Skip to main content
Elsevier

Books in Molecular biology cellular biology and genetics

This collection offers insights into gene expression, cell signalling, and genetic regulation. Supporting researchers, clinicians, and students, it features advanced techniques, genetic engineering, and disease mechanisms, fostering innovations in personalized medicine, regenerative therapies, and molecular diagnostics.

  • Cerebellum Development and Disease

    • 1st Edition
    • Volume 167
    • English
    Cerebellum Development and Disease, Volume 167 offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. Chapters in this new release cover Olivocerebellar circuit development as a substrate for dystonia pathogenesis, Simply complex – that structure of the cerebellar neuronal lineage, Ontogenesis and diversification of cerebellar glia: a developmental perspective, Purkinje cell diversification: a blueprint for cerebellar development, patterning, and evolution, On the Emergence of Folding in the Cerebellum, Scaling and regeneration in the developing cerebellum, ASTN2 in ASD and Neurodevelopmental Disorders, and much more.Additional sections focus on Stem cell-derived in vitro models of human cerebellar development, Development of Spinocerebellar System within the Precerebellar Network, and Cerebellum evo-devo. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

  • Artificial Intelligence for Multi-omics Analysis Part A

    • 1st Edition
    • Volume 221
    • English
    Artificial Intelligence for Multi-omics Analysis, Part A, Volume 221 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as an Introduction to Artificial Intelligence in Multi-omics Analysis, Multi‐omics application in health and diseases, Artificial Intelligence in Genomics Analysis, Artificial Intelligence in Single-cell and Spatial Transcriptomics Data, Artificial Intelligence in the prediction of 3D chromatin structure and gene regulation, Artificial intelligence in Mass Spectrometry-based Proteomics, Integrating Artificial Intelligence into Metabolomics for Predicting Diseases, and more.Additional chapters cover Artificial Intelligence in Microbial Metagenomics, Artificial Intelligence in Interactomics, Artificial Intelligence Integration in Medical Imaging Data, AI in biomolecular structural data analysis, Artificial intelligence in Cryo-Electron Microscope data, Explainable artificial intelligence for multi-omics data, and Multi-Omics Cancer Stratification: from Statistical to Deep Learning Perspective.

  • Cell Death Part A

    • 1st Edition
    • Volume 205
    • English
    Cell Death, Part A, Volume 205 explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical sciences. Chapters in this new release include Methodologies for Monitoring Alkaliptosis in Cancer Cells, Protein-complementat... assay and DISC analysis, Detecting phosphorylated MLKL in murine tissues, Establishment of different cell death models (Apoptosis, Necroptosis, Pyroptosis), Implementation of the FENIX assay to determine anti-ferroptotic properties of test compounds, CRISPR-Cas9 knockout screens to identify drug resistance genes in Acute Myeloid Leukemia, and much more.Additional chapters cover Cell death assays for the detection of acute kidney tubular necrosis, Methods of cell death imaging by Incucyte and similar platforms, Super-resolution microscopy-based assessment of organellar redox-active iron distribution and its relevance for ferroptosis, Monitoring inflammasome activation by analyzing ASC specks and oligomerization, LPS-induced sepsis/ and TNF-induced SIRS (In vivo cell death models), Evaluating protease activation and inactivation of gasdermin cell death effectors, and Measurement of plasma membrane rupture via confocal microscopy.

  • Fundamentals of Molecular Structural Biology

    • 2nd Edition
    • Subrata Pal
    • English
    Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

  • Immunomodulators - Part A

    • 1st Edition
    • Volume 151
    • English
    Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.

  • Autophagy – Part A

    • 1st Edition
    • Volume 403
    • English
    Autophagy – Part A, Volume 403 explores the fundamental biological process of autophagy. Beginning with the historical discovery and molecular mechanisms of autophagy, the book delves into its regulation, physiological roles, and significance in maintaining cellular homeostasis. Chapters in this new release include Ciliophagy: Maintaining Primary Cilium Homeostasis to Prevent Cilium-Related Diseases, Unraveling the interplay of glycolysis, lactylation, and autophagy, Autophagy and Type 2 Diabetes: Bridging the Gap in Metabolic Health, Autophagy in Cancer Cachexia: From Mechanisms to Therapeutic Opportunities, Glycophagy: A Selective Autophagy Pathway for Glycogen Degradation, Role of Autophagy in Adipose Tissue: Implications for Metabolic Health, and more.

  • 2D and 3D Cellular Screening Models and AI Guided Analysis

    • 1st Edition
    • Volume 204
    • English
    2D and 3D Cellular Screening Models and AI Guided Analysis, Volume 204 explores the development, application, and comparative benefits of 2D monolayer cultures and 3D organoids, spheroids, and tissue-engineered constructs for biomedical research and drug discovery. Chapters in this new release include High throughput CellTiter-glo viability assessment, Assessing viability of cancer cell spheroids in 3D drug screening, 3D killing assay of cancer spheroids by cytotoxic T lymphocytes in anchored microfluidic droplets, Use of micropatterning for 3D cell culture, Use of microfluidic chip devices for assessing the effect of radiation on 3D cell culture models, and much more.Additional chapters cover A 3D model for assessing regulated cell death modalities, YOLO detection model for Cell Viability assessment, Bioinformatics and AI/ML approaches using multi-omics data to accelerate diagnosis and delivery of precision care, Automated image analysis and machine learning for the assessment of mitochondrial membrane potential, Assessing cancer cell heterogeneity in patient-derived tumoroids, Assessment of lysosomal drug sequestration and release using fluorescence microscopy, Assessment of T cell toxicity in ex-vivo models of cancer, Three-dimensional Organoid Screening using Leica Thunder Microscope, Using vascularized organoids-on-chip for assessing systemic drug delivery, and many more interesting and timely topics.

