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Elsevier

Books in Biotechnology

Exploring genetic engineering, cell culture, and bioprocessing, this collection supports researchers and industry professionals developing new therapies, diagnostics, and sustainable bio products. It features innovative techniques, case studies, and regulatory considerations, enabling advancements in healthcare, agriculture, and environmental solutions within a rapidly evolving biotech landscape.

  • Specialty Thermoplastics

    • 1st Edition
    • Prakash Trivedi
    • English

  • Biotechnology of Microbial Enzymes

    Production, Biocatalysis, and Industrial Applications
    • 2nd Edition
    • Goutam Brahmachari
    • English
    Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications, Second Edition provides a complete survey of the latest innovations on microbial enzymes, highlighting biotechnological advances in their production and purification along with information on successful applications as biocatalysts in several chemical and industrial processes under mild and green conditions. The application of recombinant DNA technology within industrial fermentation and the production of enzymes over the last three decades have produced a host of useful chemical and biochemical substances. The power of these technologies results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology, all of which is covered insightfully and in-depth within the book. This fully revised, second edition is updated to address the latest research developments and applications in the field, from microbial enzymes recently applied in drug discovery to penicillin biosynthetic enzymes and penicillin acylase, xylose reductase, and microbial enzymes used in antitubercular drug design. Across the chapters, the use of microbial enzymes in sustainable development and production processes is fully considered, with recent successes and ongoing challenges highlighted.

  • Magnetic Resonance Imaging of The Pelvis

    A Practical Approach
    • 1st Edition
    • Neeraj Lalwani
    • English
    Magnetic Resonance Imaging of The Pelvis: A Practical Approach presents comprehensive information to deal withcommonly encountered pelvic pathologies. The content is developed by disease-focused experts aiming to share theirexperience to make the information easily applicable to clinical setting and research. The book covers a wide range of pelvic pathologies, and each chapter focuses on problem-solving approaches andincludes tips and advice for multiple real-world scenarios. It also provides comprehensive-yet-ta... protocols, clearguidelines for indications, a detailed discussion of pathologies, descriptions of important differential diagnoses, and pitfalls and their solutions. It is a valuable resource for radiologists, researchers, clinicians, and members of medical and biomedical fields who needto understand better how to use MRI to base their diagnosis or advance their research work.

  • Secretory Proteins

    • 1st Edition
    • Volume 133
    • Rossen Donev
    • English
    Secretory Proteins, Volume 133 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, including chapters on Proprotein Convertases regulate trafficking and maturation of key proteins within the secretory pathway, Secretory Proteins in Cancer Diagnosis, Senescent Cells and SASP in Cancer Microenvironment: new approaches in cancer therapy, Autophagy for secretory protein: Therapeutic targets in cancer, Secretory proteins and pathways of secretion of osteosarcoma, Monocyte secretory proteins as drug targets for arresting progression of atherosclerosis, The secretory phenotypes of envenomed cells: insights into venom cytotoxicity, Macromolecules for secretory pathway in SARS-CoV-2 infection, and much more. Other sections cover Exploring the role of secretory proteins in the human infectious diseases diagnosis and therapeutics, Secretory proteins in orchestration of microbial pathogenesis- the curious case of Staphylococcus aureus, Influence of pathological mutations in Aspartylglucosylamin... Deaspartylase causing Aspartylglucosaminur... an in silico approach, and Change in conformational dynamics of Lipase A secretory protein upon mutation causing Wolman disease.

  • Biotechnology for Beginners

    • 3rd Edition
    • Reinhard Renneberg
    • English
    Biotechnology for Beginners, Third Edition presents the latest developments in the evolving field of biotechnology which has grown to such an extent over the past few years that increasing numbers of professional’s work in areas that are directly impacted by the science. This book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy and animal science. This book will also appeals to lay readers who do not have a scientific background but are interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Loroch discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome.

  • Green Sustainable Process for Chemical and Environmental Engineering and Science

    Methods for Producing Smart Packaging
    • 1st Edition
    • Tariq Altalhi + 2 more
    • English
    Green Sustainable Process for Chemical and Environmental Engineering and Science: Methods for Producing Smart Packaging covers the latest advances in the development and production of smart packaging. The book addresses issues related to the production of smart packaging, including marketing and environmental impacts of these new products. The book demonstrates how modern packaging goes beyond protecting food against physical, chemical, and biological damage, and that scientific advances now enable producing functional packaging that prolongs product quality, preserves physical and chemical properties, produces greater protection against transportation shocks, and makes food more compact and easily recycled.

