
Cartilage V1
Structure, Function, and Biochemistry
- 1st Edition - April 28, 1983
- Imprint: Academic Press
- Author: Brian K. Hall
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 1 1 9 6 0 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 3 9 5 8 - 8
Cartilage, Volume 1: Structure, Function, and Biochemistry provides an in-depth treatment of cartilage structure, function, and biochemistry. Topics range from vertebrate and… Read more

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Request a sales quoteCartilage, Volume 1: Structure, Function, and Biochemistry provides an in-depth treatment of cartilage structure, function, and biochemistry. Topics range from vertebrate and invertebrate cartilages to chondroblasts and chondrocytes, along with the use of transmission electron microscopy and scanning electron microscopy to examine cartilage. The collagens and cell kinetics of cartilage are also discussed. Comprised of 12 chapters, this volume begins with an overview of the diversity of cartilage in vertebrates and invertebrates in terms of structure, function, and evolution. The principal common attributes of vertebrate cartilages as well as those specific parameters that usefully serve to distinguish between cartilaginous tissues at several phylogenetic levels are discussed. Function and level of function are considered, along with their correlations with the structural attributes of a specific cartilage. Subsequent chapters explore the chondroblasts and chondrocytes of cartilage, particularly how they arise and how they are maintained; the ultrastructure of cartilage; the biochemistry of cartilaginous extracellular matrices; and the kinetic and metabolic properties of cartilage cells. The final chapter analyzes the mechanisms of calcification of cartilage. This book will be of interest to biologists and biochemists.
Contributors
Preface
Contents of Other Volumes
1. Vertebrate Cartilages
1. Introduction
II. Definitions and Classification
III. General Texts
IV. Antiquity of Cartilage and Bone
V. Modulation Hypothesis
VI. Principal Trends of Cartilage Evolution
VII. Epiphyses
VIII. Secondary Cartilage
References
2. Invertebrate Cartilages
I. Introduction and Historical Review
II. Occurrence of Cartilage in Invertebrates: Morphologic and Microscopic Observations
III. Chemistry of Invertebrate Cartilage
IV. The Plant-Like Features of Some Cartilage Tissues
References
3. The Chondroblast and the Chondrocyte
I. Introduction
II. The Chondrocytic Phenotype
III. Acquisition of the Chondrocytic Phenotype
IV. Precartilaginous Mesenchymal Cells
V. Regulation of Cartilage Differentiation
VI. Maintenance of the Chondrocyte Phenotype
References
4. Transmission Electron Microscopy of Cartilage
I. Introduction
II. Cartilage Matrix
III. Cells in Cartilage
References
5. Scanning Electron Microscopy of Cartilage
I. Introduction
II. Examination of Cartilage in the SEM: Previous Studies and Techniques
III. Present Study
References
6. Cell Kinetics of Cartilage
I. Introduction
II. Basic Concepts
III. Cell Kinetics and Overall Bone Growth
IV. The Problems and Precision of Cell Kinetics
V. Techniques in Cell Kinetics
VI. Application of Cell Kinetics
VII. Computer Modeling
VIII. Cell Kinetics and Theories of Growth Control
IX. Conclusions
References
7. Collagens of Cartilage
I. Introduction
II. Collagens in Different Types of Cartilage
III. Chemistry of Cartilage Collagens
IV. Biosynthesis of Cartilage Collagen
V. Synthesis of Cartilage Collagen in Vitro
VI. Immunohistochemical Localization of Type II Collagen in Tissues and Cell Cultures
VII. Degradation, Regeneration, and Autoimmunity of Collagen in Cartilage Diseases
References
8. Glycosaminoglycans of Cartilage
I. Introduction and Terminology
II. Biosynthesis and Regulation of Synthesis
III. Deposition and Degradation
IV. In Vitro Versus in Vivo Studies
V. Interactions with Other Molecules
VI. Abnormalities of Glycosaminoglycans and Proteoglycans
VII. Tissue-Specific Proteoglycans
VIII. Role of Proteoglycans in Development and Differentiation
References
9. Metabolism of Cartilage
I. Introduction
II. Respiration and Glycolysis
III. Biosynthesis of Macromolecules
IV. Degradation of Macromolecules
V. Turnover of Macromolecules
VI. Regulation of Cartilage Metabolism
References
10. Vascularity of Cartilage
I. Introduction
II. The Anatomy of the Cartilage Blood Supply
III. Mechanisms of the Resistance of Cartilage Matrices to Vascular Invasion
IV. The Resistance of Cartilage to Tumor Cell Invasion
V. Conclusions
References
11. Biomechanics of Cartilage and its Response to Biomechanical Stimuli
I. Introduction
II. Mechanical Behavior of Materials
III. Cartilage Composition and Structure in Relation to Mechanical Properties
IV. Cartilage Mechanical Properties
V. Effects of Degeneration on Cartilage Mechanical Properties
VI. Concluding Remarks
References
12. Calcification of Cartilage
I. Introduction
II. Process of Calcification
III. Factors Involved in Initiating Calcification
IV. Epiphyseal Cartilage Calcification
V. Discovery and Role of Matrix Vesicles
VI. Pathological Calcification of Cartilage
References
Index
- Edition: 1
- Published: April 28, 1983
- No. of pages (eBook): 400
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780124119604
- eBook ISBN: 9780323139588
BH
Brian K. Hall
I have been interested in and studying skeletal tissues since my undergraduate days in Australia in the 1960s. Those early studies on the development of secondary cartilage in embryonic birds, first published in 1967, have come full circle with the discovery of secondary cartilage in dinosaurs12. Bird watching really is flying reptile watching. Skeletal tissue development and evolution, the embryonic origins of skeletal tissues (especially those that arise from neural crest cells), and integrating development and evolution in what is now known as evo-devo have been my primary preoccupations over the past 50+ years.
Affiliations and expertise
Department of Biology, Dalhousie University, Halifax NS CanadaRead Cartilage V1 on ScienceDirect