary Hyperalgesia Is "Anti-Pruritic"
VI. Demonstration that Vasodilatation Is Accompanied by Lowered Pain Threshold and Spontaneous Itching
VII. Demonstration of Heightened Vulnerability in Zones of Vasodilatation
VIII. Demonstration of a Bradykinin-type Agent in Subcutaneous Perfusate Collected from Zones of Lowered Pain Threshold and Spontaneous Itching
IX. Comment
X. Demonstration that Activation of Sweat Glands Is Not a Required Step in Bradykinin Formation during Vasodilatation
XI. Demonstration that Central Nervous System Activity at the Highest Level Is Implicated in the Activation of Proteolytic Enzymes in the Periphery
XII. Comment
XIII. Summary and Conclusions
XIV. References
Chapter IX Pathophysiology of Itch Sensation
I. Pain and Itch
II. Itch and Protopathic Pain
III. Physiological and Pathological Pruritus
IV. Itching Hyperexcitability
A. Chronic Perianal Eczema with Reddening and Patchy Epidermal Thickening
B. Chronic Eczema of the Right Hand with Diffuse Reddening, Papules, Blisters, Irregularly Arranged Adherent Scales
V. Spontaneous Itch and Anatomical Changes
VI. The Site of Itch Terminals
VII. Vasomotor Fibers
VIII. Psychic Factors
IX. Summary
X. References
Subject Index
- Edition: 1
- Published: January 1, 1960
- Imprint: Pergamon
- No. of pages: 216
- Language: English
- Hardback ISBN: 9780080093857
- Paperback ISBN: 9781483233345
- eBook ISBN: 9781483280882
WM
William Montagna
Affiliations and expertise
Oregon Regional Primate Research Center, Beaverton, U.S.A.Read Cutaneous Innervation on ScienceDirect