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Books in Life sciences

Elsevier's Life Science collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

11-20 of 9877 results in All results

Adenoviral Vectors for Gene Therapy

  • 3rd Edition
  • February 1, 2025
  • David T. Curiel + 1 more
  • English
  • Hardback
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  • eBook
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Adenoviral Vectors for Gene Therapy, Third Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research.The fully updated and expanded third edition covers the basic biology of adenoviruses, highlights the potential use adenoviral vectors for the treatment of disease including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for vet applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine application and virotherapy, and oncolytic adenoviruses for anti-tumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

Retinoids in Development and Disease

  • 1st Edition
  • Volume 161
  • February 1, 2025
  • Norbert Ghyselinck + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 1 7 0 0 - 1
  • eBook
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This volume of Current Topics in Developmental Biology will focus on the role of retinoids during development and disease. Topics covered include the role of retinoic acid and its nuclear receptors in control of several developmental processes including germ cell differentiation/meiosis, somitogenesis, limb formation, hindbrain and spinal cord development, heart formation, eye and craniofacial development, and pancreas formation. Also covered is the role of various retinoids in adult processes including diseases of the visual cycle, obesity, and metabolism.

A History of Angiogenesis

  • 1st Edition
  • February 1, 2025
  • Gianfranco Natale + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 3 9 7 9 - 6
  • eBook
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A History of Angiogenesis: Discoveries, Research and the Therapeutic Potential presents a recent history of the discoveries in the angiogenic field that contribute very widely to the development of the anatomical knowledge of the process, the experimental models, and the new pharmacological approaches in different angiogenesis-related diseases. The book’s authors are from various key institutions and will deliver well-structured and well-designed chapters. The systematic presented information and knowledge will surely aid consistency and continuity. The multifaceted book is enriched with deep scientific contents. Each chapter will clearly define the historical steps, the emerging role during the years of new morphological findings, molecular pathways, and targets. Focus will be imparted on key challenges associated and the future directions.The history of angiogenesis research is an intriguing tool for discovering the answers to a wide array of queries arising in the biological and medical world. The scientist and students in the modern world need to understand how the angiogenic field reached the contemporary standard of knowledge which is associated with diverse benefit in the management of angiogenesis-related diseases. As a resource, this book will skilfully integrate all the key aspects related to angiogenesis and will be of immense help to the students, researchers, and industrial persons to explore the last two decades of angiogenesis discoveries and research.

The Heart and Vascular System

  • 1st Edition
  • February 1, 2025
  • Ramachandran S. Vasan + 1 more
  • English
  • Hardback
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  • eBook
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Heart disease is the leading cause of death, accounting for over 16% of global deaths since 2000, according to the World Health Organization. Now more than ever, it is crucial that students and professionals are equipped with the information to advance research and improve patient outcomes in cardiovascular medicine. The Heart and Vascular System: An Encyclopedia brings together foundational and advanced knowledge of the cardiovascular system into one comprehensive, succinct resource for students, instructors, researchers (basic, clinical, and population sciences), and clinicians across biomedical and medical sciences.With over 250 articles written and edited by top experts in the field, this book is the most reputable, easily searchable, digital and e-accessible resource on the heart and vascular system.

Tendon Regeneration

  • 2nd Edition
  • February 1, 2025
  • Manuela E. Gomes + 5 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 9 1 6 - 9
  • eBook
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Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes was the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies.Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices. Contributions from scientists, clinicians, and engineers who are the leading figures in their respective field’s present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field.New coverage will include signaling pathways for tendon development, molecular mechanisms of tendinopathy, inflammation contribution to healing and pathology of tendons, tendon aging and degeneration, tendon models, and translational studies for tendon regenerative medicine.

Medical and Health Genomics of South Asia

  • 1st Edition
  • February 1, 2025
  • Dhavendra Kumar + 1 more
  • English
  • Paperback
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  • eBook
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Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region.Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

Human Reproduction

  • 1st Edition
  • February 1, 2025
  • Marc yeste
  • English
  • Hardback
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  • eBook
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Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

Microbiota-Gut-Brain Axis and CNS Disorders

  • 1st Edition
  • February 1, 2025
  • Neeraj Mishra + 1 more
  • English
  • Paperback
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  • eBook
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Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain-axis in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain-axis modulations.Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others. The publication will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut, microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.

The Three Functional States of Proteins

  • 1st Edition
  • February 1, 2025
  • Timir Tripathi + 1 more
  • English
  • Paperback
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  • eBook
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Traditionally, different states of proteins have been defined based on their structures and functions. However, it is becoming increasingly clear that these criteria may not be sufficient to capture the complex properties of these molecules and that definitions based on thermodynamics and kinetics could be more appropriate. Emerging evidence indicates that under physiological conditions, most proteins can sample the native, droplet, and amyloid states. These states contribute to different cellular functions in accordance with their physical and structural properties.The native monomeric or oligomeric state of a protein is typically the most frequently observed state under cellular conditions. The biological functions of proteins are associated with this native state. Proteins in this functional state can be highly structured or intrinsically disordered (i.e., exist as highly dynamic structural ensembles of interconverting conformations), or they can combine features of order and disorder.The amyloid state with its cross-β structure is a solid-like condensed state that is thermodynamically stable at the cellular concentrations of proteins, and therefore its formation tends to be irreversible. Although many known examples of amyloids are related to the pathogenesis of various human diseases, functional amyloids are found in all kingdoms of life.The droplet or phase-separated state is a liquid-like condensed state formed by the non-stoichiometric assembly of protein molecules, often via interaction with nucleic acids. This is the functional state of many membrane-less organelles, which are now considered major organizing elements of intracellular space.This book provides comprehensive coverage of these three protein states and their thermodynamics and kinetic properties. The book also considers their interactions and discuss how their internal organization as individual molecules and their collective organization as molecular assemblies are stabilized. It also discusses how these states are formed and examines the cellular functions associated with the specific states.

Grapevine

  • 1st Edition
  • Volume 113
  • February 1, 2025
  • Paula Filomena Martins Lopes
  • English
  • Hardback
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  • eBook
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Grapevine: Added-Value and Applications, Volume 111 in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on exciting and timely topics such as Biorefinery based bioproducts and future prospective of vineyard and winery waste, Side-streams of wine industry: insights and learned lessons for making real the vision of reliable pharmacological applications, Grapevine as a natural resource in the cosmetic industry, Biology of the main grapevine viruses and their effects on vine growth, yield, and grape chemical composition, Table grapes: Health implications and approaches to improve the quality during the cultivation, and more.Additional sections cover topics such as Controlling authenticity throughout the wine production chain and Wine consumption versus health: the dilemma.