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Books in Molecular biology cellular biology and genetics

Animal Models of Disease Part C

  • 1st Edition
  • Volume 192
  • February 1, 2025
  • Lorenzo Galluzzi + 3 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 2 2 4 2 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 2 2 4 3 - 6
Animal Models of Disease, Part C, Volume 192 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors, The current models unravel the molecular mechanisms underlying the intricate pathophysiology of Alzheimer’s disease using Zebrafish, Colitis mouse model, Matching model with mechanism: appropriate animal models for studying various aspects of diabetes pathophysiology, Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics, and much more.Additional sections cover Antimicrobial regime for gut microbiota depletion in experimental mice models, Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease, A model of intraperitoneal ovarian cancer to study tumor responses to radioimmunotherapy, Metallic nanoparticles biodistribution for the study of lymphoma in animal models, Stereotactic injection of murine brain tumor cells for neuro-oncology studies, Evaluating amyloid-beta aggregation and toxicity in transgenic Caenorhabditis elegans models of Alzheimer's disease, and much more.

Biotechnology

  • 3rd Edition
  • January 31, 2025
  • David P. Clark + 3 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 1 8 4 8 4 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 4 8 5 - 7
Biotechnology: The Technological Applications of Genetics and Genomics, Third Edition, approaches modern biotechnology from a molecular basis, discussing how the fields of genetics, molecular biology, microbiology, and biochemistry are merging their respective discoveries into the expanding applied field of biotechnology. Each chapter starts with basic concepts that develop into more specific and detailed applications, providing readers with a good image of possibilities and current limitations in the field and future research directions.This new edition has been fully revised and updated to include research advances, and has new chapters on artificial intelligence, genome editing, precision and personalized medicine, and more. This book is an invaluable resource to anyone interested in understanding what molecular biotechnology is as a scientific discipline, how research in this area is conducted, and how this technology may impact the future.

Immuno-oncology and immunotherapy Part C

  • 1st Edition
  • Volume 191
  • January 15, 2025
  • Lorenzo Galluzzi + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 9 6 2 0 - 8
Immuno-oncology and immunotherapy, Part C, Volume 191 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Extraction and quantification of histones from human cells, Expression and characterization of Phosphatidylserine-targeting antibodies for biochemical and therapeutic applications, ILC differentiation from HSCs in vitro, Methods to expand human Treg cells and assay their function, Monitoring rapid activation of human gamma/delta T cells by multicolor flow cytometry, Methods to induce T cell exhaustion in vitro, Ex vivo assessment of human neutrophil motility and migration, and much more.Additional chapters focus on Flow cytometry-based monitoring of myeloid-derived suppressor cells in the peripheral blood of patients with solid tumors, Deciphering human blood and tumor neutrophil heterogeneity: Methods for isolation and assessing suppression of T-cell proliferation, Splenocyte anticancer citotoxicity assessment after prophylactic vaccination or drug treatment of tumor-bearing mice, Therapeutic treatment of tumor-bearing mice with drug-killed cancer cells: a method to confirm immunogenic cell death and assess its therapeutic effectiveness, and much more.

Artificial Intelligence in Microbiology: Scope and Challenges volume-II

  • 1st Edition
  • Volume 56
  • January 15, 2025
  • Akanksha Srivastava + 1 more
  • English
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 9 6 2 7 - 7
Artificial Intelligence in Microbiology: Scope and Challenges, Volume-II, Volume 56 covers changes due to the emergence of Artificial Intelligence (AI). AI is being used to analyze massive data in a predictable form, about the behavior of microorganisms, to solve microbial classification-related problems, and more. Chapters include Taking on the resistance: AI and battle against antimicrobial resistance, AI-powered insights into microbial communities for bioremediation strategies, Efficient and cost-effective production of viral vaccines via AI, Production and development of novel drug targets through AI, Use of AI in neuroscience, Role of Artificial Intelligence in studying metagenomics of Microbes: Decoding the microbial Sphere, and more.Other chapters explore Exploring the functional role of bacterial proteins via AI, Application of AI in Aquaculture/Fisheries: Disease identification, detection, diagnosis, drug development, Artificial Intelligence in drug discovery & development; scope and challenges, Production of bacteriocins by AI: as food preservative, Exploring the Role of Artificial Intelligence in the Microbial remediation of heavy metals, Uses of Artificial Intelligence in the Agricultural Pest Management, Microbial fermentation processes using Artificial Intelligence, and more.

Kaufman’s Atlas of Mouse Development Supplement

  • 2nd Edition
  • November 30, 2024
  • Gillian Morriss-Kay + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 2 3 7 3 9 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 3 7 3 8 - 6
Kaufman's Atlas of Mouse Development Supplement, Second Edition continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems. The book explores the developmental origins of the organ systems, following the original atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. In this new edition, each chapter has been updated to include the latest research, along with while new chapters on the functional aspects of mouse and human heart development, the immune system, and the inner ear.These additions ensure an up-to-date resource for all biomedical scientists who use the mouse as a model species for understanding the normal and abnormal development of human systems.

