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The Human Research Program for Civilian Spaceflight
- 1st Edition - January 1, 2026
- Editors: Marianne Legato J, Michael Marge, Michael Schmidt A
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 3 4 7 7 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 3 4 7 8 - 8
"The Human Research Program for Civilian Spaceflight" is a collaborative handbook that discusses state of the art techniques for spaceflight, describes the research methodolo… Read more
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Request a sales quote"The Human Research Program for Civilian Spaceflight" is a collaborative handbook that discusses state of the art techniques for spaceflight, describes the research methodology for assessing and improving the capacity of ordinary individuals for fitness to fly in space, identifies their specific vulnerabilities, and prescribes training and treatment to equip them for extraterrestrial thriving. This is a unique and vitally important resource based on an evidence-based program for assessing and optimizing the expeditionary fitness of civilians for space travel and populating human settlements in low Earth orbit, the Moon, Mars, and beyond. This is essential for researchers and scientists, and practitioners in government space programs as well as graduate and post-graduate space medicine certification and diplomate programs aimed at physicians (and other qualified clinicians). Anyone wanting an outline on how to build a human research program for civilians in space will find this a must have resource.
• Describes comprehensive phenotyping to utilize state of the art techniques to assess the behavioral, environmental, molecular, morphological, and physiological analysis of each unique individual who is a candidate for flying in space
• Includes research projects on the specific biomedical risks the Human Research Program entails, i.e.: altered gravity and gravity transitions, environmental exposures, the impact of isolation, confinement, and awareness of the distance from earth, and the dangers of space radiation
• Emphasizes the impact of biological sex/ gender on space medicine research and practice
• Provides a sophisticated and varied system of capabilities and programs to include essential and unique items such as the construction of a human specimen biorepository, human data repository, and space health (and adverse event) reporting systems
• Includes research projects on the specific biomedical risks the Human Research Program entails, i.e.: altered gravity and gravity transitions, environmental exposures, the impact of isolation, confinement, and awareness of the distance from earth, and the dangers of space radiation
• Emphasizes the impact of biological sex/ gender on space medicine research and practice
• Provides a sophisticated and varied system of capabilities and programs to include essential and unique items such as the construction of a human specimen biorepository, human data repository, and space health (and adverse event) reporting systems
A resource for occupational medicine researchers and practitioners that emerges around civilian space travel; government space programs, as it lays out key elements that would benefit government space programs: precision medicine, pharmacogenomics, etc.
Part I. INTRODUCTION Part II. OPERATING PRINCIPLES OF A HUMAN RESEARCH PROGRAM FOR CIVILIAN SPACEFLIGHT 1. Comprehensive Phenotyping 2. Biomedical Risks and Research Priorities 3. Operations and Programs 4. Space Destinations Part III. TRACK 1: COMPREHENSIVE PHENOTYPING 1. Behavioral Phenotyping 2. Environmental Phenotyping 3. Molecular Phenotyping 4. Morphological Phenotyping 5. Physiological Phenotyping Part IV. BIOMEDICAL RISKS AND RESEARCH PRIORITIES 6. Altered Gravity and Gravity Transitions 7. Environmental exposures 8. Isolation, Confinement, and Distance from Earth 9. Space Radiation Part V. OPERATIONS & PROGRAMS 10. Artificial Intelligence and Predictive Modeling 11. Civilian Training 12. Continuing Medical Education 13. Countermeasure Development 14. Ethics and Rights 15. Exercise and Musculoskeletal Loading 16. Food and Nutrition 17. Human Spaceflight Data Repository 18. Human Specimen Biorepository 19. Human System Risk Board for Civilians (HSRB-C) 20. IRB for Civilian Spaceflight (IRB-C) 21. Regenerative Medicine 22. Space Health Reporting System (SHRS) 23. Precision Medicine 24. Preparation and Contingencies 25. Terrestrial Applications of Space Research Part VI: SPACE DESTINATIONS 26. Suborbital 27. Low Earth Orbit (LEO) 28. Medium Earth Orbit (MEO) to High Earth Orbit (HEO) 29. Geosynchronous and Geostationary Orbits (GEO) 30. Cislunar Space (transit, lunar orbit, surface operations) 31. Mars (transit, Mars orbit, surface operations) 32. Beyond Mars, e.g., the Main Asteroid Belt (MAB) APPENDICES REFERENCES
- No. of pages: 200
- Language: English
- Edition: 1
- Published: January 1, 2026
- Imprint: Elsevier
- Paperback ISBN: 9780443334771
- eBook ISBN: 9780443334788
ML
Marianne Legato J
Dr. Marianne Legato, Emerita Professor of Clinical Medicine at Columbia University, is an internationally known academic physician, author, lecturer, and specialist in gender-specific medicine. She is founding member of the International Society for Gender Medicine and the founder and director of The Partnership for Gender-Specific Medicine at Columbia University and its next iteration, The Foundation for Gender-Specific Medicine. She has published extensively on gender and sex specific medicine, both for the scientific community and for the lay public. She is also the founding editor of the Journal Gender Medicine, and the journal Gender and the Genome. In 1992, Dr. Legato won the American Heart Association’s Blakeslee Award for the best book written for the lay public on cardiovascular disease. The third edition of her textbook, Principles of Gender-Specific Medicine and her most recent book, The Plasticity of Sex., both won Prose awards from the American Association of Editors in 2021 and 2022 respectively. She is a practicing internist in New York City and has been listed each year in New York Magazine and Castle Connolly’s lists "Best Doctors" since their inception in 1993.
Affiliations and expertise
Emerita Professor, Clinical Medicine, Columbia University College of Physicians & Surgeons and Adjunct Professor, Medicine at Johns Hopkins Medical SchoolMM
Michael Marge
Vice Chair, IAASS Workshop Planning Committee for the Human Research Program for Civilians in Spaceflight and Space Radiation; Former Chair of the CSF/MITRE Workshop on Creating a Human Research Program for Civilians in Commercial Space (HRP); Editor of the Workshop Summary Report and HRP; Former Scientific and Technical Advisor on Human Space Research, National Institutes of Health, U.S. Department of Health and Human Services and National Aeronautics and Space Administration, and the MITRE Corporation; Research Professor, Department of Physical Medicine and Rehabilitation, State University of New York Upstate Medical University, Syracuse, NY.
Affiliations and expertise
Research Professor, Department of Physical Medicine and Rehabilitation, State University of New York Upstate Medical University, Syracuse, NYMS
Michael Schmidt A
Dr. Michael A Schmidt is the CEO and Chief Scientific Officer of Sovaris Aerospace. He is a leader in precision medicine applied to humans operating in extreme environments on Earth and in space. Dr. Schmidt has three decades of experience working with elite performers in extreme environments including astronauts, military Special Forces, NFL, NBA, Olympic athletes, military aviators, and others. This includes his early research within NASA’s Human Systems Integration Division. Dr. Schmidt is the President of the Human Research Program for Civilian Spaceflight and is the former President of the Life Sciences and Biomedical Engineering Branch (LSBEB) of the Aerospace Medical Association. His molecular work in space is highlighted in a special 2024 issue of Nature entitled, “Space Omics.” His recent innovations include the Astronaut Digital Twin. Dr. Schmidt is the 2019 winner of the Research & Development Innovation Award from the Life Sciences and Biomedical Engineering Branch of the Aerospace Medical Association. He is the 2020 recipient of the Marie Marving Award for Excellence in Aerospace Medicine from the Aerospace Medical Association.
Affiliations and expertise
CEO and Chief Scientific Officer of Sovaris Aerospace, USA; President, Human Research Program for Civilian Spaceflight