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Books in Pharmaceutical sciences

Elsevier's Pharmaceutical Sciences collection helps pharmaceutical scientists striving to optimize drug design and improve healthcare outcomes by offering comprehensive coverage of every aspect of drug development, integrating disciplines like organic chemistry, biology, and biotechnology. Focused on safety, efficacy, and formulation design, it includes specialized fields such as Clinical Pharmacology and Translational Research, providing valuable insights into the latest advancements in drug discovery.

  • Harnessing Endogenous Mechanisms for Targeted Drug Delivery

    • 1st Edition
    • Anisha A. D’Souza + 2 more
    • English
    Harnessing Endogenous Mechanisms for Targeted Drug Delivery presents a comprehensive exploration of the evolving landscape of targeted drug delivery, emphasizing the strategic utilization of the body's intrinsic biological pathways. This authoritative two-volume reference addresses the critical need for precision in therapeutic delivery, overcoming physiological, anatomical, and immunological barriers through innovative endogenous mechanisms. By integrating foundational concepts with advanced methodologies, the work underscores the transition from traditional passive and active targeting to sophisticated endogenous strategies that enhance drug specificity and efficacy.The text systematically examines the multifaceted challenges inherent in drug delivery, including detailed analyses of in vivo barriers such as the blood-tumor barrier, blood-brain barrier, ocular, pulmonary, and gastrointestinal obstacles, as well as cellular and intracellular impediments. It further elucidates endogenous stimuli-responsive systems, nutrient transporter exploitation, glyco-targeting, and stealth peptide modifications. Comprehensive coverage extends to drug conjugates, protein corona phenomena, and cell-based delivery platforms encompassing stem cells, leukocytes, erythrocytes, and platelets. The series also addresses extracellular vesicles, viral vectors, and plant virus-based carriers, culminating in critical discussions on manufacturing complexities, regulatory considerations, and clinical translation challenges.This definitive resource is indispensable for graduate students, postdoctoral researchers, and professionals in academia and industry engaged in targeted drug delivery research and development. By providing an in-depth understanding of endogenous targeting mechanisms and their translational potential, the book fosters innovation and supports the advancement of precision therapeutics with the goal of improving patient outcomes.

  • Handbook of Pharmaceutical Wet Granulation

    Theory and Practice in a Quality by Design Paradigm
    • 2nd Edition
    • Ajit S. Narang + 1 more
    • English
    Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm, Second Edition offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. This completely revised and updated edition features five new chapters covering new AI tools applied to scaling up granulation processes, model drive design, machine learning models for granule property prediction, design and scale up of fluid bed granulation, and process analytical methods. This book is the prefect reference for pharmaceutical manufacturing professionals. Academic researchers will benefit from the practical advice provided by the editors and chapter authors.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 47
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 47, first published in 1977, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered include ADRs, ADEs and SEDs: A Bird’s Eye View, Lithium, Drugs of abuse, Side effects of drugs used in the treatment of Alzheimer's disease, Sedatives and hypnotics, Antipsychotic agents, Anti-epileptic Medications, Side effects of opioid analgesics and narcotic antagonists, Anti-inflammatory and antipyretic analgesics and drugs used in gout, Side effects of local anesthetics and therapeutic gases, and more.Other sections covered include Antihistamines (H1 receptor antagonists), Drugs that act on the respiratory tract, Positive inotropic drugs and drugs used in dysrhythmias, Beta adrenergic antagonists and antianginal drugs, Drugs acting on the cerebral and peripheral circulations, Antihypertensive drugs, and much much more.

  • Functionalized Drug Delivery Systems

    • 1st Edition
    • Umesh Gupta + 1 more
    • English
    Functionalized Drug Delivery Systems delves into the potential of various functionalized drug delivery systems, such as polymeric micelles, dendrimers, metallic nanoparticles, and SMEDDS. It offers a comprehensive guide from basic concepts to advanced surface engineering techniques. The book covers liposomes, dendrimers, metal nanoparticles, polymeric micelles, niosomes, and ethosomes, concluding with a chapter on the regulatory framework. This invaluable resource is perfect for pharmaceutical researchers and graduate students keen on advancing their understanding and application of these innovative drug delivery methods. The book also provides consolidated literature reviews, making it a foundational text for new researchers.Its chapters are dedicated to specific techniques, offering detailed insights into each method. Readers will gain knowledge on improving drug absorption and targeted delivery, supported by practical examples and case studies. The final chapter on regulatory frameworks ensures compliance and best practices in developing functionalized drug delivery systems. This book is an essential read for anyone in the field of pharmaceutical research.

  • Fundamentals and Design of Drug Delivery Systems

    A Textbook with Lab Activities
    • 1st Edition
    • Wujie Zhang
    • English
    Fundamentals and Design of Drug Delivery Systems: A Textbook with Lab Activities is an essential resource for pharmaceutical sciences and engineering students. Covering all key concepts related to drug delivery courses, it introduces basic pharmacology, barriers to drug delivery, drug targeting, and novel drug delivery systems. Design considerations and approaches are thoroughly illustrated. The textbook reflects nanotechnology in various chapters and includes practical lab activities, providing a comprehensive understanding of drug delivery systems, experimental design, and data analysis. It is ideally suited for upper-undergraduate and graduate courses.In addition to the foundational material, the textbook delves into cutting-edge topics such as biomimetic drug delivery systems, targeted delivery systems, stimuli-responsive systems, and micro/nano-robots-ba... drug delivery systems. Emerging fields like cell therapy, artificial intelligence (AI) in drug delivery, and 3D printing-based systems are also explored. Professionals in the Pharma industry will benefit from the innovative concepts and platforms presented, making it a valuable addition to their resources.

