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Elsevier

Books in Life sciences

  • Novel Uses of Mushrooms in Foods and Nutraceuticals

    • 1st Edition
    • Yugal Kishore Mohanta + 3 more
    • English
    In an era where sustainable agriculture and health-promoting foods are more vital than ever, Novel Uses of Mushrooms in Foods and Nutraceuticals explores the diverse potential of mushrooms as a cornerstone of future food systems. Covering a broad spectrum of innovations, including advanced cultivation techniques, molecular breeding, and nanotechnology aimed at maximizing mushroom productivity and product diversity, this book analyzes the classification, taxonomy, and biological properties of edible and medicinal mushrooms, providing essential knowledge for researchers and industry professionals seeking to develop high-value functional foods and nutraceuticals. Highlighting recent breakthroughs, Novel Uses of Mushrooms in Foods and Nutraceuticals examines the application of mushroom-derived proteins, bioactive compounds, and natural pigments in health, cosmetics, and industrial sectors. It explores mushroom-derived pre- and probiotics and their impact on the gut microbiota and emphasizes the role of mushrooms in sustainable practices such as bioremediation, circular economy, and biodegradable packaging. With insights into policy, global trade, and future trends, this volume equips readers to drive innovation and sustainable growth in the mushroom industry.

  • Spaceflight Ophthalmology and Medicine

    A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers
    • 1st Edition
    • Ryung Lee + 4 more
    • English
    Spaceflight Ophthalmology and Medicine: A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers provides a comprehensive exploration of ocular health issues faced by astronauts during space missions. The book brings together contributions from leading experts in various fields, addressing the multifaceted risk factors associated with spaceflight and their implications for vision and overall health. Sections examine risk factors for ophthalmic diseases, including the effects of microgravity, space radiation, and oxidative stress, and explore innovative approaches in spaceflight ophthalmology, such as advanced diagnostic techniques and potential treatments for ocular conditions specific to the space environment. This book serves as an essential resource for researchers, clinicians, and space medicine professionals. By offering insights into the latest research and practical applications, it enhances understanding of ocular health in space and promotes the development of effective strategies to ensure astronaut safety and mission success.

  • AI and Global Health

    Unlocking Transformative Potential
    • 1st Edition
    • Adil Haider
    • English
    AI and Global Health: Unlocking Transformative Potential provides a roadmap for practitioners to apply and leverage artificial intelligence to strengthen health systems using the World Health Organization's health systems approach. The book's combination of case studies and secondary research inspires the possibility of what can happen using AI in healthcare, ensuring the use of robust, scientific evidence to draw conclusions. Additionally, readers will learn from others in settings where AI has been a tool for change, providing healthcare practitioners and policymakers with what they need to think through how it can be applied in resource limited settings.The book provides a strong call to action for policymakers and healthcare leaders of governments, international organizations, and healthcare institutions to take the lead in AI implementation as a key lever for advancing global health goals through a systems approach. As AI is a rapidly evolving field with significant investment made in this industry in recent years from government and the private sector, this book articulates how this growth can be harnessed for countries that need a different approach to addressing global health problems.

  • Smart Approaches for Cancer Diagnosis, Therapy, and its Associated Challenges

    • 1st Edition
    • Paul A. Millner + 2 more
    • English
    Smart and Translational Approaches in Cancer Diagnosis and Therapy: Innovations and Challenges presents a comprehensive exploration of cutting-edge technologies transforming cancer care. This edited volume bridges foundational science with clinical relevance, offering insights into theranostics, nanomedicine, and molecular therapeutics. The book delves into advanced diagnostic tools such as biosensors and theranostic nanoparticles, and therapeutic innovations including peptide-drug conjugates, epigenetic modulation, and nucleic acid-based treatments. It addresses key challenges in glioblastoma, pediatric brain tumors, and drug-resistant cancers, while highlighting translational strategies that integrate diagnostics and therapy. Academics benefit from a multidisciplinary reference that supports research, fosters innovation, and enhances understanding of emerging cancer therapies. It equips researchers with the latest developments to advance precision medicine and improve patient outcomes.

  • Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine

    • 1st Edition
    • Anthony Chang + 1 more
    • English
    Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. This book vastly improves the speed of adoption of AI in pediatric and neonatal healthcare by providing a framework of AI deployment in children and healthcare. In addition to a large section on the principles and theories of artificial intelligence as well as its application in a number of pediatric subspecialties, the book will have about 50 commentaries that all have the same structure The book is presented in a systematic manner for all clinicians to understand the in-depth thinking of the leaders in the pediatric AI domain from an international perspective. Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. It also offers a framework for success in planning, deployment, implementation, and evaluation of AI models in healthcare. In addition, current state of the art of pediatric subspecialties will be presented with future directions to guide the pediatric and neonatal clinicians. Finally, a colorful collection of commentaries by leaders of AI use in children’s health is inserted throughout the book.

