This completely updated work presents a unique source of references describing the cellular, subcellular and molecular mode of action of the main immunosuppressive agents used clinically. The following six agents (or methods) have been considered: azathioprine, corticosteroids, cyclophosphamide, cyclosporine, antilymphocyte antibodies (monoclonal and polyclonal), and total lymphoid mediation.
Experimental and human immunological data is presented in a comprehensive way to show synthetically the mode of action of these agents in patients.
Readers potentially interested in this work include clinical and basic immunologists, nephrologists, rheumotologists, dermatologists, hematologists, transplant surgeons and physicians, internal medicine specialists and clinicians of nearly all disciplines interested in automimmune diseases.