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Elsevier

Books in Life sciences general

Providing a broad overview of biological systems, ecology, evolution, and molecular biology, this selection supports researchers, educators, and students across life sciences. It features foundational concepts, recent advances, and interdisciplinary approaches that promote comprehensive understanding and innovative research in the biological sciences.

  • The Potential of Intermittent Fasting in Age-related Diseases and Precision Anti-aging Therapeutics

    • 1st Edition
    • Abhishek Kumar Singh + 2 more
    • English
    The Potential of Intermittent Fasting in Age-related Diseases and Precision Anti-aging Therapeutics takes an in-depth look at the beneficial and efficacious role of Intermittent Fasting (IF) in a wide array of aging-associated diseases. It provides a comprehensive resource that not only outlines the potential benefits and future research directions but also delves into the limitations and nuances of IF in managing these conditions. The book is divided sections and begins by covering the fundamentals of aging and the effects of IF. Subsequent sections examine the physiological impact IF has on aging; its potential influence on stress resistance, heart, gut, and overall health optimization; social and ethical considerations as a therapeutic strategy; bridging IF research findings and clinical practice; and the potential integration and application of IF into age-related diseases treatment. Offering a consolidated and scientifically grounded perspective aimed at equipping readers with a balanced understanding, this book serves as a go-to reference for researchers and clinicians alike seeking clear and accurate insights into how IF can positively influence the health and longevity of the aging population.

  • Basics in Amino Acid Metabolism in Humans in Health and Disease

    • 1st Edition
    • Milan Holeček
    • English
    Basics in Amino Acid Metabolism in Humans in Health and Disease summarizes the significance of amino acids and their metabolism. This book provides a single source of information bringing together a wide variety of research on the subject, explaining the rationality and risks of using some amino acids as dietary supplements. The first chapters describe amino acids' structure, classification, and transport across cell membranes and their role in protein synthesis, gluconeogenesis, and ketogenesis. The central part of the book is focused on the role of individual amino acids in the synthesis of various biologically essential substances and their metabolism in acquired and hereditary diseases. The following chapters are dedicated to the role of particular organs, such as the small intestine, intestinal microbiota, liver, muscle, kidneys, brain, adipose tissue, and lungs. The next sections are focused on amino acid metabolism under various physiological (food intake, starvation, exercise, and elderly) and pathological (systemic inflammatory response, cirrhosis, diabetes, chronic renal insufficiency, and cancer) conditions. The last chapter summarizes the benefits and potential adverse effects of increased intake of individual amino acids. The author, Professor Milan Holeček, has been studying and researching in the area for over 40+ years. "Basics in Amino Acid Metabolism in Humans in Health and Disease" is written for healthcare professionals, primarily nutritionists, specialists in intensive metabolic care, clinical nutrition, diabetology, hepatology, gerontology, gastroenterology, nephrology, and oncology.

  • Endothelium and Cardiovascular Diseases

    Vascular Biology and Clinical Syndromes
    • 2nd Edition
    • Protasio L. Da Luz + 3 more
    • English
    Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia... diabetes, and hypertension are discussed at length.With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health.

  • An Introduction to Applied Clinical Ethics in Pathology and Laboratory Medicine

    A Case-Based Approach
    • 1st Edition
    • Ifeoma U. Perkins
    • English
    An Introduction to Applied Clinical Ethics in Pathology and Laboratory Medicine: A Case-Based Approach offers an organized pragmatic approach to processing ethical dilemmas that frequently occur in pathology and laboratory medicine in a systematic way. This is a novel resource strategically crafted in a case-based format to help readers confidently reach potential solutions with strong ethical reasoning that not only further quality patient care but honor the good intentions of pathologists and laboratorians. Readers will gain confidence in their ability to think critically about complex problems in pathology that create ethical conflict. This book is for healthcare providers, practicing anatomic and clinical pathologists, pathology residents and fellows, pathology educators and graduate medical education program directors, students of allied health sciences, researchers, laboratory technologists, and any members of the clinical care team who utilize laboratory services.

  • Medications for Older Persons

    Recommendations, Harms, Evidence
    • 1st Edition
    • Roger Thomas
    • English
    Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons’ alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention.

  • Preventable Medical Errors

    The Role of Different Sciences in Medical Education and Practice
    • 1st Edition
    • Erwin B. Montgomery Jr.
    • English
    Preventable Medical Errors: The Role of Different Sciences in Medical Education and Practice addresses the issues of staying up to date with evolving medical practices, by providing practical examples linked to real-world patient safety concerns and illustrating theoretical discussions with clear clinical practice scenarios. The book is divided into two sections, Part 1 - How Did It Come To This? and Part 2 - Where Does It Go From Here?; which guide the reader through how we got here historically and how we can navigate our way out using the tools the author presents. Thus paving the way, bridging a gap between theory and practice, while emphasizing the importance of patient safety. Written for all medical professionals, at the forefront of postmodern and scientific medical advancements, to ultimately improve clinical outcomes and reduce preventable medical errors.

