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Elsevier

Books in Biotechnology

Exploring genetic engineering, cell culture, and bioprocessing, this collection supports researchers and industry professionals developing new therapies, diagnostics, and sustainable bio products. It features innovative techniques, case studies, and regulatory considerations, enabling advancements in healthcare, agriculture, and environmental solutions within a rapidly evolving biotech landscape.

  • Motion Control of Soft Robots

    • 1st Edition
    • Wenyu Liang + 3 more
    • English
    Motion Control of Soft Robots provides an overview of the general concepts and most recent technological updates in soft robot motion control. The book provides systematic coverage of theoretical and practical aspects in system modeling and motion control strategies, presenting novel ideas, methods, and future outlook related to motion control of soft actuators and robots, including model-based control, model-free control, and bioinspired control. This book is useful for researchers, engineers, and students of robotics who can expect to learn how to design and implement various techniques to obtain solutions to control problems in soft robot control and nonlinear system control.

  • Computational Biomechanics of Human Joints

    • 1st Edition
    • Abdelwahed Barkaoui + 2 more
    • English
    Computational Biomechanics of Human Joints delves into the intricate details of each joint, exploring anatomical, mechanical, pathological, and therapeutic aspects. The book offers a comprehensive understanding of joint biomechanics by dedicating each chapter to specific joints, detailing their anatomical structure, biomechanical mechanisms, associated diseases, and pathologies. It also covers treatments, surgical interventions, and imaging-based modeling alongside numerical simulation techniques using the finite element method. This approach provides readers with an innovative perspective on the technological advancements in joint biomechanics. In addition to exploring joint-specific details, the book discusses the advantages and limitations of modern techniques.Finally, the book emphasizes the potential for these methods to improve clinical decision-making, optimize personalized treatments, and design medical devices. The integration of advanced modeling and simulation techniques enhances the understanding of the complex mechanisms of joints, contributing significantly to both academic research and practical clinical applications.

  • Artificial Intelligence Innovations for Biomedical Engineering and Healthcare

    • 1st Edition
    • Alma Y Alanis + 3 more
    • English
    Artificial Intelligence Innovations for Biomedical Engineering and Healthcare bridges the evolving domains of artificial intelligence and biomedical engineering and healthcare. In an era where data-driven insights and precision medicine are essential in healthcare, this book explores emerging trends and showcases AI's potential in transforming patient care, diagnosis, and the treatment of chronic diseases. It simplifies the relationship between artificial intelligence and biomedical engineering, elucidating how these technologies are revolutionizing self-care. The book goes on to examine how advanced technologies, including complex networks and AI-driven diagnostics are reshaping the healthcare landscape.From decoding complex networks to revealing AI's role in treating chronic diseases, this book serves as a guide to understanding how innovation is reshaping the healthcare landscape.

  • Additive Manufacturing Solutions for Advanced Veterinary Practice

    Clinical Dentistry, Orthopedic, and Drug Delivery Methods
    • 1st Edition
    • Rupinder Singh + 2 more
    • English
    Additive Manufacturing Solutions for Advanced Veterinary Practices: Clinical Dentistry, Orthopedic, and Drug Delivery Methods highlights cost- and time-saving 3D printing methods and materials for application on a broad array of veterinary patients and procedures. Additive manufacturing of sensors, biodegradable dental implants, smart dental implants, joint implants, and drug-delivery materials are each covered, as are biomimetic, augmented reality, and virtual reality approaches. Varied additive manufacturing processes and techniques are covered, with each chapter including at least one case study that shows the material covered being put into practical use.

  • Advances in 3D and 4D Printing of Medical Robots and Devices

    • 1st Edition
    • Ankit Sharma + 1 more
    • English
    Advances in 3D and 4D Printing of Medical Robots and Devices presents the most recent innovative breakthroughs in smart manufacturing and biomedical engineering to help enhance knowledge and expertise in 3D/4D printing technologies and advancements in biomedical applications through robotics and medical devices. This book highlights the usage and importance of 3D/4D printing-based prototyping as well as the manufacturing of robotic elements such as energy generators, morphology control, and novel design strategies. This book will help readers to pursue contemporary insights into currently ongoing practices in biomedical and mechatronic engineering including the fabrication of actuators manufacturing; muscles, vibration dampers, bio-inspired structures, pre-surgical and post-surgical tooling, medical assistance robots, drug delivery, microfluidic, and wearable electronics. Academic scholars, manufacturing scientists, and commercial manufacturers of bio-devices and medical robotics will find this book to be useful in adopting competent biomaterials as well as innovative techniques for applications in biomedical engineering.