  • Smartphone Apps for Health and Wellness

    • 1st Edition
    • John Higgins + 1 more
    • English
    Smartphone Apps for Health and Wellness helps readers navigate the world of smartphone apps to direct them to those which have had the best medical evidence in obtaining the users’ goal. The book covers the history of apps, how they work, and specific apps to improve health and wellness in order to improve patients outcomes. It discusses several types of apps, including apps for medical care, sleeping, relaxation, nutrition, exercise and weight loss. In addition, sections present the features of a good app to empower readers to make their own decision when evaluating which one to use. This is a valuable resource for clinicians, physicians, researchers and members of biomedical field who are interested in taking advantage of smartphone apps to improve overall health and wellness of patients.

  • Foot and Ankle Biomechanics

    • 1st Edition
    • William Ledoux + 1 more
    • English
    Foot and Ankle Biomechanics is a one source, comprehensive and modern reference regarding foot and ankle biomechanics. This text serves as both a master reference for foot biomechanics, presenting a clear state of the research and capabilities in the field. The customers for this book will be those looking for information on foot and ankle biomechanics for a range of applications; for example, designers of orthotics.

  • Biomedical Defense Principles to Counter DNA Deep Hacking

    • 1st Edition
    • Rocky Termanini
    • English
    Biomedical Defense Principles to Counter DNA Deep Hacking presents readers with a comprehensive look at the emerging threat of DNA hacking. Dr. Rocky Termanini goes in-depth to uncover the erupting technology being developed by a new generation of savvy bio-hackers who have skills and expertise in biomedical engineering and bioinformatics. The book covers the use of tools such as CRISPR for malicious purposes, which has led agencies such as the U.S. Office of the Director of National Intelligence to add gene editing to its annual list of threats posed by "weapons of mass destruction and proliferation." Readers will learn about the methods and possible effects of bio-hacking attacks, and, in turn the best methods of autonomic and cognitive defense strategies to detect, capture, analyze, and neutralize DNA bio-hacking attacks, including the versatile DNA symmetrical AI Cognitive Defense System (ACDS). DNA bio-hackers plan to destroy, distort and contaminate confidential, healthy DNA records and potentially create corrupted genes for erroneous diagnosis of illnesses, disease genesis and even wrong DNA fingerprinting for criminal forensics investigations.

  • Omics Approaches and Technologies in COVID-19

    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19. This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling andsimulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development. This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects.

  • State of the Art in Neural Networks and Their Applications

    Volume 2
    • 1st Edition
    • Jasjit S. Suri + 1 more
    • English
    State of the Art in Neural Networks and Their Applications, Volume Two presents the latest advances in artificial neural networks and their applications across a wide range of clinical diagnoses. The book provides over views and case studies of advances in the role of machine learning, artificial intelligence, deep learning, cognitive image processing, and suitable data analytics useful for clinical diagnosis and research applications. The application of neural network, artificial intelligence and machine learning methods in biomedical image analysis have resulted in the development of computer-aided diagnostic (CAD) systems that aim towards the automatic early detection of several severe diseases. State of the Art in Neural Networks and Their Applications is presented in two volumes. Volume One: Neural Networks in Oncology Imaging covers lung cancer, prostate cancer, and bladder cancer. Volume Two: Neural Networks in Brain Disorders and Other Diseases covers autism spectrum disorder, Alzheimer’s disease, attention deficit hyperactivity disorder, hypertension, and other diseases. Written by experienced engineers in the field, these two volumes will help engineers, computer scientists, researchers, and clinicians understand the technology and applications of artificial neural networks.

  • Data Science for Genomics

    • 1st Edition
    • Amit Kumar Tyagi + 1 more
    • English
    Data Science for Genomics presents the foundational concepts of data science as they pertain to genomics, encompassing the process of inspecting, cleaning, transforming, and modeling data with the goal of discovering useful information, suggesting conclusions and supporting decision-making. Sections cover Data Science, Machine Learning, Deep Learning, data analysis, and visualization techniques. The authors then present the fundamentals of Genomics, Genetics, Transcriptomes and Proteomes as basic concepts of molecular biology, along with DNA and key features of the human genome, as well as the genomes of eukaryotes and prokaryotes. Techniques that are more specifically used for studying genomes are then described in the order in which they are used in a genome project, including methods for constructing genetic and physical maps. DNA sequencing methodology and the strategies used to assemble a contiguous genome sequence and methods for identifying genes in a genome sequence and determining the functions of those genes in the cell. Readers will learn how the information contained in the genome is released and made available to the cell, as well as methods centered on cloning and PCR.

  • Fractional Order Systems and Applications in Engineering

    • 1st Edition
    • Dumitru Baleanu + 2 more
    • English
    Fractional Order Systems and Applications in Engineering presents the use of fractional calculus (calculus of non-integer order) in the description and modelling of systems and in a range of control design and practical applications. The book covers the fundamentals of fractional calculus together with some analytical and numerical techniques, and provides MATLAB® codes for the simulation of fractional-order control (FOC) systems. The use of fractional calculus can improve and generalize well-established control methods and strategies. Many different FOC schemes are presented for control and dynamic systems problems. These extend to the challenging control engineering design problems of robust and nonlinear control. Practical material relating to a wide variety of applications including, among others, mechatronics, civil engineering, irrigation and water management, and biological systems is also provided. All the control schemes and applications are presented with either system simulation results or real experimental results, or both. Fractional Order Systems and Applications in Engineering introduces readers to the essentials of FOC and imbues them with a basic understanding of FOC concepts and methods. With this knowledge readers can extend their use of FOC in other industrial system applications, thereby expanding their range of disciplines by exploiting this versatile new set of control techniques.

