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The Role of the Mitochondria in Neural Degeneration

  • 1st Edition - January 1, 2025
  • Author: Xin Qi
  • Language: English
  • Hardback ISBN:
    9 7 8 - 0 - 4 4 3 - 2 1 7 5 7 - 9
  • eBook ISBN:
    9 7 8 - 0 - 4 4 3 - 2 1 7 5 6 - 2

The Role of the Mitochondria in Neural Degeneration examines the significance of mitochondria and their impairment in the development of neurodegenerative condition… Read more

The Role of the Mitochondria in Neural Degeneration

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The Role of the Mitochondria in Neural Degeneration examines the significance of mitochondria and their impairment in the development of neurodegenerative conditions.

The book opens with an introduction to mitochondria and their significance in neuronal function before exploring the cause and effect of mitochondrial impairment. Chapters cover a range of aspects including mitochondrial dynamics in neurodegenerative diseases, mitophagy and autophagy in neuronal degeneration, and mtDNA integrity. Intercellular connection damage and the effect this can have on cellular function is also investigated. Finally the book closes with a section on therapeutic interventions for targeting mitochondria in the treatment of human diseases.

This is a volume in Elsevier’s new series Hot Topics in Physiology, published in association with the International Union of Physiological Sciences (IUPS). It is an ideal reference for cell biologists, investigators in mitochondrial biology, and researchers working with neurodegenerative diseases.