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Elsevier

Books in Life sciences

  • Biomarkers of Hip Implant Function

    • 1st Edition
    • Ilona Swiatkowska
    • English
    Nearly all orthopaedic surgeons have implanted a cobalt-chromium hip, and most general practitioners have at least one patient with a cobalt-chromium prosthesis on their books. The recent worldwide controversy surrounding metal-on-metal bearings – and increasing concern over the use of metallic biomaterials in general – means that advice on how to manage patients with metal implants is of great interest to these professionals. Specifically, they want to know if there are any diagnostic tests that could be performed to gain clues about implant performance and the risk of local or systemic toxicity. Biomarkers of Hip Implant Function aims to bring together all established and promising new biomarkers and critically evaluate their clinical usefulness. Researchers will benefit from an updated, comprehensive view of the topic to identify underexplored areas. Orthopaedic surgeons and general practitioners will use the book to monitor implant performance and manage their patients. The work may also benefit engineers and joint implant manufacturers by guiding improvements in implant design, and be of interest to regulators and policymakers to inform guidelines on the follow-up of hip implant recipients.

  • Nanotechnology for Drug Delivery and Pharmaceuticals

    • 1st Edition
    • Ravindra Pratap Singh + 3 more
    • English
    Nanotechnology for Drug Delivery and Pharmaceutical Sciences presents various drug-delivery techniques that utilize nanotechnology for the biomedical domain, highlighting both therapeutic and diagnostic applications. The book provides important facts and detailed studies on different promising nanocarriers like liposomes, exosomes and virus-based nanocarriers. Moreover, it explores these nanocarriers' utilization in the therapeutic applications of various diseases such as cancer, inflammation, neurodegenerative disorders like Huntington’s disease, Alzheimer's disease, human immunodeficiency virus (HIV), and inflammatory bowel disease. In addition, the book describes how nanotechnology has efficiently overtaken conventional dosage forms and provided comfort and ease to patients. Relevant information regarding market trends, patents and social-economic factors are also provided, making this the perfect reference for doctors, researchers and scientists working in the fields of medicine, biochemistry, biotechnology, nanobiotechnology and the pharmaceutical sciences.

  • Advances in Agronomy

    • 1st Edition
    • Volume 177
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 117, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Chapters in this new release include Farming Systems Research: Concepts, Design and Methodology, Soil Potassium Fertility and Management Strategies in South Asian Agriculture, Sensing for Characterizing and Monitoring Soil Functions – A Review, Isolation and Fractionation of Organic Matter from Soils and Waters, Tolerance Mechanism and Management Concepts of Iron Toxicity in Rice: A Critical Review, and Smart Sensing and Automated Irrigation for Sustainable Rice Systems: A State of the Art Review.

  • Encyclopedia of Sleep and Circadian Rhythms

    • 2nd Edition
    • Clete Kushida
    • English
    Encyclopedia of Sleep and Circadian Rhythms, Second Edition, Six Volume Set is the most comprehensive work on sleep and circadian rhythms. This completely revised new edition, comprised of contributions from 450 renowned authorities in the field, covers what is new and known in the field. In addition to thorough coverage of the basics (physiology, sleep disorders etc.), this new edition includes a thorough examination of circadian rhythms that manage the sleep-wake cycle. Although this area is highly intertwined with sleep, it is a scientific discipline in and of itself, and will broaden the appeal of this work to health care providers and scientists. Other sections of interest explore consumer wearable devices to track sleep and circadian rhythms, artificial intelligence algorithms to detect sleep and abnormal sleep-related conditions, and new technology to treat sleep and circadian rhythm disorders. This book will be an ideal and primary reference resource for students, trainees, technologists, basic/clinical scientists, physicians, advanced practice providers, psychologists, nurses, and other medical and research personnel who want to explore any topic within the sleep and circadian rhythm field.

  • Receptor Endocytosis and Signalling in Health and Disease - Part A

    • 1st Edition
    • Volume 194
    • English
    Receptor Endocytosis and Signalling in Health and Disease, Volume 194 in the Progress in Molecular Biology and Translational Science, highlights new advances in the field. Chapters in this release include An overview on receptor endocytosis and signaling, Signaling molecules: Importance in health and disease conditions, Emerging tools for studying of receptor endocytosis and signaling, Endocytosis of EGFR: Signalling in cancer, Endocytosis of AT1 and AT2 receptors: Signalling in the kidney, Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants, Endocytosis of Insulin receptor: Signalling in the regulation of glucose homeostasis, Endocytosis of VEGFR: Role in the regulation of angiogenesis, and more. Other sections in this new release include Lymphocyte and monocyte/macrophage receptors mediating immune recognition of tumors, Lymphocyte and monocyte/macrophage receptors triggering immune suppression of tumor immunity, Prion receptors and prion internalization and intra- and inter-cellular transport, Multifunctional role of the ubiquitin proteasome pathway in phagocytosis, Adrenoceptors and SCD1 in adipocytes/adipose tissues: the expression and variation in health and obesity, Frizzled receptors and SFRP5 in lipid metabolism: current findings and potential applications.