  • Liquid biopsy in Cancer Management

    Integrating Diagnostics and Clinical Applications
    • 1st Edition
    • Shvetank Bhatt + 3 more
    • English
    Liquid biopsy in Cancer Management: Integrating Diagnostics and Clinical Applications provides a comprehensive overview of liquid biopsy, covering its fundamental principles, technological advancements, clinical applications, and future prospects. In 16 chapters, the book focuses both on the practical implications of liquid biopsy in cancer management, and on its role in early detection, treatment monitoring, and personalized therapy. It emphasizes the integration of liquid biopsy into both diagnostic practices and therapeutic strategies, highlighting its potential to transform cancer care. The book discusses the latest research findings and explores future directions in liquid biopsy research, providing readers with a forward-looking view of the field.It includes case studies and examples to illustrate the clinical utility of liquid biopsy and enhance understanding of its applications. Overall, the book aims to be a comprehensive and authoritative resource on the subject, providing readers with a thorough understanding of the current state and future directions of liquid biopsy in cancer management.

  • Sleep and Health

    • 2nd Edition
    • Michael A. Grandner
    • English
    Sleep and Health, Second Edition provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community, and population levels, along with a discussion of the implications for public health, public policy, and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more.

  • Pathology of the Laboratory Rabbit

    • 1st Edition
    • Alys Bradley
    • English
    Pathology of the Laboratory Rabbit serves as a “go to” text for all pathologists working on laboratory rabbits in safety assessment studies. The book helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these animals which are also kept as domestic pets. The book provides a comprehensive text on the spontaneous pathology seen in common laboratory rabbit strains. This is the first book collating information on all organ systems in these strains.

  • Translational Neurosurgery

    • 1st Edition
    • Adam E.M. Eltorai + 2 more
    • English
    Translational Neurosurgery provides a comprehensive overview reflecting the depth and breadth of the field of translational research focused on neurosurgery, with input from a distinguished team of basic and clinical investigators. It covers the principles of evidence-based medicine and applies these principles to the design of translational investigations, helping researchers navigate challenging considerations in study design and implementation. This book is a valuable resource for neurosurgeons and neurosurgery investigators who want to understand more about translational research, and also for basic scientists interested in translating their research into clinical practice.

  • Nanocarriers in Prostate Cancer

    Advanced Diagnosis and Treatment Strategies
    • 1st Edition
    • Bhupendra G. Prajapati + 3 more
    • English
    Nanocarriers in Prostate Cancer: Advanced Diagnosis and Treatment Strategies provides a comprehensive, up-to-date resource on the latest advancements in nanotechnology for prostate cancer therapy. Sections delve into different types of nanomaterials, including polymeric nanoparticles, DNA origami nanocarriers, and dendrimers. Each chapter explores their unique applications in targeted drug delivery, imaging, and therapeutic strategies, providing detailed insights into how nanotechnology revolutionizes prostate cancer care. This book benefits researchers, clinicians, and students focused on oncology and nanomedicine by offering a deep dive into the potential of nanocarriers in prostate cancer treatment.This book bridges the gap between cutting-edge research and clinical applications, offering insights into how various nanocarriers enhance drug delivery, improve imaging techniques, and provide targeted, less invasive treatments. It serves as a valuable resource for developing more effective, personalized treatments, leading to improved patient outcomes and reduced toxicity associated with traditional therapies.

  • Electrocardiographic Left Ventricular Hypertrophy

    Looking Beyond Left Ventricular Mass
    • 1st Edition
    • Ljuba Bachárová + 1 more
    • English
    Electrocardiographic Left Ventricular Hypertrophy: Looking Beyond Left Ventricular Mass provides an innovative perspective on electrocardiograms (ECGs) usage for evaluation of left ventricular hypertrophy (LVH). It links contemporary research results with clinical practice in order to advance application of this cornerstone technology. Specifically, it highlights how standard ECGs can provide unique information on the cardiac electric field in LVH patients.This book recognizes and fulfills the urgent need to change the classical diagnostic paradigms of ECG diagnosis in LVH. To do so, it turns attention to so-called false-negative ECG findings that in truth provide valuable information that largely overlooked. When used to their fullest potential, these results can be used for enhanced diagnosis, selection of targeted therapy and cardiovascular risk assessment.

  • Viral Proteases

    • 1st Edition
    • Volume 58
    • English
    Viral Proteases, Volume 58 in The Enzymes series, presents a comprehensive overview of recent advances in the structural and functional understanding of viral proteases and their potential as drug targets. This new volume includes chapters covering a wide range of topics, including Viral proteases as targets for antiviral drugs, Structural biology of viral proteases, Computational approaches for designing viral protease inhibitors, The peptidomimetic approach for the design of viral protease inhibitors, HIV protease and its inhibition, and much more.Additional sections cover Hepatitis C virus (HCV) proteases: structure, function and inhibition strategies, Coronaviruses main proteases and their inhibitors, Coronaviruses papain-like proteases, Flaviviruses proteases (Zika, West Nile, Dengue), Bacteriophage endolysins, and Challenges for developing selective viral protease inhibitors as anti-infectives.

  • Artificial Intelligence in Patient Counselling

    • 1st Edition
    • Bhupendra G. Prajapati + 3 more
    • English
    Artificial Intelligence in Patient Counselling explores the transformative role of artificial intelligence in enhancing patient counseling and education. The book delves into how cutting-edge AI technology is reshaping the healthcare landscape, improving patient experiences, and driving better health outcomes. It provides a comprehensive overview of the ways AI can address the challenges of personalized and effective patient care. Sections cover a wide range of topics, including the creation of personalized treatment plans through AI's analysis of patient data, the emergence of AI-powered virtual health assistants for 24/7 support, and the use of predictive analytics to identify early disease progression. Additionally, it explores AI-enhanced medical imaging, empathetic AI chatbots, ethical considerations, and real-world case studies that illustrate the tangible benefits of AI in patient counseling and education. By offering insights from leading experts, it empowers readers to navigate the evolving healthcare landscape with confidence and compassion. The book provides essential knowledge and tools for improving patient outcomes and modernizing patient care through AI-driven solutions, making it a valuable resource for understanding the impact of AI on patient care and education.