  • Fluid Dynamics of Viral Transmission

    • 1st Edition
    • Mehrzad Shams + 1 more
    • English
    Fluid Dynamics of Viral Transmission is an essential exploration into the transmission dynamics of COVID-19, focusing specifically on the airborne spread of respiratory aerosols carrying infectious viruses. In light of the recent global pandemic, it offers crucial insights into the complex interaction between fluid dynamics and viral transmission and provides practical solutions for minimizing risks in indoor environments. The book delves into CFD simulations, optimizing ventilation systems, air filtration strategies, and spatial layout modifications. It evaluates mitigation measures such as mask-wearing, physical distancing, and occupancy limits, aiming to equip readers with the knowledge to create safer indoor spaces. This book is ideal for public health officials, policymakers, healthcare professionals, engineers, researchers, and academics in fluid mechanics, computational fluid dynamics, epidemiology, and virology.

  • Basic Neurochemistry

    Principles of Molecular, Cellular, and Medical Neurobiology
    • 9th Edition
    • Scott Brady + 1 more
    • English
    Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions).This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

  • Quick Guide to Hemostasis and Transfusion Medicine

    • 1st Edition
    • George A. Fritsma + 3 more
    • English
    Quick Guide to Hemostasis and Transfusion Medicine is a patient reference that recommends indication-based laboratory test selection and interpretation to diagnose and treat hemorrhagic and thrombotic disorders using blood components, biologics, and synthetic therapeutics. The book introduces hemostasis and transfusion medicine for students, residents, and fellows, supplementing standard texts. It uses headings, bulletpoints, telegraphic syntax, tables, figures, and speedy lookup features and is an essential quick reference for health care providers who order, perform, and interpret hemostasis and immunohematology assays and administer hemostasis therapy.

  • Human-AI-Cognitive Intelligence Software, System, and Services for Quality Assurance

    Theories and Methods with Systems Thinking for Behaviour Change in the Medical Decision-Making Pathway
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Habit-based Behavior Change Medical Information Support System and Artificial Intelligence: Theories, Methods, and Data Analytics Approach provides a guideline to design and implement Habit-based Behavior Change Support Systems (HBCSS) which can change patient’s unhealthy habits to prevent the development of diseases. It presents theories, methods, management, and data analytics approach required to design, implement, and prescribe the use of HBCSS for several diseases’ management.It discusses topics such as theories of behavior change, ontologies and knowledge management, data mining, privacy and security, descriptive and prescription analytics. In addition, it discusses how to measure habit-change, future directions of the field, and case studies based on real-world examples.It is a valuable resource for clinicians, researchers, students, and member of the biomedical and medical fields who want to learn more about the use of medical systems to improve patients’ health.

  • Human Reproduction

    From basics to Biotechnology
    • 1st Edition
    • Marc yeste
    • English
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

  • Biology of Aging Accelerators

    Fundamentals, Hallmarks and Therapeutic Interventions
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    Biology of Aging Accelerators: Fundamentals, Hallmarks and Therapeutic Interventions explores how biological, genetic, and environmental factors affect cellular and systemic homeostasis and lead to accelerated aging. The book begins with a historical perspectives, highlighting the growth in immune system deterioration, chronic illness, and social issues. It then examines the hallmarks of aging, including primary, antagonistic, and integrative characteristics that may or may not be contributors. Subsequent chapters explore basic concepts and key accelerators in human biology, the role of biological clocks, and mechanisms of aging accelerators such as cellular senescence, DNA damage, and mitochondrial dysfunction.The book also addresses how different organs age at different rates and the brain's role as the body's aging integrator and provides actionable insights into innovative therapies aimed at reducing or stopping the signs and symptoms of aging, including developments in medications, lifestyle adjustments, regenerative medicine, and cutting-edge technologies like stem cell therapy and CRISPR. By integrating scientific research and practical insights, this book offers a realistic perspective on anti-aging research and stimulates novel ideas for improving quality of life.

  • Advances in Agronomy

    • 1st Edition
    • Volume 201
    • English
    Advances in Agronomy, Volume 201, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • GANs in Medical Diagnostics and Classification

    • 1st Edition
    • Abhishek Kumar + 1 more
    • English
    GANs in Medical Diagnostics and Classification explores the role of Generative Adversarial Networks (GANs) in addressing underdiagnosed and overlooked health challenges. The book bridges cutting-edge AI research with real-world medical applications, presenting interdisciplinary insights into how GANs enhance diagnostics, treatment precision, and disease surveillance across domains such as antimicrobial resistance, rare genetic disorders, and environmental health risks. It also examines ethical, policy, and accessibility dimensions of AI in healthcare. By combining technical depth with practical case studies, this volume equips medical researchers, AI engineers, and healthcare professionals with actionable knowledge to tackle silent epidemics using GAN-based tools.

  • Geographic Atrophy in Age-related Macular Degeneration

    • 1st Edition
    • Jay Chhablani + 1 more
    • English
    Geographic Atrophy in Age-related Macular Degeneration provides a comprehensive resource on this flourishing discipline, focusing on accurate diagnosis, imaging features, clinical trials, differential diagnoses, and both established and emerging treatment options. The book details diagnostic processes using techniques such as visual acuity tests, dilated eye exams, fundus photography, optical coherence tomography (OCT), and fluorescein angiography, emphasizing the importance of early detection. It also differentiates geographic atrophy from other retinal conditions with similar symptoms, such as dystrophies, equipping practitioners with the knowledge for accurate diagnosis.Additional... it explores traditional management approaches like antioxidant supplements, lifestyle changes, and low vision aids, alongside novel treatments such as complement inhibitors, cell-based therapies, and gene therapy, to inform clinicians about the latest advancements and research in patient care. With the recent FDA approval for GA treatment, there has been significant interest in the retina community. This rapidly growing field necessitates a new book on geographic atrophy in age-related macular degeneration to address gaps in existing literature and provide up-to-date, comprehensive information.

