Books in Life sciences

1761-1770 of 14816 results in All results

3D Bioprinting in Tissue and Organ Regeneration

1st Edition
September 10, 2022
Yang Wu + 2 more
English
Hardback
9 7 8 - 0 - 1 2 - 8 2 4 2 9 1 - 9
eBook
9 7 8 - 0 - 3 2 3 - 8 5 9 0 5 - 9

3D Bioprinting in Tissue and Organ Regeneration covers state-of-the-art advances and applications in bioprinting. Beginning with an introduction that considers techniques, bioinks and construct design, the authors then move onto a detailed review of applications of bioprinting in different biomedical fields (skin, cartilage, bone, vascularized tissue, etc.). This is followed by a chapter overview of intraoperative bioprinting, which is widely considered one of the important future trends in this area. Finally, the authors tackle ethical and regulation concerns regarding the utilization of bioprinting.The book is written by three global experts for an audience of students and professionals with some basic knowledge of bioprinting, but who seek a deeper understanding of the biomedical applications involved in bioprinting.

Phenotyping of Human iPSC-derived Neurons

1st Edition
September 9, 2022
Elizabeth D. Buttermore
English
Paperback
9 7 8 - 0 - 1 2 - 8 2 2 2 7 7 - 5
eBook
9 7 8 - 0 - 1 2 - 8 2 2 2 7 8 - 2

Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification.

Discoveries in Pharmacology - Volume 1 - Nervous System and Hormones

2nd Edition
September 9, 2022
Clive Page + 2 more
English
Hardback
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eBook
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Discoveries in Pharmacology: Volume 1: Nervous system and hormones (2nd Ed.) presents selected articles from the historic Discoveries in Pharmacology series enhanced with commentary from contemporary scholars about the reception and importance of the chapter along with an updated bibliography on the subject with contributions from a Nobel Prize winner and other pioneers in Pharmacology. The Discoveries in Pharmacology series brought acknowledged experts in their fields together to provide first-hand accounts of important pharmacological discoveries discussing the scientific background and stories behind these pivotal moments. They allow a true understanding of the means by which pharmacological discoveries are made. This volume brings forth discussions on key discoveries in psycho- and neuro-pharmacology, haemodynamics, and hormones including chapters on antipsychotic agents by Nobel winner Anders Carlsson, Willy Haefely on benzodiazepine, and butyrophenone-type neuroleptics by P. A. J. Janssen and J. P. Tollenaere. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area will find this series a useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

Quantum Mechanics, Cell-Cell Signaling, and Evolution

1st Edition
September 9, 2022
John S. Torday
English
Paperback
9 7 8 - 0 - 3 2 3 - 9 1 2 9 7 - 6
eBook
9 7 8 - 0 - 3 2 3 - 9 7 2 8 1 - 9

Quantum Mechanics, Cell-Cell Signaling, and Evolution offers a detailed accounting of the latest research and theorizing on the integration of quantum physics with biological action to produce a novel perspective on evolution. The book advocates for a paradigm shift towards understanding biology and medicine causally as predictive sciences, presenting quantum mechanics and physiology as vertically integrated. The author has taken a unique approach to the question of how and why evolution occurred. The account is based on extensive knowledge of lipid physical chemistry, and its role in the evolution of the lung under the influence of hormonal effects on structure and function. The title arranges lipid biochemistry and biophysics into an integrated explanation, guiding readers from the immersion of lipids in water as the origin of life, to lung surfactant in alveolar homeostasis, and leading to a new understanding of how consciousness interacts with the laws of nature. This volume argues for a novel understanding of evolutionary processes based on fundamental science and positions itself as seeking consilience among research disciplines. Starting from the origins of the cosmos, the author proceeds through nucleosynthesis and Endosymbiosis Theory, to finally describe consciousness in relation to natural law.

A Mathematical Approach to Special Relativity

1st Edition
September 9, 2022
Ahmad Shariati
English
Paperback
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eBook
9 7 8 - 0 - 3 2 3 - 9 9 7 0 9 - 6

A Mathematical Approach to Special Relativity introduces the mathematical formalisms of special and general relativity. Developed from the author’s experience teaching physics to students across all levels, the valuable resource introduces key concepts, building in complexity and using increasingly advanced mathematical tools as it progresses. Without assuming a background in calculus, the text begins with symmetry, before delving more deeply into Galilean relativity. Throughout, the book provides examples and useful "Guides to the Literature." This unique text emphasizes the experimental consequences and verifications of the underpinning theory in order to provide students with a solid foundation in this key area.

