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Elsevier

Books in Life sciences

  • Clean Label Starch

    Processes, Properties and Functionality
    • 1st Edition
    • Parmjit Singh Panesar + 1 more
    • English
    Clean Label Starch: Processes, Properties and Functionality, a volume in the "Applications of Starches in Food and Packaging" series, provides the most up-to-date information on clean label starches, catering to a wide range of readers interested in starch modification and its applications in clean label food and packaging industries. Chapters cover hydro-thermal clean label starch, thermal and non-thermal physically modified starches, biotechnological approaches for clean label starch production, and its nanoencapsulation. Applications of clean label starch in the edible packaging industry, biodegradable packaging, and in bakery and confectionery are also included. The book discusses the challenges, and consumer acceptability, in addition to the quality attributes of clean label starch. Edited by an internationally diverse group of experts and leaders who possess extensive, up-to-date knowledge of native and modified starches and related technologies, this book is an excellent resource which highlights important global perspectives in the field.

  • Advances in Edible Packaging Systems for Food Preservation

    Processing, Bioactive Agents and Preservation
    • 1st Edition
    • Zuhaib F. Bhat + 1 more
    • English
    Advances in Edible Packaging Systems for Food Preservation: Processing, Bioactive Agents and Preservation discusses the edible packaging systems available for the preservation of all types of foods and products derived from meat, eggs, milk, plants, cereals, fish, and seafood. Divided into 14 chapters, the book covers recent topics related to edible packaging such as the role of emerging technologies (including cold plasma, ultrasonication, electrospinning, high-pressure, 3D printing, and pulsed light), alternative film materials (including insect, fungal, and algae proteins), novel bioactive agents (including novel peptides and nanoemulsions, nanoparticles, and nanofibers from novel sources), engineering aspects, environmental impacts, and consumer perception.This book caters to a wider audience, including, but not limited to, individuals involved in food science, meat science, dairy science, food packaging, agriculture sciences, protein and carbohydrate biochemistry, and nutrition.

  • Artificial Intelligence in Precision Drug Design, Volume 2

    Advanced Applications
    • 1st Edition
    • Khalid Raza
    • English
    Artificial Intelligence in Precision Drug Design, Volume 2: Advanced Applications explores the transformative role of AI in modern drug discovery and development, presenting cutting-edge research and methodologies that integrate machine learning, network pharmacology, and computational modeling to accelerate therapeutic innovation. It covers a wide range of applications, including AI-driven drug repurposing, combination therapies, cancer immunotherapy, neuroscience, vaccine development, and molecular dynamics, but also delves into emerging technologies such as quantum computing, large language models, and graph neural networks. Designed for academics, this volume provides researchers, clinicians, and graduate students with a resource on the latest AI methodologies in precision medicine.Users will find this to be a great resource that supports evidence-based innovation, fosters interdisciplinary collaboration, and equips them with insights to advance personalized healthcare solutions.

  • Encyclopedia of Endocrine Diseases

    • 3rd Edition
    • Ilpo Huhtaniemi
    • English
    The Encyclopedia of Endocrine Diseases, Third Edition, Five Volume Set is an essential one-stop reference exploring physiological, clinical diagnostic and therapeutic aspects of a wide range of endocrine and endocrine-related metabolic diseases. This edition incorporates ground-breaking research that has occurred in the last 8 years particularly in molecular mechanisms such as mutations, epigenetics and signaling, environmental effects on homeostasis, and the pathogenesis of common endocrine diseases including endocrine malignancies, obesity, and diabetes.Among the most complex constructs in the body, the endocrine system sends chemical signals to specific receptors in other parts of the body, eliciting intracellular signaling pathways as their biological effect. The endocrine system regulates numerous processes including metabolism, biological cycles, internal fluid volume, reproduction and growth to maintain body homeostasis. However, the ways in which endocrine functioning can go awry are numerous. Providing over 420 updated articles, this 5 volume edition of Encyclopedia of Endocrine Diseases explores the extensive spectrum of metabolic and endocrine disease, capturing new diagnosis techniques, treatment methods and understanding of endocrine pathogenesis.This text, unique in its vast coverage and clear layout, is not only an indispensable resource for clinical professionals and researchers in endocrinology, but also accessible to advanced and undergraduate students.

  • Sustainable Agricultural Waste Management

    Advantages, Challenges, and Further Improvements
    • 1st Edition
    • Indrajeet Kumar + 3 more
    • English
    Sustainable Agricultural Waste Management presents a thorough and forward-looking examination of the multifaceted challenges and opportunities in managing agricultural waste sustainably. The volume guides readers through the ecological, technological, and socio-economic dimensions of agrowaste, from its impact on soil, air, and water to the latest advances in circular economy strategies, biochar, and nanotechnology-drive... solutions.Expertly curated chapters address the valorization of agrowaste into bioactive compounds, clean energy, and eco-friendly nanomaterials, while also evaluating economic viability, policy frameworks, and regulatory mechanisms. The book’s integrative approach bridges traditional practices with next-generation innovations, offering actionable insights for immediate application and inspiring future research.This essential resource is designed for advanced students, researchers, practitioners, policymakers, and environmental advocates seeking to drive meaningful changes in agricultural systems worldwide.