  • Epigenetic Regulation of Cancer - Part E

    • 1st Edition
    • Volume 400
    • English
    Epigenetic Regulation of Cancer, Part E, Volume 400 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic regulation of cancer, Phytochemicals with epigenetic properties and their role in melanoma therapy, Epigenetic Insights of MicroRNAs: Pioneering Cancer Detection via Advanced Biosensors, Epigenetic Regulation of Autophagy in Cancer: A Double-Edged Sword in Tumor Progression and Therapy Resistance, Epigenetic Regulation via Histone Modifications in Ovarian Cancer, The current findings and potential applications of breast cancer epigenetics, and much more.Other chapters cover the Application of bioinformatics and data science in studies of cancer epigenetics, and much more.

  • Cytoskeletal Proteins in Neurodegenerative Diseases

    • 1st Edition
    • Volume 150
    • English
    Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more. Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.

  • Unlocking the Secrets of Extracellular Vesicles and Exosomes

    A Journey into the Cutting-Edge Frontier of Cellular Communication
    • 1st Edition
    • Chandrashekhar Singh + 4 more
    • English
    Unlocking the secrets of extracellular vesicles and exosomes: A journey into the cutting-edge frontier of cellular communication provides a comprehensive overview of the latest advances and research on extracellular vesicles (EVs) and exosomes. The book begins with a historical introduction to the field and how this has evolved since EVs were first observed, before exploring their cellular mechanisms and approaches to study their isolation, characterization, and function. It then delves into exosomes in health and disease, considering their role across cancer, regenerative medicine, neurological disorders, and metabolic disorders, highlighting their potential as biomarkers for disease diagnosis. The book moves on to discuss cutting-edge technology for the engineering of EVs and exosomes, considering how the integration of AI, machine learning, and nanotechnology can be utilized to expand the therapeutic capabilities of EV and exosome-based applications. It then closes with chapters covering novel applications in nutraceutical and cosmetic production, and a look towards the future potential of EVs and exosomes. Unlocking the secrets of extracellular vesicles and exosomes offer a thorough exploration of EV and exosome research, covering various dimensions from basic science to clinical applications and future perspectives. It is an ideal guide for researchers working across a diverse range of disciplines, including cell biology, molecular biology, biotechnology, therapeutics, and biomedicine.

  • Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions

    • 1st Edition
    • Volume 728
    • English
    Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions, Volume 729 provides a broad snapshot of state-of-the-art methods for studying biological lipids and biomembranes. Sections in this new release cover De novo chemoenzymatic construction of lipid membranes, Photoaffinity labeling for cholesterol metabolism, Expression and Characterization of Phospholipase Cb and Ce enzymes, Assembling Retromer-coated membrane tubules for in vitro structure-function studies, Quantitative analysis of S-acylation, Inhibition of palmitoyltransferase... Exploiting protein lipidation to create peptide-based biomaterials, and much more.Additional sections discuss Optogenetic control of lipid-modifying enzyme activity using LOV domain insertions, Chemoproteomics approaches for inhibition of diacylglycerol kinases, Inhibition of sterol transfer protein function, Preparation of K-Ras4B containing synthetic modifications via expressed protein ligation, Regulation of lipin enzymes on membranes, Use of novel synthetic analogues to decipher the interactions of phosphatidic acids species, Analyzing lipid-nuclear receptor interactions, and much more.

  • Cell Shape and Position during Development

    • 1st Edition
    • Volume 166
    • English
    Cell Shape and Position during Development, Volume 166 provides a comprehensive overview of the fundamental roles that cell morphology and spatial organization play in the development of multicellular organisms. This volume brings together leading experts in developmental biology, cell biology, and biophysics to explore how cells acquire specific shapes. Chapters in this new release include Cell shape changes during sperm-egg interactions, Cell shape and position during organ development, Regulation of shape and position during asymmetric cell division, Cell shape dynamics during mouse peri-implantation development and embryo dormancy, Shaping the intestine: the role of cell morphology and spatial dynamics in development, and more.Additional sections Intermediate filaments in cell shape and position, Regulation of adult stem cell behavior by cytoskeletal dynamics and cell shape, Shape changes in gastrulation, and more.