  • Ticks

    Biology, Ecology, and Diseases
    • 1st Edition
    • Nicholas Johnson
    • English
    Ticks: Biology, Ecology and Diseases provides a detailed overview of the fascinating world of tick biology and ecology. This book discusses disease transmission to humans and livestock, assesses the impact of human behavior and climate change on tick biology, and details how this will affect future disease transmission. Written by an expert on ticks and their transmitted diseases, this book explores the unique biology of ticks and how it influences the transmission of some of the most devastating diseases. In a series of detailed chapters, the book provides up-to-date information on the interrelationship between ticks and the vertebrates they feed on. In addition, the book covers information on recent scientific discoveries surrounding ticks, along with reviews on control methods and disease transmission. Other sections cover the recent emergence of tick-borne pathogens, making this book an ideal source for interested scientists, clinicians, veterinarians and experts in the field of tick biology.

  • Advances in Epidemiological Modeling and Control of Viruses

    • 1st Edition
    • Hemen Dutta + 1 more
    • English
    Advances in Epidemiological Modeling and Control of Viruses covers recent and advanced research works in the field of epidemiological modeling, with special emphasis on new strategies to control the occurrence and reoccurrence of viruses. The models included in this book can be used to study the dynamics of different viruses, searching for control measures, and epidemic models under various effects and environments. This book covers different models and methods of modeling, including data-driven approaches. The authors and editors are experienced researchers, and each chapter has been designed to provide readers with leading-edge information on topics discussed.

  • Biosurfactants

    Research and Development
    • 1st Edition
    • Gloria Soberon-Chavez
    • English
    Biosurfactants: Research and Development provides a thorough overview of biosurfactant research and development across a range of settings and industries, highlighting the novel use of enzymes, metabolic and genetic engineering in biosurfactant production and showcasing diverse experimental models and approaches. Sections discuss fundamental characteristics of biosurfactants, their physio-chemical properties, and their differences from chemically synthesize surfactants, different research approaches for the study of known biosurfactants, and the genetic manipulation of microorganisms to increase biosurfactant productivity, or to produce molecules with improved characteristics. Throughout the book, methods and approaches are discussed in easy-to-digest formats, with methods discussed, ranging from in silico approaches to classical biocatalysis omics analysis and metabolic engineering.

  • Smartphone Apps for Health and Wellness

    • 1st Edition
    • John Higgins + 1 more
    • English
    Smartphone Apps for Health and Wellness helps readers navigate the world of smartphone apps to direct them to those which have had the best medical evidence in obtaining the users’ goal. The book covers the history of apps, how they work, and specific apps to improve health and wellness in order to improve patients outcomes. It discusses several types of apps, including apps for medical care, sleeping, relaxation, nutrition, exercise and weight loss. In addition, sections present the features of a good app to empower readers to make their own decision when evaluating which one to use. This is a valuable resource for clinicians, physicians, researchers and members of biomedical field who are interested in taking advantage of smartphone apps to improve overall health and wellness of patients.

  • Emerging Technologies in Applied and Environmental Microbiology

    • 1st Edition
    • Maulin P. Shah + 1 more
    • English
    Emerging Technologies in Applied and Environmental Microbiology describes various problems and solutions that arise in applied and environmental microbiology using scientific technologies. The book summarizes the main omic-based methods currently used to characterize environmental microorganisms, as well as approaches to analyzing and interpreting the bio information generated by experimentally based studies. Sections explore the current understanding of bacterial signaling through examples of communication systems that include signaling in gram-positive and gram-negative bacteria, along with discussions on how microorganisms interact with each other, with other organisms, and with the environment. In addition, this comprehensive resource highlights the importance of various emerging technologies for cleaning up pollution in the environment caused by human activities. Final sections assess the potential application of several existing, applied and environmental microbiological techniques and introduces new and emerging technologies through applied aspects.

  • Dysphagia

    Diagnosis and Treatment of Esophageal Motility Disorders
    • 1st Edition
    • Marco G. Patti + 2 more
    • English
    Dysphagia: Diagnosis and Treatment of Esophageal Motility Disorders provides a interdisciplinary overview of the diagnosis and management of dysphagia and other esophageal symptoms. All aspects of dysphagia are covered, with detailed consideration of both physiology and evaluation methods. Hot topics include coverage on the pharmacological causes of dysphagia, the physiology of normal swallowing, ambulatory pH monitoring as well as recurrent dysphagia after treatments. The content is grounded in evidence-based medicine that is the result of clinical outcome research, both prospective and randomized, making this the perfect reference for clinical researchers and a go-to for general surgeons, foreguts surgeons, thoracic surgeons and gastroenterologists.