  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1st Edition
    • Gary Tse + 3 more
    • English
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.

  • Animal Cognition

    Fundamentals, Models, and Therapeutic Advances
    • 1st Edition
    • Shampa Ghosh + 3 more
    • English
    Animal Cognition: Fundamentals, Models, and Therapeutic Advances provides a comprehensive overview of cognitive processes in various animal species, spanning fundamental concepts, species-specific studies, and therapeutic applications. Sections cover the foundation of animal cognition, including definitions, key concepts, and an overview of cognitive abilities, such as memory, problem-solving, and learning, delve deeper into the cognitive processes in mammals, birds, and marine animals, and more, and review the latest technological advancements in studying cognition, such as neuroimaging, machine learning, and virtual reality. With a multidisciplinary approach, this volume highlights current research while identifying gaps for future exploration, and will be of interest to researchers involved in animal cognition and behavioral neuroscience.

  • Molecular Mechanisms of Cancer Resistance

    Emerging Technologies and Therapeutic Strategies
    • 1st Edition
    • Ahmet Acar
    • English
    Molecular Mechanisms of Cancer Resistance: Emerging Technologies and Therapeutic Strategies explores innovative tools and strategies designed to address the critical issue of drug resistance in cancer treatment. This comprehensive volume is tailored for researchers, clinicians, and students, offering insights into the latest advancements and methodologies in the field. The book covers essential topics such as molecular mechanisms of drug resistance, the tumor microenvironment, and emerging technologies like single-cell analysis and computational modeling. Each chapter features contributions from leading experts, providing a multi-dimensional perspective on both foundational concepts and cutting-edge research.By engaging with this book, the academic audience gains access to groundbreaking research and therapeutic strategies that enhance understanding and practice. The knowledge acquired will inspire collaboration and innovation, ultimately contributing to more effective and personalized cancer treatment approaches.

  • The Brain Histaminergic System in Health and Disease

    • 1st Edition
    • Zhong Chen + 2 more
    • English
    Histamines in Neurology and Psychiatry summarizes histamines and their impact on neuroinflammation and brain development in key neural circuits. This book presents the latest research on the physiological regulation of a neuroendocrine responses and releases, broadly discussing histamine receptor modulators and histamine effects in neurology and psychiatry, and also including clinical applications that will be of interest to practitioners.

  • Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine

    • 1st Edition
    • Cheng Xue + 3 more
    • English
    Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine provides a comprehensive exploration into the molecular signatures and clinical implications of urine biomarkers, providing invaluable insights for clinicians, researchers, and healthcare professionals. From historical perspectives to cutting-edge technologies, this reference presents an updated understanding of urine biomarkers' role across diverse bodily systems. With sections devoted to fundamental concepts, molecular signatures, and clinical applications, readers gain a deep understanding of urine biomarkers' significance in disease diagnosis and personalized medicine.Each chapter explores specific body systems, including renal, urological, cardiovascular, and respiratory, uncovering the diagnostic potential of urine biomarkers in various conditions like cancer, cardiovascular diseases, and neurological disorders. Highlighted are the latest advances in technology, challenges, and future directions, keeping readers abreast of the rapidly evolving landscape of urine biomarker research. Real-world case studies illustrate practical applications, enhancing comprehension and facilitating knowledge transfer to clinical practice.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 136
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advanced and Sustainable Biotechnologies from Fungi

    Functional Foods and Nutraceutical Production
    • 1st Edition
    • Pragya Tiwari + 1 more
    • English
    Advanced and Sustainable Biotechnologies from Fungi: Functional Foods and Nutraceutical Production provides insights into existing and emerging fungal biotechnologies, along with advances in high-throughput technologies to enhance the sustainable production of bio-based functional foods and nutraceuticals of fungal origin. Focusing on the emerging, global concern of hunger and malnutrition, this book explains how fungi-based biotechnologies offer prospective solutions to address the global food shortage using functional foods and nutraceuticals. Chapters cover the major portion of novel sources and various biotechnological approaches used for the production of functional foods and nutraceuticals from microorganisms and mushrooms and their applications in the industry. In addition, the book includes the existing and emerging biotechnological trends and approaches in enhanced production of Functional food and Nutraceuticals of fungal origin, such as Omics-guided advances, computational strategies, and biotechnological tools. 3D printed fungal food products, and social, ethical, and regulatory aspects of functional food and nutraceutical products are also discussed. Authored by a team of experts in the field of fungi biotechnology, this book serves as a reference material for food microbiologists, food scientists, and pharmaceutical professionals for the development of new functional foods and nutraceuticals.