  • Lipids and Membranes: Dynamics and Interorganelle Lipid Transport

    • 1st Edition
    • Volume 727
    • English
    Lipids and Membranes: Dynamics and Interorganelle Lipid Transport, Volume 728 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the book's chapters include topics such as Assay of phospholipid scrambling, Tracking lipid transport with bifunctional lipids, Tracking interorganelle lipid transport using genetically encoded mass tags, Molecular Dynamics Simulation of Lipid and Ligand Binding in ORD Domains, Imaging lipid droplet-organelle membrane contact sites using fluorogenic complementation, Studying interactions of amphipathic helices with lipid droplets, and more.Additional chapters cover Metabolic labeling of to trace changes in sphingolipid metabolism, Imaging intracellular lipid heterogeneity with fluorogen-activated coincidence sensing, Tagging lipoproteins in mycobacteria, Probes for studying sphingolipid dynamics, Measuring Flipper-TR Lifetime with Multiple Analysis Strategies, Reconstitution approaches to understanding cellular lipid dynamics, Prediction and characterization of the bacterial lipid handling machinery, From Molecular Dynamics to Cryo-EM: Imaging Liposomes in Silico, and much more.

  • Animal Models of Disease Part E

    • 1st Edition
    • Volume 203
    • English
    Animal Models of Disease, Part E, Volume 203 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer - Part B

    • 1st Edition
    • Volume 399
    • English
    Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part B delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Liquid biopsy approaches to capture minimal residual disease and therapy response in patients with early stage cancers, Identification of circulating biomarkers for cancer therapy-related cardiovascular toxicity, Extracellular Vesicles as Dynamic Biomarkers: Monitoring Therapeutic Responses and Drug Resistance in Cancer, and more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

  • Lipids and Membranes: Detection by Imaging and Lipidomics

    • 1st Edition
    • Volume 726
    • English
    Lipids and Membranes: Detection by Imaging and Lipidomics, Volume 727 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the chapters in this new release include Measurement of fatty acid esters of hydroxy fatty acids, Superresolution organelle imaging with lipophilic HIDE probes, Ultra-high resolution analysis of membrane lipids from 15N metabolically labeled mice, Superresolution lipid imaging with expansion microscopy, High-resolution phosphoinositide analysis in healthy versus disease cells, and much more.Additional chapters focus on Alkyne lipids as tracers of lipid metabolism, Imaging oxidative stress in biomembranes, Imaging the dynamics of phosphatidylinositol 4-phosphate metabolism, Lipidomics for studying sphingolipids in cell death, Non-invasive imaging of phosphoinositides with genetically encoded lipid biosensors, Profiling lipotypes at the single cell level in heterogenous populations, MS imaging of phosphoinositides, and much more.

  • Live Biotherapeutics: Advancing Microbial Medicine

    • 1st Edition
    • Volume 220
    • English
    Microbial therapeutics are rapidly reshaping modern medicine, with live biotherapeutics emerging as a promising frontier. By harnessing the power of beneficial microbes, these innovative treatments offer new hope for conditions that resist conventional drugs, including metabolic disorders and antimicrobial-resist... infections. As the demand for safer, more effective alternatives grows, understanding this field becomes increasingly vital. The upcoming book, Live Biotherapeutics: Advancing Microbial Medicine, will provide a comprehensive and accessible overview of the science, applications, and future potential of live biotherapeutics in transforming healthcare.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 51
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 51 provides comprehensive profiles of four pharmaceutical compounds: Vortioxetine, Rosuvastatin Calcium, Perindopril, and Ferulic Acid. In addition, it includes a review article concerning Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases. Chapters in this new release include Vortioxetine: A Comprehensive Profile, Rosuvastatin Calcium: A Comprehensive Profile, Ferulic Acid: A Comprehensive Profile, Perindopril: A Comprehensive Profile, Drugs and Polymer Based Local Delivery Systems in the Treatment of Periodontal Diseases, Kinetic Exclusion Assay Technology: Theory, Experimental Aspects, and Applications in Concentration Measurements Across Diverse Fields, and more.No other book series provides this essential information as promptly and pertinently. Sections provide review articles and database compilations categorized into five primary domains: Physical Profiles of Drug Substances and Excipients; Analytical Profiles of Drug Substances and Excipients; ADME Profiles of Drug Substances and Excipients; Methodology Pertaining to the Characterization of Drug Substances and Excipients; and Methods of Chemical Synthesis.

  • ATP

    From Neurotransmission to Cancer Therapy
    • 1st Edition
    • Ronald Sluyter + 5 more
    • English
    ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the “Molecular Mediators in Health and Disease” series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond.

  • Immuno-oncology and Immunotherapy Part G

    • 1st Edition
    • Volume 202
    • English
    Immuno-oncology and Immunotherapy, Part G, Volume 202 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including In situ imaging of pulmonary invariant Natural Killer T cells in precision cut lung slices, Immunofluorescent microscopy to quantify and characterize chromosomal instability, Spatial techniques for understanding the tumor microenvironment, Very high-flex immunophenotyping using co-linear cytofluorometric evaluation, Large-scale CRISPR-Cas9 screens to define regulators of immune checkpoint biology, Assessment of cytoplasmic dsDNA for cellular immunogenicty, and much more.Additional sections cover Harmonization of a multiparametric flow cytometry panel for immunological monitoring on PBMC and whole blood samples: a real-life example, Quantitative assessment of arterial remodeling from confocal microscopy image analysis of the mid-gestation mouse decidua, Phenotypic characterization and function of tumor infiltrating and peripheral B cells in cancer patients, Methodological Advances to analyze Cancer-Associated Fibroblast-derived ECM effects on Macrophage Polarization, and many other topics that will be of interest to readers.