  • Lateral Flow Assays

    From Bench to Market
    • 1st Edition
    • Sibel Ayşıl Özkan + 1 more
    • English
    Lateral Flow Assays: From Bench to Market provides a detailed understanding of lateral flow assays (LFAs), the technology behind them, and their potential uses. The book opens with a discussion of the key elements of LFAs before covering a range of different LFA types, including aptamer-based and SERS-based LFAs. Applications across the biosciences and beyond are explored, such as virus detection, including Covid-19, bacteria detection, hormonal detection, and cancer biomarkers. LFAs for the detection of narcotics, environmental pollutants, food additives, allergens, toxins, and metabolites are also explored. The book then discusses commercialization aspects of LFAs before looking to future developments.This book offers a complete overview of these biosensors and is an ideal reference for researchers and lab technicians across the biomedical sciences who work with these devices. It is also relevant to researchers and practitioners in food chemistry, the environmental industry, and pharmaceutical companies, in addition to those involved in the development of lateral flow devices.

  • Understanding Renal Biochemistry

    Insights from Nephrotic Syndrome to Systemic Renal Dynamics
    • 1st Edition
    • Emmanuel Kwaku Ofori + 1 more
    • English
    Understanding Renal Biochemistry: Insights from Nephrotic Syndrome to Systemic Renal Dynamics provides a comprehensive exploration of nephrotic syndrome and related renal disorders. Tailored for academicians, young researchers, and graduate/postgraduat... students worldwide in fields such as renal research, chemical pathology, medical biochemistry, pharmacology, laboratory science, and pathology, this book offers cutting-edge insights into novel diagnostic approaches, underlying pathophysiology, and effective management strategies. Enriched with real-world case studies, it bridges theoretical knowledge with practical application, empowering readers to advance their understanding and make informed decisions in the diagnosis and treatment of renal diseases. The book provides a well-structured exploration of renal biochemistry and related disciplines, guiding readers through foundational concepts to advanced research and future directions in nephrology. Authored by experts, chapters cover topics such as renal biomarkers, diagnostic precision, therapeutic interventions, and management strategies, with case studies illustrating real-world applications. Each chapter begins with a clear outline, incorporates strategic case studies, and concludes with comprehensive summaries, ensuring readers can easily grasp core concepts and benefit from practical insights, enhancing their learning experience and retention of knowledge. With each chapter supplemented by figures, tables, and case studies, this book provides a comprehensive resource for anyone seeking to deepen their understanding of renal pathophysiology and its clinical management. For scientists and researchers, the book fills a crucial gap by providing a comprehensive resource on renal pathophysiology, covering both glomerular and tubular dysfunctions, thus offering valuable insights and the latest advancements in nephrology research. For clinicians, it serves as an essential reference, offering extensive information on relevant biochemical markers for disease diagnosis, providing practical guidance to enhance clinical practice and improve patient outcomes.

  • Diabetes and Alzheimer's Disease

    Mechanisms and Management
    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Diabetes and Alzheimer's Disease: Mechanisms and Management delves into the complex relationship between diabetes and Alzheimer’s disease. The book examines how these conditions intersect and influence each other, providing insights into their pathophysiological and epidemiological aspects. Readers will gain a thorough understanding of metabolic interactions, molecular signaling, and various factors that regulate the confluence of these diseases. Written by experts, this comprehensive guide is essential for researchers, academicians, scientists, and graduate students in biomedical and pharmaceutical sciences. In addition to exploring the mechanisms, the book discusses theranostics and strategies to manage both conditions.It includes sections on drug repositioning, dietary modifications, and the impact of metabolic dysfunction on neurological disorders.

  • Bioinformatics, AI, and Machine Learning in Microbial Drug Development

    • 1st Edition
    • Vagish Dwibedi + 3 more
    • English
    Bioinformatics, AI, and Machine Learning in Microbial Drug Development provides a comprehensive framework for integrating diverse fields like microbiology, bioinformatics, artificial intelligence, and machine learning, allowing readers to navigate complex interdisciplinary challenges effectively. This title offers an in-depth exploration of how these technologies are seamlessly integrated into pharmaceutical microbiology. The book, divided into 4 parts and 19 chapters, provides cutting-edge insights, practical guidance, and case studies. It emphasizes the importance of staying current with technological advancements, understanding ethical and regulatory issues, and optimizing drug production, making it an invaluable resource for industry professionals.

  • Nano-Bio-Medicine for Gastrointestinal Diseases

    • 1st Edition
    • Vivek Chaturvedi + 3 more
    • English
    Nano-Bio-Medicine for Gastrointestinal Diseases explores the transformative potential of biomedicine in gastroenterology, from innovative drug delivery systems to nanoscale imaging techniques. The book's content offers a detailed analysis of emerging technologies that are revolutionizing the diagnosis, treatment, and management of gastrointestinal disorders. By addressing conditions like inflammatory bowel disease and gastrointestinal cancers, readers gain a holistic understanding of how biomedicine is reshaping the entire landscape of gastroenterology. With a focus on personalized medicine approaches and future perspectives, this book inspires collaboration and awareness among researchers, medical practitioners, and patients, ultimately leading to improved outcomes and quality of life. Sections cover a wide range of topics that are essential for understanding the intersection of biomedicine and gastroenterology. Beginning with an introduction to NanoBioMedicine and its application in gastrointestinal diseases, readers are guided through nanoscale drug delivery systems, nanoimaging techniques, and nanotheranostics in cancer treatment. Specific chapters address the role of nanotechnology in managing conditions like inflammatory bowel disease and celiac disease, while also exploring the integration of artificial intelligence and big data analytics.