  • Using Stimulants to Improve Plant Health

    From Stress to Strength
    • 1st Edition
    • Arafat Abdel Hamed Abdel Latef
    • English
    Using Stimulants to Improve Plant Health examines biostimulants, chemical growth regulators, and phytohormones as levers to bolster plant resilience and productivity under abiotic and biotic stress. It outlines the physiological, biochemical, and molecular mechanisms that enable these agents to enhance tolerance to adverse soil and weather conditions and highlights cutting-edge advances in nanotechnology and precision agriculture.With applied guidance insights, sample protocols, and real-world case studies, readers learn how to integrate stimulant-based strategies into operations—from smallholder farms to large-scale production—while prioritizing financially sound and ecologically responsible practices.Structured into 16 chapters, each surveying a specific class of bioactive compounds and their modes of action, with practical agricultural applications, this authoritative volume will be invaluable to researchers, agronomists, extension professionals, and plant biologists dedicated to promoting plant health, achieving greater robustness and yield outcomes.

  • Cutting Edge Advances in Transplantation

    • 1st Edition
    • Dai Dao Nghiem
    • English
    Cutting Edge Advances in Transplantation presents the current state of the science of transplantation. With a unique interdisciplinary approach, this reference collects contributions from selected transplant surgeons, scientists, and immunologists who have worked in the field for the last thirty years. Coverage includes transplantation tolerance, the molecular approach to transplant monitoring, sensitized transplant recipients, xenotransplantation, biologics, and regifted organs. This is the perfect reference for transplant surgeons and nephrologists that want to find new approaches and solutions to serve their patients. It is also ideal for transplantation researchers looking for the most up-to-date scientific information related to the field which can be built upon.

  • The Story of GLP-1

    A Historical Journey in the Treatment of Diabetes and Obesity
    • 1st Edition
    • Jens Juul Holst
    • English
    The Story of GLP-1: A Historical Journey in the Treatment of Diabetes and Obesity offers a compelling narrative about the discovery and development of the hormone GLP-1, which has revolutionized modern approaches to diabetes and obesity. Award-winning scientist Professor Jens Juul Holst, alongside co-authors Professor Sten Madsbad, Professor Jens Meldgaard Bruun, and Novo Nordisk Foundation CEO Mads Krogsgaard Thomsen, trace the scientific breakthroughs and clinical advances that have made GLP-1 therapies, such as Ozempic and Wegovy, essential tools for improving blood sugar control and promoting meaningful, lasting weight loss in patients worldwide.The book explores the rising global prevalence of obesity and diabetes, emphasizing the urgent need for innovative solutions. It critically examines traditional treatments, noting their limitations in sustaining weight loss or reducing complications. The narrative details the paradigm shift brought by GLP-1 medications, including liraglutide and semaglutide, which offer improved cardiovascular outcomes and significant health benefits. The authors also address ongoing challenges of accessibility and affordability, prompting important societal discussions about equitable distribution and funding for these lifechanging therapies.

  • Diabetes, Aging, and Management Strategies

    Cellular Mechanisms for Healthy Aging
    • 1st Edition
    • Younis Ahmad Hajam + 2 more
    • English
    Diabetes, Aging, and Management Strategies: Cellular Mechanisms for Healthy Aging is a comprehensive guide that explores the complex interplay between diabetes and the aging process. The book dives deeply into the scientific mechanisms underlying diabetes and aging, offering insights into how aging accelerates disease processes and affects metabolic pathways, organ function, and overall health. With a focus on the biological, clinical, and practical aspects of diabetes in the elderly, this book provides actionable information on the pathophysiology of diabetes in aging individuals, evidence-based mitigation strategies, and effective management approaches.As populations worldwide grow older, the prevalence of diabetes continues to rise, presenting new challenges in understanding, managing, and mitigating the effects of this condition on older adults. This book is designed to support healthcare professionals, researchers, and policymakers in creating and implementing strategies that address the unique needs of this population.

  • Exploring Plant Peptide Potentials

    A Comprehensive Guide
    • 1st Edition
    • Abhijit Sarkar + 3 more
    • English
    Exploring Plant Peptide Potentials offers an in-depth overview of the latest research on these functional molecules, emphasizing their diverse biological roles and growing relevance across disciplines. The book brings together insights into their discovery, mechanisms, and applications to deepen understanding and inspire future research.Plant peptides are key regulators of growth, development, defense, and stress responses, and they show considerable promise in pharmaceutical, nutraceutical, and herbal medicine applications. The volume spans topics from peptide identification and imaging to signaling pathways, molecular interactions, and bioinformatics approaches. It also covers both conventional and advanced tools in peptide science, including post-translational modifications, peptide mimicry, and innovations in nanotechnology and biotechnology.Explor... Plant Peptide Potentials is a valuable resource for researchers and professionals in plant biochemistry, physiology, molecular biology, and biotechnology, as well as those developing plant-derived health and therapeutic products.

