Translational research is essential to the advancement of medicine. Translational Pulmonology is an instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in pulmonary diseases, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.
Heart Failure in the Child and Young Adult: From Bench to Bedside, Second Edition highlights unique aspects of heart failure in the young. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure and then progresses through diagnosis, management, treatment, and surgery, finally concluding with advanced special topics, including genetics, self-management, and nanomedicine.This new edition covers advancements in the field, including additional chapters and discussion on biomarkers, neuromuscular disease, quality of life, palliative care, and the impact of COVID-19 in myocarditis and multisystem inflammatory syndrome in children. It will serve as an indispensable reference to basic science researchers in cardiology, pediatrics, cardiologists, and pediatric cardiologists.
Mixed crop-livestock systems offer promising strategies for sustainable farming. Innovations for Sustainable Agriculture: From Lab to Farm to Table details solutions for mitigating agricultural waste, such as carbon emissions and chemical runoff, and creating a circular economy on mixed farms. In addition to covering potential solutions, the book will analyze the effectiveness of each strategy in protecting the environment from harm. Notable topics covered include manure management, agricultural waste valorization, wastewater and resource recovery, and even dairy cow feed for lowering methane production.While the book is based primarily on the climates and farming systems of Europe, the climactic diversity of the continent will make this a useful resource for many other parts of the world with similar climates, including North America and portions of South America, Asia, and Oceana. Innovations for Sustainable Agriculture: From Lab to Farm to Table offers practical strategies and solutions to readers and will benefit audience members ranging from students and researchers to farmers and agricultural stakeholders.
Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part B, Volume 392 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Circulating Tumor Cells in Lung Cancer: integrating stemness and heterogeneity to improve clinical utility, Multi-omic Features and Clustering Phenotypes of Circulating Tumor Cells Associated with Metastasis and Clinical Outcomes, CTCs in CRC: updates, Proteomics and post-translational modification analysis in CTCs, Latest advances of CTC studies in prostate cancer, and Epigenetics and CTCs: new biomarkers and impact on tumor biology.
Handbook of Robotic and Image-Guided Surgery, Second Edition provides an update on state-of-the-art systems and methods for robotic and computer-assisted surgeries. Written by leading researchers from academia and industry, this new edition includes over 700 illustrations, flowcharts, diagrams, and dedicated multimedia content across all chapters.This new edition also includes introductory chapters which discuss the fundamental concepts in robotics and image-guided surgery. Through its coverage of basic concepts and recent advances across all subspecialties, the book serves as a vital and comprehensive reference for engineers, surgeons, and researchers in the life science and healthcare world interested in surgical robotics.Fusing engineering, radiology, and surgical principles into one book, this new edition also includes coverage of new surgical devices and new surgical robotic systems, expanding the number of chapters from 39 to more than 50. Biomedical engineers, mechanical engineers, electrical and computer engineers, medical and engineering students, and surgeons in the field of surgical robotics and image-guided surgery will benefit from this comprehensive reference, written by global experts from across academia and industry.
Techniques and Protocols in Molecular Biology delivers detailed practical guidance for a variety of molecular techniques and procedures. Each chapter focuses on a different technique, including isolation techniques for DNA and RNA, gene cloning, PCR, DNA sequencing, ELISA and cell culture. These protocols all includes a detailed description of the technique along with the main principles, required equipment, and comprehensive steps to assist researchers with replicating the protocol and performing the techniques themselves.This foundational reference is essential for students and researchers looking to enhance their understanding of key molecular techniques and reproduce them successfully in their own laboratory work.
Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.
The Organic Chemistry of Drug Design and Drug Action, Fourth Edition presents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action. The book's coverage allows readers to extrapolate core principles and mechanisms to many related classes of drug molecules. It reflects the significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while also including significant changes in format and coverage.It is designed for undergraduate and graduate students in chemistry who are studying medicinal chemistry or pharmaceutical chemistry. Users, including research chemists and biochemists working in pharmaceutical and biotechnology industries will find this update to be useful in their daily work.
Pediatric and Adolescent Gynecologic Surgery: Management, Surgical Approaches, and Post-Operative Care is an excellent and novel resource to understanding the management of adolescent gynecologic patients as written by top experts. The book offers detailed pearls of surgery and has a preoperative planning approach to abdominal, laparoscopic, and vaginal surgeries, as well as postoperative considerations. This is a comprehensive but easy-to-follow step-by-step surgical atlas for PAG surgeries organized in a historical context with the most recent research advances in the field. It provides expert views and perspectives with visuals to aid in learning useful to anyone in, or interested in, the field.
Culinary Nutrition: The Science and Practice of Healthy Cooking, Second Edition is one of the first textbooks specifically written to bridge the relationship between food science, nutrition, and culinology as well as consumer choices for diet, health, and enjoyment. The book uses a comprehensive format with real-life applications, recipes, and color photographs of finished dishes to emphasize the necessity of sustainably deliverable, health-beneficial, and taste-desirable products.The book includes pedagogical elements to enhance and reinforce learning opportunities; explores which foods and beverages involve the optimum nutritional values for dietary and health needs; includes specific dietary requirements throughout the lifecycle; and examines how foods and beverages are produced. The fully revised second edition includes updated dietary and health guidelines and recommendations; more vegan, vegetarian, and plant-based meals; updated protein, carbohydrate, fat, vitamin and mineral recommendations; environmental and sustainability considerations; and much more.