  • Design and Applications of Cell-Free Systems Part B

    • 1st Edition
    • Volume 219
    • English
    Design and Applications of Cell-Free Systems, Part B, Volume 219 offers the latest information on cell free systems for the expression of transmembrane proteins, enzymes, proteins, therapeutics, vaccines, and uses in the biotransformation, translational modification, self-assembly of nano-biomaterials, and in synthetic biology design, challenges, and opportunities. It will help students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners understand cell-free systems and their applications in many areas. The book represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE).CFS requires core molecular machinery, including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins.

  • Simulating Protein Folding in Variable Environmental Conditions

    Transformation from Globular Proteins to Amyloids
    • 1st Edition
    • Irena Roterman-Konieczna
    • English
    Simulating Protein Folding in Variable Environmental Conditions: Transformation from Globular Proteins to Amyloids delves into the effects of external conditions upon the protein folding process. The book considers how this can lead to amyloid formation and why proteins fold the way they do. It presents the fuzzy oil drop model (FOD-M), which enables the measurements of external factors influencing the folding process and considers changed external conditions as the source for the misfolding process. Sections provide an introduction to amyloid transformation and outline the hypothesis of the model simulation before considering the role of environmental factors, including the water environment and membrane environment. This book is a useful resource for researchers interested in investigating protein folding across molecular biology, structural biology, biochemistry, computational biology and related fields.

  • Proteomics: A Promising Approach for Cancer Research

    Proteome Signaling Dysregulation in Cancer, Therapeutic Interventions, and Future Perspectives, Volume 2
    • 1st Edition
    • Muneeb U Rehman + 3 more
    • English
    Proteomics: A Promising Approach for Cancer Research Volume 2 Proteome signaling dysregulation in cancer, therapeutic interventions, and future perspectives provides an updated overview of scientific knowledge, achievements, and findings in the field of cancer proteomics. The field of cancer proteomics is very dynamic, with emerging trends specifically related to clinical solutions. The book content was developed to help readers get up to speed on the topic and easily apply learnings into research or clinical practice.Volume 2 covers proteome signaling, their dysregulation to therapeutics options and future prospects in 17 different signaling pathways. It capitalizes the enormous interest in proteomics among academics and gives new viewpoints on this topic in cancer treatment. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment.

  • Genetic Regulation of Immune Response Pathways

    • 1st Edition
    • Volume 115
    • English
    Genetic Regulation of Immune Response Pathways, Volume 115 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Chapters explore the genetic regulation of immune cells upon activation, IFN response regulation during viral infections, and the role of noncoding RNAs—including lncRNAs and ncRNAs—in immune regulation and inflammation. Additional sections examine the JAK-STAT signaling pathway in inflammatory and autoimmune diseases as a potential therapeutic target, long noncoding RNAs as key regulators of autoimmunity, and the importance of appropriate cytokine expression in maintaining immune response homeostasis.Together... these contributions provide valuable insights into the molecular and genetic mechanisms underlying immune-mediated processes.

  • Antimicrobial Peptides and Proteins

    • 1st Edition
    • Volume 149
    • English
    Antimicrobial Peptides and Proteins, Volume 149 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Nature and mechanistic action of Antimicrobial Peptides, Advances in elucidation molecular targets and mechanisms of action of AMPs: beyond membrane disruption, Discovery, Design, and Applications of Antimicrobial Peptides, Designing Potent Antimicrobial Peptides Against Acinetobacter baumannii: A Combined Approach Using Genetic Algorithms and Machine Learning Strategies, Protection of Diabetic Wound Patients from Invasive Bacterial Infections by Innate Antimicrobial Peptides, and more.Additional chapters explore Bacteriophage Lysins as a potential therapeutic strategy for Methicillin Resistant Staphylococcus aureus infections, Structural insights and therapeutic potential of host defense peptides in combatting antimicrobial resistance, Antimicrobial protein as a cargo for antimicrobial nanomaterials to combat Gram-negative bacteria, Unravelling the Role of Antimicrobial Proteins in Leptospirosis: A Comprehensive Transcriptomic Analysis, and Deciphering Antimicrobial Peptide (AMP) Resistance Mechanisms in Enterococcus faecalis Through Integrated RNA-Seq and Hub Genes Identification.

  • Design and Applications of Cell-Free Systems Part A

    • 1st Edition
    • Volume 218
    • English
    Design and applications of cell-free systems –Part A represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE). CFS requires a core molecular machinery including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins. It has the potential to overcome loopholes in the current in vivo production systems and it is promising tool in both basic and applied scientific research. It facilitates a simplified organization of desired experiments with a variety of reaction conditions, making CFS a powerful tool in biological and translational science research.This volume offers wide range of topics on different aspects of cell free systems design and their applications. It covers introduction to applications of cell-free systems, protocol for cell free design, transcription and translation, computational biology, artificial intelligence, automation and robotics for cell free systems, cell free for biosensor, low cost diagnostics, cell free based high throughput screening, biodesign and incorporation of non-natural amino acids into proteins. This volume helps students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand cell-free systems and their applications in many areas.