  • Tissue Engineering

    • 3rd Edition
    • Clemens van Blitterswijk + 1 more
    • English
    Tissue Engineering, Third Edition provides a completely revised release with sections focusing on Fundamentals of Tissue Engineering and Tissue Engineering of Selected Organs and Tissues. Key chapters are updated with the latest discoveries, including coverage of new areas (skeletal TE, ophthalmology TE, immunomodulatory biomaterials and immune systems engineering). The book is written in a scientific language that is easily understood by undergraduate and graduate students in basic biological sciences, bioengineering and basic medical sciences, and researchers interested in learning about this fast-growing field.

  • Mind Mapping and Artificial Intelligence

    • 1st Edition
    • Jose Maria Guerrero
    • English
    In the near future, we will see an increase in the development and use of all sorts of AI applications. Some of the more promising areas will be Finance, Healthcare, IoT, Manufacturing, Journalism, and Cybersecurity. Many of these applications generate a great amount of complex information. Natural Language Understanding is one of the most clear examples. Traditional ways of visualizing complex information, namely linear text, web pages and hyperlink-based applications, have serious productivity problems. Users need a lot of time to visualize the information and have problems seeing the whole picture of the results. Mind mapping is probably the only way of reducing the problems inherent in these traditional ways of visualizing complex information. Most people have no clear idea about the advantages of mind mapping or the problems created by the traditional ways of visualizing complex information. The goal of Mind Mapping and Artificial Intelligence is to provide readers with an introduction to mind mapping and artificial intelligence, to the problems of using traditional ways of visualizing complex information and as an introduction to mind mapping automation and its integration into Artificial Intelligence applications such as NLU and others. As more applications of Artificial Intelligence are developed in the near future, the need for the improvement of the visualization of the information generated will increase exponentially. Information overload will soon also happen in AI applications. This will diminish the advantages of using AI. Author José Maria Guerrero is a long-time expert in mind mapping and visualization techniques. In this book he also introduces readers to MindManager mind mapping software, which can considerably reduce the problems associated with the interpretation of complex information generated by Artificial Intelligence software.

  • 3D Printing in Medicine

    • 2nd Edition
    • Deepak M. Kalaskar
    • English
    3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand.

  • Neural Engineering Techniques for Autism Spectrum Disorder, Volume 2

    Diagnosis and Clinical Analysis
    • 1st Edition
    • Jasjit S. Suri + 1 more
    • English
    Neural Engineering for Autism Spectrum Disorder, Volume Two: Diagnosis and Clinical Analysis presents the latest advances in neural engineering and biomedical engineering as applied to the clinical diagnosis and treatment of Autism Spectrum Disorder (ASD). Advances in the role of neuroimaging, magnetic resonance spectroscopy, MRI, fMRI, DTI, video analysis of sensory-motor and social behaviors, and suitable data analytics useful for clinical diagnosis and research applications for Autism Spectrum Disorder are covered, including relevant case studies. The application of brain signal evaluation, EEG analytics, fuzzy model and temporal fractal analysis of rest state BOLD signals and brain signals are also presented. A clinical guide for general practitioners is provided along with a variety of assessment techniques such as magnetic resonance spectroscopy. The book is presented in two volumes, including Volume One: Imaging and Signal Analysis Techniques comprised of two Parts: Autism and Medical Imaging, and Autism and Signal Analysis. Volume Two: Diagnosis and Treatment includes Autism and Clinical Analysis: Diagnosis, and Autism and Clinical Analysis: Treatment.

  • AI Assurance

    Towards Trustworthy, Explainable, Safe, and Ethical AI
    • 1st Edition
    • Feras A. Batarseh + 1 more
    • English
    AI Assurance: Towards Trustworthy, Explainable, Safe, and Ethical AI provides readers with solutions and a foundational understanding of the methods that can be applied to test AI systems and provide assurance. Anyone developing software systems with intelligence, building learning algorithms, or deploying AI to a domain-specific problem (such as allocating cyber breaches, analyzing causation at a smart farm, reducing readmissions at a hospital, ensuring soldiers’ safety in the battlefield, or predicting exports of one country to another) will benefit from the methods presented in this book. As AI assurance is now a major piece in AI and engineering research, this book will serve as a guide for researchers, scientists and students in their studies and experimentation. Moreover, as AI is being increasingly discussed and utilized at government and policymaking venues, the assurance of AI systems—as presented in this book—is at the nexus of such debates.