  • Harnessing the Potential of Blockchain Technology in the Smart Healthcare

    • 1st Edition
    • Pankaj Bhambri + 2 more
    • English
    Harnessing the Potential of Blockchain Technology in the Smart Healthcare explores a groundbreaking shift in how healthcare data are managed, shared, and secured. This book is an essential guide for anyone seeking a deep understanding of the intersection between blockchain and healthcare. It breaks down complex blockchain concepts and reveals their transformative impact on the industry.Across 27 insightful chapters, the readers will discover how blockchain can not only revolutionize electronic health records, strengthen data security and privacy, and streamline healthcare operations, but also empower patients with greater control over their health information.Through real-world case studies, expert insights, and practical strategies, the book equips healthcare professionals, technologists, and policymakers with the tools to leverage blockchain for a more efficient, transparent, and patient-centered healthcare system.By examining real-world applications and implementations, this book not only informs but also inspires action—paving the way for a future where healthcare is smarter, safer, and more equitable.

  • Sports Biomechanics

    Theories, Examples, and Data Analysis
    • 1st Edition
    • Boyi Dai + 2 more
    • English
    Sports Biomechanics: Theories, Examples, and Data Analysis provides mechanical theories, data-based examples, and step-by-step analyses in MATLAB, giving a comprehensive understanding of the process of performing biomechanical analysis in sports. The book connects theories with principles of data collection and offers specific data analysis techniques. It addresses gaps among theories, raw data from various collection methods, different calculations to process raw data in MATLAB, and the extraction of variables of interest to quantify sports performance and injury risk. Sample raw data, videos, figures, and MATLAB scripts are provided, along with theories to calculate key parameters in different sporting events and movements.Readers are encouraged to replicate the data collection and data analyses listed in the book and translate the knowledge and skills to a different setting. While this book covers the data analyses in MATLAB, programming skills can be related to other software with similar language environments to help readers ask questions and understand different parameters when using software performing automatic data processing.

  • Biomechanics of the Human Spine

    Basic Concepts, Spinal Disorders and Treatments
    • 2nd Edition
    • Fabio Galbusera + 1 more
    • English
    Biomechanics of the Human Spine: Basic Concepts, Spinal Disorders and Treatments, Second Edition is an essential resource for both biomedical engineers and spinal surgeons. The book is divided into four key sections, each building on the previous to offer a thorough understanding of spine biomechanics. It starts with the functional anatomy of the spine, emphasizing often overlooked aspects of clinical literature. The second section details the mechanics of spinal tissues, including testing setups and mathematical models. The third section explores contemporary spine research methods, while the final section addresses biomechanical aspects of spinal pathologies and their surgical treatments.Contribut... from leading institutions worldwide ensure the inclusion of the latest research and expertise in spine biomechanics. Highlights include in-depth experimental testing, numerical simulation, and in vivo studies, such as imaging and motion analysis. The book stands out for its comprehensive approach, bridging the gap between biomechanical knowledge and clinical application. It is indispensable for professionals in the field, offering valuable insights and practical guidance for understanding and treating spinal disorders.

  • Alternative Dairy Products and Technologies

    • 1st Edition
    • Harjinder Singh + 1 more
    • English
    Alternative Dairy Products and Technologies comprehensively covers the available products on the market, including processing, sensory qualities, and nutritional value in comparison to dairy milk. The book also looks ahead to new and emerging biotechnologies—such as molecular farming and precision fermentation—that promise to create near-identical products to animal derived dairy. Bringing together key issues of environmental sustainability, human nutrition, biotechnology, and product development, this book is an interdisciplinary reference written and edited by a global team of experts from a variety of fields.It will be of significant value to academics, scientists, and students as this is a very hot topic in the food science area. Additionally, this book will be a great resource for the food industry and many start-up companies currently working on developing innovative alternative proteins and dairy products.

  • Neurobiology of Type 2 Diabetes

    • 1st Edition
    • Shovit Ranjan + 2 more
    • English
    The "Neurobiology of Type 2 Diabetes" delves into the intricate interplay between the nervous system and the development, progression, and management of Type 2 Diabetes. This comprehensive volume explores the often-overlooked neurological aspects of diabetes, offering a unique perspective on the disease. The purpose of this book is to bridge the gap between neuroscience and diabetes research, providing a consolidated resource that elucidates the complex relationship between the brain and metabolic regulation. By synthesizing the latest scientific findings, the book aims to offer researchers, clinicians, and students a deep understanding of how neural pathways influence glucose homeostasis, insulin sensitivity, and the emergence of diabetic complications.

  • Emerging Trends in Cancer Pharmacology

    From Molecular Targets to Personalized Medicine
    • 1st Edition
    • Tapan Behl + 4 more
    • English
    Emerging Trends in Cancer Pharmacology: From Molecular Targets to Personalized Medicine gives readers a comprehensive and up-to-date resource on the latest developments and trends in the field of cancer pharmacology. It serves as a valuable reference for researchers, scientists, clinicians, and other professionals involved in cancer research, pharmacology, oncology, and personalized medicine. In recent years, there have been significant breakthroughs in understanding the molecular mechanisms of cancer and the development of targeted therapies. Additionally, personalized medicine has emerged as a promising approach to tailor treatments based on an individual's genetic profile, tumor characteristics, and other factors. These developments have the potential to revolutionize cancer treatment and improve patient outcomes. This book covers such developments.

