Books in Pharmaceutical sciences

451-460 of 465 results in All results

Advances in Drug Research

1st Edition
Volume 26
September 5, 1995
Bernard Testa + 1 more
English
Hardback
9 7 8 - 0 - 1 2 - 0 1 3 3 2 6 - 0
eBook
9 7 8 - 0 - 0 8 - 0 5 2 6 6 9 - 0

Volume 26 continues the trend of shorter, more frequent volumes. With Volume 25, the series gained a new co-editor, Urs Meyer. While retaining the commitment to publish chapters on therapeutic or chemical classes and on general topics or concepts, the series' coverage has expanded to include methodological chapters, and new areas of recognized or potential significance to drug research, especially in molecular pharmacology.

The Chemistry and Pharmacology of Taxol® and its Derivatives

1st Edition
Volume 22
June 16, 1995
H. Timmerman
V. Farina
English
eBook
9 7 8 - 0 - 0 8 - 0 5 4 4 9 9 - 1

Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and metastatic breast cancer) may soon be expanded since the drug is showing activity against lung and head-and-neck cancers.The book opens with a review of the naturally occurring taxoids, a chapter which is not a comprehensive list of all taxoids isolated to date, but attempts a systematic approact to describing the different classes of taxoids, with particular reference to all skeletal types and the various functionality patterns. Biosynthetic studies are also discussed, as well as some of the basic chemistry and common functionalities of taxoidic skeleton. Structural identification of taxoids, mostly by spectroscopic means; the formulation of taxanes; the metabolism and pharmacokinetics of Taxol® are also discussed, as are the chemistry of taxanes in relation to SAR studies; SAR aspects of the phenylisoserine side chain; and the mode of action of the taxanes and the mechanisms of resistance.The book is therefore written for medical chemists, in order to stimulate further research in this area and to provide the reader with the necessary background information to start a research program in the area.

Anesthesia and Cardiovascular Disease

1st Edition
Volume 31
November 21, 1994
Zeljko J. Bosnjak + 1 more
English
eBook
9 7 8 - 0 - 0 8 - 0 8 8 0 2 6 - 6

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Volume 31 deals with the mechanisms of anesthetic actions under normal conditions as well as pathophysiologic states.

Anesthesia and Cardiovascular Disease

1st Edition
Volume 31
November 21, 1994
J. Thomas August + 3 more
English
Hardback
9 7 8 - 0 - 1 2 - 0 3 2 9 3 2 - 8

Biochemistry of Redox Reactions

1st Edition
October 25, 1994
Bernard Testa + 1 more
English
Hardback
9 7 8 - 0 - 1 2 - 6 8 5 3 9 1 - 9

Surpassing the 1976 book by Testa and Jenner, Drug Metabolism: Chemical and Biochemical Aspects (Dekker), this informative, up-to-date text includes the following features, unavailable elsewhere: First in a set of books to provide a comprehensive coverage of drug metabolism; Opening chapter provides a general introduction to the complete set of books; Other chapters cover reaction mechanisms, catalytic cycles, regio- and stereoselectivities, types of substrates, reactivity of intermediates, and drug-enzyme interactions; Extensive detailed diagrams of reaction pathways and chemical structures

Analytical Profiles of Drug Substances and Excipients

1st Edition
Volume 23
July 22, 1994
Harry G. Brittain
English
eBook
9 7 8 - 0 - 0 8 - 0 8 6 1 1 8 - 0

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the AmericanAssociation of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.

Advances in Pharmacology

1st Edition
Volume 28
May 19, 1994
J. Thomas August + 3 more
English
Hardback
9 7 8 - 0 - 1 2 - 0 3 2 9 2 8 - 1
eBook
9 7 8 - 0 - 0 8 - 0 5 8 1 1 9 - 4

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

Analytical Profiles of Drug Substances and Excipients

1st Edition
Volume 22
October 1, 1993
Harry G. Brittain
English
eBook
9 7 8 - 0 - 0 8 - 0 8 6 1 1 7 - 3

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The series has recently been expanded to include profiles of excipient materials.

The Organic Chemistry of Drug Design and Drug Action

1st Edition
March 27, 1992
Richard B. Silverman
English
eBook
9 7 8 - 0 - 0 8 - 0 5 7 1 2 3 - 2

This is a new approach to the teaching of medicinal chemistry. The knowledge of the physical organic chemical basis of drug design and drug action allows the reader to extrapolate to the many related classes of drugs described in standard medicinal chemistry texts. Students gain a solid foundation to base future research endeavors upon: drugs not yet developed are thus covered!

Process Chromatography

1st Edition
October 2, 1991
Gail K. Sofer + 1 more
English
eBook
9 7 8 - 1 - 4 8 3 2 - 8 9 1 7 - 5

Research and development into biological products for therapeutic use has increased dramatically over the last 10 years. With this, strict regulatory requirements have been imposed by authorities such as the U.S. Food & Drug Administration, so that today validation has become a key issue in the biopharmaceutical industry.This concise book addresses validation issues in the chromatography of biotherapeutics. It covers process design, qualification and validation, including an overview of analytical techniques commonly used in the validation of processes. A concluding section comments on product changeover and presents four case studies.