  • Dissipative Particle Dynamics

    Fundamentals and Applications in Soft Matter Science and Engineering
    • 1st Edition
    • Alexander V. Neimark + 1 more
    • English
    Dissipative Particle Dynamics: Fundamentals and Applications in Soft Matter Science and Engineering comprehensively presents the fundamentals of dissipative particle dynamics (DPD) theoretical formulations and computational strategies, providing practical guidance on the application of DPD models to various colloidal and interfacial phenomena involving phase separations, self-assembly and transport in complex fluids, polymeric, surfactant, nanoparticle, and biological systems. In addition, the book contains instructive advice on efficient implementation of the DPD models in open-source computational packages. Since the introduction of the principles of DPD methodology, multiple efforts have been made to improve the computational basis of DPD, and to devise advanced versions and modifications. There are numerous research papers on this topic, but no books until now. Readers will find this to be a comprehensive reference source of multifaceted, interdisciplinary applications that provides practical guidance for efficient computational implementation.

  • Inorganic Biomaterials for Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 2 more
    • English
    Inorganic Biomaterials for Drug Delivery covers a wide range of inorganic biomaterial types and their properties, from traditional materials like ceramics, metallics, and bioglasses to novel composites and nano-engineered inorganic biomaterials. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science.

  • NanoPDT

    Nanomaterials-Enhanced Photodynamic Therapy
    • 1st Edition
    • Saeid Moghassemi + 2 more
    • English
    NanoPDT: Nanomaterials-Enhanc... Photodynamic Therapy covers extensively the therapeutic potential of multifunctional nanosystems that has made so much progress within the biomedical and pharmaceutical research communities over recent decades. Traditional photodynamic therapy (PDT), however, faces several limitations, primarily due to the hydrophobic nature of photosensitizers (PS), which tend to aggregate in aqueous environments, resulting in inadequate biodistribution and limited bioavailability. These constraints significantly reduce the efficacy of photodynamic therapy. The book also explores the most relevant combination therapies available. Four chapters are dedicated to the combination of NanoPDT with other approaches like Immunotherapy, Radiotherapy, chemotherapy, and photothermal therapy. NanoPDT: Nanomaterials-Enhanc... Photodynamic Therapy is an essential resource for pharmaceutical researchers, clinicians, and students in the fields of nanomedicine, oncology, and photodynamic therapy. It offers a thorough exploration of the latest advancements and future directions, providing valuable insights for those looking to enhance the efficacy and specificity of PDT through nanotechnology and its combined applications. The book's comprehensive coverage of both oncological and non-oncological applications makes it a crucial addition to the literature, bridging the gap between fundamental research and clinical practice.

  • Nanotechnology in Cosmeceuticals

    Advances, Challenges and Future Perspectives
    • 1st Edition
    • Chin Wei Lai + 1 more
    • English
    Nanotechnology in Cosmeceuticals: Advances, Challenges and Future Perspectives explores the fundamental principles of nanotechnology in cosmetics required to understand chemistry related formulation and the dermatological effects of these products. This book by provides an in-depth analysis of nanotechnology in cosmeceuticals, covering pharmaceutical, chemical, and toxicological aspects. The contents of this book are divided in seven parts. The first lays the foundations of cosmetics, and nanotechnology applications. The second part focuses no nano-metaloxides, including titanium, zinc, gold, silver and others. The third part covers carbon-based products in cosmeceuticals with chapters on graphene, nano-hydroxyapatite, and general carbon-based products. The next part focuses on nano-organics, nanocellulose and biodegradable materials. Part five is dedicated to formulations of liposomes, lipids in drug delivery. Part six covers recent trends, advances, applications and progress of nanotechnology and nano products in cosmeceuticals. The final part focuses on safety and toxicity aspects of nano-cosmeceuticals. Nanotechnology in Cosmeceuticals: Advances, Challenges and Future Perspectives is an ideal reference for pharmacologists, cosmetic scientists, and chemists in academic research and corporate settings looking into leveraging nanoscience to improve the performance of cosmetics. Dermatologists and food scientists may also benefit from the foundational content present in the first part of the book.

  • Ophthalmic Drug Delivery

    Advancement, Industrialization Prospect and Applications
    • 1st Edition
    • Neelesh Kumar Mehra
    • English
    Ophthalmic Drug Delivery: Advancement, Industrialization Prospect and Applications delves into the complexities and potential of scaling up and commercializing pharmaceutical innovations within ophthalmology. This book serves as a complete guide through research findings, industry insights, and regulatory guidelines, offering a thorough roadmap for the future of drug delivery systems targeting the eye. The importance of understanding the eye's physiology and anatomy is emphasized, laying the foundational knowledge necessary for developing effective treatments. The book continues by exploring various aspects such as novel formulations, fixed-dose combinations, and microbiological considerations.It also discusses cutting-edge research in reverse engineering approaches, the significance of Quality by Design (QbD), and the treatment of eye-related diseases like glaucoma, age-related macular degeneration, uveal melanoma, cataracts, and fungal keratitis. Corporate researchers will find the manufacturing insights particularly beneficial, making this an essential resource for professionals in the field of ophthalmic drug delivery.

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