  • Aquaculture Mycology and Bacteriology

    • 1st Edition
    • Frederick S.B. Kibenge + 2 more
    • English
    Aquaculture Mycology and Bacteriology is a practical reference to address the steadily increasing importance of infectious diseases of aquatic animals. With the burgeoning expansion of the animal aquaculture industry to new geographic areas, new microbial and parasitic species with pathogenic potential will continue to emerge. This necessitates rapid identification of the new pathogens to enable their control. Each pathogenic bacterial or fungal species is accompanied by the full description of both taxonomic and clinical information for the three major aquatic food animals (fish, crustaceans and mollusks).Aquacultur... Mycology and Bacteriology takes a comprehensive approach to facilitate research to develop vaccines or other similar pathogen mitigation measures, and is useful to bacteriologists, mycologists, aquaculturists, clinical practitioners in aquatic animal health and all those in industry, government or academia who are interested in aquaculture, fisheries and comparative biology.

  • Animal Models of Disease Part E

    • 1st Edition
    • Volume 203
    • English
    Animal Models of Disease, Part E, Volume 203 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Autoimmune Encephalitis and Paraneoplastic Syndrome

    Current Knowledge and Updates
    • 1st Edition
    • Shitiz Sriwastava
    • English
    Autoimmune Encephalitis and Paraneoplastic Syndrome: Current Knowledge and Updates provides an overview of the immune-driven disorders of the nervous system, particularly autoimmune encephalitis. By integrating case studies, flow charts, and clinical examples throughout, the book helps users navigate the complexities of autoimmune encephalitis. Sections also address demographic traits, tumor correlations, and outcomes, equipping readers with essential knowledge for diagnosis and management. With a strong focus on classifying these disorders, defining their pathogenesis and pathophysiology, and examining recent treatment guidelines, this book serves as a comprehensive guide for clinicians, neurologists, and researchers in neuroimmunology.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 51
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 51 provides comprehensive profiles of four pharmaceutical compounds: Vortioxetine, Rosuvastatin Calcium, Perindopril, and Ferulic Acid. In addition, it includes a review article concerning Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases. Chapters in this new release include Vortioxetine: A Comprehensive Profile, Rosuvastatin Calcium: A Comprehensive Profile, Ferulic Acid: A Comprehensive Profile, Perindopril: A Comprehensive Profile, Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases, Kinetic Exclusion Assay Technology: Theory, Experimental Aspects, and Applications in Concentration Measurements Across Diverse Fields, and more.No other book series provides this essential information as promptly and pertinently. Sections provide review articles and database compilations categorized into five primary domains: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Pertaining to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis.

  • Live Biotherapeutics: Advancing Microbial Medicine

    • 1st Edition
    • Volume 220
    • English
    Microbial therapeutics are rapidly reshaping modern medicine, with live biotherapeutics emerging as a promising frontier. By harnessing the power of beneficial microbes, these innovative treatments offer new hope for conditions that resist conventional drugs, including metabolic disorders and antimicrobial-resist... infections. As the demand for safer, more effective alternatives grows, understanding this field becomes increasingly vital. The upcoming book, Live Biotherapeutics: Advancing Microbial Medicine, will provide a comprehensive and accessible overview of the science, applications, and future potential of live biotherapeutics in transforming healthcare.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 131
    • English
    Advances in Clinical Chemistry, Volume 131 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Advances in Volatile Organic Compound Biomarker Detection, 2D-DIGE proteomics, Interacting partners of Tau protein in Alzheimer’s disease, Biosensors for Detection of Autoimmune Disease, Small Molecule Biomarkers in Infectious Disease, and Diagnosis and Risk Factors in Pancreatogenic Diabetes. Each chapter is written by an international board of authors.

  • Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer - Part B

    • 1st Edition
    • Volume 399
    • English
    Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part B delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Liquid biopsy approaches to capture minimal residual disease and therapy response in patients with early stage cancers, Identification of circulating biomarkers for cancer therapy-related cardiovascular toxicity, Extracellular Vesicles as Dynamic Biomarkers: Monitoring Therapeutic Responses and Drug Resistance in Cancer, and more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

  • Lipids and Membranes: Detection by Imaging and Lipidomics

    • 1st Edition
    • Volume 726
    • English
    Lipids and Membranes: Detection by Imaging and Lipidomics, Volume 727 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the chapters in this new release include Measurement of fatty acid esters of hydroxy fatty acids, Superresolution organelle imaging with lipophilic HIDE probes, Ultra-high resolution analysis of membrane lipids from 15N metabolically labeled mice, Superresolution lipid imaging with expansion microscopy, High-resolution phosphoinositide analysis in healthy versus disease cells, and much more.Additional chapters focus on Alkyne lipids as tracers of lipid metabolism, Imaging oxidative stress in biomembranes, Imaging the dynamics of phosphatidylinositol 4-phosphate metabolism, Lipidomics for studying sphingolipids in cell death, Non-invasive imaging of phosphoinositides with genetically encoded lipid biosensors, Profiling lipotypes at the single cell level in heterogenous populations, MS imaging of phosphoinositides, and much more.