  • Immuno-oncology and Immunotherapy Part F

    • 1st Edition
    • Volume 201
    • English
    Immuno-oncology and immunotherapy, Part F, Volume 201 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including an Evaluation of agents that affect anti-tumor function of CD8+ T cells at activation, Cancer cyro-immunotherapy: Models and methods, Methods for analysis of cancer- and TLS-associated immune infiltrates by multiplex immunofluorescence histology, In-vivo measurement of the extracellular ATP concentration by bio-luminescent probes, and much more.Additional sections cover the Analysis of the tumor microenvironment using imaging mass cytometry data, Saphenous vein blood collection for different immune analyses of living mice, Use of mouse KO models to validate the specificity of monoclonal antibodies, Imaging mass cytometry to analyze the immune TME, Autoimmune arthritis: Transgenic mouse models and methods, Assessment of human and mouse tumor-antigen specific CD8+ T cells by multimer staining in multiple compartments, and more.

  • Molecular Biology Techniques

    A Classroom Laboratory Manual
    • 5th Edition
    • Sue Carson + 3 more
    • English
    Molecular Biology Techniques: A Classroom Laboratory Manual, Fifth Edition, is an in-depth laboratory manual for upper-level undergraduates and beginning graduate students in the general field of molecular biology techniques and biochemical applications. Presented as a series of coordinated experiments that mimics either a one- or two-semester research experience, the book also provides theories and explanations behind the techniques. Topics include manipulation of recombinant DNA, protein expression and purification, analysis of mRNA levels, mammalian cell culture techniques, CRISPR-mediated gene knockdown, and more. New topics, such as Gibson assembly experiments, have also been included. For instructors, the book contains easy to follow guides and preparation lists, designed to facilitate lab setup and pre-lab questions for use as a teaching tool.

  • Cell Physiology Sourcebook

    • 5th Edition
    • F. Javier Alvarez-Leefmans + 1 more
    • English
    Written by leading experts in the field, the fifth edition of the Cell Physiology Sourcebook, Fifth Edition offers a critical, comprehensive, and multidisciplinary overview of essential aspects of cell physiology and biophysics, spanning from bacterial and archaeal cells to mammalian cells and tissues. The present edition incorporates new molecular insights without losing the integrative perspective of cell physiology and biophysics, as well as its foundational concepts. Our target readers are advanced students and researchers interested in understanding how cells work.The history of this book goes back to Hugh Davson’s classic A Textbook of General Physiology, which reached its fourth and last edition in 1970. The successor of this influential work was Cell Physiology Sourcebook, first published in 1995 and edited by the late Professor Nicholas Sperelakis, with a foreword written by Davson. At that time, the knowledge of molecular and cell physiology became so vast that a single author's work, like its predecessor, was materially impossible. Professor Sperelakis, for whom we dedicate the present edition, put together an impressive volume with the contribution of various experts in fundamental areas of the field until the 4th edition, published in 2012, one year before his death. This book's success and the gap it fills motivated the present editors to continue this project, updating the entire book to reflect new developments.

  • RNA Enzymology and Technology

    • 1st Edition
    • Volume 725
    • English
    RNA Enzymology and Technology, Volume 725 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as RNA enzymes in transcription, RNA processing, translation regulation, RNA transcriptase in gene expression regulation, Enzymes Involved in Ribosome Biogenesis and Translation Regulation, In Vitro Transcriptase: Methods for Studying RNA Synthesis, RNA Enzymes in RNA Silencing and Regulation, RNA Silencing Machinery: Mechanisms of RISC and MicroRNA Regulation, Enzymes in RNA-Based Therapeutics, and much more.Other chapters cover Antisense Oligonucleotides (ASOs) and RNase H: Mechanisms and Applications, RNA Enzymes in Targeted Therapeutics: From Bench to Bedside, Enzymes in RNA Sequencing and Analysis, Enzymes in High-Throughput RNA Sequencing: Applications and Challenges, Advanced Techniques and Future Directions, and much more.

  • DNA in Health, Identity, and Ancestry

    • 1st Edition
    • Hisham Atan Edinur + 2 more
    • English
    DNA in Health, Identity and Ancestry examines the human genome and advances in molecular techniques in relation to their value in health, genetic ancestry, and forensic DNA. This book systematically presents these three areas, providing new insights into recent developments in these fields, including gene editing, ancestral fraction determination, and DNA profiling. It covers the latest advances in molecular biology to understand the pertinent issues in these areas. DNA in Health, Identity and Ancestry provides an introduction to human genomes, and then delves into health, forensics and ancestry across 36 chapters. Each section is concluded with practical case studies to demonstrate the application of the principles discussed in each respective section. This book is a valuable resource for researchers, practitioners, and postgraduate students in biochemistry, molecular biology and genetics. It not only provides them with fundamental knowledge on genetics, diseases, population genetics and forensic DNA, but also presents advances, technical operational standards, analytical tools and recent developments in these respective areas.