  • A Clinical Guide to Inositols

    • 1st Edition
    • Vittorio Unfer + 1 more
    • English
    A growing body of research demonstrates the potential benefits of the administration of inositol isomers in the treatment of many different disorders, from reproductive to metabolic diseases.A Clinical Guide to Inositols discusses scientific evidence of inositol-based treatments in different clinical fields to provide clinicians with a practical guide to use inositol supplementation within pathological conditions. Each chapter covers a specific disorder and describes aspects of the application of inositol in clinical practice, discussing the physio-pathologic features of the health condition and scientific evidences of the effects of inositol treatment.This book is a valuable resource to researchers and clinicians looking for a clear understanding of clinical effects of inositol supplementation and a practical guide on inositol-based treatments.

  • Neuropalliative Care

    Part II
    • 1st Edition
    • Volume 191
    • English
    Neuropalliative Care, Part Two, Volume 191 covers a type of care that is given when there is no cure for the neurological disorder and the patient is in distress. It provides a scholarly background of neuropalliative care, from historic underpinnings to its practice in various geographical regions, along with best practices for specific neurological disorders. It covers the work of multi or interdisciplinary teams whose care is intended to make the patient as comfortable as possible and includes partners and families in treatment plans.

  • Quick Guide to Body Fluid Testing

    • 2nd Edition
    • Darci R. Block + 1 more
    • English
    Quick Guide to Body Fluid Testing, Second Edition comprehensively covers the latest updates in three parts devoted to preanalytic considerations such as collection, labeling, handling, transport, specimen pretreatment, test ordering practices, analytic validation and postanalytic considerations. This revised edition includes a new section on validation requirements when replacing instruments, expanded post-analytical considerations to include selection of quality control materials and concentrations, and expanded frequently asked questions to address questions that arise around body fluid testing. This second edition aims to help laboratories make decisions about their body fluid testing menu and risk-based decisions about the thoroughness of their validation study design, making it a valuable resource to lab professionals. This book will act as a readily available pocket reference for students, academics and health care professionals working in a wide variety of contexts in the body fluid testing process.

  • Cell Biology

    • 4th Edition
    • Thomas D. Pollard + 3 more
    • English
    **Selected for 2026 Doody's Core Titles as an Essential Purchase in Cell Biology/Histology**R... Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods—from single cell RNA sequencing to second generation super resolution fluorescence microscopy—on advancing our understanding.

  • Marschner's Mineral Nutrition of Plants

    • 4th Edition
    • Zed Rengel + 2 more
    • English
    An understanding of the mineral nutrition of plants is of fundamental importance in both basic and applied plant sciences. The fourth edition of this book retains the aim of the first in presenting the principles of mineral nutrition in the light of current advances. Marschner's Mineral Nutrition of Plants, 4th Edition, is divided into two parts: Nutritional Physiology and Plant–Soil Relationships. In Part I, emphasis is put on uptake and transport of nutrients in plants, root–shoot interactions, role of mineral nutrition in yield formation, stress physiology, water relations, functions of mineral nutrients and contribution of plant nutrition to food nutritional quality, disease tolerance, and global nutritional security of human populations. In view of the increasing interest in plant–soil interactions. Part II focuses on the effects of external and internal factors on root growth, rhizosphere chemistry and biology, soil-borne ion toxicities, and nutrient cycling. Now with color figures throughout, this book continues to be a valuable reference for plant and soil scientists and undergraduate and graduate students in the fields of plant nutrition, nutritional physiology, and soil fertility.

  • Primer on the Autonomic Nervous System

    • 4th Edition
    • Italo Biaggioni + 5 more
    • English
    Primer on the Autonomic Nervous System, Fourth Edition provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book's 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored.

  • Anti-Aging Pharmacology

    • 1st Edition
    • Vitaly Koltover
    • English
    **Association of American Publishers (AAP) PROSE Award Finalist in Clinical Medicine, 2024**Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm.This book contains the work of the world’s leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice.

  • NK Cells in Cancer Immunotherapy: Successes and Challenges

    • 1st Edition
    • Volume 4
    • Anahid Jewett + 1 more
    • English
    NK Cells in Cancer Immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies, focusing on NK cells to allow the best and precise combination treatments to cancer patients. The book provides existing background knowledge in the field of immunotherapy and discusses future areas of research required to carry out cutting-edge, validated therapies. Chapters cover advances in immunotherapeutic strategies, in particular, the use of NK cells with and without T-cell therapy in the treatment of cancer. The book is a valuable resource for cancer researchers, oncologists, graduate students and those interested in learning more about novel strategies to treat cancer patients. Immunotherapy is fast becoming the method of choice for cancer therapy. Although remarkable advances have been made in the field of immunotherapy, there are significant challenges and difficulties ahead since many of the current immunotherapeutic strategies do not provide long-lasting treatment strategies, and therefore are not very effective.