  • Encyclopedia of Sensors and Biosensors

    • 1st Edition
    • Roger Narayan
    • English
    **Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Encyclopedia of Sensors and Biosensors, Four Volume Set provides unique foundational level information on the rapidly growing sensor community. The book covers innovations in materials, designs, devices and software that find their way into new types of sensors. Sections include over 1000 color images, including representations of sensor design, sensor manufacturing, and assessments of sensor performance. In addition, applications of sensors in healthcare, food safety, environmental engineering and other fields are discussed, making this a truly interdisciplinary work. The book is structured using a logical and thematic approach, with chapters taking a balanced viewpoint, listing both advantages and disadvantages.Perfec... for those learning their trade in both academia and industry, this vital reference work will serve many groups, including chemists, engineers, biological scientists, clinicians, and industrial researchers.

  • Advanced Technologies and Polymer Materials for Surgical Sutures

    • 1st Edition
    • Sabu Thomas + 4 more
    • English
    Polymeric materials offer a high level of versatility due to the range of applications possible within the biomedical and clinical fields – including wound closure - particularly in comparison to metals or ceramics. These specialised materials also allow for a diverse array of therapeutic effects. Although there have been advances in improving polymeric materials for surgical sutures, there is little information available regarding improving the therapeutic value of sutures, and advanced technologies used to implement this improvement. Advanced Technologies and Polymer Materials for Surgical Sutures provides thorough coverage on suture materials with improved mechanical and therapeutic properties that can improve quality of life; chapter topics include drug-releasing kinetics of sutures, shape memory polymer sutures and future trends.This book is a useful resource for academics and researchers in the materials science and biomedical engineering fields, as well as professionals in biomaterials and biotextiles development and clinicians looking to learn more about suture material properties and suture/body interactions.

  • Semantic Models in IoT and eHealth Applications

    • 1st Edition
    • Sanju Tiwari + 2 more
    • English
    Semantic Models in IoT and eHealth Applications explores the key role of semantic web modeling in eHealth technologies, including remote monitoring, mobile health, cloud data and biomedical ontologies. The book explores different challenges and issues through the lens of various case studies of healthcare systems currently adopting these technologies. Chapters introduce the concepts of semantic interoperability within a healthcare model setting and explore how semantic representation is key to classifying, analyzing and understanding the massive amounts of biomedical data being generated by connected medical devices. Continuous health monitoring is a strong solution which can provide eHealth services to a community through the use of IoT-based devices that collect sensor data for efficient health diagnosis, monitoring and treatment. All of this collected data needs to be represented in the form of ontologies which are considered the cornerstone of the Semantic Web for knowledge sharing, information integration and information extraction.

  • De Novo Peptide Design

    Principles and Applications
    • 1st Edition
    • Vibin Ramakrishnan + 2 more
    • English
    De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry. In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents.

  • Computational Models in Biomedical Engineering

    Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software
    • 1st Edition
    • Milos Kojic + 2 more
    • English
    Computational Models in Biomedical Engineering: Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software discusses novel computational methodologies developed by the authors that address a variety of topics in biomedicine, with concepts that rely on the so-called smeared physical field built into the finite element method. A new and straightforward methodology is represented by their Kojic Transport Model (KTM), where a composite smeared finite element (CSFE) as a FE formulation contains different fields (e.g., drug concentration, electrical potential) in a composite medium, such as tissue, which includes the capillary and lymphatic system, different cell groups and organelles. The continuum domains participate in the overall model according to their volumetric fractions. The governing laws and material parameters are assigned to each of the domains. Furthermore, the continuum fields are coupled at each FE node by connectivity elements which take into account biological barriers such as vessel walls and cells.

  • Disorders of Protein Synthesis

    • 1st Edition
    • Volume 132
    • Rossen Donev
    • English
    Disorders of Protein Synthesis, Volume 132 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Predictive Modeling in Biomedical Data Mining and Analysis

    • 1st Edition
    • Sudipta Roy + 4 more
    • English
    Predictive Modeling in Biomedical Data Mining and Analysis presents major technical advancements and research findings in the field of machine learning in biomedical image and data analysis. The book examines recent technologies and studies in preclinical and clinical practice in computational intelligence. The authors present leading-edge research in the science of processing, analyzing and utilizing all aspects of advanced computational machine learning in biomedical image and data analysis. As the application of machine learning is spreading to a variety of biomedical problems, including automatic image segmentation, image classification, disease classification, fundamental biological processes, and treatments, this is an ideal reference. Machine Learning techniques are used as predictive models for many types of applications, including biomedical applications. These techniques have shown impressive results across a variety of domains in biomedical engineering research. Biology and medicine are data-rich disciplines, but the data are complex and often ill-understood, hence the need for new resources and information.