  • AI-Driven Plant Science

    Advancing Crop Performance Through Omics Integration and Physiology
    • 1st Edition
    • Osamah Shihab Albahrey + 1 more
    • English
    AI-Driven Plant Science: Advancing Crop Performance Through Omics Integration and Physiology offers cutting-edge insights into the rapidly evolving fields of precision agriculture, Artificial Intelligence, plant biotechnology and genetic engineering, and bioinformatics. With a strong focus on applications in smart agriculture, crop improvement, and environmental adaptation, it bridges the gap between advanced research and practical implementation. The rapid advancements in AI and biotechnology have created both opportunities and complexities for the agricultural sector. This book fills a critical gap in the existing literature by providing a multidisciplinary resource that integrates AI, biotechnology, and agricultural science. While there are numerous resources on plant biology and AI individually, few works explore their synergistic potential in depth. This book offers actionable insights into how AI can revolutionize crop physiology, stress tolerance, and plant-based research. It also highlights the challenges and ethical considerations of integrating AI into agricultural practices, ensuring a balanced and forward-thinking perspective. AI-Driven Plant Science: Advancing Crop Performance Through Omics Integration and Physiology provides a definitive guide for researchers, industry professionals, and students seeking to understand and apply AI in plant science and crop production.

  • Biomechanics of the Heart

    From Model to Patient
    • 1st Edition
    • Peter Bovendeerd + 3 more
    • English
    Biomechanics of the Heart: From Model to Patient provides readers with a comprehensive overview of the modeling and assessment of the heart’s biomechanics. The book addresses topics such as the physiology of normal and diseased hearts, cardiovascular imaging, modeling of myocardial tissue in the passive and active states, as well as state-of-the-art approaches for patient specific modeling of the heart’s mechanical function. This is all augmented by case studies and examples of exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases. Readers are introduced to modeling of the heart’s anatomical and muscular structure, a review of imaging techniques to analyze the geometry, content and dynamics of the heart, as well as an in-depth look at the biomechanical properties of normal and diseased hearts. Finally, chapters cover modeling cardiac passive and contractile mechanics, biomechanical finite element simulations of the heart, patient-specific modeling of the heart and circulatory system, as well as the exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 72
    • English
    Advances in Insect Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Genetic Advances in Inborn Errors of Immunity

    • 1st Edition
    • Volume 117
    • English
    Genetic advances in inborn errors of immunity, published as Volume 117 of the serial Advances in Genetics, provides a comprehensive and up‑to‑date overview of the rapidly evolving genetic landscape underlying inborn errors of immunity (IEI). Bringing together authoritative contributions from leading experts, this volume examines how advances in genomics, molecular diagnostics, and functional immunology have transformed the understanding, classification, and clinical management of primary immunodeficiency disorders. The chapters span severe monogenic conditions to complex, polygenic phenotypes, highlighting both mechanistic insights and translational implications. Collectively, the volume serves as an essential reference for researchers and clinicians seeking to understand how genetic discoveries are reshaping immunology and precision medicine.

  • Biomarkers in Neurological Disorders and Treatment

    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Decoding the Brain: Biomarkers in Neurological Disorders and Treatment provides a comprehensive exploration of the latest advances in neurological biomarkers, detailing their discovery, validation, and application in clinical practice. By offering insights into the biological underpinnings of various neurological disorders, this book aims to bridge the gap between cutting-edge biomarker research and its practical implementation in patient care.

  • A Guide to Brief Clinical Interventions in Inpatient and Abbreviated Settings

    • 1st Edition
    • Elaheh Ashtari + 3 more
    • English
    There are many resources available for evidence-based psychotherapies in outpatient and other long-term settings, but limited resources are available for inpatient and other brief settings. A Guide to Brief Clinical Interventions in Inpatient and Abbreviated Settings offers a problem-focused psychotherapeutic approach applicable to brief and long-term care settings. The text will this text will include explicit cultural considerations when applying brief treatment, and promote cultural responsiveness across treatment providers and care settings. This multimodal, evidence-informed handbook is intended for behavioral health and mental health practitioners alike who desire to deliver high quality interventions in time limited settings, such as acute and subacute inpatient units.

  • Biosimilars in Cancer

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Biosimilars in Cancer is a comprehensive resource on the role of biosimilars in treating various cancer types. The book offers a succinct yet thorough overview of current trends in oncology, covering 21 different cancers from liver to breast cancer. Chapters provide detailed insights into trends, fundamental facts, and practical and clinical data, making it an invaluable tool for academics and practitioners. The book empowers researchers and clinicians to enhance understanding and improve patient outcomes through the effective use of biosimilars in oncology. Targeted primarily at pharmaceutical researchers, biomedical scientists, and clinicians, it supports the growing oncology biosimilars market.In addition, the book provides critical insights for those involved in cancer diagnostics and clinical trials, helping them stay ahead in this rapidly progressing field.

