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Neurobiology of Type 2 Diabetes
- 1st Edition - June 1, 2026
- Editors: Sandeep Kumar Singh, Shovit Ranjan, Burkhard Poeggeler
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 2 8 4 8 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 2 8 4 9 - 7
The "Neurobiology of Type 2 Diabetes" delves into the intricate interplay between the nervous system and the development, progression, and management of Type 2 Diabetes. This… Read more
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Request a sales quoteThe "Neurobiology of Type 2 Diabetes" delves into the intricate interplay between the nervous system and the development, progression, and management of Type 2 Diabetes. This comprehensive volume explores the often-overlooked neurological aspects of diabetes, offering a unique perspective on the disease. The purpose of this book is to bridge the gap between neuroscience and diabetes research, providing a consolidated resource that elucidates the complex relationship between the brain and metabolic regulation. By synthesizing the latest scientific findings, the book aims to offer researchers, clinicians, and students a deep understanding of how neural pathways influence glucose homeostasis, insulin sensitivity, and the emergence of diabetic complications.
• Discusses the neurobiology of glucose homeostasis and insulin resistance
• Includes neural circuits and neuroendocrine regulation
• Identifies clinical manifestations, diagnostic tools, and management for diabetic neuropathy
• Provides case studies for examples of cases and clinical decisions with outcomes
• Reviews emerging therapeutics for Type 2 diabetes
• Includes neural circuits and neuroendocrine regulation
• Identifies clinical manifestations, diagnostic tools, and management for diabetic neuropathy
• Provides case studies for examples of cases and clinical decisions with outcomes
• Reviews emerging therapeutics for Type 2 diabetes
researchers, clinicians, and graduate students in the fields of neurobiology, endocrinology, and diabetes research
1. Introduction to Neurobiology and Type 2 Diabetes: This chapter provides an overview of the fundamental concepts of neurobiology and its relevance to the development and progression of Type 2 Diabetes. It establishes the groundwork for understanding the intricate relationship between the nervous system and metabolic regulation.
2. Neural Regulation of Glucose Homeostasis: Focusing on the central nervous system, this chapter explores the mechanisms through which neural pathways regulate glucose homeostasis. It delves into the brain's role in influencing insulin sensitivity and the maintenance of blood glucose levels.
3. Neuroinflammation and Insulin Resistance: Examining the connection between neuroinflammation and the development of insulin resistance, this chapter explores the impact of inflammatory processes on neural circuits involved in metabolic regulation. It discusses potential therapeutic targets to mitigate inflammation-associated insulin resistance.
4. Neurological Complications of Type 2 Diabetes: This chapter provides a detailed exploration of the neurological complications associated with Type 2 Diabetes, including neuropathy, cognitive dysfunction, and other related issues. It addresses both the central and peripheral nervous system manifestations of diabetes.
5. Brain-Gut Axis in Metabolic Control: Investigating the bidirectional communication between the brain and the gut, this chapter explores how disruptions in the brain-gut axis contribute to metabolic dysfunction in Type 2 Diabetes. It covers topics such as gut hormones, microbiota, and their impact on neural regulation.
6. Neuroendocrine Regulation of Metabolism: This chapter delves into the complex interactions between the nervous system and endocrine factors in the context of metabolic regulation. It explores the role of neuroendocrine pathways in influencing glucose metabolism and insulin sensitivity.
7. Emerging Therapeutic Approaches in Neurobiology of Type 2 Diabetes: Addressing recent advancements, this chapter discusses emerging therapeutic strategies based on neurobiological insights. It translates research findings into practical applications, providing clinicians and researchers with potential avenues for intervention.
8. Case Studies: Applying Neurobiology in Clinical Practice: Utilizing real-world case studies, this chapter illustrates the practical application of neurobiological concepts in the clinical management of patients with Type 2 Diabetes. It provides insights into diagnosis, treatment, and patient care based on the principles discussed in earlier chapters.
9. Future Directions and Challenges: Looking ahead, this chapter explores future directions in the field of neurobiology and Type 2 Diabetes. It discusses potential areas of research, technological advancements, and the challenges that researchers and clinicians may face in understanding and addressing the neurobiological aspects of diabetes.
10. Conclusion and Summary: The final chapter summarizes key findings and takeaways from the book. It reiterates the importance of neurobiology in understanding Type 2 Diabetes and provides a cohesive conclusion to the comprehensive exploration presented throughout the text.
2. Neural Regulation of Glucose Homeostasis: Focusing on the central nervous system, this chapter explores the mechanisms through which neural pathways regulate glucose homeostasis. It delves into the brain's role in influencing insulin sensitivity and the maintenance of blood glucose levels.
3. Neuroinflammation and Insulin Resistance: Examining the connection between neuroinflammation and the development of insulin resistance, this chapter explores the impact of inflammatory processes on neural circuits involved in metabolic regulation. It discusses potential therapeutic targets to mitigate inflammation-associated insulin resistance.
4. Neurological Complications of Type 2 Diabetes: This chapter provides a detailed exploration of the neurological complications associated with Type 2 Diabetes, including neuropathy, cognitive dysfunction, and other related issues. It addresses both the central and peripheral nervous system manifestations of diabetes.