  • Biotechnology in Healthcare, Volume 2

    Applications and Initiatives
    • 1st Edition
    • Debmalya Barh
    • English
    Biotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized healthcare in the last two decades by developing and introducing novel diagnostics, therapeutics, and preventive measures; whether it is noncommunicable or communicable disease, primary or secondary care, or public health, it has shown its immense potential to provide a solution to the healthcare providers, physicians, and allied health care professionals.The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.

  • Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach

    • 1st Edition
    • Anirudh Nath + 2 more
    • English
    Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult.

  • Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine

    • 1st Edition
    • Alok Pandya + 2 more
    • English
    Design, Principle and Application of Self-Assembled Nanobiomaterials in Biology and Medicine discusses recent advances in science and technology using nanoscale units that show the novel concept of combining nanotechnology with various research disciplines within both the biomedical and medicine fields. Self-assembly of molecules, macromolecules, and polymers is a fascinating strategy for the construction of various desired nanofabrication in chemistry, biology, and medicine for advanced applications. It has a number of advantages: (1) It is involving atomic-level modification of molecular structure using bond formation advanced techniques of synthetic chemistry. (2) It draws from the enormous wealth of examples in biology for the development of complex, functional structures. (3) It can incorporate biological structures directly as components in the final systems. (4) It requires that the target self-assembled structures be thermodynamically most stable with relatively defect-free and self-healing. In this book, we cover the various emerging self-assembled nanostructured objects including molecular machines, nano-cars molecular rotors, nanoparticles, nanosheets, nanotubes, nanowires, nano-flakes, nano-cubes, nano-disks, nanorings, DNA origami, transmembrane channels, and vesicles. These self-assembled materials are used for sensing, drug delivery, molecular recognition, tissue engineering energy generation, and molecular tuning.

  • Interactions of Bone with Orthopedic Implants and Possible Failures

    • 1st Edition
    • Amirhossein Goharian + 1 more
    • English
    Interactions of Bone with Orthopedic Implants and Possible Failures focuses on the mechanical and biological issues that may cause failure of the implant-bone construct. The book provides discussions on the effects of the design, process, surface and other engineering parameters of implants and their interaction with bone tissue. For implant designers, it is highly crucial to know the final effects of what they are designing or aiming to design, along with performance parameters. It is also crucial for orthopedic surgeons to be familiar with the background of the design and process parameters of the implant they will insert in a patient’s body. With the understanding brought forth in this book, surgeons can have better implant options and implant designers can create and develop new implant designs. This book can also help biomechanical and mechanical engineers who are normally dealing with testing and analysis of orthopedic implants examine the biomechanical behavior of the implants and their interaction with bone tissue.

  • Nuclear Medicine and Molecular Imaging

    • 1st Edition
    • Alberto Signore
    • English
    Nuclear Medicine and Molecular Imaging offers complete coverage of this exciting and key area of biomedicine, seamlessly fusing the science behind nuclear medicine with the clinical aspects of diagnostic imaging. Beginning with sections on the physics related to nuclear medicine, radiation biology/safety, and instrumentation/qual... control, it then covers radiochemistry and the development of new radionuclide therapy/tracers, and basic techniques such as positron emission tomography (PET) and single photon emission computed tomography (SPECT). The focus then shifts to the clinical aspects, with sections on clinical/preclinical nuclear imaging (structured via organ system such as gastrointestinal, cardiovascular, pulmonary, etc.), as well as other in vivo molecular imaging techniques such as optical imaging, digital image analysis (radiomics), as well as the increasing use of artificial intelligence (AI) in diagnostics. No other publication provides such a complete overview of the field, with most choosing to focus either on physics or imaging. In most cases, preclinical/experime... imaging is treated separately from clinical imaging. Nuclear Medicine and Molecular Imaging brings it all together into a complete, 4-volume, foundational resource for researchers and medical professionals specializing in this exciting area.

  • Coronavirus Drug Discovery

    Volume 2: Antiviral Agents from Natural Products and Nanotechnological Applications
    • 1st Edition
    • Chukwuebuka Egbuna
    • English
    Coronavirus Drug Discovery, Volume Two: Antiviral Agents from Natural Products and Nanotechnological Applications presents detailed information on drug discovery against COVID-19. Sections in this volume present chapters that focus on the various antiviral agents from natural products that have the propensity to be used as chemical scaffolds for the development of drugs against COVID-19. Also captured are the dietary sources of antioxidant bioactives that may help boost the immune system for the management of COVID-19. Other chapters describe the application of nanotechnology for efficient and effective delivery of drugs against COVID-19. Written by global team of experts, this book is an excellent resource for drug developers, medicinal chemists, pharmaceutical companies in R&D and research institutes in both academia and industry.

