Books in Molecular biology cellular biology and genetics

Techniques in Protein Chemistry III

1st Edition
June 28, 2014
Ruth Hogue Angeletti
English
eBook
9 7 8 1 4 8 3 2 5 9 4 6 8

Techniques in Protein Chemistry III compiles papers presented at the Fifth Protein Society Symposium in Baltimore on June 22-26, 1991. This book discusses the protein and peptide recovery from PVDF membranes; high-sensitivity peptide mapping utilizing reversed-phase microbore and microcolumn liquid chromatography; and capillary electrophoresis for preparation of peptides and direct determination of amino acids. The TFMSA/TFA cleavage in t-Boc peptide synthesis; applications of automatic PTC amino acid analysis; and identification of O-glycosylation sites with a gas phase sequencer are also elaborated. This text likewise covers the conformational stability of the molten globule of cytochrome c and role of aqueous solvation in protein folding. This publication is useful to students and researchers interested in methods and research approaches on protein chemistry.

Transgenesis and Targeted Mutagenesis in Immunology

1st Edition
June 28, 2014
Horst Bluethmann + 1 more
English
eBook
9 7 8 1 4 8 3 2 9 6 4 9 4

Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for fresh observations and interpretations when designing future experiments.

In Vitro Methods in Cell-Mediated Immunity

1st Edition
June 28, 2014
Barry R. Bloom + 1 more
English
eBook
9 7 8 1 4 8 3 2 7 7 5 9 2

In Vitro Methods in Cell-Mediated Immunity focuses on methods for approaching cell-mediated immune responses in vitro. This book provides, in simplified in vitro systems, a basis for understanding the mechanism of the in vivo response and discusses useful and reliable in vitro tests for cell-mediated immune responses in humans, where in vivo testing is often not possible. The topics discussed include factors and activities produced in vitro by lymphocytes; biological implications of in vitro phenomena; and requirements and prospects for improved methodology. The leucocyte migration technique for in vitro detection of cellular hypersensitivity in man; proliferation of human blood lymphocytes stimulated by antigen in vitro; and virus plaque assay for antigen-sensitive are also elaborated in this text. This publication is a good reference for microbiologist and immunologists, including medical students researching on in vitro models for cell-mediated immune reactions.

Search and Discovery

1st Edition
June 28, 2014
Benjamin Kaminer
English
eBook
9 7 8 1 4 8 3 2 7 4 5 5 3

Search and Discovery: Tribute to Albert Szent-Györgyi is dedicated to Albert Szent-Györgyi and stems from a Symposium, ""Search and Discovery,"" held in his honor at Boston University School of Medicine. Szent-Györgyi, born in Budapest on September 16, 1893, established the Institute for Muscle Research at the Marine Biological Laboratory in 1947. His influence and impact extend beyond the confines of the laboratory. Throughout his life he was intensely concerned with the serious problems of mankind. He opposed Hitler and Stalin, and was outspoken against the involvement of the U.S. Government in the Vietnam War. Starting with recollections of Albert Szent-Györgyi by John T. Edsall of Harvard University, the remainder of the text is organized into six parts that cover the fields of Szent-Györgyi’s major contributions and interests: metabolism, vitamin C, molecular mechanisms of muscle contraction, submolecular biology and cell growth, and cancer; the social interrelations of science were also not neglected. These milestones form the basis of this volume.

Telomeres in Health and Disease

1st Edition
Volume 125
June 26, 2014
Rodrigo Calado
English
Hardback
9 7 8 0 1 2 3 9 7 8 9 8 1
eBook
9 7 8 0 1 2 3 9 7 9 0 9 4

This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field.

Regulated Cell Death Part A

1st Edition
Volume 544
June 24, 2014
Avi Ashkenazi + 2 more
English
Hardback
9 7 8 0 1 2 4 1 7 1 5 8 9
eBook
9 7 8 0 1 2 4 1 7 1 7 5 6

Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.

Redox and Cancer Part A

1st Edition
Volume 122
June 24, 2014
Kenneth D. Tew + 1 more
English
Hardback
9 7 8 0 1 2 4 2 0 1 1 7 0
eBook
9 7 8 0 1 2 4 2 0 1 7 6 7

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics — Volume 122 explores subjects related to redox, including: redox homeostasis in epithelial-derived cancers; reactive oxygen species in normal and tumor stem cells; and gamma-glutamyl transpeptidase and redox regulation.

Quantitative Imaging in Cell Biology

1st Edition
Volume 123
June 20, 2014
Jennifer Waters + 1 more
English
Hardback
9 7 8 0 1 2 4 2 0 1 3 8 5
eBook
9 7 8 0 1 2 4 2 0 2 0 1 6

This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric imaging, and counting molecules, are covered in detail. Practical chapters cover topics critical to getting the most out of your imaging system, from microscope maintenance to creating standardized samples for measuring resolution. Later chapters cover recent advances in quantitative imaging techniques, including super-resolution and light sheet microscopy. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come.

International Review of Cell and Molecular Biology

1st Edition
Volume 311
June 18, 2014
Kwang W. Jeon
English
Hardback
9 7 8 0 1 2 8 0 0 1 7 9 0
eBook
9 7 8 0 1 2 8 0 0 4 4 5 6

International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. Impact factor for 2012: 4.973.

Transgenic Animal Technology

3rd Edition
June 17, 2014
Carl A. Pinkert
English
Hardback
9 7 8 0 1 2 4 1 0 4 9 0 7
eBook
9 7 8 0 1 2 4 0 9 5 3 6 6

Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer — from molecular methods to whole animal considerations — for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students. This second edition incorporates updates on a variety of genetic engineering technologies ranging from microinjection and ES cell transfer to nuclear transfer in a broad range of animal modeling systems.

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