  • Artificial Intelligence in Precision Drug Design, Volume 1

    Foundations and Core Techniques
    • 1st Edition
    • Khalid Raza
    • English
    Artificial Intelligence in Precision Drug Design: Advanced Applications showcases how artificial intelligence (AI) is revolutionizing modern drug discovery and development. Building upon the foundational principles established in Volume 1, this book dives into real-world applications where AI accelerates innovation, enhances predictive accuracy, and enables breakthrough therapeutics. Featuring contributions from leading global researchers and practitioners, the book explores machine learning, deep learning, and network-based approaches applied to complex biomedical challenges. Key areas include AI driven drug repurposing, combination therapies, immunotherapy, vaccine design, quantum computing, and the integration of large language models in drug discovery. Additional chapters highlight predictive modeling using electronic health records, AI-powered medical imaging, and explainable AI for structure-based drug design. What sets this volume apart is its emphasis on practical impact, demonstrating how data, computation, and interdisciplinary collaboration converge to advance precision medicine. Designed for scientists, clinicians, educators, and students, it serves as both a comprehensive reference and a source of inspiration for leveraging AI to transform healthcare.

  • Neurobiology and Artificial Intelligence

    Medical, Social and Ethical Implications
    • 1st Edition
    • Luca Saba
    • English
    Neurobiology and Artificial Intelligence: Medical, Social, and Ethical Implicationsexplores the dynamic intersection of neurobiology and artificial intelligence (AI),investigating the scientific, philosophical, and ethical implications of these rapidlyevolving fields. By blending cutting-edge research with thought-provoking discussions,this book aims to make complex topics accessible to an interdisciplinary audience,from researchers and upper graduate students eager to understand how AI andneuroscience shape our understanding of intelligence, creativity, learning, and thehuman condition.

  • Agricultural Applications of Earth Observation

    • 1st Edition
    • Peng Fu
    • English
    Agricultural Applications of Earth Observation details the revolutionary impact of satellite and remote sensing technologies in enhancing agricultural practices. It bridges the knowledge gap by making advanced satellite and sensor data understandable and applicable, enabling readers to select the best tools for specific agricultural needs. Real-world case studies and practical examples demonstrate the successful implementation of Earth Observation technologies in agriculture, inspiring readers with tangible results and encouraging innovative thinking. Agricultural Applications of Earth Observation enables readers to apply Earth Observation technologies to enhance agronomical sustainability and contribute to more environmentally friendly practices. With detailed methodologies and a range of additional supplementary elements, the book equips readers with the knowledge and tools to drive the future of agriculture into a more sustainable era.

  • Lipid Nanoparticles-Based mRNA Delivery System

    • 1st Edition
    • Raj Kumar
    • English
    Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. The book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration—such as intravenous, oral, transdermal, and intranasal delivery.The book also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. Final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field.

  • Agricultural Biostimulants for Mitigation of Salt, Drought, and Heat Stress

    • 1st Edition
    • M. Naeem + 1 more
    • English
    Agricultural Biostimulants for Mitigation of Salt, Drought, and Heat Stress provides up-to-date information on sustainable strategies to enhance the resilience of agricultural crops under adverse environmental conditions. As part of the Biostimulants and Protective Biochemical Agents series, this volume focuses on high-impact challenges and emerging opportunities in crop stress management.Biostimul... represent a promising and effective approach to achieving sustainable agriculture. Widely regarded as renewable sources of plant nutrients, they can enhance crop productivity and improve soil health. Over the past decade, there has been growing interest in the use of diverse biostimulants—includ... plant growth-promoting fungi, rhizobacteria, seaweed extracts, and organic amendments—to increase nutrient use efficiency and boost plant tolerance to abiotic stresses.This book covers a range of key biostimulant categories such as bacteria, algae, plant growth regulators (PGRs), plant growth-promoting bacteria (PGPB), biochar, and other core approaches. It explores how specific biostimulants contribute to protecting and enhancing plant health and is the first comprehensive reference to focus exclusively on their role in safeguarding crop yields under salt, drought, and heat stress conditions.

  • Episodes in the History of Medical Science

    Discovery Meets Orthodoxy
    • 1st Edition
    • Anthony R. Rees
    • English
    Episodes in the History of Medical Science: Discovery Meets Orthodoxy highlights key moments in history where scientific and medical advances faced acceptance and rejection by the prevailing orthodoxy. This book places present-day disease protection in context by exploring significant medical and scientific theories, their success stories, challenges, and the frequent resistance to new ideas. It shows how acceptance of scientific discoveries often lags due to conservatism within the scientific community and broader socio-political and cultural influences. The book examines the origins of medical theory and practice, from the revolutionary ideas of Hippocrates and Galen to the rise of Islamic Medicine and the scholasticism of the Middle Ages. It covers the arrival of syphilis in Europe and the ensuing medical debates, the historical battle against smallpox through variolation and vaccination, and the skepticism faced by groundbreaking discoveries in the 19th and 20th centuries. Key topics include the gene debate, the thalidomide tragedy, the antibody revolution, and the paradigm shift in understanding stomach ulcers. The narrative also addresses the modern era's anti-vaccinationism and vaccine hesitancy, emphasizing the ongoing tension between scientific integrity and public acceptance. Episodes in the History of Medical Science: Discovery Meets Orthodoxy is a valuable resource for medical professionals, researchers, historians, and students. It underscores the importance of scientific and medical integrity, the pursuit of truth, and validated scientific communication. By providing historical insights and examples of perseverance in the face of skepticism, this book offers valuable lessons for improving public health and understanding the dynamic journey of medical science.

