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Elsevier

Books in Life sciences

  • Bioinformatics Essentials II

    From Multi‑omics to AI – Methods, Workflows, and Translational Applications
    • 1st Edition
    • Syed Mudasir Ahmad + 3 more
    • English
    Bioinformatics Essentials II, From Multi‑omics to AI – Methods, Workflows, and Translational Applications offers a comprehensive guide to modern bioinformatics, focusing on best-practice workflows for multi-omics data analysis and AI-assisted discovery. Designed for learners and early-career researchers, it bridges foundational knowledge with cutting-edge applications. The book covers experimental design, sequencing technologies, and core omics workflows including transcriptomics, proteomics, metabolomics, and epigenomics. Advanced chapters explore single-cell and spatial omics, multi-omics integration, AI/ML applications, and environmental bioinformatics.Each chapter includes learning objectives, worked examples, toolbox comparisons, and reproducible code. This resource empowers students, faculty, and applied researchers to confidently analyze complex datasets and translate findings into agriculture, health, and environmental solutions. Its modular structure and companion website enhance usability in both coursework and independent study.

  • Responsible AI in Healthcare

    Navigating the EU AI Act and Global Regulatory Frameworks
    • 1st Edition
    • Miltiadis D. Lytras + 4 more
    • English
    Responsible AI in Healthcare: Navigating the EU AI Act and Global Regulatory Frameworks examines how health systems design, deploy, and oversee AI under evolving legal and ethical mandates. It provides an integrated, practice‑oriented roadmap for compliance and responsible innovation. This book offers the first integrated, comparative treatment of the EU AI Act and global regulatory frameworks for healthcare, translating ethics and law into operational evaluation, governance, and value assessment. Through structured cases, decision tools, and stakeholder methods, it equips researchers and clinicians to design, validate, and deploy AI responsibly—and to keep learning as regulations evolve. Readers gain actionable tools, checklists, and frameworks to operationalize ethical AI, prepare for audits and certifications, and anticipate global convergence (“Brussels Effect”) shaping digital health. The volume serves clinicians, administrators, developers, policy and legal experts seeking rigorous yet accessible guidance.

  • Biosensors and Smart Packaging for Food Products

    A Sustainable Development Approach
    • 1st Edition
    • Gargi Ghoshal + 1 more
    • English
    Biosensors and Smart Packaging for Food Products: A Sustainable Development Approach addresses the emerging field of intelligent food packaging systems which monitor and maintain food quality and safety throughout the supply chain. This book meets the growing research demand for sustainable, biodegradable, and food-grade sensor technologies that provide real-time freshness and spoilage indicators, helping reduce food waste and enhance consumer confidence. The book’s comprehensive chapters cover fundamental principles, recent innovations, and practical applications of active and intelligent packaging systems, including biosensors, RFID technologies, freshness indicators, and wireless sensor integration. Contributors from leading global institutions discuss challenges in commercialization, regulatory frameworks, and case studies on diverse food products such as seafood, meat, and plant-based foods, providing a holistic view of this interdisciplinary field. Biosensors and Smart Packaging for Food Products: A Sustainable Development Approach benefits its readers by delivering critical insights into the design, fabrication, and implementation of smart packaging solutions. It serves as an essential resource for advancing sustainable food packaging technologies that improve food safety, quality assurance, and environmental impact, supporting innovation in academia and the food industry.

  • Health Geography

    Theories, Methods, and Case Studies
    • 1st Edition
    • Peng Jia
    • English
    Health Geography: Theories, Methods, and Case Studies examines the interdisciplinary domain of health geography, systematically integrating geographical science with public health paradigms. The book provides an in-depth analysis of the theoretical foundations, methodological innovations, and practical implications of health geography. Special emphasis is placed on employing geo-spatial technologies, such as Geographic Information Systems (GIS) and remote sensing to enhance disease prevention, health risk assessments, and healthcare resource allocation.By fostering an integrative dialogue among geography, epidemiology, and advanced technological approaches, the book addresses contemporary public health challenges from local to global scales. The book includes over 50 international case studies addressing infectious and chronic diseases, and health resource allocation.

  • Dietary Fiber

    Extraction, Properties and Modifications for Food Applications
    • 1st Edition
    • Tabli Ghosh + 1 more
    • English
    Dietary Fiber: Extraction, Properties and Modifications for Food Applications is an essential resource for food scientists and researchers seeking to understand the full potential of dietary fiber in the food industry. The book highlights fiber's various sources and critical health benefits, including detailed discussions on extraction techniques, characterization, and functional properties, equipping readers with the knowledge needed to innovate and enhance food formulations. Sections explore advanced topics such as nano and microencapsulation techniques that enhance fiber stability and bioavailability and the role of dietary fiber in gut health, microbiome modulation, and broader health implications.As the demand for healthier, functional foods grow, this book addresses the challenges of modifying dietary fiber to improve its solubility, viscosity, and stability through an array of physical, biological, chemical, and alternative methods. Readers will walk away with the knowledge needed to tailor dietary fiber for specific applications in functional food products and precision nutrition for better health outcomes.

  • Human Reproduction

    From basics to Biotechnology
    • 1st Edition
    • Marc yeste
    • English
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

  • Fermented Foods in Health and Disease Prevention

    • 2nd Edition
    • Juana Frías + 2 more
    • English
    Fermented Foods in Health and Disease Prevention, Second Edition examines the significance of fermented foods to public health. The book presents the latest scientific evidence, showing the health-promoting components produced upon fermentation from a diversity of food matrices. The content includes the definition and characterization of traditional and innovative fermented foods, their mechanisms of action, and the evidence for effects on health and disease in humans. Putative health effects associated with direct interactions between the ingested live microorganisms and the host (probiotic effect), or indirectly, through ingestion of microbial metabolites and products of fermentation (biogenic effect) are discussed.This book will provide the food industry with new insights on the development of value-added fermentation, while also presenting nutritionists and dieticians with a useful resource to help them develop strategies to assist in the prevention of disease or to slow its onset and severity.