  • Drug Discovery

    Traditional Approaches and Advanced Strategies
    • 1st Edition
    • Renren Bai
    • English
    Drug Discovery: Traditional Approaches and Advanced Strategies is a foundational monograph that connects established methodologies, cutting-edge technologies, and the transformative impact of AI and other emerging tools in the drug discovery landscape. Sections provide an overview of drug discovery and development, introducing current trends and the evolving landscape of the field, explore traditional approaches alongside advanced strategies, covering topics such as drug target discovery, lead optimization, and the revolutionary role of artificial intelligence in drug discovery, and investigate promising emerging technologies, including targeted protein degradation and innovative design strategies. Equipping readers with insights into the future of drug development, this is a vital resource for academic and industrial researchers, students, and professionals seeking to stay at the forefront of drug discovery. By integrating traditional methodologies with the latest advancements, this book not only enhances understanding but also inspires innovation. With practical case studies and real-world applications, it empowers researchers to effectively implement new technologies, ultimately improving the efficiency and success rates of their R&D endeavors.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 2nd Edition
    • Joao L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics, Second Edition provides the latest research advances, including interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the novel optogenetic techniques revolutionizing depression research. This new edition aids advanced students and researchers in their understanding of MDD, presenting chapters that explore groundbreaking topics such as the neurobiology of treatment-resistant depression, the mechanisms that make ketamine a better antidepressant, and the link between depression and Alzheimer's disease. Additionally, it covers the neurobiology of suicide in depression, the impact of psychedelics as therapy, and the unique aspects of bipolar depression.The book also examines computational models in depression, the neurobiology of psychotherapy, and the putative mechanisms of action for vagus nerve stimulation as a therapeutic approach. These additions help provide a broader and more comprehensive understanding of depression and its treatment.

  • Integrating Artificial Intelligence with Virtual Screening

    A New Era in Drug Discovery
    • 1st Edition
    • Vivek Asati + 1 more
    • English
    Integrating Artificial Intelligence with Virtual Screening: A New Era in Drug Discovery addresses the evolving landscape of drug discovery by combining traditional virtual screening with cutting-edge artificial intelligence technologies. This volume offers an interdisciplinary guide to AI-driven ligand and structure-based screening methods, including machine learning, deep learning, and generative models, thus enabling faster and more accurate identification of drug candidates. It covers mathematical models, computational workflows, and optimization strategies such as Pareto-based and physics-based approaches.Sections also discuss challenges in navigating ultra-large chemical libraries and present practical case studies that demonstrate real-world applications. Edited by leading researchers, the book provides authoritative insights suited for graduate students, researchers, and industry professionals. Users will be empowered by the latest tools and knowledge to innovate drug discovery pipelines and support the development of precision medicines and foster advancements in pharmaceutical sciences.

  • Neurological and Neuropsychiatric Disorders

    Substance Use and Addictive Behaviors
    • 1st Edition
    • Alexander Baldacchino + 1 more
    • English
    Khazaal and Baldacchino_Neurolog... and Neuropsychiatric Disorders: Substance Use and Addictive Behaviors is an essential resource that delves into the intricate relationship between substance use, addictive behaviors, and their profound impact on neurological and neuropsychiatric health. The book presents a comprehensive examination of the various disorders and conditions that arise from, or are exacerbated by, substance use and addictive behaviors, offering a multidisciplinary approach to understanding these complex interactions. This volume provides a detailed and updated exploration of the neurological and neuropsychiatric consequences of substance use and addictive behaviors.By compiling the latest research and clinical insights, this volume aims to fill a critical gap in the existing literature, which often treats substance use disorders and neurological impacts as separate entities. This integrated approach is crucial for both researchers and clinicians who need a thorough understanding of the co-morbidities associated with addiction. This book solves the problem of fragmented knowledge by offering a unified perspective that is crucial for developing effective treatment strategies and understanding the full spectrum of addiction-related disorders.

  • Microbiome and Tumorigenesis in Different Cancers

    • 1st Edition
    • Sanjana Mehrotra + 1 more
    • English
    Microbiome and Tumorigenesis in Different Cancers delves into the intricate relationship between the human microbiome and various health conditions, with a particular focus on cancer. It is divided into five parts, each addressing a critical aspect of microbiome research and its implications for health and disease. In 4 parts, the book provides a foundational understanding of the human microbiome, examines the dual role of the microbiome in cancer development, discusses the role of dysbiosis in gastrointestinal, skin, oral, lung, genitourinary, and hematological malignancies, and gives an overview of the methodologies used to study the microbiome.The final part explores the emerging field of pharmacomicrobiomics... focusing on the interaction between the microbiome and cancer therapies. This book serves as a valuable resource for researchers, clinicians, and students interested in understanding the complex interplay between the microbiome and cancer, offering insights into potential therapeutic strategies and future directions in microbiome research.

  • An Essential Guide to Radiation Dosimetry for Medical Applications

    Principles, Technologies, and Clinical Applications
    • 1st Edition
    • Jayachandran Venkatesan + 1 more
    • English
    An Essential Guide to Radiation Dosimetry for Medical Applications: Principles, Technologies, and Clinical Applications provides a comprehensive overview of the fundamental concepts, advanced methodologies, and emerging technologies in radiation dosimetry. This book serves as an essential resource for researchers, clinicians, and students involved in cancer research, bioinformatics, medical physics, radiology, and radiation therapy, offering in-depth insights into both theoretical principles and practical applications. The content covers core topics such as radiation interactions, dosimetry materials, and simulation techniques, alongside clinical and diagnostic applications.In addition, it also explores innovative approaches like artificial intelligence, nanodosimetry, and quality assurance, ensuring readers stay current with technological advancements. This book benefits the academic audience by enhancing their knowledge of dosimetry science and fostering the development of safer, more effective radiation practices. It supports education, research, and clinical decision-making, ultimately advancing the field of radiation physics and improving patient outcomes.