  • Emerging Fuzzy Intelligent Systems for Smart Healthcare Management

    Applications of Disc q-Rung Orthopair Fuzzy Sets
    • 1st Edition
    • Shahzaib Ashraf + 3 more
    • English
    Emerging Fuzzy Intelligent Systems for Smart Healthcare Management: Applications of Disc q-Rung Orthopair Fuzzy Sets presents comprehensive methodological frameworks and the latest empirical research findings concerning disc q-rung orthopair fuzzy operators, with a specific focus on their applications in smart technologies for healthcare management. The book solves a crucial problem by offering readers an invaluable opportunity to conduct a comparative analysis, contrasting the proposed methods with their existing knowledge base. Disc q-Rung Orthopair sets, being the generalization of q-Rung Orthopair fuzzy sets, which are, in turn, the generalization of Pythagorean fuzzy sets, extend the capabilities of handling uncertainty beyond conventional fuzzy sets.The authors strive to narrow the knowledge gap by clarifying the practical applications of disc q-rung orthopair fuzzy logic. In addition, it explores an enhanced version of q-Rung Orthopair Fuzzy Sets, specifically focusing on Disc q-Rung Orthopair Fuzzy Sets, introducing various types of operators. These operators play a crucial role in solving decision-making and optimization problems. A notable contribution is the development of a hybrid operator, termed as the Disc q-Rung Orthopair Fuzzy Hybrid Weighted Averaging/Geometric (D-qROFHWA/G) operator.

  • Adenoviral Vectors for Gene Therapy

    • 3rd Edition
    • David T. Curiel + 1 more
    • English
    Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, as platforms for gene therapy and gene editing, as well as for oncology approaches, making them class leading agents in the gene-advanced therapies arena.The fully updated and expanded third edition covers the basic biology of adenoviruses and highlights the potential use of adenoviral vectors for the treatment of disease, including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for veterinary applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine applications, and oncolytic adenoviruses for antitumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

  • Explainable AI in Healthcare Imaging for Medical Diagnoses

    Digital Revolution of Artificial Intelligence
    • 1st Edition
    • Tanzila Saba + 2 more
    • English
    In an era where Artificial Intelligence (AI) is revolutionizing healthcare, Explainable AI in Healthcare Imaging for Precision Medicine addresses the critical need for transparency, trust, and accountability in AI-driven medical technologies. As AI becomes an integral part of clinical decision-making, especially in imaging and precision medicine, the question of how AI reaches its conclusions grows increasingly significant. This book explores how Explainable AI (XAI) is transforming healthcare by making AI systems more interpretable, reliable, and transparent, empowering clinicians and enhancing patient outcomes.Through a comprehensive examination of the latest research, real-world case studies, and expert insights, this book delves into the application of XAI in medical imaging, disease diagnosis, treatment planning, and personalized care. It discusses the technical methodologies behind XAI, the challenges and opportunities of its integration into healthcare, and the ethical and regulatory considerations that will shape the future of AI-assisted medical decisions.Key areas of focus include the role of XAI in improving diagnostic accuracy in fields such as radiology, pathology, and genomics and its potential to enhance collaboration between AI systems, healthcare professionals, and patients. The book also highlights practical applications of XAI in personalized medicine, showing how explainable models help tailor treatments to individual patients, and discusses how XAI can contribute to reducing bias and improving fairness in medical decision-making.Writ... by leading experts in AI, healthcare, and precision medicine, Explain[S3G1] able AI in Healthcare Imaging for Precision Medicine is an essential resource for researchers, clinicians, students, and policymakers. Whether you are looking to stay at the forefront of AI innovations in healthcare or seeking to understand how explainability can build trust in AI systems, this book provides the insights and knowledge needed to navigate the evolving landscape of AI in medicine. It invites readers to explore how XAI can revolutionize healthcare and precision medicine, shaping a future where AI is both powerful and trustworthy.