  • Pediatric and Adolescent Gynecologic Surgery

    Management, Surgical Approaches, and Post-Operative Care
    • 1st Edition
    • Jennifer E Dietrich + 3 more
    • English
    Pediatric and Adolescent Gynecologic Surgery: Management, Surgical Approaches, and Post-Operative Care is an excellent and novel resource to understanding the management of adolescent gynecologic patients as written by top experts. The book offers detailed pearls of surgery and has a preoperative planning approach to abdominal, laparoscopic, and vaginal surgeries, as well as postoperative considerations. This is a comprehensive but easy-to-follow step-by-step surgical atlas for PAG surgeries organized in a historical context with the most recent research advances in the field. It provides expert views and perspectives with visuals to aid in learning useful to anyone in, or interested in, the field.

  • Hyponatremia and 40 Years of Controversy

    Looking Back and Moving Forward
    • 1st Edition
    • Richard H. Sterns
    • English
    Hyponatremia and 40 Years of Controversy: Looking Back and Moving Forward traces and probes the prolonged, contentious debate surrounding the treatment of severe hyponatremia, a low-sodium concentration in the blood that can result in severe brain damage if managed incorrectly.A mix of memoir and science, the book explains how slow correction of hyponatremia became accepted and how consensus was disrupted by assertions that caution was unnecessary and harmful. It scrutinizes the controversy, offers an approach to management, and unpacks research limitations – reminding us that what is believed true today may change tomorrow.Hyponatremi... and 40 Years of Controversy: Looking Back and Moving Forward is a vital resource for both experienced medical specialists and novice trainees. It explains the physiology of how hyponatremia happens and how it hurts. By offering historical insights, scientific rigor, and practical guidance, this book promises to enhance clinical decision making, foster new research, and improve outcomes in patients with hyponatremia.

  • Nanofiber Therapeutics

    Revolutionizing Cancer and Inflammation Management
    • 1st Edition
    • Neeraj Mishra + 2 more
    • English
    Nanofiber Therapeutics: Revolutionizing Cancer and Inflammation Management is a comprehensive resource designed to enrich knowledge, catalyze scientific advancements, empower patients, and inform policy decisions in nanomedicine. This book leverages the transformative potential of nanotechnology to combat cancer and inflammation, two of the most challenging health conditions today. The book explores the revolutionary potential of nanofiber-based therapeutics, aiming to develop innovative solutions that overcome existing treatment limitations and improve patient outcomes. It bridges the gap between basic scientific research and clinical application, synthesizing the latest advancements in nanofiber technology with insights from preclinical and clinical studies. Covering every facet of nanofiber therapies—from design and production to clinical applications—the book offers a comprehensive overview. It aims to educate healthcare professionals, researchers, policymakers, patients, and the public about the potential of nanofiber therapeutics, empowering stakeholders with the knowledge needed for informed decision-making and interdisciplinary collaboration. By highlighting cutting-edge research and technological innovations, this book inspires scientific curiosity and further research in the field. It fills a gap in the existing literature, laying the groundwork for future research and development, and driving advancements that could transform cancer and inflammation treatment.

  • Synthetic Biology and its Consequences in Present Healthcare

    • 1st Edition
    • Bhupendra G. Prajapati + 3 more
    • English
    Synthetic Biology enables the capability to manipulate and modify leaving cells and organisms to program them for specific purposes and has the potential to change the course of the healthcare sector. Synthetic Biology and its Consequences in Present Healthcare presents the latest findings and applications those in the healthcare sector need. Chapters cover a variety of synthetic biological tools in lifestyle diseases like obesity, heart disease, liver disease, type 2 diabetes and more. In addition, the vaccine development will cover DNA vaccines, synthetic and modified RNA-based vaccines, and personal vaccines for cancer, thus filling a gap in literature in the synthetic biology space. Written by international experts in the fields for those researching, practicing or studying in life sciences, biological sciences, including the synthetic biology domain.

  • Harnessing Artificial Intelligence-Enhanced Graph Models for Biological Discovery

    Unveiling Biological Frontiers
    • 1st Edition
    • Sudan Jha + 2 more
    • English
    Harnessing Artificial Intelligence-Enhance... Graph Models for Biological Discovery: Unveiling Biological Frontiers introduces revolutionary techniques that merge artificial intelligence with graph-based methods to uncover complex biological networks. Through detailed examples and case studies, the book provides researchers and practitioners the essential tools to analyze molecular interactions, identify key biomarkers, and hasten the discovery of novel therapeutics. Chapters delve into the sophisticated interplay between advanced AI techniques and graph models, specially designed to decode the intricacies of biological systems. By utilizing cutting-edge AI algorithms, readers can explore complex biological networks, forecast molecular interactions, and pinpoint new drug targets with exceptional precision.