  • Advances in Medical Simulation

    Techniques, Applications and Innovations
    • 1st Edition
    • Noor Zaman Jhanjhi + 2 more
    • English
    Advances in Medical Simulation: Techniques, Applications, and Innovations explores cutting-edge developments in medical simulation, focusing on its transformative role in medical education, training, and patient care. The book examines various simulation techniques, including virtual and augmented reality, high-fidelity mannequins, and task trainers, showcasing their applications in surgical training, clinical diagnostics, and emergency response. Sections provide an in-depth discussion of the challenges and future directions in medical simulation, highlighting innovations such as robotics and artificial intelligence. By addressing gaps in existing literature, this book offers a comprehensive understanding of how advanced simulation techniques can enhance healthcare professionals' skills and competencies.For the academic audience, this book serves as a vital resource that bridges research and practical applications in clinical settings. It identifies trends and opportunities for future innovation, ultimately aiming to reduce medical errors and improve patient safety through effective simulation-based practices.

  • Nanoengineered Drug Delivery Systems for Oral and Head & Neck Cancer

    Targeting the Tumor Microenvironment
    • 1st Edition
    • Raghvendra Ashok Bohara
    • English
    Nanoengineered Drug Delivery Systems for Oral and Head & Neck Cancer: Targeting the Tumor Microenvironment explores innovative nanotechnologies designed to improve treatment outcomes for oral and head and neck cancers. The book integrates molecular design, nanotechnology, and clinical translation, emphasizing targeted drug delivery strategies that modulate the tumor microenvironment. It provides comprehensive coverage of tumor biology, early detection, molecular targets, and advanced delivery systems like liposomes and stimuli-responsive nanocarriers.The content also highlights emerging areas such as immune engineering, AI-assisted design, and clinical case studies, fostering a translational approach from laboratory research to clinical application. This resource benefits researchers, clinicians, and students by offering insights into cutting-edge nanomedicine, fostering interdisciplinary collaboration, and guiding future innovations in personalized cancer therapy and commercialization pathways.

  • Nanocarrier-Based Immunotherapy

    Emerging Frontiers in Cancer
    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Nanocarrier-Based Immunotherapy: Emerging Frontiers in Cancer explores innovative nanotechnology approaches to enhance cancer immunotherapy. This comprehensive volume addresses the design, mechanisms, and clinical potential of nanocarriers such as polymeric nanoparticles, liposomes, dendrimers, exosomes, and inorganic nanomaterials in modulating immune responses against tumors. The book provides in-depth coverage of foundational principles, recent advancements, and translational strategies. In addition, it discusses how nanocarriers improve targeted delivery, overcome tumor immune evasion, and enable combination therapies.Chapters highlight cutting-edge topics like AI integration, safety profiles, and regulatory considerations, offering a multidisciplinary perspective. Designed for an academic audience, this resource facilitates understanding of nanomedicine’s role in cancer treatment. It equips researchers, clinicians, and students with scientific insights, novel strategies, and practical solutions to accelerate the development of next-generation immunotherapies.

  • Synthetic Biology in Medicine

    Tools and Transformative Therapies
    • 1st Edition
    • Xie Zhen
    • English
    Synthetic Biology in Medicine: Tools and Transformative Therapies covers the design and optimization of artificial biological components, gene editing systems, principles for designing and constructing artificial gene circuits, cell engineering, delivery systems of artificial biomolecules, and the prospects and challenges of synthetic biology technologies applied in drug development. The book contains many application cases related to clinical practice and industry, offering references for solving industrial pain points.

  • Health Impacts of Climate Change

    A Global Perspective
    • 1st Edition
    • Mohammad Hadi Dehghani + 2 more
    • English
    Health Impacts of Climate Change: A Global Perspective confronts the most urgent reality of our time: the climate crisis is, at its core, a health crisis. Drawing from the latest research in climate science, public health, and policy, this book offers a comprehensive, interdisciplinary look at how global warming is already endangering lives—and what can be done to protect them. Readers will gain a deep understanding of direct health threats like heatstroke, air pollution, and disaster-related trauma, as well as the less visible dangers: rising zoonotic diseases, crop failures leading to malnutrition, and mental health challenges driven by climate-induced displacement.What sets this book apart is its unwavering focus on equity. It explores how climate change disproportionately impacts the most vulnerable—low-incom... communities, people in the Global South, and marginalized groups—who contribute the least to global emissions but bear the brunt of the damage. Through case studies, personal narratives, and policy analysis, the book amplifies frontline experiences and calls for climate justice as an essential part of any effective health response. From practical strategies for healthcare professionals to frameworks for policymakers, this book empowers a wide range of readers—from students and researchers to community leaders and concerned citizens.