  • Multifunctional Nanostructured Coatings

    Biomedical, Environmental, and Energy Applications
    • 1st Edition
    • Manviri Rani + 1 more
    • English
    Multifunctional Nanostructured Coatings: Biomedical, Environmental, and Energy Applications offers core and advanced information about various nanomaterials and their synthetic approaches to nanostructured coatings. The book focuses on the application of multifunctional nanostructured coatings (MNCs) in the areas of biomedicine, the environment, and energy, and presents the latest advances in the design, preparation, characterization, and fabrication of MNCs. Techniques covered in the book include chemical deposition (including plasma-assisted deposition) and physical deposition methods such as magnetron sputtering, arc evaporation, electron-beam evaporation, and ion-beam sputtering.In addition, the book also explores the use of multifunctional ZnO/TiO2 nanoarray composite coatings, Ta- and Si-doped multifunctional bioactive nanostructured films, in situ-generated titanium-oxo clusters, and silver nanoparticles. It will be useful for researchers working in the areas of materials science, coating technologies, nanotechnology, sustainability, and environmental engineering.

  • Protein Misfolding in Neurodegenerative Diseases

    • 1st Edition
    • Neha Gogia + 2 more
    • English
    Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

  • Federated Learning for Medical Imaging

    Principles, Algorithms, and Applications
    • 1st Edition
    • Xiaoxiao Li + 2 more
    • English
    Federated Learning for Medical Imaging: Principles, Algorithms, and Applications gives a deep understanding of the technology of federated learning (FL), the architecture of a federated system, and the algorithms for FL. It shows how FL allows multiple medical institutes to collaboratively train and use a precise machine learning (ML) model without sharing private medical data via practical implantation guidance. The book includes real-world case studies and applications of FL, demonstrating how this technology can be used to solve complex problems in medical imaging. The book also provides an understanding of the challenges and limitations of FL for medical imaging, including issues related to data and device heterogeneity, privacy concerns, synchronization and communication, etc.This book is a complete resource for computer scientists and engineers, as well as clinicians and medical care policy makers, wanting to learn about the application of federated learning to medical imaging.

  • Necrobotics for Healthcare Applications and Management

    • 1st Edition
    • Hemachandran Kannan + 4 more
    • English
    Necrobotics for Healthcare Applications and Management delves into the emerging area of necrobotics and its implications for healthcare. Exploring the convergence of robotics, technology, and healthcare, the book presents leading-edge research, practical implementations, and ethical considerations. It bridges a significant gap in healthcare literature, furnishing a contemporary and comprehensive perspective on necrobotics. Highlighting its distinct applications, management nuances, and ethical dimensions in the domain of medical robotics, the book equips readers with an in-depth grasp of this evolving field. It offers insights into technological intricacies, practical utilization, and ethical guidelines. Through real-world case studies and exemplar practices, it vividly demonstrates successful necrobotics deployments while addressing integration challenges. The book facilitates adept navigation of necrobotics complexities, spur innovation, enhance patient outcomes, and contribute to healthcare evolution. Catering to the distinct information requisites and daily obstacles encountered by engineers, healthcare practitioners, and researchers, the book offers extensive insights into necrobotics technologies, real-life case studies, and ethical reflections. It stands as a valuable resource for individuals striving to harness necrobotics' potential for efficacious healthcare solutions.

  • Materials and Components of Biosensors in Healthcare

    Volume 2
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Materials and Components of Biosensors in Healthcare: Volume Two provides comprehensive coverage and a detailed examination of the various materials and components used in the development of biosensors. The book begins with an introduction and then discusses the biochemical, inorganic, and biopolymeric components used in biosensor assembly. It goes on to detail a range of materials such as nanoparticles, biological cellular structures, electrochemical, and electromagnetic materials and how they are used in biosensors.Combined with Fundamentals of Biosensors in Healthcare, Volume One, and Applications of Biosensors in Healthcare, Volume Three, this trio provides holistic reference sources suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Applications of Biosensors in Healthcare