  • Green Sustainable Process for Chemical and Environmental Engineering and Science

    Green Composites: Preparation, Properties and Allied Applications
    • 1st Edition
    • Tariq Altalhi + 1 more
    • English
    Green Sustainable Process for Chemical and Environmental Engineering and Science, the latest release in the Green Composites: Preparation, Properties and Allied Applications series, deals with the most promising aspects of green composites. The book presents in-depth and updated literature related to the manufacturing of green composites and their properties and discusses special features of green composites and their applications in daily life. All green composites covered in this work are polymeric and of bio-origin. The book also provides industrial applications of green composites. Topics covered include the use of green composites, vegetable packing, foam, blends, rubber, solar cells, adhesives and 3D printing.

  • Multi-Chaos, Fractal and Multi-Fractional Artificial Intelligence of Different Complex Systems

    • 1st Edition
    • Yeliz Karaca + 4 more
    • English
    Multi-Chaos, Fractal and Multi-Fractional Artificial Intelligence of Different Complex Systems addresses different uncertain processes inherent in the complex systems, attempting to provide global and robust optimized solutions distinctively through multifarious methods, technical analyses, modeling, optimization processes, numerical simulations, case studies as well as applications including theoretical aspects of complexity. Foregrounding Multi-chaos, Fractal and Multi-fractional in the era of Artificial Intelligence (AI), the edited book deals with multi- chaos, fractal, multifractional, fractional calculus, fractional operators, quantum, wavelet, entropy-based applications, artificial intelligence, mathematics-informed and data driven processes aside from the means of modelling, and simulations for the solution of multifaceted problems characterized by nonlinearity, non-regularity and self-similarity, frequently encountered in different complex systems. The fundamental interacting components underlying complexity, complexity thinking, processes and theory along with computational processes and technologies, with machine learning as the core component of AI demonstrate the enabling of complex data to augment some critical human skills. Appealing to an interdisciplinary network of scientists and researchers to disseminate the theory and application in medicine, neurology, mathematics, physics, biology, chemistry, information theory, engineering, computer science, social sciences and other far-reaching domains, the overarching aim is to empower out-of-the-box thinking through multifarious methods, directed towards paradoxical situations, uncertain processes, chaotic, transient and nonlinear dynamics of complex systems.

  • Lessons from COVID-19

    Impact on Healthcare Systems and Technology
    • 1st Edition
    • Arturas Kaklauskas + 3 more
    • English
    Lessons from COVID-19: Impact on Healthcare Systems and Technology uncovers the impact that COVID-19 has made on healthcare and technology industries. State-of-the-art case studies, empirical research, and new trends in technology-mediated solution are discussed to help inform and guide readers in understanding the effects that the COVID-19 outbreak has had across healthcare and technology industries. The book discusses challenges to identify vaccines, changes in legislation on clinical trials and re-purposing of licensed drugs, effects on primary healthcare, best practices adopted by different countries to control the pandemic, and different effects on patients within diverse age groups and comorbidities. In addition, the book covers technology-mediated solutions and infrastructures applied, digital transformations, modeling techniques, statistical projections, and the benefits and use of cloud computing and artificial intelligence. This is a valuable resource for healthcare professionals, medical doctors, researchers and graduate students from both biomedical and technological fields who are interested in learning more about the use of new technologies to fight a pandemic.

  • Methods of Mathematical Modelling

    Infectious Diseases
    • 1st Edition
    • Harendra Singh + 2 more
    • English
    Methods of Mathematical Modeling: Infectious Diseases presents computational methods related to biological systems and their numerical treatment via mathematical tools and techniques. Edited by renowned experts in the field, Dr. Hari Mohan Srivastava, Dr. Dumitru Baleanu, and Dr. Harendra Singh, the book examines advanced numerical methods to provide global solutions for biological models. These results are important for medical professionals, biomedical engineers, mathematicians, scientists and researchers working on biological models with real-life applications. The authors deal with methods as well as applications, including stability analysis of biological models, bifurcation scenarios, chaotic dynamics, and non-linear differential equations arising in biology. The book focuses primarily on infectious disease modeling and computational modeling of other real-world medical issues, including COVID-19, smoking, cancer and diabetes. The book provides the solution of these models so as to provide actual remedies.

  • Genomic Medicine Skills and Competencies

    • 1st Edition
    • Dhavendra Kumar
    • English
    Genomic Medicine Skills and Competencies discusses core and practical aspects of genetic and genomic education and training for medical field. Many aspects of genomic applications in science, biotechnology, clinical medicine and healthcare require core and specialist knowledge, skills development and competencies for carrying out diverse tasks. Several knowledge-based courses and opportunities for skills and competencies development and assessment are now available and the main required subjects are discussed in this volume. The book focuses on all major aspects of genetic and genomic education training that are currently offered and evaluated and is a valuable resource for researchers, clinicians, physicians, nurses, genetic counselors, bioinformatics technicians, and other professionals who are interested in learning more about such promising field.