  • Concepts of Combating Chemoresistance in Cancer Therapeutics

    • 1st Edition
    • Honey Goel + 3 more
    • English
    Concepts of Combating Chemoresistance in Cancer Therapeutics explores the fundamental issues and challenges related to cancer chemotherapeutics, emphasizing mechanisms and factors that lead to chemoresistance in various cancer types. This book provides current updates on novel paradigms and mechanisms responsible for cancer chemoresistance, presenting comprehensive information in 15 chapters. In addition to introducing principles, mechanisms, and monitoring strategies for cancer drug resistance, the book highlights the role of nanotechnology in diagnostics and point-of-care solutions for early detection, screening, and control. It is an invaluable resource for health professionals, scientists, researchers, and students seeking knowledge in this field.

  • Viral Hepatitis

    New Paradigms in Disease and Pathogenesis
    • 1st Edition
    • Esaki M. Shankar + 2 more
    • English
    Viral Hepatitis: New Paradigms in Disease Pathogenesis offers a comprehensive exploration of numerous mechanisms and emerging concepts in the pathogenesis of viral hepatitis. By integrating interdisciplinary perspectives and addressing emerging research questions, this book includes insights and practical solutions, bridging the gap between theory and application. The incorporation of the latest research findings and the unveiling of new insights within the content enriches the knowledge base of readers, positioning it as the ideal reference for viral hepatitis researchers. It offers a comprehensive overview of the subject matter, bridging research gaps and saving valuable time, while stimulating fresh research ideas.Moreover, it serves as an invaluable resource for clinicians, providing evidence-based research to support effective clinical decision-making, accurate diagnosis, and efficient management of viral hepatitis in the patient population.

  • Nanodots for Cancer Diagnosis and Treatment

    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Nanodots for Cancer Diagnosis and Treatment presents a pioneering exploration of nano-scale drug delivery systems that promise to revolutionize cancer care. This book, with insights from global scientific collaborations, delves into various nanodots employed in cancer diagnosis and treatment. The book provides a comprehensive overview of nanotechnology's role in cancer care, including the synthesis and characterization of nanodots and their importance in cancer imaging. It also covers various treatment options and offers practical suggestions for improving nanodots for cancer imaging and therapy, making it an invaluable resource for drug formulation experts, drug delivery specialists, oncologists, and translators.Nanodots enhance precision and effectiveness in delivering therapeutic agents to target sites within the body, representing a significant advancement in medical science.

  • A Complete Guide to Atrial Abnormalities

    From Computational Analysis to Clinical Applications
    • 1st Edition
    • Manuel Martínez-Sellés
    • English
    A Complete Guide to Atrial Abnormalities: From Computational Analysis to Clinical Applications provides background on all atrial conditions, helps clinicians differentiate between the main atrial diseases, and illustrates the clinical implications of each. Research into atrial dysfunctions has stalled in recent years. However, this book presents important research and prognostic information on the different types of atrial disorders. These include: Interatrial block; Atrial Dyssynchrony; Atrial fibrillation and atrial flutter; Bayés syndrome; Atrial enlargement; Atrial failure.This book further illuminates atrial involvement in all heart conditions, including cardiogenetic diseases, channelopathies and cardiomyopathies. As population aging increases the epidemic of cardiovascular disease, correct assessment of specific atrial diseases is even more essential in providing patients the best possible care in every situation. A Complete Guide to Atrial Abnormalities: From Computational Analysis to Clinical Applications includes computer-based analyses which cover how targeted, personalized care using big data might improve diagnosis, treatment therapies, and prevention of atrial abnormalities. These innovations include increased understanding of rhythm/rate control, risk of stroke, drugs, structure, imaging, and devices. This book is indispensable in understanding the complex interplay between atrial diseases and overall cardiovascular health.

  • Transcriptomics in Atherosclerosis

    Deciphering Molecular Signatures and Advancing Therapeutic Strategies
    • 1st Edition
    • Yvan Devaux + 1 more
    • English
    Transcriptomics in Atherosclerosis: Deciphering Molecular Signatures and Advancing Therapeutic Strategies explores how transcriptomic research is transforming our understanding and management of atherosclerosis. Bridging molecular biology and clinical medicine, it delves into the dynamic regulation of gene expression, the role of non-coding RNAs, and emerging insights from epitranscriptomics.T... book emphasizes advanced technologies such as single-cell and spatial transcriptomics, while embracing systems-level integration with other omic layers. It highlights how these approaches can reveal disease mechanisms, refine risk stratification, and guide the development of RNA-based diagnostics and therapies.Designed for researchers, clinicians, and translational scientists, this volume moves beyond generic overviews to present current methods, practical insights, and real-world challenges in the field. By doing so, it lays the groundwork for a new generation of precision strategies in cardiovascular care.

  • Emerging Technologies in the Healthcare System for Sustainable Development

    • 1st Edition
    • Kamil Reza Khondakar + 1 more
    • English
    Emerging Technologies in the Healthcare System for Sustainable Development explores the forefront of modern healthcare by shedding light on cutting-edge technologies such as artificial intelligence and their profound implications. The book places a distinct emphasis on sustainability, an increasingly pivotal point of discussion in public discourse. Centered around sustainability, the book adeptly underscores the significance and immediacy of incorporating emerging technologies into the healthcare landscape to effectively tackle the complexities of contemporary healthcare systems. Comprising 12 comprehensive chapters, Emerging Technologies in the Healthcare System for Sustainable Development distinguishes itself by its holistic approach, unwavering commitment to sustainability, relevance for interdisciplinary healthcare professionals, accessibility to non-technical readers, integration of research within real-world case studies, and its forward-thinking perspective. This book stands as an invaluable asset for healthcare professionals, researchers, scientists, practitioners, students, and anyone keen on expanding their knowledge within related domains.