    Volume 3
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Applications of Biosensors in Healthcare: Volume 3 details and explores the various ways biosensors are used in healthcare, disease management, and therapeutic delivery.This is the third volume out of three volumes covering biosensors in healthcare. The volume discusses various types of biosensors and their use in diagnostics, health monitoring, disease detection, and therapeutic delivery. Combined with the Volume 1, Fundamentals of Biosensors in Healthcare, and Volume 2, Applications of Biosensors in Healthcare, the volumes provide a holistic reference source suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Gait, Balance, and Mobility Analysis

    Theoretical, Technical, and Clinical Applications
    • 1st Edition
    • Samuel Stuart + 1 more
    • English
    Gait, Balance, and Mobility Analysis: Theoretical, Technical, and Clinical Applications provides a comprehensive overview of gait and movement analysis techniques, from traditional motion capture to modern wearable technologies. The book contains both a technical element that focuses on biomechanics and engineering concepts for gait analysis and the application of gait analysis with clinical populations. Beginning with a comprehensive background on the underlying neural control of gait and mobility in humans and physiological control of balance, the book then covers analysis methods and techniques for laboratory, clinic or remote patient assessment.It then examines how gait, mobility and balance are impacted by musculoskeletal, neurological, and cardio-respiratory conditions. Lastly, it discusses future directions and provides recommendations for future studies. Combining the expertise of engineers and clinicians, this book takes a multidisciplinary approach to show how and why gait, balance and mobility can be used to tackle important clinical questions for various conditions.

  • Lanthanides in Enzymology and Microbiology

    • 1st Edition
    • Akio Tani + 2 more
    • English
    Lanthanides in Enzymology and Microbiology, a new volume in the Foundations and Frontiers in Enzymology Series, offers a detailed discussion of lanthanides and lanthanide-dependent enzyme biology. In this book, more than a dozen global experts consider lanthanide enzymology fundamentals, organismal utilization of lanthanides, distribution and diversity of lanthanide-dependent enzymes, regulation of intracellular levels of lanthanides, gene expression regulation via lanthanides, as well as likely applications of lanthanide binding proteins. Lanthanide-dependent methanol and alcohol dehydrogenase metabolism are considered in both methylotrophs and non-methylotrophs, alongside various application areas, from recovery of rare earth elements to developing lanthanide ion binding peptides and biosynthesis of terpolymers through reverse-oxidation pathways. In providing this deep context and pathways for future research, this book acts as an invaluable resource in this emerging field for researchers and students of biochemistry, biotechnology, and environmental microbiology alike.

  • Trustworthy AI in Medical Imaging

    • 1st Edition
    • Marco Lorenzi + 1 more
    • English
    Trustworthy AI in Medical Imaging brings together scientific researchers, medical experts, and industry partners working in the field of trustworthiness, bridging the gap between AI research and concrete medical applications and making it a learning resource for undergraduates, masters students, and researchers in AI for medical imaging applications.The book will help readers acquire the basic notions of AI trustworthiness and understand its concrete application in medical imaging, identify pain points and solutions to enhance trustworthiness in medical imaging applications, understand current limitations and perspectives of trustworthy AI in medical imaging, and identify novel research directions.Although the problem of trustworthiness in AI is actively researched in different disciplines, the adoption and implementation of trustworthy AI principles in real-world scenarios is still at its infancy. This is particularly true in medical imaging where guidelines and standards for trustworthiness are critical for the successful deployment in clinical practice. After setting out the technical and clinical challenges of AI trustworthiness, the book gives a concise overview of the basic concepts before presenting state-of-the-art methods for solving these challenges.

  • Microfluidics-Aided Technologies

    Platforms for Next Generation Biological Applications
    • 1st Edition
    • Dhananjay Bodas + 1 more
    • English
    Microfluidics-Aided Technologies: Platforms for Next Generation Biological Applications aims to provide comprehensive information of microfluidic technologies, their development and biomedical applications. The book opens with an overview of the fundamentals of microfluidics. It is followed by discussions of methods and biomedical applications of microfluidics in diagnostics, prognostics, cell engineering, gene sequencing, cellular analysis, and bioimaging. The book also explores breakthroughs in microfluidics such as 3D bioprinting, organ-on-chip technologies, and regenerative medicine. This book offers researchers an interdisciplinary perspective towards biological problems. It is a resource for advanced undergraduate, graduate students, researchers and industry scientists interested in the emergence of advance techniques and next generation microfluidics-aided technologies for applications in the biomedical and medical research.