  • Inmunología

    • 10th Edition
    • David Male + 2 more
    • Spanish
    Nueva edición de uno de los textos de referencia en inmunología de nuestro portfolio en el que se abordan de forma equilibrada e integrada los conceptos pertenecientes a la inmunología básica y clínica. La estructura general de esta edición de Inmunología es la misma que la de la novena edición, Las secciones 1 y 2 describen el funcionamiento del sistema inmunitario. La sección 3 se ocupa de las respuestas inmunitarias contra los microorganismos patógenos (la función principal del sistema inmunitario), y las secciones 4 a 6 abordan aspectos de inmunología clínica, como las enfermedades autoinmunitarias, la inmunodeficiencia, los trasplantes, la inmunología tumoral y la hipersensibilidad. Todos los capítulos se han actualizado por completo e incluyen numerosos diagramas nuevos. Especial atención merecen los Caps. 17,18,20 y 22 por su profunda actualización en temas relativos a las nuevas vacunas de mRNA, inmunización pasiva, autoinmunidad, nuevos anticuerpos y nuevas terapias celulares y los nuevos descubrimientos a raíz de la epidemia de Covid. Las secciones de razonamiento crítico que siguen a cada capítulo requieren la comprensión del material presentado y de las implicaciones en un entorno de laboratorio o clínico, y sirven como base para el debate en el aula. Otro importante instrumento pedagógico son los resúmenes que recogen los puntos clave de cada capítulo, así como los numerosos esquemas, diagramas y figuras. La nueva edición ofrece contenido adicional online en español a través de la plataforma e-book+. Incluye apartados, tablas y figuras adicionales, así como una colección de 15 videos.

  • Mitochondria and Cancer

    From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse
    • 1st Edition
    • Farzad Taghizadeh-Hesary + 3 more
    • English
    Mitochondria and Cancer: From Basic Science to Clinical Applications—Underst... Pathogenesis, Therapy Resistance, and Disease Relapse offers comprehensive perspectives about the role of mitochondria in cancer biology and treatment. This book integrates fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It explores a wide range of topics that highlight the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhanci... strategies, and targeted therapies. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. Its distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research.

  • Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis

    • 1st Edition
    • Jyotsna Kailashiya
    • English
    Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis is a groundbreaking resource that delves into the impact of filarial parasites on platelet functions in humans. This comprehensive work explores the intricate signaling and immunological pathways affected by these interactions, filling a significant gap in the existing literature. The book is particularly valuable for researchers, scientists, and clinicians involved in the management and study of lymphatic filariasis, commonly known as elephantiasis; and also human platelets. With limited prior information on the interplay between human platelets and filarial parasites, this text offers a fresh perspective that could enhance patient management strategies. By understanding these interactions, healthcare professionals may unlock new avenues for effective treatment and prevention of lymphatic filariasis. This book is essential for anyone looking to deepen their understanding of the disease and contribute to its potential elimination.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 118
    • English
    Advances in Food and Nutrition Research, Volume 118 provides the latest advances on nanoformulations that can be used in the food industry, including chapters that cover important topics such as Nanoformulation Used In The Food Industry, Advances in Rapid On-Site Detection Techniques for Food Safety and Authenticity, Utilizing Artificial Intelligence to Enhance Sustainable High-Quality Food Production: Current State, Challenges, and Future Directions, Advances in High Hydrostatic Pressure Processing of Fruit and Vegetable Juicesm Functionality, Health Benefits, and Applications of Fish-Derived Hydrolysates and Peptides, and more.Additional chapters explore Maximizing the utilisation of seafood resources, A novel cooking technique for seafood: sous-vide, and Vegetable oils as a source of omega-3 fatty acids – transgenic vegetable oil.

  • Advances in Agronomy

    • 1st Edition
    • Volume 196
    • English
    Advances in Agronomy, Volume 196, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • ATP

    From Neurotransmission to Cancer Therapy
    • 1st Edition
    • Ronald Sluyter + 5 more
    • English
    ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the Molecular Mediators in Health and Disease series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond.

  • Marine Microbial Products

    Applications and Opportunities
    • 1st Edition
    • Sesan Abiodun Aransiola + 2 more
    • English
    Marine Microbial Products: Applications and Opportunities delves into the extensive world of marine microbes, an assemblage of organisms that contain a broad array of bioactive chemicals. Written and edited by a diverse team of environmental microbiologists, this book provides readers with a foundational understanding of marine microbial taxa, the products that may be synthesized from these organisms, technological innovations, and future directions of research. Chapters collate the most current research in healthcare, sustainability, and commercial production, presenting readers with the latest information on antibiotics, antivirals, anticancer therapeutics, immunosuppressive chemicals, bioremediation, food processing, biofertilizers, biopesticides, cosmetics, pigments, probiotics, and functional foods.The book is structured for accessibility to academic and professional audiences, spanning a variety of sectors. It is an indispensable resource for students, professors, researchers, and industry professionals in biology, biotechnology, sustainable development, food, healthcare sciences, and adjacent industries.