  • Primer on Cerebrovascular Research

    • 1st Edition
    • Dong-Eog Kim + 3 more
    • English
    Primer on Cerebrovascular Research provides both clinical and basic cerebrovascular knowledge that is required for physicians, vascular researchers, biomedical students, and trainees to understand or conduct evidence-based clinical practice and cutting-edge experimental research. This book outlines how to a design experimental cerebrovascular research in the context of clinical relevance, conduct the study using proper methods, analyze the data accurately, and make conclusions in an unbiased and statistically correct way. Chapters will include representative examples and experimental protocols.

  • Insect Proteins as Sustainable Food Ingredients

    Nutrition, Processing and Consumer Acceptance
    • 1st Edition
    • Ronghai He
    • English
    In the quest for sustainable food solutions alternative to traditional proteins, insects are emerging as a compelling option. Insect Proteins as Sustainable Food Ingredients: Nutrition, Processing and Consumer Acceptance, explores the nutritional composition of various insect species from around the world such as the black soldier fly, cricket, mealworm and silkworm, and sheds light on their high protein, low-carbon, low emission, sustainable environmental benefits while providing insight into nutrition and health. With consumers more likely to eat processed insect products rather than whole body insects, Insect Proteins as Sustainable Food Ingredients: Nutrition, Processing and Consumer Acceptance, examines insect protein extract as a raw materials and how it can significantly reduce consumers’ negative perception of insects as a food source. Experts in the filed introduce readers to the production and processing of insect protein flours, concentrates, isolates and hydrolysates and highlight the defatting, grinding, purification, drying and extraction technologies for insect proteins to be used for product innovation. Also addressed are flavor and sensory properties and ways to measure consumer acceptance of insect-based products. The book concludes by reviewing potential safety and allergy concerns and provides suggestions on how to establish a food safety regulatory framework.

  • Plant Powered Probiotics

    Exploring Science and Health Behind Non-Dairy Fermented Beverages
    • 1st Edition
    • Pintu Choudhary + 2 more
    • English
    Plant Powered Probiotics: Exploring Science and Health Behind Non-Dairy Fermented Beverages guides readers through the scientific aspects of fermentation, including detailing microbial roles, health benefits, and quality control. The book compares health advantages to other sources while emphasizing gut health and the importance of pro-and prebiotics for a healthy microbiome. Precision fermentation, strain selection, and optimized production processes are addressed, along with the safety of agro-waste of some common plant-based ingredients. The book concludes with the next generation and emerging trends in non-dairy probiotic beverage formulations.As the demand for foods containing probiotics coupled with an increased desire for dairy alternatives has opened the door for the creation of functional non-dairy beverages that have proven track records for gut and immune health, this book highlights fermentation origins, processes, and novel plant-based ingredients while also exploring health effects and digestive benefits.

  • Supercritical Fluid Technology for Food Processing

    Fundamentals and Applications
    • 1st Edition
    • Julian Martínez + 2 more
    • English
    Supercritical Fluid Technology for Food Processing: Fundamentals and Applications aims to bring a didactic approach to supercritical fluid technologies, considering the specific aspects of their use in food processing, and including issues that must be considered in a food industrial plant. The book's chapters cover fundamentals and then move through extraction, separation, adsorption, impregnation, drying, physical processing, particle formation, coprecipitation, reaction, and enzyme and microorganism inactivation. It concludes with a chapter on current practice and future challenges, as well as a look at project formulation for developing new food products.Supercritic... fluids have gained increasing attention in the scientific community and industries where their application can lead to valuable products by means of green and sustainable processes. Food processing is one of the greatest application fields of supercritical technology, which can help produce new and natural ingredients. It is increasingly applied by research groups in universities, including food engineering schools.

  • Toxoplasma Gondii

    The Model Apicomplexan - Perspectives and Methods
    • 4th Edition
    • Louis M. Weiss + 1 more
    • English
    Toxoplasma Gondii: The Model Apicomplexan - Perspectives and Methods, Fourth Edition offers a comprehensive approach and balance between historical research, new developments, and innovative approaches to Toxoplasma gondii research. Completely updated and revised, the new Edition aims to provide a better understanding of the structure, genetic diversity, and population biology of T. gondii. The book details the immunology, molecular, and cellular biology of Toxoplasma gondii combined with new molecular techniques, methods, and resources for working with this pathogen. It also offers the latest information concerning epidemiology, diagnosis, treatment, and prevention of toxoplasmosis.With contributions from leading experts in the field, this is an essential one-stop resource for a wide range of researchers, scientists, and clinicians engaged in the study of T. gondii and toxoplasmosis.

  • Molecular Markers and High-throughput Screening

    Bridging Laboratory Discoveries with Clinical Applications
    • 1st Edition
    • Rajesh Singh Pawar + 1 more
    • English
    Molecular Markers and High-throughput Screening: Bridging Laboratory Discoveries with Clinical Applications is a pivotal resource revolutionizing biomedical research and pharmaceutical innovation. This comprehensive reference details cutting-edge methodologies for identifying, analyzing, and utilizing molecular markers through advanced imaging techniques. By focusing on high-throughput strategies, the book offers pathways to faster, more accurate, and scalable research outcomes, bridging the knowledge gap in this rapidly evolving field. Each chapter begins with core concepts, followed by representative case studies that illustrate practical applications. Discussions of limitations and strategies for addressing them ensure a balanced view, preparing readers for real-world applications.Practic... insights and real-world case studies facilitate the understanding and application of High-Throughput Screening (HTS) and In Vitro-In Vivo Correlation (IVIVC) in various contexts, aiding researchers in accelerating their research processes and clinicians in translating research into practice for disease diagnosis and treatment. This essential resource is designed to support the next generation of advancements in precision medicine and targeted therapeutics.

