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Books in Life sciences

    • Cutting-Edge Nanocarrier-Based Strategies in the Management of Leukaemia

      • 1st Edition
      • Devesh U. Kapoor + 2 more
      • English
      Cutting-edge Nanocarrier-Based Strategies in the Management of Leukaemia addresses the importance of nanocarriers in leukemia treatment. The book explores advancements in nanotechnology, highlighting therapies like siRNA, miRNA, and gene therapy that improve patient outcomes. Sections provide an introduction to leukemia, covering its epidemiology and risk factors, discuss innovative therapies and the use of various nanocarriers, such as polymeric nanoparticles, liposomes, dendrimers, and hydrogels, and discuss precision medicine, AI in leukemia care, and strategies to overcome treatment resistance. The book is enriched with tables, figures, and images, giving healthcare providers, including physicians, immunologists, oncologists, and pharmacists an invaluable resource on cutting-edge therapies.
    • Protein-Based Nanoparticles in Drug Delivery

      • 1st Edition
      • Prashant Kesharwani
      • English
      Protein-based Nanoparticles in Drug Delivery is a comprehensive book aimed at pharmaceutical scientists and researchers both in academia and corporate environments focused on nanotechnology drug delivery and pharmaceutical-relat... disciplines. The book covers the design and characterization of various protein nanoparticles, sheds light on the power of an endogenous substance as a drug delivery system, and highlights the possible future trends in the use of protein-based drug delivery. It covers in-depth novel applications of protein-based drug delivery from fundamental to most current use cases. The book comprises three parts. Part one is devoted to the foundations of protein-based drug delivery, including nanocarriers development, drug encapsulation, targetability, and in vivo properties. Part two explores the applications of protein-based nanoparticles in drug delivery, covering topics such as protein nanoparticles in cancer therapy, genetic material delivery, and nanocarriers based on milk protein, silk, and gliadin. Part three addresses recent advances and regulatory aspects of protein-based nanoparticles in drug delivery, including clinical translation, challenges, biological toxicity, and environmental hazards associated with protein-based nanoparticles. Protein-based Nanoparticles in Drug Delivery provides a complete journey of protein-based drug delivery, offers an in-depth understanding of the design and characterization of various protein nanoparticles, and highlights possible future trends in this field. Pharmaceutical scientists will benefit from the novel applications of protein-based nanoparticles drug delivery approaches in the biological field. Nanotechnologists, biologists, chemists, physicists, engineers, and clinicians will also benefit from the foundational content provided as a basis to support communication and tackle the multidisciplinary challenges associated with research in this exciting field.
    • Molecular Mechanisms of Spermatogenesis

      • 1st Edition
      • Volume 168
      • English
      Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.
    • RED: Women's Health From Menarche to Menopause

      • 1st Edition
      • Diana Vaamonde + 3 more
      • English
      RED: Women’s Health and Wellness from Menarche to Menopause provides a holistic look at women’s health and wellness, interpreting contemporary medical and behavioral science into an accessible and engaging format to address biological, psychological, and sociocultural changes and challenges women experience as they move from menarche to menopause. This is a unique book with a fresh perspective of using lifestyle modifications and emotional support as adjunctive medicine therapies. It encompasses a novel reference useful for graduates, professors, researchers, healthcare professionals, and anyone interested in this field.
    • Epigenetic Mechanisms in Brain Physiology and Disorders

      • 1st Edition
      • Moshe Szyf + 1 more
      • English
      Epigenetic Mechanisms in Brain Physiology and Disorders provides a comprehensive summary of epigenetic mechanisms in brain development, from embryogenesis to aging, brain physiology and pathology. It discusses the role DNA methylation plays in regulating genomic functions, which in turn guide brain function. The book explores the epigenetic role in cell type differentiation, epigenetic processes in memory, learning, and neuronal functioning, the role of DNA methylation and other epigenetic mechanisms in sleep, feeding and metabolic control, sex, temperature regulation, and cardiovascular and blood pressure regulation. It further explores the role of epigenetic processes in neuropsychiatry disorders, neurological disease and behavioral disorders, as well as epigenetic diagnostics and therapeutics.
    • Pharmaceutical QbD with Design of Experiments

      Statistical Tools and Applications in Drug Delivery Systems
      • 1st Edition
      • Khushwant Yadav
      • English
      Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.
    • Advances in Immunology

      • 1st Edition
      • Volume 168
      • English
      Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.
    • Deep Learning Applications in Neuroinformatics

      Advances, Methods, and Perspectives
      • 1st Edition
      • Karthik Ramamurthy
      • English
      Deep Learning Applications in Neuroinformatics: Advances, Methods, and Perspectives explores how deep learning revolutionizes neuroinformatics, covering the latest methods and applications of deep learning in analyzing neuroimaging data from EEG, MRI, PET, and more. The book addresses critical neurological disorders like Alzheimer’s disease, Mild Cognitive Impairment, Stroke, and Autism Spectrum Disorder, bridging the gap between neuroscience and artificial intelligence. It is an ideal resource for researchers, practitioners, and students with insights from leading experts.
    • Nanotherapeutics for Treating Neurodegenerative Disorders

      • 1st Edition
      • Manish K. Chourasia + 3 more
      • English
      Nanotherapeutics for Treating Neurodegenerative Disorders reviews the complex landscape of neurodegenerative disorders, outlining the nuances of treatment strategies and the imperative role of nanotechnology in revolutionizing therapeutic interventions. From explaining the transport mechanisms of the Blood-Brain Barrier to unveiling the therapeutic potential of stem cell-derived nanocarriers, each chapter offers invaluable insights into the diverse array of nanotherapeutic approaches helping to reshape the landscape of neurological healthcare. By consolidating current updates on advanced targets-based nanotherapeutics, this book provides a comprehensive resource for neurodegenerative diseases converge.Whether seeking to unravel the complexities of mitochondrial dysfunction or to harness the potential of nanocarriers for targeted genetic material delivery, readers will find themselves equipped with the tools to navigate the forefront of neurotherapeutic innovation.
    • Immunomodulators

      • 1st Edition
      • Volume 151
      • English
      Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.