  • Applied Environmental Metabolomics

    Community Insights and Guidance from the Field
    • 1st Edition
    • David J. Beale + 3 more
    • English
    Applied Environmental Metabolomics: Community Insights and Guidance from the Field brings together contributions from global experts who have helped to define and develop the exciting and rapid advances that are taking place in the field of environmental metabolomics. This book is aimed at expert users, students, researchers, and academics in metabolomics and systems biology. It not only demonstrates the best practice in experimental design but also provides insight into state-of-the-art instrumentation and the depth of analysis one can expect to get by using various sampling, chromatographic, mass spectrometric, and nuclear magnetic resonance (NMR) techniques. Common experimental and technical pitfalls are also highlighted. This book provides a unique insight into the world of environmental metabolomics and will help the practicing scientist avoid repeating similar costly mistakes, steering them efficiently toward the generation of high-quality data and high-impact publications.

  • Advances in Cardiovascular Technology

    New Devices and Concepts
    • 1st Edition
    • Jamshid Karimov + 2 more
    • English
    Advances in Cardiovascular Technology: New Devices and Concepts is a comprehensive reference for cardiovascular devices of all types. For engineers, this book provides a basic understanding of underlying pathologies and their prevalence/incidence... It also covers what devices are available, how they are clinically used, and their impact on pathophysiology. In addition, the book presents the constraints imposed on device design and manufacture by the environment in which it is used (e.g., exposure to tissues within the body, blood in particular) and the primary requirements for each specific type of device, including its durability and resistance to fatigue. For clinicians, this book contains information on primary engineering challenges, the types of devices available, their advantages and disadvantages, and the (current and emerging) tools and materials available to device designers.

  • Advances in Plant Tissue Culture

    Current Developments and Future Trends
    • 1st Edition
    • Avinash Chandra Rai + 3 more
    • English
    Advances in Plant Tissue Culture: Current Developments and Future Trends provides a complete and up-to-date text on all basic and applied aspects of plant tissue cultures and their latest application implications. It will be beneficial for students and early-career researchers of plant sciences and plant/agricultural biotechnology. Plant tissue culture has emerged as a sustainable way to meet the requirements of fresh produces, horticultural crops, medicinal or ornamental plants. Nowadays, plant tissue culture is an emerging filed applied in various aspects, including sustainable agriculture, plant breeding, horticulture and forestry. This book covers the latest technology, broadly applied for crop improvement, clonal propagation, Somatic hybridization Embryo rescue, Germplasm conservation, genetic conservation, or for the preservation of endangered species. However, these technologies also play a vital role in breaking seed dormancy over conventional methods of conservation.

  • Algae-Based Biomaterials for Sustainable Development

    Biomedical, Environmental Remediation and Sustainability Assessment
    • 1st Edition
    • Huu Hao Ngo + 4 more
    • English
    Biomass, Biofuels, and Biochemicals: Algae-Based Biomaterials for Sustainable Development, Biomedical, Environmental Remediation and Sustainability Assessment, a new release in the Biomass, Biofuels, and Biochemicals series, covers algae-based biomaterials—the green and renewable material that can be produced from various micro- and macro-algae species and utilized for several applications, including biomedical healthcare and environmental remediation. The book provides assessments of the current development of algae-based biomaterials, delivering information on diverse feedstocks and technologies for biomaterial production with a perspective surrounding sustainable development. In addition, circular bioeconomy aspects are included, giving researchers a comprehensive, sustainable development view. This valuable addition to the series delivers a much-needed reference for today’s applications in biomedical and environmental remediation.

  • Big Data Analytics for Healthcare

    Datasets, Techniques, Life Cycles, Management, and Applications
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Big Data Analytics and Medical Information Systems presents the valuable use of artificial intelligence and big data analytics in healthcare and medical sciences. It focuses on theories, methods and approaches in which data analytic techniques can be used to examine medical data to provide a meaningful pattern for classification, diagnosis, treatment, and prediction of diseases. The book discusses topics such as theories and concepts of the field, and how big medical data mining techniques and applications can be applied to classification, diagnosis, treatment, and prediction of diseases. In addition, it covers social, behavioral, and medical fake news analytics to prevent medical misinformation and myths. It is a valuable resource for graduate students, researchers and members of biomedical field who are interested in learning more about analytic tools to support their work.

  • Protein Design and Structure

    • 1st Edition
    • Volume 130
    • Rossen Donev
    • English
    Protein Design and Structure, Volume 130 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Artificial Intelligence and Machine Learning for EDGE Computing

    • 1st Edition
    • Rajiv Pandey + 3 more
    • English
    Artificial Intelligence and Machine Learning for Predictive and Analytical Rendering in Edge Computing focuses on the role of AI and machine learning as it impacts and works alongside Edge Computing. Sections cover the growing number of devices and applications in diversified domains of industry, including gaming, speech recognition, medical diagnostics, robotics and computer vision and how they are being driven by Big Data, Artificial Intelligence, Machine Learning and distributed computing, may it be Cloud Computing or the evolving Fog and Edge Computing paradigms. Challenges covered include remote storage and computing, bandwidth overload due to transportation of data from End nodes to Cloud leading in latency issues, security issues in transporting sensitive medical and financial information across larger gaps in points of data generation and computing, as well as design features of Edge nodes to store and run AI/ML algorithms for effective rendering.