  • Frontiers of Cancer Biology

    Current Trends in Cancer Research
    • 1st Edition
    • Devavarapu Kasi Viswa Prasad + 1 more
    • English
    Frontiers of Cancer Biology: Current Trends in Cancer Research presents the latest research in cancer, which is advancing day by day. This book provides an introduction to cancer genetics, as well as the roles of genomic instability, oncogenes, proto-oncogenes, tumor suppressor genes, and DNA damage and repair in relation to cancer. It then goes on to discuss viral genomics and cancer, epigenetics and cancer, cancer genetics, gene therapy in precision medicine. Finally, this book reviews the future direction of cancer genetics. Frontiers of Cancer Biology: Current Trends in Cancer Research is a valuable resource for researchers and professionals working in cancer biology, as well as academics that want to keep up to date with the field.

  • Proteomics in Cell Communication

    • 1st Edition
    • Volume 200
    • English
    Proteomics in Cell Communication, offers a comprehensive exploration of the dynamic field of proteomics and its vital role in understanding cellular communication. This book includes interesting chapters on topics such as In vivo cell-type specific secretome profiling, Assays for surface antigens in extracellular vesicles using proximity labeling strategy, Cell type-specific proximity biotinylation using TurboID to identify secreted proteins from cardiomyocytes in vitro and in vivo, Native-state and cell type-specific proteomics using TurboID proximity labeling in mouse models, Adapted Luminex approach to assess phosphoproteins and cytokines released from specific cell types in the brain in vivo, and much more.Other sections covers In-depth cell-selective proteomics and secretomics in vivo based on azidonorleucine labelling, Visualizing and profiling de novo protein synthesis in Drosophila with cell-type specificity, A Split GFP Approach for Cell-Type-Specific Protein Localization Analysis in Drosophila, Quantitative deep profiling of the cell surface proteome using the "Cell Surface Capture" technique, Proteomic profiling of extracellular fluids to identify secreted proteins from muscle and fat tissues, and much more.

  • Methods for the Study of Microbial Biofilms

    Current Trends and Recent Advancements
    • 1st Edition
    • Abhishek Guldhe + 2 more
    • English
    Methods for the study of microbial biofilms: Current Trends and Recent Advancements provides a detailed overview of the latest techniques for the study of biofilms. The book explores a wide range of methods for the characterization and study of cells within biofilms, including microscopy techniques, genomic approaches, transcriptomics, proteomic and proteogenomic tools. Computational and mathematical modelling are also covered.Chapters investigate the physiology of biofilm cells, gene expression pathways related to the formation, maturation and dispersion of biofilms, and molecular factors governing the biofilm formation and development, providing an overview of techniques that can be used at the cellular and molecular level. This book provides a broad overview of the biofilm field, along with the range of techniques that can be used to study and better understand them.

  • Protein Misfolding Diseases

    • 1st Edition
    • Volume 148
    • English
    Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores interesting and updated topics, including Protein misfolding in hemophilia, Characterizing Protein Misfolding: Inside and Out, Heat Shock proteins (HSPs) as chaperones for Oncogenesis, Protein Misfolding and Cancer: Molecular Insights and Future Perspectives, Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders, Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook, and much more.Additional sections cover Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases and Calpain- mediated proteolytic cleavage.

  • Harnessing Genomic Tools for Crop Improvement

    A Software User Manual for Transforming Geneticists to Genomicists
    • 1st Edition
    • Lakshmi Narayana R. Vemireddy + 2 more
    • English
    In the rapidly evolving landscape of crop genetics, the book, Harnessing Genomic Tools for Crop Improvement is an essential resource designed for researchers, students, and professionals seeking to leverage bioinformatics tools for precision breeding. This comprehensive manual provides step-by-step guidance on utilizing molecular data derived from genetics and breeding experiments, offering hands-on instructions for key software applications in genetic diversity analysis, QTL mapping, genome-wide association mapping, haplotype analysis and genomic selection.Beyond technical tutorials, the book explores cutting-edge bioinformatics tools such as sequence databases, BLAST, primer designing, and sequence alignment, ensuring users gain a holistic understanding of genomics-driven crop improvement. Definitions, terminology clarifications, and interpretation of the results help bridge the gap between theory and application, simplifying complex analyses.Whether you are a novice or an experienced researcher, this book equips you with the skills to analyze and apply genomic data effectively, making it an invaluable asset for transforming geneticists into genomicists in both plant and animal sciences.

  • Nanomedicine and Nutrigenomics

    Pioneering the Future of Health
    • 1st Edition
    • Yugal Kishore Mohanta + 2 more
    • English
    Nanomedicine and Nutrigenomics: Pioneering the Future of Health offers a comprehensive introduction to nanomedicine and nutrigenomics, ensuring readers grasp the fundamental concepts, techniques, and applications. The book provides an overview of nanotechnology, nanomaterials, and gene-nutrient interactions, paving the way for understanding the potential healthcare applications of these groundbreaking methodologies. It emphasizes the synergy between nanomedicine and nutrigenomics, showcasing how they can optimize health outcomes and delving into nanotechnology's role in enhancing drug delivery systems, diagnostics, and therapeutics, while also highlighting personalized nutrition interventions based on genetic makeup. The book addresses future advancements, ethical implications, and challenges, presenting a holistic view.