5. Brain-Gut Axis in Metabolic Control: Investigating the bidirectional communication between the brain and the gut, this chapter explores how disruptions in the brain-gut axis contribute to metabolic dysfunction in Type 2 Diabetes. It covers topics such as gut hormones, microbiota, and their impact on neural regulation.
6. Neuroendocrine Regulation of Metabolism: This chapter delves into the complex interactions between the nervous system and endocrine factors in the context of metabolic regulation. It explores the role of neuroendocrine pathways in influencing glucose metabolism and insulin sensitivity.
7. Emerging Therapeutic Approaches in Neurobiology of Type 2 Diabetes: Addressing recent advancements, this chapter discusses emerging therapeutic strategies based on neurobiological insights. It translates research findings into practical applications, providing clinicians and researchers with potential avenues for intervention.
8. Case Studies: Applying Neurobiology in Clinical Practice: Utilizing real-world case studies, this chapter illustrates the practical application of neurobiological concepts in the clinical management of patients with Type 2 Diabetes. It provides insights into diagnosis, treatment, and patient care based on the principles discussed in earlier chapters.
9. Future Directions and Challenges: Looking ahead, this chapter explores future directions in the field of neurobiology and Type 2 Diabetes. It discusses potential areas of research, technological advancements, and the challenges that researchers and clinicians may face in understanding and addressing the neurobiological aspects of diabetes.
10. Conclusion and Summary: The final chapter summarizes key findings and takeaways from the book. It reiterates the importance of neurobiology in understanding Type 2 Diabetes and provides a cohesive conclusion to the comprehensive exploration presented throughout the text.
- No. of pages: 300
- Language: English
- Edition: 1
- Published: June 1, 2026
- Imprint: Academic Press
- Paperback ISBN: 9780443328480
- eBook ISBN: 9780443328497
SS
Sandeep Kumar Singh
Dr. Singh is the Founder President of Indian Scientific Education and Technology (ISET) Foundation. He is researcher and neuroscientist with a strong background in Biochemistry and Biomedicine. His research interests are in neurodegenerative diseases and has ~9 years of experience. He’s a member of editorial boards of several international journals related to field of neuroscience, the member of several scientific societies. Dr. Singh has been appointed as Bentham Ambassador by Bentham Science Publisher (USA). He is a speaker at several scientific national and international conferences/symposium/workshops in India and abroad.
Affiliations and expertise
Indian Scientific Education and Technology Foundation, Krishna Bhawan, Nilmatha Lucknow, Uttar Pradesh, IndiaSR
Shovit Ranjan
Dr. Shovit Ranjan is Assistant Professor and neuroscientist with a demonstrated history of teaching and research in Zoology, Life Sciences & allied subjects in the colleges and universities. He is skilled in molecular neurobiology, bioinformatics, meta-analysis and various other molecular biology methods. He is strong education professional with a Bachelors and Masters in Zoology from University of Delhi and further Doctor of Philosophy (Life Sciences) focused on Molecular Neurobiology from Central University of Jharkhand. He was selected for presenting his research work on the role of BDNF in Type 2 Diabetes in Federation of European Neuroscience Society (FENS) Regional Meeting, 2017 at Pecs, Hungary and was also awarded with prestigious ICMR Travel Grant award to attend the same. Moreover, he has also qualified JRF/NET, GATE in different subjects, including Life Sciences, Animal Biotechnology & Forensic Sciences. His research expertise is in the areas of Molecular Neurobiology, Type 2 Diabetes, Bioinformatics, Systematic Reviews and Meta-Analysis. He has presented his findings in various national and international conferences and published several research and review articles in different peer-reviewed international journals of repute. He has also published several book chapters in edited books published by reputed publishing house. He has good teaching and research experience in prestigious institutes, including Miranda House, University of Delhi, Delhi. Currently, he has been working as Assistant Professor in University Department of Zoology, Kolhan University, Jharkhand since 2022. He has also worked as organizing committee member and resource person in various workshops, seminars, webinars for undergraduate and postgraduate students.
Affiliations and expertise
Kolhan UniversityBP
Burkhard Poeggeler
Dr. Burkhard Poeggeler is affiliated with the Georg-August-University Göttingen and works primarily on the biochemistry and pharmacology of regeneration by antioxidant protection and trophic prosurvival signaling. His research focusses on bioenergetic agents such as nitric oxide and on redox regulation such as neurovascular coupling. Together with many other distinguished scientists he investigates the unique nootropic, neurotrophic and neuroprotective activity of melatonin and related tryptophan metabolites based on their potent antioxidant, anti-inflammatory antiamyloidogenic effects such as amyloid clearance by the glymphatic system, the connective tissue, the interstitium and the gastrointestinal tract. Based on the exploration of these protective agents, he works on developing new possibilities to extend human health and life span. He is widely published with over 120 PubMed listed publications.
Affiliations and expertise
Department of Biology and Psychology, Georg-August-University Göttingen, Germany