  • Improving Health and Nutrition through Functional Foods

    Benefits and Applications
    • 1st Edition
    • Maira Rubi Segura Campos
    • English
    Improving Health and Nutrition through Functional Foods: Benefits and Applications presents functional foods as a therapeutic approach to disease and overall health and well-being. The book covers various functional foods, such as oilseeds, endemic fruits, and vegetables as foods to consider as complementary treatments for disease management. Written for nutrition researchers, food scientists, graduate students and other food science and health professionals, this book will be a welcomed reference for those who wish to better understand the role of bioactive compounds and functional foods in the treatment and prevention of disease.

  • Fundamentals of Biosensors in Healthcare

    Volume 1
    • 1st Edition
    • Md Saquib Hasnain + 2 more
    • English
    Fundamentals of Biosensors in Healthcare: Volume One provides comprehensive coverage on fundamentals while also delving into the diverse types of biosensors used in healthcare. This first of three volumes covers biosensors in healthcare and explains the history, classifications, and fundamentals of biosensing. It presents current research and the development of biosensors, while also exploring and detailing the distinct types of biosensors and their application in healthcare.Combined with Volume Two, Materials and Components of Biosensors in Healthcare and Volume Three, Applications of Biosensors in Healthcare, users will find a holistic set of reference sources that are suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

  • Rehabilitation Robotics and Healthcare Devices

    • 1st Edition
    • Manuel Cardona
    • English
    Rehabilitation Robotics and Healthcare Devices presents cutting-edge topics in rehabilitation robotics and healthcare devices, covering basic concepts and providing readers with enough information to solve various practical problems. The book proves to be an excellent source to study the different emerging paradigms in rehabilitation robotics and healthcare areas, including related technologies such as sensors, wearable devices, internet of medical things, big data, machine learning for eHealth, edible sensors, robots in medicine, and exoskeleton robots for rehabilitation.

  • Nanosensors in Healthcare Diagnostics

    • 1st Edition
    • Abhinay Sharma + 3 more
    • English
    Nanosensors in Healthcare Diagnostics examines the role of nanosensors in clinical microbiology, point-of-care sensing, clinical diagnostics, and therapy.This book addresses the concept of nanosensors and their utilization in healthcare diagnostics, and therapy. It covers the principles and mechanisms involved in nanosensor-based diagnostics platforms. It also discusses various approaches and techniques used in the preparation of nanosensors as well as the biomedical application of nanosensors in clinical diagnostics and their significance in the detection, treatment, and management of diseases. This book is a useful reference for researchers, graduate students, and industry professionals studying nanosensors in biological and medical sciences.

  • IoMT Applications in Healthcare 5.0

    • 1st Edition
    • Bitan Misra + 2 more
    • English
    IoMT Applications in Healthcare 5.0 introduces the concept of Healthcare 5.0, emphasizing the transformative potential of intelligent diagnosis, remote treatment, and smart health management. Sections define IoMT and its multi-tiered architecture, discussing its pivotal role in improving electronic device productivity in healthcare, explore IoMT applications in Healthcare 5.0, discuss remote physical therapy using IoMT in Healthcare 5.0, delve into the security and privacy considerations of IoMT in healthcare, and address how to overcome challenges and future directions in IoMT. The book concludes by summarizing key findings, providing a comprehensive overview of the discussed topics.Written by experts in the field, this is a key text for Biomedical Engineers, Data Scientists, and IoT Developers and specialists who work in the Internet of Medical Things. Graduate students of IoT engineering, biology, biostatistics, biomedical sciences, bioinformatics, health-informatics, and Interdisciplinary sciences will also find this an invaluable resource.

  • Protocols in Biochemistry and Clinical Biochemistry

    • 2nd Edition
    • Buddhi Prakash Jain + 2 more
    • English
    Protocols in Biochemistry and Clinical Biochemistry, second edition, offers clear, applied instruction in fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose, and cholesterol levels, among other diagnostics. Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods, and troubleshooting, all to support a range of study types and clinical diagnostics. This fully revised edition has been expanded and enriched to feature 100 protocols, as well as chapter key term definitions and worked examples. All-new protocols added to this edition include identification of lipids by TLC, lipid per oxidation measurement by thiobarbituric acid assays, determination of serum amylase, catalase activity assay, superoxide dismutase assay, qualitative analysis of plant secondary metabolites, qualitative analysis of photochemicals, quantitative estimation of secondary metabolites, estimation of chlorophyll contents, and starch determination, among others. Each protocol is written to help researchers and clinicians easily reproduce lab methods and ensure accurate test results.