  • AI and Global Health

    Unlocking Transformative Potential
    • 1st Edition
    • Adil Haider
    • English
    AI and Global Health: Unlocking Transformative Potential provides a roadmap for practitioners to apply and leverage artificial intelligence to strengthen health systems using the World Health Organization's health systems approach. The book's combination of case studies and secondary research inspires the possibility of what can happen using AI in healthcare, ensuring the use of robust, scientific evidence to draw conclusions. Additionally, readers will learn from others in settings where AI has been a tool for change, providing healthcare practitioners and policymakers with what they need to think through how it can be applied in resource limited settings.The book provides a strong call to action for policymakers and healthcare leaders of governments, international organizations, and healthcare institutions to take the lead in AI implementation as a key lever for advancing global health goals through a systems approach. As AI is a rapidly evolving field with significant investment made in this industry in recent years from government and the private sector, this book articulates how this growth can be harnessed for countries that need a different approach to addressing global health problems.

  • Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine

    • 1st Edition
    • Anthony Chang + 1 more
    • English
    Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. This book vastly improves the speed of adoption of AI in pediatric and neonatal healthcare by providing a framework of AI deployment in children and healthcare. In addition to a large section on the principles and theories of artificial intelligence as well as its application in a number of pediatric subspecialties, the book will have about 50 commentaries that all have the same structure The book is presented in a systematic manner for all clinicians to understand the in-depth thinking of the leaders in the pediatric AI domain from an international perspective. Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. It also offers a framework for success in planning, deployment, implementation, and evaluation of AI models in healthcare. In addition, current state of the art of pediatric subspecialties will be presented with future directions to guide the pediatric and neonatal clinicians. Finally, a colorful collection of commentaries by leaders of AI use in children’s health is inserted throughout the book.

  • Smart Coldwater Precision Aquaculture

    AI and Eco-Friendly Strategies for Fish Health
    • 1st Edition
    • S. Rehan Ahmad + 2 more
    • English
    Smart Coldwater Precision Aquaculture: AI and Eco-Friendly Strategies for Fish Health addresses the growing need for innovative solutions in coldwater aquaculture. As demand increases for species like salmon and trout, challenges such as disease management, environmental sustainability, and climate impacts require advanced, precision-based approaches. This book fills a critical gap by combining artificial intelligence with eco-friendly practices tailored specifically for coldwater environments. The contents cover foundational concepts of precision aquaculture and AI integration, followed by detailed chapters on machine learning applications, big data analytics, IoT sensors, and green nanotechnology. Sustainable strategies including probiotics, phytochemicals, and integrated multi-trophic aquaculture are explored. The volume also examines translational applications such as climate resilience, blockchain for data security, and policy frameworks. The comprehensive table of contents reflects a multidisciplinary approach involving global experts. Smart Precision Aquaculture benefits researchers, fish health specialists, technology developers, and managers by providing actionable guidance on AI-powered fish health management and sustainable farming. It equips professionals with cutting-edge knowledge to enhance productivity while minimizing environmental impacts. This reference supports the advancement of coldwater aquaculture toward a resilient and responsible future.

  • Nutritional Epigenetics

    Food-Derived microRNAs in Health and Disease
    • 1st Edition
    • Shariful Islam + 3 more
    • English
    Nutritional Epigenetics: Food-Derived microRNAs in Health and Disease offers perspective on the role of dietary microRNAs as pivotal epigenetic regulators influencing health trajectories and disease susceptibility. The book brings together current research on the bioavailability and molecular mechanisms by which plant and food-derived microRNAs modulate gene expression, including their crosstalk with DNA methylation, histone modifications, and gut microbiota. Detailed food-specific chapters examine the epigenetic impact of key dietary sources such as Brassicaceae (crucifers), rice, milk, and fermented products, highlighting their transgenerational and life-stage effects. Practical insights into food processing, culinary traditions, and the design of microRNA-fortified products bridge the gap between bench science and real-world applications. Nutritional Epigenetics equips researchers, clinicians, and industry innovators with a resource that advances the understanding of microRNA-mediated nutritional epigenomics, while guiding the development and safety assessment of microRNA-enhanced functional foods. By integrating molecular biology with population-level evidence and translational strategies, this text fosters the development of novel dietary interventions aimed at optimizing health across the lifespan and mitigating chronic disease risk.

  • GANs in Medical Diagnostics and Classification

    • 1st Edition
    • Abhishek Kumar + 1 more
    • English
    GANs in Medical Diagnostics and Classification explores the role of Generative Adversarial Networks (GANs) in addressing underdiagnosed and overlooked health challenges. The book bridges cutting-edge AI research with real-world medical applications, presenting interdisciplinary insights into how GANs enhance diagnostics, treatment precision, and disease surveillance across domains such as antimicrobial resistance, rare genetic disorders, and environmental health risks. It also examines ethical, policy, and accessibility dimensions of AI in healthcare. By combining technical depth with practical case studies, this volume equips medical researchers, AI engineers, and healthcare professionals with actionable knowledge to tackle silent epidemics using GAN-based tools.