Advances in Genetics

1st Edition
Volume 109
September 9, 2022
Gerald R. Smith
English
Hardback
9 7 8 - 0 - 4 4 3 - 1 8 5 8 0 - 9
eBook
9 7 8 - 0 - 4 4 3 - 1 8 5 8 1 - 6

Advances in Genetics, Volume 109 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Epigenetic regulation of angiogenesis in tumor progression, RecBCD and Chi hotspots as determinants of self vs. non-self: A re-evaluation, Horizontal gene transfer to plants from Agrobacterium and related bacterial species, and more.

Asthma in the 21st Century

1st Edition
September 8, 2022
Rachel Nadif
English
Paperback
9 7 8 - 0 - 3 2 3 - 8 5 4 1 9 - 1
eBook
9 7 8 - 0 - 3 2 3 - 8 5 4 2 0 - 7

Asthma in the 21st Century: New Research Advances provides an overview on asthma, with discussions on its heterogeneity, risk factors and their interrelations, and e-health in an aging world based on current research knowledge. The book covers heterogeneity of the disease beyond severe asthma, new risk factors, new diagnoses with climate change, a focus on chemical exposures at home, e-health and links with aging, and notable advances in key areas such as diet and microbiota, the genetics of asthma, and the asthma versus COPD debate. Worldwide, the total number of asthma sufferers is estimated to be ~270 million with an additional 100 million expected to develop asthma by 2025, and asthma is the most common chronic disease among children. There are a number of clinical books available on asthma, but none with much discussion on current scientific findings and new disease understanding. Yet, the concept of asthma has evolved quickly in the past 5–10 years, with many clinicians struggling to keep up with new scientific findings.

Plasma Membrane Shaping

1st Edition
September 8, 2022
Shiro Suetsugu
English
Paperback
9 7 8 - 0 - 3 2 3 - 8 9 9 1 1 - 6
eBook
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Plasma Membrane Shaping summarizes current knowledge on how cells shape their membrane. Organized in four sections, the book opens with a broad overview of the plasma membrane, its composition, usual shapes and substructures, Actin/WASP/arp2/3 structures, BAR domains, and Ankyrin repeat domains, dynamin, and phospholipid signaling. Other sections cover the shaping of the plasma membrane for transport processes, discussions on exosomes, microvesicles, and endosomes, clathrin-coated pits, caveolae, and other endocytic pits, membrane deformation for cell movement, and some of the most current dry and wet lab research techniques to investigate cellular membrane shaping. This is an ideal resource for new researchers coming into this area as well as for graduate students. The methods section will be of interest to both microscopists and computer scientists dedicated to the visualization, data collection, and analysis of plasma membrane shaping experiments.

Handbook of Epigenetics

3rd Edition
September 8, 2022
Trygve O Tollefsbol
English
Hardback
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eBook
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Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related diseases, transposable elements and epigenetics, X chromosome inactivation, and the epigenetics of drug addiction, among other topics. Throughout this edition, greater emphasis falls on epigenomic analyses and incorporating multi-omics approaches rather than gene-specific analyses. In addition, this edition has also been enhanced with step-by-step instructions in research methods, as well as easy-to-digest disease case studies and clinical trials that provide context and applied examples of recent advances in disease understanding and epigenetic therapeutics. These features empower researchers to reproduce the approaches and studies discussed and aid clinical translation. Live links across chapters tie in relevant external datasets and resources.

Advances in Automated Diagnosis of Intestinal Parasites of Animals and Humans

1st Edition
Volume 118
September 8, 2022
Laura Rinaldi + 1 more
English
Hardback
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eBook
9 7 8 - 0 - 3 2 3 - 9 9 4 0 4 - 0

Advances in Parasitology, Volume 116, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Landscape analysis of available diagnostic tests for STH: how far are we from the WHO TPPS? and Challenges and solutions for the diagnosis of animal and human Strongyloides stercoralis infection.

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