  • Revolutionizing Digital Healthcare Through Artificial Intelligence and Automation

    Principles, Technologies, and Applications
    • 1st Edition
    • Alex Khang
    • English
    Revolutionizing Digital Healthcare Through Artificial Intelligence and Automation: Principles, Technologies, and Applications is a transformative exploration of how Artificial Intelligence (AI) and automation technologies are reshaping the healthcare landscape. In an era where precision, efficiency, and accessibility in medical services are paramount, this book delves into cutting-edge advancements in AI-powered diagnostics, wearable smart devices, and automated patient care systems. It stands as a beacon for innovators and healthcare professionals who aim to harness technology to streamline processes, improve patient outcomes, and create sustainable solutions in an ever-evolving industry.Beyond its focus on AI and automation, the book also examines the ethical implications and challenges of integrating technology into healthcare. It discusses strategies for implementing these technologies while ensuring patient privacy, maintaining human connection in care delivery, and navigating regulatory hurdles. With detailed case studies and forward-looking insights, the text provides a comprehensive roadmap for leveraging digital tools to shape the future of healthcare.

  • Innovative Targeting Strategies in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 4 more
    • English
    Innovative Targeting Strategies in Breast Cancer Therapy is a comprehensive reference addressing the challenge of non-specific drug distribution in the body, along with severe toxicity and adverse effects, by offering insights into targeted breast cancer treatment. It further educates researchers on formulating and developing novel carriers with target-specific attributes (such as targeted liposomes, nanoparticles, micelles, and dendrimers), contributing to a more refined approach to breast cancer. This book's content is presented in 12 chapters. The first chapters introduces the reader to the different breast cancer therapies followed by indepth information on targeting . Recognizing the need for targeted drug delivery in breast cancer treatment, this book presents an encompassing compilation of advanced research and formulation strategies. By focusing on effectively targeting cancer cells, the book mitigates dose-related toxicity associated with cytotoxic drugs, providing a comprehensive resource for improved treatment approaches. Research in oncology, pharmacology, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

  • Emerging Strategies in Cancer Metabolism

    Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids
    • 1st Edition
    • Neeraj Mishra + 2 more
    • English
    Emerging Strategies in Cancer Metabolism: Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids offers a revolutionary investigation of the complicated relationships between cancer metabolism and three crucial factors: the gut microbiota, reactive oxygen species (ROS), and the dysregulation of the short chain fatty acid (SCF) complex. This book adopts a thorough and interdisciplinary approach to untangle the intricate interactions between these components, providing fresh perspectives that fundamentally alters the understanding of cancer biology and therapy. In 14 chapters.Emerging Strategies in Cancer Metabolism: Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids provides a thorough investigation of the metabolic changes that occur inside cancer cells, illuminating how these changes promote tumour survival and progression, from introduction to future aspects. Researchers in cancer research, and gut microbiology will find this an essential reference.

  • Artificial Intelligence-Driven Precision Medicine for Triple Negative Breast Cancer

    Innovations and Insights in TNBC Management
    • 1st Edition
    • Sachin Namdeo Kothawade + 1 more
    • English
    Artificial Intelligence-Driven Precision Medicine for Triple-Negative Breast Cancer: Innovations and Insights in TNBC Management is a groundbreaking exploration into the transformative role of artificial intelligence in revolutionizing the management of triple-negative breast cancer (TNBC). In 19 chapters, this comprehensive guide navigates the intersection of cutting-edge technology and healthcare, offering insights that bridge the gap among medical professionals, researchers, and individuals affected by TNBC. Diving into the complexities of TNBC, this book unveils the potential of artificial intelligence (AI) in enhancing diagnostic accuracy, personalizing treatment strategies, and reshaping the landscape of breast cancer care. From radiomics and genomic data analysis to predictive modeling and patient engagement, each chapter unveils the latest innovations and provides the practical applications of AI to empower healthcare practitioners and improve patient outcomes. This book is a timely and valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge in the allied field.

  • Heart Failure in the Child and Young Adult

    From Bench to Bedside
    • 2nd Edition
    • Joseph Rossano + 5 more
    • English
    Heart Failure in the Child and Young Adult: From Bench to Bedside, Second Edition highlights unique aspects of heart failure in the young. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure and then progresses through diagnosis, management, treatment, and surgery, finally concluding with advanced special topics, including genetics, self-management, and nanomedicine.This new edition covers advancements in the field, including additional chapters and discussion on biomarkers, neuromuscular disease, quality of life, palliative care, and the impact of COVID-19 in myocarditis and multisystem inflammatory syndrome in children. It will serve as an indispensable reference to basic science researchers in cardiology, pediatrics, cardiologists, and pediatric cardiologists.

  • Biomarkers in Kidney Transplantation

    Clinical Aspects and Laboratory Determinations
    • 1st Edition
    • Dr Smita Pattanaik + 1 more
    • English
    Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers.Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.