  • Immuno-oncology and Immunotherapy Part G

    • 1st Edition
    • Volume 202
    • English
    Immuno-oncology and Immunotherapy, Part G, Volume 202 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including In situ imaging of pulmonary invariant Natural Killer T cells in precision cut lung slices, Immunofluorescent microscopy to quantify and characterize chromosomal instability, Spatial techniques for understanding the tumor microenvironment, Very high-flex immunophenotyping using co-linear cytofluorometric evaluation, Large-scale CRISPR-Cas9 screens to define regulators of immune checkpoint biology, Assessment of cytoplasmic dsDNA for cellular immunogenicty, and much more.Additional sections cover Harmonization of a multiparametric flow cytometry panel for immunological monitoring on PBMC and whole blood samples: a real-life example, Quantitative assessment of arterial remodeling from confocal microscopy image analysis of the mid-gestation mouse decidua, Phenotypic characterization and function of tumor infiltrating and peripheral B cells in cancer patients, Methodological Advances to analyze Cancer-Associated Fibroblast-derived ECM effects on Macrophage Polarization, and many other topics that will be of interest to readers.

  • Endocrine and Metabolic Emergencies, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 55-1
    • George C. Willis + 1 more
    • English
    In this issue of Emergency Medicine Clinics, guest editors Drs. George Willis and Bennett A. Myers bring their considerable expertise to the topic of Endocrine and Metabolic Emergencies. Endocrine and metabolic emergencies, both those that are commonly encountered in day-to-day emergency medicine and those that are rarely seen, can result in serious complications that can be life-threatening if not recognized, diagnosed, and appropriately managed. In this issue, top experts in the field cover key topics such as diabetic ketoacidosis; hyperosmolar hyperglycemic state; disorders of sodium and potassium; hypoglycemia; and more.

  • Design and Applications of Cell-Free Systems Part B

    • 1st Edition
    • Volume 219
    • English
    Design and Applications of Cell-Free Systems, Part B, Volume 219 offers the latest information on cell free systems for the expression of transmembrane proteins, enzymes, proteins, therapeutics, vaccines, and uses in the biotransformation, translational modification, self-assembly of nano-biomaterials, and in synthetic biology design, challenges, and opportunities. It will help students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners understand cell-free systems and their applications in many areas. The book represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE).CFS requires core molecular machinery, including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins.

  • Tic Disorders and Tourette Syndrome

    • 1st Edition
    • Volume 215
    • Christos Ganos + 1 more
    • English
    Tic Disorders and Tourette Syndrome is an essential resource that delves into the clinical aspects, treatments, and ongoing research related to tic disorders and Tourette syndrome. It covers a range of topics from primary to secondary and functional tics, providing differential diagnosis. The book is designed to offer foundational knowledge to neurologists, psychiatrists, neuropsychiatrists, and psychologists, while also catering to the needs of advanced readers. In addition to clinical presentations, the book discusses the epidemiology, etiology, and pathophysiology of tics, along with common neuropsychiatric comorbidities such as obsessive-compulsive disorder, ADHD, mood disorders, and intermittent explosive disorder. The volume also includes treatment options and clinical scales to evaluate tics, illustrated with video accompaniments and animal models.

  • Handbook of Functional Foods

    Techniques, Analytics and Health Benefits
    • 1st Edition
    • Pradeep Kumar + 2 more
    • English
    Handbook of Functional Foods: Techniques, Analytics and Health Benefits provides a comprehensive overview of the extraction and analytical identification techniques of foods’ bioactive components for health and well-being while looking at metabolism, sensory, and safety components. This book reviews, in detail, how functional foods have the potential to drive innovation in the food industry, creating a broad range of healthier and more personalized food options. From emerging extraction and extrusion techniques for the creation of fiber-rich snacks to the synergistic effects of pro- and prebiotics on gut health, readers will come away with an advanced and fresh understanding of necessary insights.

  • Aquatic Waste Valorization

    Innovative Approaches and Sustainable Strategies
    • 1st Edition
    • Piyush Kashyap + 2 more
    • English
    Aquatic Waste Valorization: Innovative Approaches and Sustainable Strategies is a comprehensive guide for researchers and practitioners in food and environmental sciences, focusing on the critical intersection of waste management and sustainability within the aquatic food industry. The book explores the multifaceted dimensions of aquatic food industry waste, from its chemical composition and economic implications to a thorough introduction of valorization techniques for the use in functional food products and nutraceuticals. It covers emerging methodologies—includ... physical, chemical, and enzymatic processes—as well as approaches such as microbial conversion and nanotechnology, all aimed at transforming waste into valuable resources.In addition, it discusses the recovery of valuable components such as proteins, lipids, and bioactive compounds, highlighting their applications across various industries, including biofuels, bioplastics, and functional food ingredients. Through practical applications, it not only addresses the pressing issue of waste management but also presents innovative strategies to bolster both environmental and economic sustainability. Concluding sections examine global policies and regulations shaping the future of aquatic waste valorization.

