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Books in Life sciences

  • Gold Nanoparticle Therapeutics in Alzheimer's Disease

    • 1st Edition
    • Arun Kumar Singh + 2 more
    • English
    Gold Nanoparticle Therapeutics in Alzheimer's Disease: Revolutionizing Diagnosis and Treatment is an essential resource that delves into the groundbreaking use of nanotechnology in the fight against one of the most challenging neurodegenerative disorders. This volume offers an in-depth exploration of how gold nanoparticles can be used to enhance the diagnosis, treatment, and overall understanding of Alzheimer's disease. By examining the molecular mechanisms that enable nanoparticles to cross the blood-brain barrier, the book highlights their role in inhibiting amyloid fibrils and their potential as precise diagnostic tools. Covering a wide range of topics, this comprehensive guide serves as an invaluable reference for researchers, clinicians, and industry professionals at the forefront of Alzheimer's research and nanomedicine.

  • Biomarkers in Neurological Disorders and Treatment

    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Decoding the Brain: Biomarkers in Neurological Disorders and Treatment seeks to provide a comprehensive exploration of the latest advances in neurological biomarkers, detailing their discovery, validation, and application in clinical practice. By offering insights into the biological underpinnings of various neurological disorders, this book aims to bridge the gap between cutting-edge biomarker research and its practical implementation in patient care.

  • Fundamentals of Translational Tissue Engineering

    • 1st Edition
    • Yogesh Kumar Verma + 3 more
    • English
    Fundamentals of Translational Tissue Engineering explores the practical dimensions of tissue engineering (TE), outlining the intricate path of development of tissue engineered products. The book navigates the reader through the fundamental aspects and challenges in TE, equipping the reader with insights crucial to comprehending the journey a tissue engineered product traverses on its way to clinical translation. The first section, Material Sciences, provides the reader with a general overview covering the basics of scaffolds, biomaterials and techniques, while the larger, second section, Biological and Clinical Aspects, discussing the biological perspectives relating to tissue engineering.This is a multi-disciplinary work that will be ideal for audiences of varying levels of expertise, from the novice exploring fundamental concepts or the seasoned professionals seeking comprehensive information, readers of all backgrounds will be able to access and benefit from this tailored approach.

  • Modern fMRI

    Practical Lessons and Insights
    • 1st Edition
    • Andrew Jahn
    • English
    The field of neuroimaging with fMRI is developing at a rapid pace, with a seemingly endless number of software packages, statistical methods, and different ways to organize and analyze neuroimaging data. Among such a wide variety of options, and with so many seemingly conflicting pieces of advice on the “correct” way of analysing neuroimaging data, knowing what decisions to make is a difficult task.Modern fMRI: Practical Lessons and Insights provide an up-to-date, holistic overview of the field of functional magnetic resonance imaging (fMRI), familiarizing the reader with the latest trends in neuroimaging such as standardized data organization and preprocessing, advances in functional connectivity and machine learning, and current guidelines in data and code sharing. This includes advice about best practices in preprocessing, statistical modeling, QA checks, and some of the latest tools and concepts to be familiar with, including fMRIPrep, OpenNeuro.org, Open Science practices, and Jupyter notebooks.

  • CDK4/6 inhibitors in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 3 more
    • English
    CDK4/6 inhibitors in Breast Cancer Therapy examines the pivotal role of CDK4/6 inhibition in treating hormone receptor-positive (HR+)/HER2-negative advanced breast cancer. The book highlights FDA-approved applications of these inhibitors alongside endocrine therapy and explores ongoing research into their potential as neoadjuvant treatments. It provides insights into the drug discovery and development of CDK4/6 inhibitors, covering their molecular mechanisms, pharmacology, and clinical applications. Chapters address their use in mono and adjuvant therapies, as well as challenges in targeting, while also discussing market potential and post-marketing safety issues.This book is a valuable resource for researchers and academics, enhancing understanding of CDK4/6 inhibitors' chemistry and therapeutic implications. By presenting detailed information on clinical trials and market formulations, it equips the audience with essential knowledge to navigate the complexities of targeted breast cancer therapies and contributes to advancing research in this critical area.