  • Microbiome and Tumorigenesis in Different Cancers

    • 1st Edition
    • Sanjana Mehrotra + 1 more
    • English
    Microbiome and Tumorigenesis in Different Cancers delves into the intricate relationship between the human microbiome and various health conditions, with a particular focus on cancer. It is divided into five parts, each addressing a critical aspect of microbiome research and its implications for health and disease. In 4 parts, the book provides a foundational understanding of the human microbiome, examines the dual role of the microbiome in cancer development, discusses the role of dysbiosis in gastrointestinal, skin, oral, lung, genitourinary, and hematological malignancies, and gives an overview of the methodologies used to study the microbiome.The final part explores the emerging field of pharmacomicrobiomics... focusing on the interaction between the microbiome and cancer therapies. This book serves as a valuable resource for researchers, clinicians, and students interested in understanding the complex interplay between the microbiome and cancer, offering insights into potential therapeutic strategies and future directions in microbiome research.

  • Nanocarrier-Based Immunotherapy

    Emerging Frontiers in Cancer
    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Nanocarrier-Based Immunotherapy: Emerging Frontiers in Cancer explores innovative nanotechnology approaches to enhance cancer immunotherapy. This comprehensive volume addresses the design, mechanisms, and clinical potential of nanocarriers such as polymeric nanoparticles, liposomes, dendrimers, exosomes, and inorganic nanomaterials in modulating immune responses against tumors. The book provides in-depth coverage of foundational principles, recent advancements, and translational strategies. In addition, it discusses how nanocarriers improve targeted delivery, overcome tumor immune evasion, and enable combination therapies.Chapters highlight cutting-edge topics like AI integration, safety profiles, and regulatory considerations, offering a multidisciplinary perspective. Designed for an academic audience, this resource facilitates understanding of nanomedicine’s role in cancer treatment. It equips researchers, clinicians, and students with scientific insights, novel strategies, and practical solutions to accelerate the development of next-generation immunotherapies.

  • Smart Approaches for Cancer Diagnosis, Therapy, and its Associated Challenges

    • 1st Edition
    • Paul A. Millner + 2 more
    • English
    Smart Approaches for Cancer Diagnosis, Therapy, and its Associated Challenges presents a comprehensive exploration of cutting-edge technologies transforming cancer care. This edited volume bridges foundational science with clinical relevance, offering insights into theranostics, nanomedicine, and molecular therapeutics. The book delves into advanced diagnostic tools such as biosensors and theranostic nanoparticles, and therapeutic innovations including peptide-drug conjugates, epigenetic modulation, and nucleic acid-based treatments. It addresses key challenges in glioblastoma, pediatric brain tumors, and drug-resistant cancers, while highlighting translational strategies that integrate diagnostics and therapy. Academics benefit from a multidisciplinary reference that supports research, fosters innovation, and enhances understanding of emerging cancer therapies. It equips researchers with the latest developments to advance precision medicine and improve patient outcomes.

  • Microbiome Stimulants for Crops

    Mechanisms and Applications
    • 2nd Edition
    • James F. White + 1 more
    • English
    Fully revised and updated, Microbiome Stimulants for Crops: Mechanisms and Applications, Second edition continues to provide the latest developments in the real-world development and application of these crop management alternatives in a cost-effective, yield protecting way. Utilizing the plant microbiome as a safe crop management alternative or supplement to chemical fertilizers and other agrochemicals may offer more sustainably produced crops at reduced cost with less environmental degradation. Interest in the approach has led to continuing growth and development of an industry based on applications of microbes in agriculture, with many companies developing products that involve microbes, or biostimulants that affect the plant microbiome. As with the first edition, this book fills the need for comprehensive insights into the potential of this approach, and the new edition includes new chapters as well as updates to existing chapters to ensure that the latest scientific insights are included. It continues to provide a single volume resource designed to address questions of research, development and application.Microbio... Stimulants for Crops supports the field by providing information regarding mechanisms and practical information needed to support the growing microbial inoculant and biostimulant industry, and further to focus scientific research toward areas where more investigation is needed.

  • Rhythmic Regulation in Neuroscience and Clinical Practice

    • 1st Edition
    • Barbara Minton + 2 more
    • English
    Rhythm and Entrainment in Neuromodulation covers cutting-edge and up-to-date information on currently available rhythm-related treatment procedures, as well as the interplay between music and cognition. The book contains contributions from leading experts in the across several fields, exploring the ways in which rhythmic stimulation serves as a powerful neuromodulator, enhancing cognitive function and promoting healing. Best suited for clinicians and researchers interested in neuromodulation, this volume offers profound insights into how rhythm shapes our cognition, influences our well-being, and paves the way for innovative therapeutic practices.

  • Advances in Agronomy

    • 1st Edition
    • Volume 201
    • English
    Advances in Agronomy, Volume 201, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Morbidity Prevention in Aging

    The Role of Salutogenesis Amidst Crises
    • 1st Edition
    • Nestor Asiamah + 3 more
    • English
    Morbidity Prevention in Aging: The Role of Salutogenesis Amidst Crises addresses the urgent need to rethink disease prevention strategies for an aging population. The book begins by exploring how age-friendly environments support health-seeking behaviors. The next section focuses on developing personal skills such as resilience and self-efficacy for maintaining health during crises. Section III examines the reorientation of health services to support preventive care, including community care and diet promotion, while Section IV addresses the creation of policies that facilitate health-promoting interventions and integrate prevention strategies. Community engagement and empowerment in promoting health is emphasized in the fifth section.The book concludes by providing a framework for understanding disease prevention amidst crises, focusing on diverse racial, cultural, and socioeconomic experiences and ensuring equitable opportunities for lifelong disease prevention. This groundbreaking book emphasizes a salutogenic approach that focuses on factors promoting health rather than merely treating diseases. It provides a comprehensive framework for understanding how to maintain health and prevent diseases across the lifespan, even amidst challenges such as wars, climate change, and industrial hazards.