  • Genome Chaos

    Rethinking Genetics, Evolution, and Molecular Medicine
    • 2nd Edition
    • Henry H. Heng
    • English
    Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine, Second Edition transports readers from Mendelian genetics to 4D genomics, building a case for genes and genomes as distinct biological entities where the genome, rather than individual genes, defines system-level inheritance and represents a clear unit of selection for macroevolution. In this thought-provoking text, Dr. Henry Heng invigorates fresh discussions in Genome Architecture Theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine.In this timely new edition, Dr. Heng fully embraces the integration of system information with genome-mediated evolutionary mechanisms, and supports this framework with recent findings and growing, interdisciplinary research. Ten evidence-based chapters discuss 4D genomics, genes and genomes as distinct biological entities, genome chaos and cellular macroevolution, karyotype coding and fuzzy inheritance, as well as an entirely novel model of evolution driven by information flow, and more. Brand-new chapters consider the creation and maintenance of system information for complexity and biodiversity, as well as modes of analyzing information-based and historically contingent evolutionary framework. This synthesis offers a revolutionary paradigm of evolutionary theory. It also hypothesizes about how information flow, matter arrangement, and energy interact.

  • Biology of Fatty Acids

    Biochemical, Nutritional and Pharmacological Functions
    • 1st Edition
    • E. P. Meran Keshawa + 1 more
    • English
    Biology of Fatty Acids: Biochemical, Nutritional, and Pharmacological Functions offers an in-depth exploration of the vital roles fatty acids play in human health. From their influence on metabolism and immune functions to their potential in disease prevention and treatment, this book covers a wide range of topics. With contributions from leading experts, it examines the latest research on fatty acids in nutrition, emerging plant-based sources, and their pharmacological potential in treating conditions like neurodegenerative diseases and cancer. A must-read for scientists, healthcare professionals, and anyone interested in the transformative impact of fatty acids on human health.

  • Bacterial Efflux Systems

    • 1st Edition
    • Volume 724
    • English
    Bacterial Efflux Systems, Volume 722 covers experimental and computational approaches to study the function, structure, and mechanism of bacterial efflux pump systems. The methods covered include preparation of samples for structural and functional analyses and in vivo activity analysis. Specific chapters in this release cover Efflux pump functional assays, NMR and functional analysis efflux pumps, Methods for saturation mutagenesis and functional characterization, Cooperation and functional interplay between pumps, Mapping interactions, HDX-MS, and much more.Other sections cover Recombinant Expression and purification, Reconstitution of a RND efflux pump in different artificial membranes for a structural biology approach, Reconstitution of rnd and mfs efflux pumps for structural biology, CusCBA system, Expression and purification of efflux pumps of Gram positives, Expression and purification of efflux pumps of archaea, ABC transporters: BmrA preparation for NMR and PatA/PatB in peptidisc, In situ structural analysis of efflux assemblies by cryoET, Molecular dynamics simulations, and so much more.

  • Cyclic Peptides

    • 1st Edition
    • Volume 723
    • English
    Cyclic Peptides, Volume 721 covers peptide structures and their enhancement, stability, specificity, and overall functionality. As a growing suite of computational and experimental tools support the discovery and optimization of these molecules, ranging from well-established modeling platforms to emerging deep-learning algorithms that expand design possibilities, this book aims to provide a comprehensive overview of cyclic peptide research, covering fundamental principles, production strategies, and the latest technological advances in both synthetic and computational realms.Cyclic peptides are a powerful approach to constraining peptide structures, enhancing their stability, specificity, and overall functionality. They can be generated through diverse techniques—including chemical synthesis, mRNA display, and DNA display—that enable the creation of tailored peptide libraries.

  • The Future of Human Evolution

    • 1st Edition
    • Rene J. Herrera + 1 more
    • English
    The Future of Human Evolution provides a discussion of how cultural, biological and microevolutionary (drift, selection, and mutation) pressures might affect our future as a species. The book is split into twelve chapters, beginning with evolutionary forecasting, and gene and culture coevolution. It then discusses life expectancy and population growth, followed by chapters on mutation rates, climate change and diet. This book also explores artificial selection and ‘designer babies’, trans-humanism and artificial intelligence (machine-human symbiosis), inequality and the colonization of space. The Future of Human Evolution serves as a valuable resource for both researchers and students studying human evolution and human population genetics, as well as non-academics with an interest in human evolution.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 168
    • English
    Advances in Cancer Research, Volume 168 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Plasticity in cell adhesion during cancer progression, AEG-1 on Cancer Drug Resistance: From Molecular Insights to Therapeutic Challenges, Multimodal AI to differentiate tumor progression from treatment effect in glioblastoma, The Role of Epigenetic Modifications in Mediating Cancer Health Disparities, In search of a targetable immune profile for acute myeloid leukemia, Notch signaling in tumorigenesis and maintenance of cancer stem cells, and much more.