  • Bladder Cancer Breakthroughs

    A Global Perspective on Diagnosis, Treatment, and Patient Care
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is a groundbreaking scientific resource that delves into the latest advancements in the diagnosis and treatment of bladder cancer, a prevalent malignancy affecting hundreds of thousands worldwide. This meticulously curated volume brings together contributions from leading scientists and healthcare professionals from around the globe, providing a comprehensive overview of contemporary understanding and innovative strategies in managing this complex disease. Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is not merely a collection of research findings; it is a vital resource that fosters a holistic perspective on patient-centered care. By synthesizing clinical expertise and evidence-based practices, this book aims to empower healthcare providers with the knowledge and tools needed to improve outcomes for individuals living with bladder cancer, ultimately contributing to the global fight against this challenging disease. This book serves as an essential guide for healthcare providers, including physicians, oncologists, immunologists, pharmacists, and physical therapists, striving to enhance patient care and treatment outcomes

  • Nitrogen Heterocycles in Cancer Therapy

    • 1st Edition
    • Sanjeev Kumar Sahu + 1 more
    • English
    Nitrogen Heterocycles in Cancer Therapy explores the vast array of recently discovered nitrogen-containing heterocyclic compounds utilized in combating cancer. This comprehensive work not only highlights the fundamentals of oncology but also explains the intricacies of designing, synthesizing, and understanding the anticancer mechanisms of these compounds. Spanning across 10 chapters, the book explores the principles underlying the design, synthesis, and anticancer mechanisms of nitrogen-containing heterocyclic compounds, drawing from the latest research findings. Its scope extends beyond molecular targeting to encompass the exploration of newly identified heterocyclic compounds with potential anticancer properties. A significant emphasis is placed on crucial evaluation techniques such as in-vitro cell culture and in-vivo animal models, providing insights into the performance of these compounds in combating cancer. Particularly noteworthy is the inclusion of clinical study reports detailing the efficacy of various drug candidates across different cancer conditions, coupled with an analysis of their global market impact and pharmacoeconomics. Offering profound insights, this book emerges as an indispensable resource for researchers, clinicians, and students alike.

  • Sleep and Cancer

    • 1st Edition
    • Maria Paola Mogavero + 3 more
    • English
    Sleep and Cancer compiles novel information on the interactions between sleep and cancer. The book highlights how prevention and treatment of sleep disturbances in clinical cancer practice helps prevent the onset of tumors and their comorbidities, both short- and long-term. It analyzes how sleep disorder treatment improves the response to antitumor therapy in the long term, presenting procedures regarding cognitive-behavioral therapy of sleep disorders that are often overlooked in the oncological field.In addition, the book suggests new therapeutic approaches in oncology that are based on the knowledge of sleep mechanisms, such as chronotherapy, use of melatonin as an adjuvant in chemo- and radiotherapy, and orexinergic drugs.

  • Climate Change and Disability

    A Collaborative Approach to a Sustainable Future
    • 1st Edition
    • Marcalee Alexander + 2 more
    • English
    Until recently, little attention has been paid to the concerns of people living with disabilities during extreme weather events and long-term climate changes. Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All delineates the general and specific risks of climate change for people living with disabilities and how we can use accessible approaches to mitigate, adapt, and control these risks, while maximizing opportunities for people living with disabilities. The book opens with an introduction on how we got here. The book continues with sections on actions and research, the physiologic impact of different disabilities, and discussions of specific continents and countries, where issues related to climate change exist. Education and advocacy are covered in detail, and the book wraps up with a section on action and research, detailing how to respond to extreme weather events including how various types of disabilities are impacted by different events.Climate Change and Disability: A Collaborative Approach to a Sustainable, Inclusive Future for All serves as a guide for a broad audience at the crossroads of environmental adaptation and human health. Physicians, as well as nurses, physical and occupational therapists, and other allied health professionals will find it valuable for tailoring care for people living with disabilities due to climate change. Advocates and individuals living with disabilities will gain insight into advocacy for inclusive policies and personal preparedness. Scientists and clinicians interested in the health and societal impacts of climate change will find it useful in informing their research and practice. Policymakers and politicians can utilize this resource to develop equitable climate strategies, ensuring that environmental justice concerns are inclusive.

  • Advancements in the Treatment and Prevention of Breast Cancer

    • 1st Edition
    • Dileep Kumar
    • English
    Advancements in the Treatment and Prevention of Breast Cancer highlights the significance of early detection, risk assessment, and comprehensive care in mitigating the burden of breast cancer within communities. It not only offers insights into the genetic basis of breast cancer susceptibility, familial risk assessment, and emerging genetic testing technologies but also empowers patients and their families with knowledge about available treatment options, clinical trials, and support resources.In 14 chapters this book provides an in-depth analysis of translational research focusing on understanding the etiology of breast cancer, elucidating potential avenues for primary prevention strategies. It offers a comprehensive overview of recent breakthroughs in understanding the molecular mechanisms underlying breast cancer development and discussing novel targeted treatment approaches derived from these advances but also discusses strategies for minimizing treatment-related toxicity in breast cancer management, including supportive care measures and personalized treatment approaches. This book is a valuable resource for anyone interested in the latest developments in breast cancer care and provides clear explanations of complex scientific topics and will offer insights that can help improve patient care and outcomes.