  • Animal Cognition

    Fundamentals, Models, and Therapeutic Advances
    • 1st Edition
    • Shampa Ghosh + 3 more
    • English
    Animal Cognition: Fundamentals, Models, and Therapeutic Advances provides a comprehensive overview of cognitive processes in various animal species, spanning fundamental concepts, species-specific studies, and therapeutic applications. Sections cover the foundation of animal cognition, including definitions, key concepts, and an overview of cognitive abilities, such as memory, problem-solving, and learning, delve deeper into the cognitive processes in mammals, birds, and marine animals, and more, and review the latest technological advancements in studying cognition, such as neuroimaging, machine learning, and virtual reality. With a multidisciplinary approach, this volume highlights current research while identifying gaps for future exploration, and will be of interest to researchers involved in animal cognition and behavioral neuroscience.

  • Artificial Intelligence in Immunoengineering

    Methods, Models, and Translational Applications
    • 1st Edition
    • Steven Zanganeh + 1 more
    • English
    Artificial Intelligence in Immunoengineering: Methods, Models, and Translational Applications examines how AI reshapes immunoengineering to design immune-modulating biomaterials, imaging systems, and diagnostic tools. The book presents an integrated view of data-driven approaches that accelerate discovery and translation in biomedicine. It surveys biological data from single-cell to spatial omics and proteogenomics and offers practical machine learning frameworks, generative and mechanistic models, and multimodal integration strategies. Sections address bench-to-bedside translation, validation pipelines, and regulatory considerations for AI-enabled immunoengineering tools.The book highlights the rapid progress of multidisciplinary research within immunotherapy and immunoengineering. Looking forward, the prospects of immunoengineering appear promising, with further advancements in disease prevention, diagnostics, and treatment on the horizon. Graduate students, academic researchers, clinician-scientists... and computational biologists will gain standardized workflows, mechanism-aware modeling, and reproducible pipelines that advance immunotherapies and diagnostics from concept to clinical impact.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Dissolvable Microneedles (DMNS) For Cancer Diagnosis and Treatment

    • 1st Edition
    • Neetu Talreja + 3 more
    • English
    Dissolvable Microneedles (DMNS) For Cancer Diagnosis and Treatment presents a comprehensive, lab‑to‑clinic overview of dissolving microneedles (DMNs) for cancer diagnosis and therapy, emphasizing painless, minimally invasive delivery and localized treatment. The book details DMN materials, design, and fabrication—includin... AI‑enabled and 3D‑printed approaches—then advances to theranostic applications such as immunotherapy, photodynamic therapy, exosome‑loaded systems, and stimulus‑responsive platforms. Translation topics cover regulation, scale‑up, and CMC, alongside supportive strategies during chemotherapy.Academi... readers gain a structured synthesis of recent advances, practical methods, and clinical outlooks, positioning DMNs as patient‑friendly, cost‑effective tools with significant potential to revolutionize cancer care.

  • The Role of Machine Learning and Artificial Intelligence in Revolutionizing Healthcare

    • 1st Edition
    • Prashant Kesharwani + 1 more
    • English
    Revolutionizing Healthcare: The Role of Machine Learning and Artificial Intelligence describes the complexity of healthcare data that necessitates the expanding use of artificial intelligence (AI). This book offers an explicit accounting of vital aspects on artificial intelligence in healthcare, discussing perspectives of the technologies explored based on findings outlined in highly organized tables, illustrative figures, and flow charts. It brings together novel applications of artificial intelligence in healthcare and helps readers define major gaps in knowledge that can lead to significant scientific discoveries.In addition, the book covers computational drug design, genomic data mining, nanomedicines, medical devices, cosmeceuticals, biosensors, genome counseling, quality control, clinical trials, and cybersecurity. Researchers, students, and scientists will find the book provides foundational and practical knowledge, along with the most advanced AI applications in healthcare.

  • Nanomedicine for Neurological Disorders

    Design, Delivery, and Clinical Perspectives
    • 1st Edition
    • Saman Fatima + 4 more
    • English
    Nanomedicine for Neurological Disorders: Design, Delivery, and Clinical Perspectives addresses the urgent need for innovative solutions in treating complex neurological and neurodegenerative diseases. As the global burden of conditions such as Alzheimer's, Parkinson's, multiple sclerosis, and brain tumors continues to rise, the scientific community faces the critical challenge of safely and effectively delivering therapeutics across the blood-brain barrier. This reference meets the needs of neuroscientists, clinicians, pharmaceutical scientists, and biomedical engineers seeking advanced strategies and translational insights in neuro-nanomedicine. The contents are structured to provide a comprehensive, interdisciplinary exploration of the field. Chapters cover the anatomy and connectivity of the human brain, the global burden and mechanisms of neurological disorders, conventional and nanomedicine-based drug delivery systems, and the intricacies of the blood-brain barrier. Readers will benefit from detailed analyses of nanocarrier engineering, stability, analytical techniques, toxicological safety, regulatory challenges, and artificial intelligence-driven drug design. Real-world case studies, clinical trial data, and future outlooks are presented alongside ethical and patient-centric considerations, ensuring a holistic perspective on the evolving landscape of neuro-nanomedicine. Nanomedicine for Neurological Disorders delivers essential benefits by bridging the gap between laboratory innovation and clinical practice. It equips readers with practical knowledge, foundational advances, and visionary insights to inspire new research directions, inform better decision-making, and accelerate the development of safer, more precise treatments for brain-related disorders. This reference is an indispensable resource for researchers, clinicians, and innovators at the forefront of neurological therapeutics.