  • Extracellular Vesicles: Advances and Perspectives in Treatments, Therapies, and Vaccination

    • 1st Edition
    • Volume 96
    • English
    Extracellular Vesicles: Advances and Perspectives in Treatments, Therapies, and Vaccination, Volume 96 explores the field of extracellular vesicles (EVs) and their potential applications in treatments, therapies, and vaccination. Covering a broad range of topics from EV-based biomarker detection to vaccine development and theranostic applications, this new release in the series includes chapters on Extracellular Vesicles: Advances in Treatments, Therapies, and Vaccination, Extracellular Vesicles: Advances in Therapies and Vaccination in virus, Products of excretion-secretion and extracellular vesicles derived from zoonotic helminths: a two-face response, and more.Additional sections cover Extracellular Vesicles in Fungal Pathogenesis: Mechanisms and Implications, Extracellular vesicle-based vaccines: a promising approach for parasitic diseases, Extracellular Vesicles as Vaccines Against Infectious Diseases, EVs and images, Bacterial Outer Membrane Vesicles: Potential and Applications in Next-Generation Vaccines, Theranostic application of extracellular vesicles in breast cancer, and much more.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 102
    • English
    Advances in Marine Biology, Volume 102 in the Advances in Marine Biology series, the latest release in this long-standing serial, presents cutting-edge developments in marine biology with a focus on diverse themes influencing ocean ecosystems. This volume features chapters on highly informative topics such as The Inclusion of habitat quality into fisheries models, The urgent need to better define, quantify and identify the drivers of "water quality" on tropical coral reefs (opinion article), Indigenous knowledge and marine systems, and Sensory perception in marine larvae.

  • Biochemical and Molecular Mechanisms of Secondary Metabolites in Metabolic Diseases

    • 1st Edition
    • Kanwal Rehman + 1 more
    • English
    Biochemical and Molecular Mechanisms of Secondary Metabolites in Metabolic Diseases explores the therapeutic potential and pharmacological roles of secondary metabolites (SMs) in managing metabolic disorders. This comprehensive volume provides a detailed examination of the biochemical pathways, molecular mechanisms, and pharmacodynamics of SMs, offering insights into their potential as future drug candidates for metabolic diseases. The book begins by explaining the differences between secondary and primary metabolites, providing clear classification and organization of SMs. It highlights recent research on SMs, including receptor interactions and molecular signal transduction pathways, to showcase their potential as interventions against metabolic disorders.The role and mechanistic details of SMs at the molecular level are illustrated, emphasizing their pharmacological participation in treating conditions such as obesity, diabetes, cardiovascular diseases, and inflammation. This book is an essential resource for students and professionals in pharmacy, medical subjects, nursing, herbal medicine, and traditional medicine programs, aligning with curricula in medical ethnobotany, ethnopharmacology, pharmacognosy, phytochemistry, and related fields. It also serves as a valuable reference for researchers in pharmacology, biochemistry, and medicinal chemistry, as well as clinicians interested in natural product-based therapeutics for managing metabolic conditions.

  • Genome Analysis

    Principles and Methods
    • 1st Edition
    • Dev Bukhsh Singh + 1 more
    • English
    Genome Analysis: Principles and Methods provides recent and advanced information about genome analysis approaches and techniques to study and annotate the structure and function of the genome. It is a compendium of important topics such as NGS analysis, genome fragmentation and assembly, metagenomics, cloning and expression, physical marker analysis, transcriptome data analysis, sequence alignment and comparison, evolutionary analysis, SNP analysis, genome-based disease diagnosis and therapies, micro-RNAs, pharmacogenomics, genetic approaches to disease intervention, and challenges with opportunities in genome analysis and genomics, etc.The latest developments in the field are discussed, and key concepts are introduced to ensure readers understand advanced concepts and methodologies in the area. The book serves as a valuable guide to the present, emerging, and evolving research methodologies in the field.

  • Transketolases

    • 1st Edition
    • Volume 722
    • English
    Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented.

  • Advances in Management of Pediatric Brain Tumors

    • 1st Edition
    • Volume 167
    • English
    Advances in Management of Pediatric Brain Tumors, Volume 167 encapsulates the latest developments in the field for various types of pediatric brain tumors. By examining these survival gaps, the volume offers insights into strategies for improving outcomes and bridging the gap in care on a global scale. Chapters in this new release include Pediatric-type diffuse low grade gliomak, Pediatric-type diffuse high grade glioma/Diffuse Midline glioma, Ependymoma, Choroid plexus tumors, Embryonal tumors/medulloblasto... Craniopharyngioma and other sellar-region tumors, and much more.Other sections cover Germ cell tumors, Immunotherapy for pediatric brain tumors, Emerging interventional treatments in the management of pediatric brain tumors, and Management of pediatric brain tumors in low-middle income countries.

  • γδ T Cells in Health and Disease Part B

    • 1st Edition
    • Volume 398
    • English
    γδ T Cells in Health and Disease, Part B provides a comprehensive and up-to-date overview of the diverse roles that γδ T cells play in human physiology and pathology. This volume builds on foundational knowledge to explore advanced topics and recent discoveries in γδ T cell biology, with a particular focus on their mechanisms of action, functional diversity, and implications for clinical practice. Chapters in this new release cover Development of gd T cells, Human T-cell receptor inborn errors of immunity shed light on the real-life role of γδ vs αβ T lymphocytes, and much more.Other sections explore Deciphering the Role of γδ T cells in Skin Inflammatory Diseases: Insights from Psoriasis, Atopic Dermatitis, and Alopecia Areata, Role of gd T cells in zoonosis infection, γδ T cells in Escherichia coli infection and Gamma-delta T cells in breast cancer: dual role in tumor immunity and emerging therapeutic approaches.

Related subjects