Books in Pharmaceutical science general

Companion and Complementary Diagnostics

1st Edition
May 8, 2019
Jan Trøst Jørgensen
English
Paperback
9 7 8 0 1 2 8 1 3 5 3 9 6
eBook
9 7 8 0 1 2 8 1 3 5 4 0 2

Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies.

Quorum Sensing

1st Edition
April 6, 2019
Giuseppina Tommonaro
English
Paperback
9 7 8 0 1 2 8 1 4 9 0 5 8
eBook
9 7 8 0 1 2 8 1 4 9 0 6 5

Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

1st Edition
January 26, 2019
Prashant Kesharwani
English
Paperback
9 7 8 0 1 2 8 1 5 7 2 0 6
eBook
9 7 8 0 1 2 8 1 6 3 6 7 2

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions.

Biocontamination Control for Pharmaceuticals and Healthcare

1st Edition
November 30, 2018
Tim Sandle
English
Paperback
9 7 8 0 1 2 8 1 4 9 1 1 9
eBook
9 7 8 0 1 2 8 1 4 9 1 2 6

Biocontamination Control for Pharmaceuticals and Healthcare outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility. This key part of controlling risk escalation can lead to the contamination of medicinal products, hence necessary tracking precautions are essential. Regulatory authorities have challenged pharmaceutical companies, healthcare providers, and those in manufacturing practice to adopt a holistic approach to contamination control. New technologies are needed to introduce barriers between personnel and the environment, and to provide a rapid and more accurate assessment of risk. This book offers guidance on building a complete biocontamination strategy.

New Look to Phytomedicine

1st Edition
October 23, 2018
Mohd Sajjad Ahmad Khan + 2 more
English
Paperback
9 7 8 0 1 2 8 1 4 6 1 9 4
eBook
9 7 8 0 1 2 8 1 4 6 2 0 0

New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research.

Advanced Issue Resolution in Safety Pharmacology

1st Edition
September 5, 2018
Mary Jeanne Kallman + 1 more
English
Hardback
9 7 8 0 1 2 8 1 2 2 0 6 8
eBook
9 7 8 0 1 2 8 1 2 3 3 4 8

Advanced Issue Resolution in Safety Pharmacology not only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues.

Dosage Form Design Considerations

1st Edition
July 27, 2018
Rakesh Kumar Tekade
English
Hardback
9 7 8 0 1 2 8 1 4 4 2 3 7
eBook
9 7 8 0 1 2 8 1 4 4 2 4 4

Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

Dosage Form Design Parameters

1st Edition
July 25, 2018
Rakesh Kumar Tekade
English
Hardback
9 7 8 0 1 2 8 1 4 4 2 1 3
eBook
9 7 8 0 1 2 8 1 4 4 2 2 0

Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

Accelerated Predictive Stability (APS)

1st Edition
May 14, 2018
Fenghe Qiu + 1 more
English
Hardback
9 7 8 0 1 2 8 0 2 7 8 6 8
eBook
9 7 8 0 1 2 8 0 2 7 8 5 1

Accelerated Predictive Stability (APS): Fundamentals and Pharmaceutical Industry Practices provides coverage of both the fundamental principles and pharmaceutical industry applications of the APS approach. Fundamental chapters explain the scientific basis of the APS approach, while case study chapters from many innovative pharmaceutical companies provide a thorough overview of the current status of APS applications in the pharmaceutical industry. In addition, up-to-date experiences in utilizing APS data for regulatory submissions in many regions and countries highlight the potential of APS in support of registration stability testing for certain regulatory submissions. This book provides high level strategies for the successful implementation of APS in a pharmaceutical company. It offers scientists and regulators a comprehensive resource on how the pharmaceutical industry can enhance their understanding of a product’s stability and predict drug expiry more accurately and quickly.

Diagnostic and Therapeutic Applications of Exosomes in Cancer

1st Edition
May 9, 2018
Mansoor M. Amiji + 1 more
English
Hardback
9 7 8 0 1 2 8 1 2 7 7 4 2
eBook
9 7 8 0 1 2 8 1 2 8 0 4 6

Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.

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