  • Oilseeds and Fats

    Trait Improvement, Processing, Properties and Applications
    • 1st Edition
    • Sanju Bala Dhull + 2 more
    • English
    Oilseeds and Fats: Trait Improvement, Processing, Properties and Applications covers recent developments in the areas of oilseeds production practices, breeding, and genetic improvement for sustainable production, with an emphasis on processing technologies and nutrition. The book explores eco-friendly extraction methods, waste reduction techniques, and the potential of using waste by-products for energy production or other applications. Specific sections deal with production, breeding, processing methods, composition, and consumption trends, and then delve into oilseeds and fats origin, composition, and characteristics, as well as the principles and methods involved in processing and refining these resources.Additional sections cover oilseed crops processing, properties, and application, offering insights into the utilization of oilseeds and fats to develop new products that meet consumers' evolving preferences, thus addressing environmental concerns. With increasing awareness of environmental issues and climate change, the book underscores the significance of sustainable practices in the oilseed and fats industry.

  • Methods in Systems Bioinorganic Chemistry

    • 1st Edition
    • Volume 741
    • English
    Methods in Systems Bioinorganic Chemistry, Volume 741 provides understanding of high-level properties involving metals in biology that are founded on molecular or mechanistic level interactions. Currently, there is no established “tool kit” for studying bioinorganic systems, so the methods included in the book span a diverse range of topics and approaches, from imaging to proteomics, from metals-in-mice to mathematical modeling. Specific chapters cover Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-based methods to quantify transition metals in cells and vertebrate models, ICP-MS elemental analysis in tissue samples, and much more.Additional chapters delve into An inductively-coupled-... triple quadrupole method with oxygen for the determination of essential elements and protein concentration, Calculating metal speciation of proteins inside cells, Probing biological copper in the subfemtomolar regime, Using LC-ICP-MS chromatography to detect and characterize Labile Metal Pools, Linking dynamic bioinorganic chemistry processes of toxic metals in the bloodstream to establish their exposure-response relationship in humans, Contextualizing X-ray fluorescent microscopy – high resolution X-rays meet subcellular morphology, Chemoproteomic profiling of transition metal binding sites in bacterial proteomes, Heme Labeling by Proximity (HeLP) to Identify Hemoproteins, and much more.

  • Arginase: Structure, Function, and Therapeutic Targeting

    • 1st Edition
    • Volume 740
    • English
    Arginase: Structure, Function, and Therapeutic Targeting, Volume 740 in the Methods in Enzymology series, provides a comprehensive, methodology-driven perspective on arginase research spanning molecular, biochemical, and translational domains. Chapters in this new release include Expression, Purification, and Structural Characterization of Human and Leishmania Arginase with Comparative Analysis of Structures from the Protein Data Bank, Synthesis of First-Generation Arginase Inhibitors, Computational and Structure-Guided Design of Arginase Inhibitors, Metal Substitution in Arginase: Experimental Approaches to Study Metal-Dependent Catalysis, Therapeutic Arginase Formulations: PEGylation, Stability, and Advanced Delivery Systems, and much more.Additional chapters cover Dual ARG1/ARG2 Inhibition: Experimental and Structural Strategies for Inhibitor Design and Optimization, Synthesis of Second-Generation Arginase Inhibitors, Cryo-EM Workflow and Structural Characterization of Arginase–Antibody Complexes, Development and Validation of an Electrochemical Assay for Arginase Activity, Experimental and Structural Analysis of H. pylori Arginase in Gastric Immune Evasion, Agmatinase and Alternative Arginine Utilization Pathways in Bacteria: Biochemical and Functional Perspectives, Catalytic Diversification of the Arginase Fold: Structural and Mechanistic Insights from DcsB, Beyond Arginase: Structural Biology of the Extended Guanidinase Family, Plant Arginase: Structural and Functional Roles in Nitrogen Metabolism, and much more.

  • Thiamine Pyrophosphate (TPP)-Dependent Enzymes

    • 1st Edition
    • Volume 736
    • English
    Thiamine Pyrophosphate (TPP)-Dependent Enzymes, Volume 736 in the Methods in Enzymology series covers this diverse group of ubiquitous enzymes with timely chapters on Methods for Studying ThDP-dependent Mycobacterial MenDs (SEPHCHC Synthases), Mammalian 2-hydroxyacyl-CoA lyases, discovery and assays, Anti-infective target 1-deoxy-d-xylulose-5... synthase (DXS) and drug design for enzyme inhibition, Expression, Purification, and Mechanistic Studies of DXP synthases from Deinococcus radiodurans, Plasmodium falciparum, and Plasmodium vivax, Comparison of the catalysis of ThPP-dependent enzymes AHAS, ALS, and DXS, and much more.Additional sections cover Plant and fungal acetohydroxyacid synthases (AHAS): Methods for heterologous expression, kinetic characterization, and structural analysis, Biochemical and Structural characterization of novel ‘split-gene’ archeal transketolases, 4-Hydroxybenzoylform... decarboxylase enzymes from Rhodococcus jostii RHA1 and Pseudomonas fluorescens Pf-5: characterization and involvement in bacterial lignin degradation, Engineering of phosphoketolase from Bifidobacterium adolescentis for increased activity on non-phosphorylated substrates and application in a cell-free reaction system for ATP regeneration, Repurposing TPP-dependent enzymes with anodic oxidation for the conversion of aldehydes to enantioenriched carboxylic acids, and much more.

  • Biology

    A Human Health Perspective
    • 1st Edition
    • Harry E. Peery + 2 more
    • English
    Biology: A Human Health Perspective offers important medical case histories and complex color illustrations, interacts with the reader, and asks questions throughout. Sections cover the basic chemistry of biology and cell origins, and energy and protein processing before discussing cell reproduction, genetics, evolution, and their place in public healthcare. Clinical applications and medical terminology are also included across chapters, and pioneering medical developments such as holographic surgery, robotic neurosurgery, and tractography are featured.This textbook, along with supporting ancillary materials such as PowerPoint slides, solution manuals and quiz banks is a vital resource for all undergraduate students studying biology or for those looking to develop a career in a health profession who need a basic understanding of the field.