  • Translational Medicine in Dry Eye Disease

    A Comprehensive Clinical and Scientific Strategy
    • 1st Edition
    • Marco Zeppieri + 2 more
    • English
    Translational Medicine in Dry Eye Disease: A Comprehensive Clinical and Scientific Strategy offers clinicians, researchers, and healthcare professionals a comprehensive, multidisciplinary resource that translates the latest scientific advances into practical strategies for diagnosing, managing, and treating dry eye disease. By bridging laboratory research and clinical application, this book equips end users with up-to-date insights, innovative diagnostic tools, and evidence-based therapies to improve patient outcomes in the rapidly evolving field of ocular surface health.

  • Ecophysiology and Microplastics in Marine Molluscs

    • 1st Edition
    • Youji Wang
    • English
    Ecophysiology and Microplastics in Marine Molluscs provides a comprehensive examination of emerging microplastic pollutants and their physiological impacts on marine mollusks. The book collates emerging research on the biological impacts of microplastics on mollusks, a key taxon of significant commercial and ecological import. Written by an international team of experts, it begins with an overview of microplastics and their presence in marine environments. It then delves into how microplastics are ingested and processed by mollusks, their internal accumulation, and the resulting impacts on metabolism, immunity, development, reproduction, and behavior.The book also examines the broader implications for aquaculture and suggests strategies for mitigating microplastic pollution in marine farming, making it an invaluable resource for students, young researchers, and professionals in the fields of marine biology, ecotoxicology, and aquaculture.

  • PROTACs Overcome Resistance to Cancer Therapies

    • 1st Edition
    • Daohong Zhou
    • English
    PROTACs Overcome Resistance to Cancer Therapies explores the transformative potential of proteolysis targeting chimeras (PROTACs) in addressing one of oncology’s greatest challenges: drug resistance. Edited by Dr. Daohong Zhou, this volume brings together leading experts to present the latest advances in targeted protein degradation for cancer treatment. The book covers foundational principles of PROTAC design, mechanisms of action, and their advantages over traditional small molecule inhibitors. It delves into strategies for targeting undruggable proteins, overcoming resistance in various cancer types, and mitigating emerging resistance to PROTACs.Case studies include BCL-xL, KRAS, STAT3, and EGFR-targeting PROTACs, with insights into clinical translation and precision medicine. This resource equips cancer researchers, oncologists, and pharmaceutical scientists with practical guidance and cutting-edge knowledge. It serves as both a reference and a roadmap for developing next-generation therapeutics, making it essential for those advancing cancer drug discovery and translational medicine.

  • Digital Oncology Rehabilitation

    Integrating Technology into Cancer Rehabilitation and Palliative Care
    • 1st Edition
    • Manpreet Kaur + 3 more
    • English
    Digital Oncology Rehabilitation: Integrating Technology into Cancer Rehabilitation and Palliative Care reimagines cancer recovery through the lens of digital innovation. This edited volume bridges clinical expertise and technological advancement to transform physiotherapy and palliative care in oncology. The book explores AI-driven personalization, telephysiotherapy, wearable sensors, robotics, and predictive analytics, offering practical frameworks for remote assessment, symptom monitoring, and adaptive rehabilitation. Sections are supported by real-world case studies and ethical implementation strategies.Academics... clinicians, and researchers will benefit from a comprehensive, evidence-based guide that merges compassionate care with cutting-edge tools, thus empowering them to improve quality of life, create functional outcomes, and provide equitable access for cancer survivors and palliative patients.

  • Bioinformatics Essentials II

    From Multi‑omics to AI – Methods, Workflows, and Translational Applications
    • 1st Edition
    • Syed Mudasir Ahmad + 2 more
    • English
    Bioinformatics Essentials II, From Multi‑omics to AI – Methods, Workflows, and Translational Applications offers a comprehensive guide to modern bioinformatics, focusing on best-practice workflows for multi-omics data analysis and AI-assisted discovery. Designed for learners and early-career researchers, it bridges foundational knowledge with cutting-edge applications. The book covers experimental design, sequencing technologies, and core omics workflows including transcriptomics, proteomics, metabolomics, and epigenomics. Advanced chapters explore single-cell and spatial omics, multi-omics integration, AI/ML applications, and environmental bioinformatics.Each chapter includes learning objectives, worked examples, toolbox comparisons, and reproducible code. This resource empowers students, faculty, and applied researchers to confidently analyze complex datasets and translate findings into agriculture, health, and environmental solutions. Its modular structure and companion website enhance usability in both coursework and independent study.

  • Mannose Binding Lectin Associated Serine Proteases

    Structure, Function and Therapeutic Implications
    • 1st Edition
    • Krishnan Hajela
    • English
    Mannose Binding Lectin Associated Serine Proteases: Structure, Function and Therapeutic Implications provides a comprehensive overview of MASP-1, MASP-2, and MASP-3, highlighting their roles in immune defense, disease mechanisms, and therapeutic intervention. This book covers the molecular structure and catalytic mechanisms of these key serine proteases, emphasizing their involvement in the lectin pathway of complement activation as well as their emerging functions in coagulation and bradykinin pathways. Chapters detail the biology of animal lectins and collections, classical and alternative complement pathways, and specific biochemical activities of MASP-1, MASP-2, and MASP-3.Readers will find in-depth discussions on the clinical significance of MASP gene polymorphisms and serum levels, and more. Special focus is given to the application of MASP-2 inhibitors in the management of complications such as hematopoietic stem-cell transplantation-asso... thrombotic microangiopathy (HSCT-TMA). This book is an essential resource for researchers in immunology, biochemistry, and molecular medicine, as well as clinicians seeking to advance their understanding of complement biology and the therapeutic potential of targeting the lectin pathway.