  • Cushing Syndrome

    History, Diagnosis and Treatment
    • 1st Edition
    • Constantine A. Stratakis
    • English
    Cushing Syndrome: History, Diagnosis, and Treatment is written by top experts on the latest in genetics, molecular advances, and the diagnosis and treatment of Cushing syndrome. The book takes a historical approach to discuss the tremendous and unprecedented research development for this rare condition and includes information on recently approved treatments. It attempts to provide information on most issues surrounding Cushing syndrome and how to deal with its complications, the widening understanding of functional hypercortisolemia and other causes of endogenous cortisol production and its old and new treatment modalities, from pituitary to adrenal tumors, ectopic ACTH production, subclinical, cyclical Cushing syndrome, to aging and metabolic syndrome.The book has a section dedicated to our patients with the patients’ experiences, which will add to the outcome research presented by the physicians. This is a must have reference for scientists and researchers with the latest information in diagnosing and treating this difficult-to-diagnos... and difficult-to-treat condition and gives the clinician, a patient-centric approach to communicate with this particular group of patients.

  • Natural Product Drug Discovery

    Highly Anticipated Natural Molecules
    • 1st Edition
    • Ning Li + 1 more
    • English
    Natural Product Drug Discovery: Highly Anticipated Natural Molecules, a new volume in the Drug Discovery Opinion series, provides a comprehensive examination of the role of natural products in innovative drug development. The book addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. Sections present analyses of various classes of natural products, including polysaccharides, volatile oils, and diterpenoids, exploring their chemical properties, biological activities, and potential clinical applications. Each chapter, written by leading experts, offers insights into structural modification techniques, naturally sourced inhibitors, and the application of green biomanufacturing strategies.It will serve as an essential resource for researchers, pharmacologists, and industry professionals involved in natural product drug discovery. Readers will find the necessary information to navigate the complexities of the field, emphasizing the integration of traditional knowledge with modern scientific approaches. Through a thorough understanding of these natural compounds, this book aims to contribute to the advancement of therapeutic innovations in pharmacotherapy.

  • Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management

    • 1st Edition
    • Harish Dureja + 5 more
    • English
    Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies—inc... polymeric nanoparticles, liposomes, and theranostic nanoparticles—this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.

  • Molecular Horticulture & Advances in Production System Technology

    • 1st Edition
    • Volume 117
    • English
    This volume offers a comprehensive overview of cutting-edge developments in horticultural science. This authoritative collection features expert reviews on the molecular genetics and genomics of key species, including faba bean, tomato, celery, lily, and broccoli, elucidating the mechanisms behind yield, quality, and bioactive compounds. The volume also explores innovative and sustainable cultivation techniques, with in-depth analyses of controlled environment agriculture for leafy greens, the use of organic substrates, and the sensory implications of sustainable practices for Brassica oleracea. Crucial insights into the molecular control of pre- and post-harvest traits, this essential text provides researchers, students, and professionals with a forward-looking synthesis of modern horticultural science and its practical applications.

  • Antibiotic Resistance and Nanotherapy

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Antibiotic Resistance and Nanotherapy is a comprehensive guide that explores an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores the possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. This book also discusses the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, this book is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance.

  • Recent Advances in Bioelectromagnetism and Subtle Energies

    Implications for Health and Disease
    • 1st Edition
    • Jan Martel
    • English
    Recent Advances in Bioelectromagnetism and Subtle Energies: Implications for Health and Disease explores the new findings and emerging concepts in the fields of electromagnetism and human health. This book examines a range of topics from a biophysical and holistic perspective, including the effects of native and manmade electromagnetic fields on living organisms, the role of oxygen in cellular energy production, the intricacies of the human biofield, coherence in cellular and human health, quantum biology phenomena, the history and evolution of electrosensitivity, the development of electromagnetic hygiene, and promising healing modalities. Each chapter provides key insights about the biological effects of electromagnetic fields and their impact on human health and disease development, providing an ideal reference for scientists and readers interested in the recent advances in these areas.

  • Primary Aldosteronism: Physiopathology and Diagnosis

    • 1st Edition
    • Volume 130
    • English
    Primary Aldosteronism: Physiopathology and Diagnosis, Volume 130 focuses on the physiopathology and diagnosis of primary aldosteronism, covering some important topics such as Aldosterone: synthesis and regulation, Pathophysiology of primary aldosteronism, Prevalence of primary aldosteronism and screening indications, Clinical manifestations of primary aldosteronism and cardiometabolic risk, Diagnosis of primary aldosteronism: renin activity, renin concentration and aldosterone/renin ratio, Diagnosis of primary aldosteronism confirmatory test, Diagnosis of Primary Aldosteronism: Novel Workup Strategies and Biochemical Tools, and much more. Additional sections cover Genetics in primary aldosteronism, Low-renin hypertension, Adrenal venous sampling interpretation and other diagnostic lateralization tools in PA, and Aldosterona & Cortisol cosecretion.

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