  • Insect Pathology

    • 3rd Edition
    • Nemat Keyhani + 2 more
    • English
    Insect Pathology, Third Edition offers the most comprehensive research on the topic of insect pathology, spanning the diversity of insects with a more diverse array of microbes. This book provides a full update on new approaches for studying the genetics, development, evolution, and ecology of insect pathogens. Written by leading researchers and experts, the book includes coverage of revolutionary genome editing tools, such as CRISPR-Cas9, which have been developed for multiple insect pathogen systems and provides insights into the molecular underpinnings of insect pathogens and their hosts. This book also updates modern molecular techniques, “omics” approaches, and newly applied findings. These new and revised topics are critical for understanding current perspectives in the field, making this book a needed reference for insect pathologists, entomologists, microbiologists, mycologists, nematologists, protistologists, ecologists, and practitioners of biological control of insect pests. New and long-time students of insect pathology will also find this new edition useful.

  • Technology-Assisted Physical Gait Rehabilitation

    How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy
    • 1st Edition
    • Tomislav Baček + 3 more
    • English
    Technology-Assisted Physical Gait Rehabilitation: How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy explores computational modeling techniques, robotic assistance, data science, and other technological tools and how they can be jointly used in driving and guiding physical gait therapy in impairments such as stroke, traumatic brain injury, and incomplete spinal cord injury. This book gathers experts in robotics, human biomechanics, physical therapy, neuroscience, engineering, and medicine, presenting their ongoing work and discussing their views on the future direction of technology-assisted gait therapy. It showcases the latest advancements in the interdisciplinary and multidisciplinary field of technology-assisted gait therapy and strives to outline the developments in the coming years that are needed/likely to make the next big breakthrough in the field.

  • Dry Eye Disease

    A Clinical Handbook
    • 1st Edition
    • James Stuart William Wolffsohn + 2 more
    • English
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.

  • Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology

    • 1st Edition
    • Swagat Kumar Das + 2 more
    • English
    Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology delves into historical perspectives, current trends, and future projections for research and development of immunological and biopharmaceutical products. Sections explore immunostimulants, natural and synthetic immunostimulants in aquaculture and animal husbandry, immunomodulators, immune boosters, pre- and probiotics in health promotion, cutting-edge immunological techniques for disease diagnosis, immunotherapy in cancer treatment, and transplantation immunology. Following chapters explore the impact on pharmaceutical biotechnology, with discussions on traditional and modern approaches in drug delivery, in silico drug delivery modeling, biocomposites and their pharmaceutical applications, recent advances in monoclonal antibodies production, vaccine development, and much more. Finally, the book covers the pivotal role of AI, machine learning, and data analytics in the clinical study of immunotherapy and pharmaceutical drugs, thus paving the way for enhanced research and development efficiency. Researchers in industry and academia alike will gain valuable insights into the novel principles behind designing and developing immunological and drug products, making this title an essential resource.

  • Organic Semiconducting Systems for Applications in Biomedical Engineering

    • 1st Edition
    • Neha Rani Kumar + 1 more
    • English
    Organic Semiconducting Systems for Applications in Biomedical Engineering explores the properties and applications of organic semiconductors, which are conjugated systems made from small organic molecules or polymers that exhibit semiconductor characteristics. These materials offer flexibility, lightweight construction, low cost, and large-area production capabilities. Their tunable electronic and optical properties, along with biocompatibility, such as biosensors, smart drug delivery systems, medical diagnostics, and implantable devices.The book targets professionals and students in the fields of organic electronics, biomedical engineering, biomaterials, and environmental science. It provides a comprehensive understanding of organic conjugated systems and their principles, aiding readers in designing innovative solutions for challenges in medical sectors. Additionally, it delves into the latest research findings and practical applications of organic semiconductors, helping readers stay informed and identify new research opportunities. This book clarifies complex concepts, making it suitable for beginners. It also offers a forward-looking perspective on the potential of organic semiconductors to revolutionize biotechnology, inspiring readers to pursue research and innovation for sustainable development.Overall, this book serves as an essential resource for understanding organic semiconductors in biotechnology, biomedical engineering, and bioelectronic applications.

  • Perianal Crohn’s Disease

    Diagnosis and Treatment
    • 1st Edition
    • Bolin Yang + 2 more
    • English
    Perianal Crohn’s Disease: Diagnosis and Treatment includes the latest knowledge, concepts, first-hand theoretical views, and clinical experience of clinical frontline experts in the field of inflammatory bowel disease. The book systematically describes disease phenotypes, clinical features, examination methods, diagnoses, and treatments. It takes a scientific, practical, and systematic account of both common and rare conditions associated with Perianal Crohn’s Disease, offering informative content, clinical case information, cutting-edge viewpoints, and current, authoritative research findings. The book contains a depth of current clinical experience, including the use of photographs to support examples of conditions, methods, and techniques. In addition, it provides clear ideas and a wealth of clinical information for the clinical diagnosis and management of perianal Crohn's disease.