  • GMOs and Political Stance

    Global GMO Regulation, Certification, Labeling, and Consumer Preferences
    • 1st Edition
    • Muhammad Amjad Nawaz + 3 more
    • English
    GMOS and Political Stance: Global GMO Regulation, Certification, Labeling, and Consumer Preferences provides a foundational-to-curr... challenges resource for those involved in developing and applying regulations to these important resources. Beginning with basics of GMOs, the book first familiarizes the reader with the history, economic status, associated risks, global politics, and socio-economics of GMOs. From exploring the necessity of GMO regulations with the existing GMO technology as well as new gene editing technologies to discussion by GMO regulations experts from different continents and countries, readers will find the information necessary to understand the laws, rules, regulations and policies at domestic and international scale. A last chapter delivers an update and future look on gene-edited food and feed and discusses the possibilities on the future risk assessment, legislation and regulation of gene-edited products. GMOS and Political Stance provides a unique and applicable synchronization of all regulatory information on GMOs to facilitate effective and efficient regulatory development and adherence.

  • Plant Stress Mitigators

    Types, Techniques and Functions
    • 1st Edition
    • Mansour Ghorbanpour + 1 more
    • English
    Plant Stress Mitigators: Types, Techniques and Functions presents a detailed contextual discussion of various stressors on plant health and yield, with accompanying insights into options for limiting impacts using chemical elicitors, bio-stimulants, breeding techniques and agronomical techniques such as seed priming, cold plasma treatment, and nanotechnology, amongst others. The book explores the various action mechanisms for enhancing plant growth and stress tolerance capacity, including nutrient solubilizing and mobilizing, biocontrol activity against plant pathogens, phytohormone production, soil conditioners, and many more unrevealed mechanisms. This book combines research, methods, opinion, perspectives and reviews, dissecting the stress alleviation action of different plant stress mitigators on crops grown under optimal and sub-optimal growing conditions (abiotic and biotic stresses).

  • The Plant Hormone Ethylene

    Stress Acclimation and Agricultural Applications
    • 1st Edition
    • Antonio Ferrante + 2 more
    • English
    The Plant Hormone Ethylene: Stress Acclimation and Agricultural Applications presents current knowledge on our understanding of ethylene perception and signaling, its role in the regulation of plant physiological processes, and its contribution to acclimation in stressful environments. Plants regularly face environmental constraints due to their immobile nature. In persistently changing environmental conditions, several stress factors influence cellular metabolism, ultimately causing reduced plant growth and development with a significant loss in agricultural productivity. Sustainable agriculture depends on the acclimation of plant processes to the changing environment through altered physiological and molecular responses, which are controlled by plant hormones, including ethylene. Ethylene interacts with other plant hormones and signaling molecules to regulate several cellular processes, plant growth and development, and, ultimately, crop productivity. This book begins with an introduction to ethylene before providing a detailed study of the latest findings on the role of ethylene in plants, including its role in photosynthetic processes, flower development, leaf senescence, nutrients acquisition, and regulation of abiotic stress responses as well as its application in agriculture. The book is an ideal guide for researchers exploring plant physiology and biochemistry as well as for those investigating the use of ethylene knowledge in agriculture in persistently changing environmental conditions.

  • Handbook of Lifespan Cognitive Behavioral Therapy

    Childhood, Adolescence, Pregnancy, Adulthood, and Aging
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Mental illness and the variety of conditions, disorders, and phobias associated with it impact not only the individual but also the family unit, the community, and society at large. Handbook of Cognitive Behavioral Therapy by Disorder: Case Studies and Application for Adults will better readers’ understanding of a variety of these conditions in adults specifically and the applicability of CBT therapy as a treatment. Featuring chapters on schizophrenia, bipolar disorder, dysmorphia, depression, and anxiety, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues in adults. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

  • Foot and Ankle Biomechanics

    • 1st Edition
    • William Ledoux + 1 more
    • English
    Foot and Ankle Biomechanics is a one source, comprehensive and modern reference regarding foot and ankle biomechanics. This text serves as both a master reference for foot biomechanics, presenting a clear state of the research and capabilities in the field. The customers for this book will be those looking for information on foot and ankle biomechanics for a range of applications; for example, designers of orthotics.

