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Books in Organic chemistry

This collection offers extensive coverage of organic synthesis, reaction mechanisms, and functional group chemistry. Showcasing innovative research, green chemistry approaches, and industrial applications, it supports chemists, students, and researchers in designing new molecules and materials. Addressing drug discovery, polymers, and sustainable processes, these titles foster creativity and technical excellence in advancing organic chemistry for societal benefit.

    • Glycosphingolipids in the Central Nervous System

      Diversity in Structure, Metabolism, Distribution, and Function
      • 1st Edition
      • Zhongwu Guo
      • English
      Glycosphingolipids in the Central Nervous System: Diversity in Structure, Metabolism, Distribution, and Function comprehensively covers progress made in the discovery, profiling and understanding of the metabolism, function and functional mechanism of GSLs in the CNS –as well as their synthesis, relationships with and therapeutic applications to neurodegenerative disorders, and related CNS diseases. Due to the important roles of GSLs in the CNS and various CNS-related diseases, the interest in these biomolecules is growing. GSLs are the principal glycolipids on the cell surface and an essential constituent of the cell membrane. They are widespread, but especially enriched in the central nervous system (CNS) in vertebrates. The diversity of GSL structures forges the molecular foundation for their broad spectrum of activity.
    • Studies in Natural Products Chemistry

      • 1st Edition
      • Volume 80
      • Atta-Ur Rahman
      • English
      Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.
    • Advances in Heterocyclic Chemistry

      • 1st Edition
      • Volume 143
      • English
      Advances in Heterocyclic Chemistry, Volume 143, the latest release in this esteemed series, highlights new advances in the field. Chapter sin this release include Heterocyclic Zwitterions Based on Coupled Polymethines, Recent chemistry and applications of 1,3,4-oxadiazoles, The Synthesis and Applications of Bioactive Phenoxazinones. Diversity of Heterocyclic Reactants in the Click Reaction, Recent advances in the Synthesis of Benzo[b]furans, Bis-ethanones and their derivatives: versatile precursors for bis-heterocycles.
    • Advances in Heterocyclic Chemistry

      • 1st Edition
      • Volume 142
      • English
      Advances in Heterocyclic Chemistry, Volume 142, the latest release in this definitive series, combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Chapters in this new release include Recent advances in the Synthesis of Benzo[b]furans, Recent Advances in the Synthesis of 6-Membered Heterocycles via Domino and Multicomponent Reactions (from 2017-2022), Multi-component synthesis of isatin based bioactive heterocycles, Recent advances in the chemistry of pyrazolo[1,5-a]pyrim... The Literature of Heterocyclic Chemistry, Part XXI, 2021, and much more.Additional sections present the latest Advances in applications of dihydropyridines in organic chemistry and Strategies for the annulation of five-membered sulfur-nitrogen rings to benzene and heterocycles.
    • Synthesis of Aziridines and Oxaziridines from Imines

      • 1st Edition
      • Navjeet Kaur
      • English
      Synthesis of Aziridines and Oxaziridines from Imines describes both new and old methods for the synthesis of aziridines from imines and covers an important and rapidly growing branch of heterocyclic chemistry. Readers will have access to different methods and information allowing them to evaluate which method is most suitable for particular cases. Several important advances in this area have been witnessed in recent years and discovering efficient novel methods for the synthesis of aziridines has been very active field of research. Its powerful synthetic utility has been described by an overpowering amount of documentation on the approaches for the formation of aziridine.The smallest possible saturated azaheterocycle, aziridine, is well-known to organic chemists for its tremendous potential in pharmaceutical chemistry and organic synthesis. The general biological importance of aziridines is proven by the fact that they found several uses as subunits in pharmacologically active compounds such as antitumor agents, enzyme inhibitors, and antibiotics. Although aziridines are highly reactive, this framework occurs in many synthetic compounds and the natural products of biological interest also contain aziridine skeleton in their structures.
    • Semisynthesis of Bioactive Compounds and their Biological Activities

      • 1st Edition
      • Sasadhar Majhi + 1 more
      • English
      Semisynthesis of Bioactive Compounds and their Biological Activities explores the potential benefits of semisynthetic derivatives obtained from nature. Sections cover the natural distribution of parent compounds, semisynthesis and biological properties of semisynthetic derivatives, the applications of semisynthetic derivatives in diverse fields such as drug delivery, food production and medicine, an explanation of the current resistance mechanisms of antibiotics, clinical applications of semisynthetic analogues, the functions of plant alkaloids on human health, potential agricultural biotechnology in semisynthetic derivatives, and semisynthesis of natural products under greener conditions, this book provides a comprehensive resource on the topics presented. Sections include information about alternative sources of energy and superior greener technologies (microwave, sonochemistry), alternative reaction media (water, supercritical CO2, ionic liquids) and alternative eco-friendly catalysts (biocatalysts). This book will be an excellent resource for academicians, researchers and students focusing on synthesis as well as the biological community and industry professionals in drug development.
    • Antidotes to Toxins and Drugs

      From Natural Sources to Drug Discovery in Toxicology
      • 1st Edition
      • Mihnea-Alexandru Găman + 1 more
      • English
      Antidotes to Toxins and Drugs: From Natural Sources to Drug Discovery in Toxicology presents recent advances in the discovery of natural antidotes to toxins, drug intoxications and overdoses in pharmacology, drug discovery and toxicology. The text provides detailed information about toxins and their natural antidotes, along with the identification and screening of antidotes for drug intoxications and overdoses. Written by a global team of experts, it describes the potential uses of natural products in toxicology and their applications in medicine and in the pharmaceutical sciences. This book will be a key resource for drug developers, medicinal chemists and toxicologists, among others.Sections shine a particular focus on mechanisms of action, various principles in pharmacokinetics and pharmacodynamics terms, and possible sources and synthesis techniques for these phytochemicals.
    • Natural Products as Anticancer Agents

      • 1st Edition
      • Bimal Krishna Banik + 1 more
      • English
      Natural Products as Anticancer Agents introduces the different types of natural products that have been used for cancer treatment. Divided into four parts, covering anticancer agents derived from terrestrial plants, anticancer agents derived from the marine environment, and anticancer agents derived from microorganisms, as well as evaluation of new anticancer agents, each part includes discussion of the properties, synthesis/extraction... storage, mechanism of action, and usage of the molecules. Discussion of the future prospects in anticancer natural products—including several new trends and an indication of where research in this area is likely to go in the future—is also included.
    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 62
      • Jonathan Bentley + 1 more
      • English
      Progress in Medicinal Chemistry, Volume 62 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.
    • Advances in Carbohydrate Chemistry and Biochemistry

      • 1st Edition
      • Volume 84
      • English
      Advances in Carbohydrate Chemistry and Biochemistry, Volume 84 in this series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.