  • Aggressive Behavior of People with Autism and other Intellectual and Developmental Disability

    • 1st Edition
    • Lauren Charlot + 1 more
    • English
    While people with autism and other intellectual and developmental disabilities receive extensive services for their behavioral health needs, many continue to struggle and lack a positive quality of life. The primary reason for referral for professional mental health care is most often the occurrence of aggression and other externalizing behaviors. Aggressive Behavior of People with Autism and other Intellectual and Developmental Disability explores the primary factors influencing the occurrence of aggression in this population are reviewed, and offers practical suggestions for improving outcomes. Topics covered include understanding effects of neurodevelopmental disorders, multiple factors frequently impacting risk for aggression, common medical and neurological influences, and the effects of trauma. This book will also introduce a new model for integrating multiple influences into a contextual functional behavior assessment.

  • Technology-Assisted Physical Gait Rehabilitation

    How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy
    • 1st Edition
    • Tomislav Baček + 3 more
    • English
    Technology-Assisted Physical Gait Rehabilitation: How Robotics, Data Science, and Neuroscience are Changing Modern Physical Therapy explores computational modeling techniques, robotic assistance, data science, and other technological tools and how they can be jointly used in driving and guiding physical gait therapy in impairments such as stroke, traumatic brain injury, and incomplete spinal cord injury. This book gathers experts in robotics, human biomechanics, physical therapy, neuroscience, engineering, and medicine, presenting their ongoing work and discusses their views of the future direction of technology-assisted gait therapy, showcasing the latest advancements in the interdisciplinary and multidisciplinary field of technology-assisted gait therapy and strives to outline the developments in the coming years that are needed/likely to make the next big breakthrough in the field.

  • Microscopy in the Life Sciences from 1650 to the Present

    • 1st Edition
    • Joel B. Sheffield
    • English
    Microscopy in the Life Sciences from 1650 to the Present explores the transformation of the microscope and its applications and techniques over the course of history, illustrating how progress in optics and microscope design has informed our growing knowledge of cellular life. Beginning with early observations of cellular structure, the book tracks the movement towards understanding of cell biology and pathology, considering the changing landscape of microscopy, lens development, and limitations and challenges tackled. Users will also find content on recent advances, including fluorescence studies and the use of computational procedures to assemble images of individual molecules.This book traces the evolution of understanding that scientists have had regarding cellular life and how comprehension of this has been supported by the development of the microscope. It considers a range of experts central to its progression over the years, including Schleiden, Schwann, Abbe, Schott and Zeiss, and is a useful reference for researchers working with microscopy techniques across the biological sciences.

  • Boorman's Pathology of the Rat

    Reference and Atlas
    • 3rd Edition
    • Andrew W. Suttie + 6 more
    • English
    Boorman’s Pathology of the Rat: Reference and Atlas, Third Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry.In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations.The new edition includes topics not covered previously with contributors who at the forefront of each specific topic.  This book is the most comprehensive publication on rat pathology, now revised to include all rat strains and with an added emphasis on the Sprague-Dawley and Wister. It is an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to promulgation of meaningful regulations.

  • Marination

    A Novel Technology to Improve the Quality and Safety of Foods
    • 1st Edition
    • Ioannis Savvaidis + 1 more
    • English
    Marination: A Novel Technology to Improve the Quality and Safety of Foods presents the latest developments in marination as a method of intervention in providing an improvement in food quality and assuring the safety of perishable foods.Composed of 12 chapters, the title covers marination types and its applicability in various food types (fish/seafood, meats, plant-based fresh produce, dairy-based products). Besides presenting the existing technologies to improve the quality of foods and to extend its shelf-life. The book also discusses marination as both a preservation technique and a technology to produce novel foods to consumers. Marination and mathematical models combined with spectroscopic techniques is also presented in the book. Edited by a team of experts in the field, this book is a unique resource for researchers, scientists and industry personnel interested in natural techniques for preserving food and preventing the growth of food pathogens.

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