  • Handbook of Cognitive Behavioral Therapy by Disorder

    Case Studies and Application for Adults
    • 1st Edition
    • Colin R. Martin + 2 more
    • English
    Pregnancy, childbirth, childhood, adolescence, and aging can be beset with adverse changes in psychobiology and behavior. Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging will better readers’ understanding of a variety of conditions and the applicability of CBT therapy as a treatment. Featuring chapters on postnatal anxiety and depression, insomnia, and dysmorphia, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues affecting individuals at the start and end of their lives. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

  • Marine Antioxidants

    Preparations, Syntheses, and Applications
    • 1st Edition
    • Se-Kwon Kim + 2 more
    • English
    Marine Antioxidants: Preparations, Syntheses, and Applications provides the most updated and comprehensive knowledge on utilizing marine-derived substances for cosmeceutical, pharmaceutical and nutraceutical developments. The book delivers the isolation procedures and biological activity of marine-derived antioxidant substances as discussed by international experts on antioxidant material from actinobacteria, crustaceans, diatoms, fish, microalgae, microbes, and mangrove-associated marine organisms and seagrasses. In addition, the book details marine-derived bioactive antioxidants substances in the form of proteins, peptides, polysaccharides and lipids. Finally, the book provides the latest information on the mechanistic pathways of antioxidant substances with various diseases and nutritional perspectives. This is an essential resource for marine biotechnologists and marine biologists who want to better understand isolation procedures and antioxidant applications. Researchers interested in pharmaceutical nutrients, polymer science, and cosmeceuticals industries scientists, as well as students and academics, will also benefit from this book.

  • Determinants of Addiction

    Neurobiological, Behavioral, Cognitive, and Sociocultural Factors
    • 1st Edition
    • Justin R. Yates
    • English
    Why can two people use a drug and one person becomes addicted while the other does not? Determinants of Addiction: Neurobiological, Behavioral, Cognitive, and Sociocultural Factors unravels the complexities underlying addiction to understand how individual factors at the genetic, cellular, anatomical, cognitive–behavioral... and sociocultural level can influence susceptibility to substance use disorders. The first section reviews the neurobiological determinants of addiction and examines how drugs hijack the reward pathway and alter numerous neurotransmitter systems such as dopamine. The second section covers the behavioral–cognitive determinants of addiction such a conditioning, memory processes, and decision-making. The final section examines individual differences in addiction vulnerability, with a focus on personality factors, sociocultural factors, sex/gender, and stress. The book references commonly used drugs such as nicotine, ethanol (alcohol), opioids, and cocaine.

  • Autoimmunity, COVID-19, Post-COVID19 Syndrome and COVID-19 Vaccination

    • 1st Edition
    • Volume 1
    • Yehuda Shoenfeld + 1 more
    • English
    Autoimmunity, COVID-19, Post-COVID-19 Syndrome and COVID-19 Vaccination covers all aspects of what is perhaps the most dramatic health crisis in the history of modern medicine. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raised major concerns about the association between the virus and various autoimmune manifestations. Over 15 distinct autoantibodies and above 10 different autoimmune diseases were found to develop in COVID-19 patients. Moreover, evidence about recovered COVID-19 patients demonstrates that persistent systemic symptoms, which are believed to have an autoimmune-related mechanism, do exist. As it is of great importance to recognize those autoimmune manifestations of COVID-19 and post-COVID-19 syndrome to properly cope with their outcomes in the ongoing pandemic and the long-term post-pandemic period, this book fulfills a vital need in the medical community.

  • Urban and Regional Agriculture

    Building Resilient Food Systems
    • 1st Edition
    • Peter Droege
    • English
    Urban and Regional Agriculture: Building Resilient Food Systems explores the sustainable integration of food provision, distribution and consumption through urban farms, agricultural systems, user communities and structural facilities designed to optimize food production and consumption. The book addresses the fundamental and pressing challenges of urban planning problems, waste minimization, food sourcing, access and equity issues, and multiple land use optimization. Sections cover the need and opportunities of urban agriculture, discuss tradition and transition, space and regulatory topics, explore the range of urban agriculture options (aquaculture to urban permaculture), discuss support structures and constructs of physically creating urban agricultural areas, and much more. Edited and authored by leading experts in the field, this volume will be valuable for those working to address issues of food security in urban environments.

  • Functional Foods and their Implications for Health Promotion

    • 1st Edition
    • Ioannis Zabetakis + 3 more
    • English
    Functional Foods and Their Implications for Health Promotion presents functional foods, from raw ingredients to the final product, providing a detailed explanation on how these foods work and an overview of their impact on health. The book presents the functions of food against disease and discusses how healthier foods can be produced. Broken into four parts, the book presents a deep dive into plant-derived functional foods, dairy foods, marine food and beverages. The book includes case studies, applications, literature reviews and coverage of recent developments.Intende... for nutritionists, dieticians, food technologists, as well as students and researchers working in nutrition, dietetics, and food science, this book is sure to be a welcomed resource.

  • Epigenetics in Organ Specific Disorders

    • 1st Edition
    • Volume 34
    • English
    **Selected for Doody’s Core Titles® 2024 in Clinical Genetics**Epigenetic... in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth.Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.