Mitophagy in Health and Disease

  • 1st Edition
  • November 28, 2024
  • John J. Lemasters
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 2 6 0 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 2 6 1 - 0
Mitophagy in Health and Disease: Mechanisms, Health Implications, and Therapeutic Opportunities is a complete reference to this key cellular process involved in homeostasis. The book addresses the machinery and mechanisms of mitophagy, including an overview of mito-biogenesis and dynamics and specific types of mitophagy. Other sections cover mitophagy across the human lifespan, from development to aging, discussing the interplay between inflammation and several conditions. The final part covers therapeutic opportunities presented by targeting mitophagy, including inducers and inhibitors, targeting strategies, and studies specific to cardioprotection and neurodegenerative diseases prevention.This is the ideal reference for cellular and molecular biologists needing a consistent and thorough overview of the subject, as well as research physicians in areas where mitochondria play a key role.

Deep Learning in Genetics and Genomics

  • 1st Edition
  • November 28, 2024
  • Khalid Raza
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 7 5 2 3 - 4
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 7 5 2 4 - 1
Deep Learning in Genetics and Genomics: Vol. 2 (Advanced Applications) delves into the Deep Learning methods and their applications in various fields of studies, including genetics and genomics, bioinformatics, health informatics and medical informatics generating the momentum of today's developments in the field. In 25 chapters this title covers advanced applications in the field which includes deep learning in predictive medicines), analysis of genetic and clinical features, transcriptomics and gene expression patterns analysis, clinical decision support in genetic diagnostics, deep learning in personalised genomics and gene editing, and understanding genetic discoveries through Explainable AI. Further, it also covers various deep learning-based case studies, making this book a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning based approaches. This volume is not only a valuable resource for health educators, clinicians, and healthcare professionals but also to graduate students of genetics, genomics, biology, biostatistics, biomedical sciences, bioinformatics, and interdisciplinary sciences.

Deep Learning in Genetics and Genomics

  • 1st Edition
  • November 28, 2024
  • Khalid Raza
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 7 5 7 4 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 7 5 7 5 - 3
Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications, the intersection of deep learning and genetics opens up new avenues for advancing our understanding of the genetic code, gene regulation, and the broader genomics landscape. The book not only covers the most up-to-date advancements in the field of deep learning in genetics and genomics, but also a wide spectrum of (sub) topics including medical and clinical genetics, predictive medicine, transcriptomic, and gene expression studies. In 21 chapters Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications describes how AI and DL have become increasingly useful in genetics and genomics research where both play a crucial role by accelerating research, improving the understanding of the human genome, and enabling personalized healthcare. From the fundamentals concepts and practical applications of deep learning algorithms to a wide range of challenging problems from genetics and genomics, Deep Learning in Genetics and Genomics vol. 1, Foundations and Applications creates a better knowledge of the biological and genetics mechanisms behind disease illnesses and improves the forecasting abilities using the different methodologies described. This title offers a unique resource for wider, deeper, and in-depth coverage of recent advancement in deep learning-based approaches in genetics and genomics, helping researchers process and interpret vast amounts of genetic data, identify patterns, and make discoveries that would be challenging or impossible using traditional methods.

The Three Functional States of Proteins

  • 1st Edition
  • November 17, 2024
  • Timir Tripathi + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 1 8 0 9 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 1 8 1 0 - 1
The Three Functional States of Proteins explores how structured proteins, intrinsically disordered proteins, and phase separated proteins contribute to the complexity of cellular life, and offers insights into their roles in both health and disease. It discusses the latest research findings and highlight groundbreaking discoveries and innovative methodologies used to study these protein states.Traditionally, the different states of proteins have been defined based on their structures and functions. However, it is becoming increasingly clear that these criteria alone may not be sufficient to capture the complex and multifaceted properties of these molecules. Definitions based on thermodynamics and kinetics are now recognized as potentially more appropriate for comprehensively understanding protein states. Emerging evidence indicates that under physiological conditions, a majority of proteins possess the capability to exist in and transition between the native, droplet, and amyloid states. These distinct states play crucial roles in various cellular functions, influenced significantly by their physicochemical and structural properties. The book also considers the interactions among these states and discusses how their internal organization as individual molecules, as well as their collective organization as molecular assemblies are stabilized. Furthermore, it examines the processes by which these states are formed and the cellular functions associated with each specific state.

Mining Biomedical Text, Images and Visual Features for Information Retrieval

  • 1st Edition
  • November 15, 2024
  • Sujata Dash + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 4 5 2 - 2
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 4 5 1 - 5
Mining Biomedical Text, Images and Visual Features for Information Retrieval provides broad coverage of the concepts, themes, and instrumentalities of the important, evolving area of biomedical text, images, and visual features towards information retrieval. The book aims to encourage an even wider adoption of IR methods for assisting in problem-solving and to stimulate research that may lead to additional innovations in this area of research. Topics covered include Internet of Things for health informatics; data privacy; smart healthcare; medical image processing; 3D medical images; evolutionary computing; deep learning; medical ontology; linguistic indexing; lexical analysis; and domain specific semantic categories in biomedical applications. This is a valuable resource for researchers and graduate students who are interested to learn more about data mining techniques to improve their research work.