  • Fungal and Protozoan Carbonic Anhydrases

    • 1st Edition
    • Volume 57
    • English
    Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.Additiona... chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 129
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Artificial Intelligence in e-Health Framework, Volume 2

    Telemedicine Applications, Drug Delivery, Augmented Reality, and Robotics
    • 1st Edition
    • Sudip Paul + 1 more
    • English
    Artificial Intelligence in e-health Framework, Volume Two: Telemedicine Applications, Drug Delivery, Augmented Reality, and Robotics offers a comprehensive exploration of AI’s role in enhancing medical solutions. Through a focus on machine learning, deep learning, and their practical applications, this book aims to bridge the gap between theoretical advancements and real-world healthcare implementations. In addition to telemedicine advancements, the book explores AI-driven drug discovery, virtual and augmented reality innovations, robotics in medicine, and radiotherapy applications. It serves as an indispensable resource for professionals, researchers, and students eager to deepen their understanding of AI's contributions to modern healthcare.

  • ​​Environmental Greenness and Cardiovascular Health​

    • 1st Edition
    • William W. Aitken
    • English
    Environmental Greenness and Cardiovascular Health provides a comprehensive understanding of how environmental factors, particularly green spaces, impact cardiovascular health. The book bridges environmental science and medical research, offering insights into how greenness contributes to the prevention and management of cardiovascular diseases.Environment... Greenness and Cardiovascular Health begins with an introduction to cardiovascular disease and environmental factors, followed by discussions on defining and measuring greenness, historical perspectives, and the physiological and psychological benefits of green spaces. It also covers urban planning, disparities in access to green spaces, longitudinal studies, future research directions, and policy implications. Environmental Greenness and Cardiovascular Health benefits researchers, medical practitioners, urban planners, and policymakers by providing the latest methodologies, practical examples, and policy recommendations. It serves as an essential resource for understanding the intersection of environment and health, promoting informed strategies for improving cardiovascular health through environmental interventions.

  • Kratom

    History, Science and Therapeutic Potential
    • 1st Edition
    • Jack E. Henningfield + 2 more
    • English
    Kratom: History, Science and Therapeutic Potential is the first book to address the unregulated, widespread availability of kratom, with its weak opioid and stimulant effects, coupled with limited awareness of it by healthcare professionals. Kratom has great therapeutic utility and medicinal potential, but more study, caution, and possible regulation is needed. It discusses geographical sourcing, historical uses, current worldwide uses, and potential for treatment of other medical conditions. Most exciting for healthcare professionals will be the implications of this substance's potential for treatment of diseases like depression, ADHD, PTSD, and substance-use disorder, particularly opioid use disorder (OUD).Moreover, kratom and its active alkaloid mitragynine are getting remarkable attention at federal and local governments as more than eight million Americans consume this product annually. Yet, the paucity of information for researchers and clinicians is troublesome.

  • Ovarian Cancer

    Disease, Diagnosis, and Treatment
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    By providing a comprehensive overview of current research findings, emerging therapies, and clinical practices, Ovarian Cancer: Disease, Diagnosis and Treatment is an invaluable resource. It will not only enhance the understanding of ovarian cancer's complex biology among professionals but also guide them in applying this knowledge to improve patient outcomes The book delivers the key knowledge and information needs faced by the audience center around understanding the latest advances in the underlying pathogenesis and treatment of ovarian cancer. This encompasses a broad spectrum of requirements, from grasping the molecular and genetic factors driving ovarian cancer development to staying updated on the latest therapeutic strategies, including targeted therapies and immunotherapies. In 19 chapters Ovarian Cancer: Disease, Diagnosis and Treatment gives a timely and comprehensive coverage of advances in ovarian cancer therapy, particularly highlighting the development and utilization of Nanotheranostics technologies. This focus not only addresses a crucial and cutting-edge area of cancer treatment but also positions the book as a forward- thinking resource that delves into the potential of Nanotheranostics to revolutionize cancer diagnostics and therapy.Ovarian Cancer: Disease, Diagnosis and Treatment targets a specialized audience within the medical and scientific community, focusing on obstetricians and gynecologists, oncologists, cancer researchers, and importantly, patients with ovarian cancer. This audience selection underscores the project's dual aim of advancing scientific knowledge and directly benefiting patient care in the realm of ovarian cancer, bridging the gap between research, clinical application, and patient advocacy.

  • Encyclopedia of Evolutionary Biology

    • 2nd Edition
    • Claudia Augusta De Moraes Russo + 1 more
    • English
    Encyclopedia of Evolutionary Biology, Second Edition, Four Volume Set is a comprehensive resource containing approximately 215 chapters that covers all fundamental topics in evolutionary biology. Featuring a consistent chapter structure, this encyclopedia ensures easy navigation across the volumes. Each chapter effectively links concepts to specific systems and examples, making it an invaluable tool for anyone interested in applying evolutionary thinking to their field of study. This edition includes new or expanded topics such as human evolution, including cultural evolution and language, paleontology, the origins of life, mass extinction events, epigenetics, and metagenomics.The encyclopedia also delves into the evolution of behavior, game theory, kin selection, optimality, human microbiomes, and the diversification of viruses. With its broad coverage, this essential resource will engage readers across various educational levels, emphasizing the central role of evolutionary biology in the life sciences. It caters to a wide range of readers, from students to experienced professionals, by offering both introductory chapters and in-depth analyses.

  • New Opioid Receptor Modulators and Agonists

    Relevance for Pain and Opioid Use Disorder Management
    • 1st Edition
    • Alan David Kaye + 1 more
    • English
    New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.

  • Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma

    • 1st Edition
    • Rajeev Sharma + 4 more
    • English
    Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

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