  • Perinatal and Developmental Epigenetics

    • 1st Edition
    • Volume 35
    • Garima Singh
    • English
    Perinatal and Developmental Epigenetics, Volume 32, a new volume in the Translational Epigenetics series, provides a thorough overview of epigenetics in the early developmental and perinatal stages, illuminating pathways for drug discovery and clinical advances. Here, over 25 international researchers examine recent steps forward in our understanding of epigenetic programming during perinatal and early development. The book opens with an in-depth introduction to known and newly discovered epigenetic marks and how they regulate various cellular processes. Later sections examine various prenatal and perinatal environmental experiences and their ability to derail the normal developmental trajectory via epigenetic reprogramming. Insights and suggestions for future research illuminate approaches for identifying individual disease susceptibility. Concluding chapters highlight preventative and targeted therapeutic pathways to improve quality of life into adulthood.

  • Biomedical Defense Principles to Counter DNA Deep Hacking

    • 1st Edition
    • Rocky Termanini
    • English
    Biomedical Defense Principles to Counter DNA Deep Hacking presents readers with a comprehensive look at the emerging threat of DNA hacking. Dr. Rocky Termanini goes in-depth to uncover the erupting technology being developed by a new generation of savvy bio-hackers who have skills and expertise in biomedical engineering and bioinformatics. The book covers the use of tools such as CRISPR for malicious purposes, which has led agencies such as the U.S. Office of the Director of National Intelligence to add gene editing to its annual list of threats posed by "weapons of mass destruction and proliferation." Readers will learn about the methods and possible effects of bio-hacking attacks, and, in turn the best methods of autonomic and cognitive defense strategies to detect, capture, analyze, and neutralize DNA bio-hacking attacks, including the versatile DNA symmetrical AI Cognitive Defense System (ACDS). DNA bio-hackers plan to destroy, distort and contaminate confidential, healthy DNA records and potentially create corrupted genes for erroneous diagnosis of illnesses, disease genesis and even wrong DNA fingerprinting for criminal forensics investigations.

  • Microbial Biomolecules

    Emerging Approach in Agriculture, Pharmaceuticals and Environment Management
    • 1st Edition
    • Ajay Kumar + 3 more
    • English
    Microbial Biomolecules: Emerging Approach in Agriculture, Pharmaceuticals and Environment Management explores and compiles new aspects of microbial-based biomolecules such as microbial enzymes, microbial metabolites, microbial surfactants, exopolysaccharides, and bioactive compounds and their potential applications in the field of health-related issues, sustainable agriculture and environment contamination management. Written for researchers, scientists, and graduate and PhD students in the areas of Microbiology, Biotechnology, Environmental Science and Pharmacology, this book covers the urgent need to explore eco-friendly and sustainable approaches to healthcare, agriculture and environmental contamination management.

  • Elemene Antitumor Drugs

    Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice
    • 1st Edition
    • Tian Xie
    • English
    Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors. Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound.

  • Rapid Sensory Profiling Techniques

    Applications in New Product Development and Consumer Research
    • 2nd Edition
    • Julien Delarue + 1 more
    • English
    Rapid Sensory Profiling Techniques: Applications in New Product Development and Consumer Research, Second Edition presents the latest findings and recommendations on the proper choice and use of rapid product profiling methods. Each chapter is written by a key opinion leader on a specific method with discussions on theory, pros, cons and the application of each method that is demonstrated through a case study. This valuable resource educates and empowers those working in research and development on how to meet shorter product turnaround times at lower cost and with no compromise on quality.This book is not just needed by the scientific community, it is an essential must have in an industry challenged by a "speed to market" mantra.

  • Omics Approaches and Technologies in COVID-19

    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19. This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling andsimulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development. This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects.

  • Mitochondrial Intoxication

    • 1st Edition
    • Marcos Roberto de Oliveira
    • English
    Mitochondrial Intoxication explores the effects toxic molecules can have upon mitochondrial physiology in the human body. Each chapter is dedicated to a specific toxicant, including pollutants, food additives, illicit and pharmaceutical drugs, and heavy metals. This book considers the implications and impact these have upon mitochondria and the diseases that can result from dysfunction and impairment in the human body. Furthermore, the book provides an overview of mitochondrial physiology and assesses the advances and challenges in testing mitochondrial toxicity. Case studies exploring mitochondrial intoxication in pregnancy and in the geriatric population are also included. This is a comprehensive reference on the main toxicants impacting mitochondria in the human body, and the consequences this can have for health and disease.

  • Cardiopulmonary Bypass

    Advances in Extracorporeal Life Support
    • 1st Edition
    • Kaan Kırali + 2 more
    • English
    Cardiopulmonary Bypass: Advancements in Extracorporeal Life Support provides comprehensive coverage on the technological developments and clinical applications of extracorporeal technologies, including the underlying basic science and the latest clinical advances in the field. Written by experts around the world, this book comprises all characteristics of cardiopulmonary bypass as well as chapters regarding equipment, physiology and pathology, pediatric aspects and clinical applications. Important highlights include the latest updates regarding minimal invasive cardiopulmonary bypass (MICPB), extracorporeal circulatory and respiratory support (ECCRS) in cardiac and non-cardiac patients, ECMO support in COVID-19, and updated guidelines of extracorporeal technologies. This book is an invaluable resource to clinicians, researchers and medical students in the fields of cardiothoracic surgery, cardiac anesthesiology, intensive care, and perfusion technology.