  • Neurogynecology and Associated Neurological Disorders

    • 1st Edition
    • Vishal K. Chavda + 2 more
    • English
    Neurogynecology and Associated Neurological Disorders addresses the emerging interdisciplinary field linking neurology and gynecology, focusing on how neurological disorders impact female reproductive health throughout the lifespan. The book covers foundational neuroanatomy, hormonal influences on neurological function, and specific disorders including headaches, epilepsy, pelvic neuropathies, and mental health conditions related to reproductive stages. It includes clinical guidelines, case studies, diagnostic tools, and treatment protocols tailored to hormonal phases and life stages. The integration of neurobiological mechanisms with gynecological considerations offers readers a robust framework for interdisciplinary collaboration.Reader... will find this to be a great reference that responds to the growing clinical need for integrated understanding and management of conditions such as menstrual migraines, pregnancy-related neuropathies, and menopausal neurological changes.

  • Lightweight, Real-time Deep Learning Models for Healthcare Applications

    • 1st Edition
    • Tina Babu + 2 more
    • English
    Lightweight, Real-time Deep Learning Models for Healthcare Applications addresses the pressing need for deploying efficient artificial intelligence models in clinical environments constrained by limited computational resources. As AI adoption accelerates in healthcare, this reference targets the gap between advanced deep learning research and practical real-time applications, emphasizing model optimization, privacy, and regulatory compliance. The content comprehensively covers model compression techniques such as pruning, quantization, knowledge distillation, and neural architecture search, alongside federated learning frameworks and real-time inference optimization. Detailed chapters present hardware-aware strategies, security considerations, continuous learning, and regulatory validation. The book also provides extensive case studies and implementation blueprints demonstrating practical deployment on devices like Raspberry Pi, NVIDIA Jetson, and mobile health platforms. This book benefits researchers, clinicians, and healthcare technology professionals by offering practical solutions to develop, validate, and implement AI models that maintain diagnostic accuracy while meeting clinical constraints. It equips students and educators with theoretical foundations and hands-on examples to foster innovation in biomedical AI, ultimately enhancing diagnostic capabilities and patient care in diverse healthcare settings.

  • Cell Death Part F

    • 1st Edition
    • Volume 211
    • English
    Cell Death: Part F, Volume 211 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores Methods to Assess BAX Conformation, Activation, Translocation, and Mitochondrial Outer Membrane Permeabilization, Proximity biotin labelling identification of Bcl-2 protein interactions in live cells, Bimolecular fluorescence complementation assays for investigating Bcl-2 family protein interactions, Assessing apoptotic sensitivity in primary mouse B cells by BH3 profiling, Liposome permeabilization assays to monitor pore formation by cell death proteins, Flow Cytometry Assessment of Mitochondrial Membrane Potential, Biomass, and ROS in OXPHOS-Dependent and Glycolytic Cancer Cells during Cell Death Induction, and much more.Additional chapters cover Assessment of Viability Versus Cell Death: What is What?, Flow cytometry-based drug response profiling of primary B-precursor ALL cells in co-culture with bone marrow-derived stromal cells, An in vitro model of efferocytosis in macrophage foam cells to probe lipid-driven dysregulation of dead cell clearance, Measuring tumor cell killing using in vivo bioluminescence imaging, and more.

  • Personalized Cancer Medicine through Multiomics

    • 1st Edition
    • Mohammad Azhar Aziz + 1 more
    • English
    Personalized Cancer Medicine through Multiomics explores the integration of multiomics to transform cancer diagnosis and treatment. The book delves into how the convergence of genomics, transcriptomics, proteomics, and metabolomics offers a comprehensive understanding of cancer biology, surpassing traditional single-omics approaches. Sections detail advancements in high-throughput technologies and computational methods, including machine learning, that enable the analysis of complex cancer datasets. Additional content discusses how multiomics identifies unique molecular signatures, novel therapeutic targets, and biomarkers, facilitating precise and individualized treatment strategies, particularly for a heterogeneous cancers.For academics, this book serves as an essential resource, compiling fragmented research into a single, coherent volume. It provides foundational knowledge, the latest advancements, and practical applications of multiomics in personalized medicine. Researchers will benefit from interdisciplinary approaches, real-world examples, and cutting-edge methodologies, making it an invaluable reference for advancing their work in oncology.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 44
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 43 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Content in this new release covers Engineered probiotics for producing phosphoinositol-sn-l... as biosurfactant modulators: Their hydropathy, in potentiating surface tension and scaffold properties into model emulsions.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part A

    • 1st Edition
    • Volume 191
    • English
    Blood-Based Biomarkers for Alzheimer’s and Parkinson’s Disease, Volume 191 in the International Review of Neurobiology series, presents current advances and comprehensive reviews on the development and application of circulating biomarkers in neurodegenerative disorders. It brings together contributions from an international panel, highlighting emerging strategies for early detection, diagnosis, and monitoring of Alzheimer’s and Parkinson’s diseases. Chapters explore a wide range of topics, including the Diagnostic Potential of Exosomes in Neurodegenerative Diseases and Cancer, Blood Biomarkers of Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s and Parkinson’s Diseases, GFAP and the Genetic Code of Astrocyte Activation in Alzheimer’s Disease, and much more.Additional chapters cover Blood-Based Emerging Biomarkers in Early Detection and Diagnosis of Alzheimer’s Disease, Advances in Nanomaterial-Based Biomarker Detection for Neurodegenerative Diseases, Blood-Based Biomarkers in Alzheimer’s and Parkinson’s Disease: From Molecular Pathology to Therapeutic Potential, Blood-Based Biomarkers and Their Role in AD/PD Diagnosis, The Emerging Landscape of Circulatory Biomarkers in Alzheimer’s Disease, Biofluid-Based Biosensors, Biomarkers of Vascular Dementia and Alzheimer’s Disease, Silent Clues in Blood: Proteomic Approach for Alzheimer’s Disease, and more.

  • Animal Models of Disease Part F

    • 1st Edition
    • Volume 212
    • English
    Animal Models of Disease, Part F, Volume 212 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

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