  • Transcultural Artificial Intelligence and Robotics in Health and Social Care

    • 1st Edition
    • Irena Papadopoulos + 3 more
    • English
    Transcultural Artificial Intelligence and Robotics in Health and Social Care provides healthcare professionals with a deeper understanding of the incredible opportunities brought by the emerging field of AI robotics. In addition, it provides robotic researchers with the point-of-view of healthcare professionals to understand what the healthcare sector – as well as the market – really needs from robotics technology. By doing so, the book fills an important gap between both fields in order to leverage new developments and collaborative work in favor of global patients. The book is aimed at the non-technical reader, especially health and social care professionals, and explains in a simple way the technological principles applied in the development of socially assistive humanoid AI robots (SAHR), the values which guide such developments, the ethics related to them, and research approaches in the field, with a focus on achieving a culturally competent SAHR.

  • Feedback Control for Personalized Medicine

    • 1st Edition
    • Esteban A. Hernandez-Vargas
    • English
    Feedback Control for Personalized Medicine provides ideas on ongoing efforts and obstacles by members of the control engineering community in different biological and medical applications. In addition, the book presents key challenges, insights, tools and theoretical developments that arise from personalized medicine, along with medical concepts that are explained by engineers to help non-experts follow research topics. Several clinical trials have tried to find therapeutic approaches to achieve eradication or at least lifelong, therapy-free, host control of the infection. This has been performed integrating clinical observations, empirical knowledge and information from medical tests to treat patients. As this “trial and error” approach is becoming more challenging and unfeasible by the steep increase in the number of different pieces of information and the complexity of large datasets, a systematic and tractable approach that integrates a variety of biological and medical research data into mathematical models and computational algorithms is crucial to harness knowledge and to develop new therapies towards personalized medicine.

  • Novel AI and Data Science Advancements for Sustainability in the Era of COVID-19

    • 1st Edition
    • Victor Chang + 4 more
    • English
    Novel AI and Data Science Advancements for Sustainability in the Era of COVID-19 discusses how the role of recent technologies applied to health settings can help fight virus outbreaks. Moreover, it provides guidelines on how governments and institutions should prepare and quickly respond to drastic situations using technology to support their communities in order to maintain life and functional as efficiently as possible. The book discusses topics such as AI-driven histopathology analysis for COVID-19 diagnosis, bioinformatics for subtype rational drug design, deep learning-based treatment evaluation and outcome prediction, sensor informatics for monitoring infected patients, and machine learning for tracking and prediction models. In addition, the book presents AI solutions for hospital management during an epidemic or pandemic, along with real-world solutions and case studies of successful measures to support different types of communities. This is a valuable source for medical informaticians, bioinformaticians, clinicians and other healthcare workers and researchers who are interested in learning more on how recently developed technologies can help us fight and minimize the effects of global pandemics.

  • Biotechnology in Healthcare, Volume 1

    Technologies and Innovations
    • 1st Edition
    • Debmalya Barh
    • English
    Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare.

  • Digital Innovation for Healthcare in COVID-19 Pandemic: Strategies and Solutions

    • 1st Edition
    • Patricia Ordonez de Pablos + 2 more
    • English
    Approx.428 pages

  • Immunotherapeutics

    • 1st Edition
    • Volume 129
    • Rossen Donev
    • English
    Immunotherapeutics, Volume 129 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Vaccines for the prophylaxis and treatment of HPV, Lung-targeted RNA-based therapeutics, Clostridium difficile: Current overview and future perspectives, Antivenoms for treatment of snake bites, Natural killer cell-based strategies for immunotherapy of cancer, Immunological insights of selectins in human disease mechanism, Current update, challenges, and future aspects of immunotherapeutics in non-small cell lung cancer, In silico interaction analysis of NEMO binding domain peptide on the NFkB protein, and much more.

  • Contemporary Medical Biotechnology Research for Human Health

    • 1st Edition
    • Sanket Joshi + 2 more
    • English
    Contemporary Medical Biotechnology Research for Human Health discusses a range of currently available solutions required to defeat the ever-increasing human health challenges. The junction between biotechnology and biomedical/health sciences has led to several improvements in patients’ treatment, diagnosis and well-being. The book discusses vital topics ranging from biofilms and UTI, mycobacterial infections, diabetes, aplastic anemia, oral cancer, and possible applications of nanoparticles. In addition, it discusses computer-aided drug design using natural products and new technologies to develop antibiotics. This is a valuable resource for biotechnology and biomedical researchers, bioinformaticians and members of health sciences interested in understanding recent technological developments.

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