  • Advances in Extraction and Applications of Bioactive Phytochemicals

    • 1st Edition
    • Mihir Kumar Purkait + 2 more
    • English
    Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry’s perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more. This book is a complete reference targeted at pharma researchers in academic and corporate environments and those willing to apply the most current extraction methods and health applications. Researchers in medicinal chemistry and chemical engineering will also benefit from this comprehensive resource.

  • Animal Assisted Therapy Use Application by Condition

    • 1st Edition
    • Eric Altschuler
    • English
    Animal Assisted Therapy Use Application by Condition provides the most updated and comprehensive data knowledge on animal-assisted therapy. The book synthesizes historical information, theory, clinical practice, and data from recent clinical studies on animal-assisted therapy for post-traumatic stress disorder (PTSD) and other diseases. Written by international experts drawn from the fields of medicine, clinical psychology and therapy, speech therapy, clinical research, and animal training and welfare, this book employs a hypothesis driven, data rich approach to inform readers on current research and serve as a reference for clinical practice and use of animal-assisted therapy. This is an important resource for clinicians, researchers, animal trainers and handlers and students who want to understand and utilize animal-assisted therapy in theory and practice.

  • Spinal Interneurons

    Plasticity after Spinal Cord Injury
    • 1st Edition
    • Lyandysha Viktorovna Zholudeva + 1 more
    • English
    The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons that process information within local circuits, and have an incredible ability for neuroplasticity, whether due to persistent activity, neural injury, or in response to disease. Although, by definition, their axons are restricted to the same structure as the soma (in this case the spinal cord), spinal interneurons are capable of sprouting and rewiring entire neural circuits, and contribute to some restoration of disrupted neural communication after injury to the spinal cord (i.e., “bypassing” the lesion site). Spinal Interneurons provides a focused overview of how scientists classify interneurons in general, the techniques used to identify subsets of interneurons, their roles in specific neural circuits, and the scientific evidence for their neuroplasticity. Understanding the capacity for neuroplasticity and identity of specific spinal interneurons that are optimal for recovery, may help determine cellular candidates for developing therapies. Spinal Interneurons provides neuroscientists, clinicians, and trainees a reference book exclusively concentrating on spinal interneurons, the techniques and experiments employed to identify and study these cells as part of normal and compromised neural circuits, and highlights the therapeutic potential of these cells by presenting the relevant pre-clinical and clinical work to date. People in industry will also benefit from this book, which compiles the latest in therapeutic strategies for targeting spinal interneurons, what considerations there are for the development and use of treatments, and how such treatments can not only be translated to the clinic, but how existing treatments should be appropriately reverse-translated to the bench.

  • Genomic Data Sharing

    Case Studies, Challenges, and Opportunities for Precision Medicine
    • 1st Edition
    • Jennifer B. Mccormick + 1 more
    • English
    Genomic Data Sharing: Case Studies, Challenges, and Opportunities for Precision Medicine provides a comprehensive overview of current and emerging issues in genomic data sharing. In this book, international leaders in genomic data examine these issues in-depth, offering practical case studies that highlight key successes, challenges and opportunities. Sections discuss the eMERGE Network, Undiagnosed Disease Network, Vanderbilt Biobank, Marshfield Clinic Biobank, Minnesota Authorization, Rochester Epidemiology Project, NIH sponsored biobanks, GINA, and Global Alliance for Genomics and Health (GA4GH). In addition to these perspectives from the frontlines, the book also provides succinct overviews of ethical, legal, social and IT challenges.Clinician investigators, clinicians affiliated with academic medical centers, policymakers and regulators will also gain insights that will allow them to navigate the increasingly complex ethical, social and clinical landscape of genomic data sharing.

  • State of the Art in Neural Networks and Their Applications

    Volume 2
    • 1st Edition
    • Jasjit S. Suri + 1 more
    • English
    State of the Art in Neural Networks and Their Applications, Volume Two presents the latest advances in artificial neural networks and their applications across a wide range of clinical diagnoses. The book provides over views and case studies of advances in the role of machine learning, artificial intelligence, deep learning, cognitive image processing, and suitable data analytics useful for clinical diagnosis and research applications. The application of neural network, artificial intelligence and machine learning methods in biomedical image analysis have resulted in the development of computer-aided diagnostic (CAD) systems that aim towards the automatic early detection of several severe diseases. State of the Art in Neural Networks and Their Applications is presented in two volumes. Volume One: Neural Networks in Oncology Imaging covers lung cancer, prostate cancer, and bladder cancer. Volume Two: Neural Networks in Brain Disorders and Other Diseases covers autism spectrum disorder, Alzheimer’s disease, attention deficit hyperactivity disorder, hypertension, and other diseases. Written by experienced engineers in the field, these two volumes will help engineers, computer scientists, researchers, and clinicians understand the technology and applications of artificial neural networks.