  • Euphorbiaceae Family Oriented Drug Discovery

    Exploration of Isolation, Identification, Total Synthesis, and Drug Discovery Based on Natural Products from Euphorbiaceae Family
    • 1st Edition
    • Bingjie Li + 1 more
    • English
    Euphorbiaceae Family Oriented Drug Discovery, Exploration of Isolation, Identification, Total Synthesis, and Drug Discovery Based on Natural Products from Euphorbiaceae Family, a volume in the Drug Discovery Opinions series, aims to comprehensively explore the isolation, identification, synthesis, and drug discovery based on natural products derived from the Euphorbiaceae family. Focused on the isolation, identification, synthesis of bioactive compounds, and drug discovery techniques, the contents of the book are organized into ten chapters. The book opens with an introduction to the Euphorbiaceae family, its botanical overview, medicinal significance, and the importance of exploring its natural products for drug discovery.The next chapters focus on specific techniques for identification and synthesis of natural products, cover the antitumor activities and mechanisms of action of natural products, and discuss the specific antimicrobial properties and mechanisms of action. Final sections discuss anti-inflammatory properties, pharmacology, drug discovery processes for Euphorbiaceae Natural Products, and describe challenges and future directions in research. The final chapter presents final considerations, summarizing key findings and insights from the book.

  • Lipid Lowering Combination Therapy for Dyslipidemia

    • 1st Edition
    • Maciej Banach
    • English
    Lipid Lowering Combination Therapy for Dyslipidemia provides clinicians, researchers, and healthcare professionals with practical, up-to-date guidance on the diagnosis and management of lipid disorders using combination therapies. Aimed at lipidologists, cardiologists, endocrinologists, and primary care providers, this book covers epidemiology, current guidelines, and the latest advances in drug therapies—including statins, PCSK9 inhibitors, and novel agents. Featuring expert insights, case studies, and clear recommendations, it is an essential resource for optimizing patient care and improving cardiovascular outcomes in those with dyslipidemia.

  • The Neurobiological Underpinnings of Addiction Medicine

    Focusing on Novel Approaches
    • 1st Edition
    • Mohammad Shabani + 3 more
    • English
    The Neurobiological Underpinnings of Addiction Medicine: Focusing on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and innovative strategies for treatment. This book begins by examining the crucial role of the microbiome and the gut-brain axis in various substance use disorders, including opioid, alcohol, neurostimulant, and cannabis use disorders. It highlights how gut health can significantly influence addiction behaviors and treatment outcomes. Following this, the second section discusses the interplay between addiction and neuropsychiatric disorders such as depression, anxiety, schizophrenia, ADHD, bipolar disorder, PTSD, and OCD.This section emphasizes the impact of neurotransmitter systems and intracellular pathways on the development and persistence of these disorders. The final section introduces cutting-edge methodologies reshaping addiction research, including multi-OMICS approaches and the implications of CRISPR-Cas9 technology. By integrating these diverse topics, this book offers vital insights for clinicians and researchers alike.

  • Health Geography

    Theories, Methods, and Case Studies
    • 1st Edition
    • Peng Jia
    • English
    Health Geography: Theories, Methods, and Case Studies examines the interdisciplinary domain of health geography, systematically integrating geographical science with public health paradigms. The book provides an in-depth analysis of the theoretical foundations, methodological innovations, and practical implications of health geography. Special emphasis is placed on employing geo-spatial technologies, such as Geographic Information Systems (GIS) and remote sensing to enhance disease prevention, health risk assessments, and healthcare resource allocation.By fostering an integrative dialogue among geography, epidemiology, and advanced technological approaches, the book addresses contemporary public health challenges from local to global scales. The book includes over 50 international case studies addressing infectious and chronic diseases, and health resource allocation.

  • Cold-Adapted Enzymes

    Biochemistry and Biotechnology
    • 1st Edition
    • Diego Gomez-Casati + 1 more
    • English
    Cold-Adapted Enzymes: Biochemistry and Biotechnology, the latest release in the Foundations and Frontiers of Enzymology series, provides a detailed investigation into enzymes that adapt to cold environments. The book covers the catalytic, structural, and regulatory properties of this type of enzyme and the potential advances in their biotechnological applications. Topics covered include the evolution of enzymes in cold environments, enzymes involved in carbohydrate metabolism (such as xylanases, B-galactosidase, and B-glucosidase), cold-adapted enzymes in lipid metabolism (such as esterases and lipases), and redox enzymes. In addition, the book also explores bacterial cold-adapted enzymes and those from organisms in extreme environments like Antarctica.Recombina... expression methods, protein engineering, and computational approaches are also featured. This book offers a complete overview of cold-adapted enzymes, making it a useful reference for researchers across a range of interdisciplinary fields, including biochemistry, enzymology, biotechnology, molecular evolution, structural biology and microbiology.

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