  • Agricultural Bioeconomy

    Innovation and Foresight in the Post-COVID Era
    • 1st Edition
    • Chetan Keswani + 3 more
    • English
    Agricultural Bioeconomy: Innovation and Foresight in the Post-COVID Era presents recent advancements in biotechnology, exploring the optimal utilization of technologies to provide rapid and impactful economic recovery and sustainable resources in a future that will bear the mark of COVID-19. Understanding that there is a necessary balance between risk and reward, this book provides a foundational hypothesis as well as operational direction for addressing the commercialization and regulatory issues in a bio-based economy where agricultural output is at the core. By presenting adaptable practices to successfully establish and progress agri-based global bioeconomies, the book features a new paradigm focused on technological foresight and response to future risks and disasters. Key considerations include assessing and managing the urban bioeconomy, climate change mitigation, biofuels and bioenergy, GMOs, and employment generation. This book provides the solid next step toward future-proofing global economies using a combination of agricultural technologies and economic goals. Professionals and advanced students focused on the production of renewable biological resources and their conversion into value-added products including food, feed, bio-based products, and bioenergy will find this book useful.

  • Neurocircuitry of Addiction

    • 1st Edition
    • Nicholas W. Gilpin
    • English
    People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction.

  • Neglected and Underutilized Crops

    Future Smart Food
    • 1st Edition
    • Muhammad Farooq + 1 more
    • English
    Neglected and Underutilized Crops: Future Smart Food explores future food crops with climate resilience potential. Sections cover their botany, nutritional significance, global distribution, production technology, and tolerance to biotic and abiotic stresses of neglected and underutilized crops. By simply changing species in a crop rotation system, the cycle of some pests and diseases is disrupted and probabilities of infestations are reduced. Finally, the book provides case studies that highlight where the adaptation of crops to local environments, especially with regard to climate change, have been successful.These crops can help make agricultural production systems more resilient to climate change. Although a few books on neglected and underutilized crops are available, this comprehensive book covers the full scope of crop husbandry, nutritional significance and global distribution.

  • Data Science for Genomics

    • 1st Edition
    • Amit Kumar Tyagi + 1 more
    • English
    Data Science for Genomics presents the foundational concepts of data science as they pertain to genomics, encompassing the process of inspecting, cleaning, transforming, and modeling data with the goal of discovering useful information, suggesting conclusions and supporting decision-making. Sections cover Data Science, Machine Learning, Deep Learning, data analysis, and visualization techniques. The authors then present the fundamentals of Genomics, Genetics, Transcriptomes and Proteomes as basic concepts of molecular biology, along with DNA and key features of the human genome, as well as the genomes of eukaryotes and prokaryotes. Techniques that are more specifically used for studying genomes are then described in the order in which they are used in a genome project, including methods for constructing genetic and physical maps. DNA sequencing methodology and the strategies used to assemble a contiguous genome sequence and methods for identifying genes in a genome sequence and determining the functions of those genes in the cell. Readers will learn how the information contained in the genome is released and made available to the cell, as well as methods centered on cloning and PCR.

  • The Veterinarian’s Guide to Animal Welfare

    • 1st Edition
    • Bonnie V. Beaver + 1 more
    • English
    The Veterinarian’s Guide to Animal Welfare provides an overview of various aspects of animal welfare that are particularly relative to the veterinary profession. The book explores various ways of viewing and assessing welfare, as well as the numerous factors that influence perceptions. Emphasis is placed on contemporary issues across, and within, major species groups. The book's authors are internationally known experts in the veterinary aspects of animal welfare and have written numerous articles on animal welfare, behavior, euthanasia and the human-animal bond. This book is written for the veterinary profession and was designed to be used as a textbook for animal welfare courses at colleges and schools of veterinary medicine. It complements the Model Curriculum for the Study of Animal Welfare (AVMA 2015) and its attendant course syllabus. This is an important resource for graduate veterinarians seeking to improve their understanding of the numerous aspects of animal welfare.

  • Frontiers in Aquaculture Biotechnology

    • 1st Edition
    • W.S. Lakra + 2 more
    • English
    Frontiers in Aquaculture Biotechnology presents a broad-spectrum of topics, covering different key aspects of aquaculture. With the rising importance of aquaculture research, evidence-based information is integral in advancing this field. This book provides a solid resource of information on DNA barcoding for fish species authentication and seafood labelling and cell culture, including stem cell culture, in vitro research using fish cell lines such as in vitro fish meat, reproductive biotechnology, including surrogate technology, gene editing and genetically modified aquaculture species, biofloc technology, and omic technologies such as proteomics, artificial intelligence and biobanking. This book will be a valuable resource to students, researchers a nd entrepreneurs interested in a better understanding of this emerging field of aquaculture.

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