  • Fungal Stress Mechanisms and Responses

    • 1st Edition
    • Volume 129
    • English
    AAM: Fungal Stress Mechanisms and Responses explores the adaptive strategies and biotechnological applications of fungi under stress conditions. This volume features an array of reviews by experts in the field, reviewing different aspects of fungal stress responses. The initial three chapters focus on stress in fungal insect pathogens, while chapters 4–6 address the impact of stressful environmental conditions on fungi used for bioremediation. The last chapter investigates the molecular aspects of copper homeostasis in human fungal pathogens. This volume offers a comprehensive collection of findings that help our understanding of fungal stress responses and their applications in agriculture, medicine, and the environment.

  • Bio Refinery of Wastewater Treatment

    Way to Generate Waste to Value
    • 1st Edition
    • Maulin P. Shah + 1 more
    • English
    Bio Refinery of Wastewater Treatment: Way to Generate Waste to Value focuses on the exploitation of various wastewater treatment technologies and microbial, chemical, and physical processes as tools for simultaneous value generation during treatment, degradation, detoxification, and stabilization of toxic and hazardous contaminants and restoring contaminated sites. The book provides recents advancements in integrative and cost-effective wastewater treatment strategies and stipulates all pros and cons of each strategy.Bio Refinery of Wastewater Treatment: Way to Generate Waste to Value is valuable to researchers and scientists, who are working in the field of effluent treatment plants/biodegradatio... of environmental contaminants for environmental protection and sustainable development.

  • Predictive Analytics using MATLAB(R) for Biomedical Applications

    • 1st Edition
    • L. Ashok Kumar
    • English
    Predictive Analytics using MATLAB(R) for Biomedical Applications is a comprehensive and practical guide for biomedical engineers, data scientists, and researchers on how to use predictive analytics techniques in MATLAB(R) for solving real-world biomedical problems. The book offers a technical overview of various predictive analytics methods and covers the utilization of MATLAB(R) for implementing these techniques. It includes several case studies that demonstrate how predictive analytics can be applied to real-world biomedical problems, such as predicting disease progression, analyzing medical imaging data, and optimizing treatment outcomes.With a plethora of examples and exercises, this book is the ultimate tool for reinforcing one’s knowledge and skills.

  • Planning, Writing and Reviewing Medical Device Clinical and Performance Evaluation Reports (CERs/PERs)

    A Practical Guide for the European Union and Other Countries
    • 1st Edition
    • Joy Frestedt
    • English
    A Practical Guide to Planning, Writing, and Reviewing Medical Device Clinical Evaluation Reports guides readers through clinical data evaluation of medical devices that is in compliance with the EU MDR requirements and other similar regulatory requirements throughout the world. This book brings together knowledge learned as the author constructed hundreds of CERs and taught thousands of learners on how to conduct clinical data evaluations. This book will support training for clinical engineers, clinical evaluation scientists, and experts reviewing medical device CERs, and will help individual writers, teams and companies to develop stronger, more robust CERs.

  • Biomechatronics

    • 2nd Edition
    • Marko B. Popovic
    • English
    Biomechatronics is rapidly becoming one of the most influential and innovative research directions defining the 21st century. The second edition Biomechatronics provides a complete and up-to-date account of this advanced subject at the university textbook level. This new edition introduces two new chapters – Animals Biomechatronics and Plants Biomechatronics – highlighting the importance of the rapidly growing world population and associated challenges with food production. Each chapter is co-authored by top experts led by Professor Marko B. Popovic, researcher and educator at the forefront of advancements in this fascinating field. Starting with an introduction to the historical background of Biomechatronics, this book covers recent breakthroughs in artificial organs and tissues, prosthetic limbs, neural interfaces, orthotic systems, wearable systems for physical augmentation, physical therapy and rehabilitation, robotic surgery, natural and synthetic actuators, sensors, and control systems. A number of practice prompts and solutions are provided at the end of the book. The second edition of Biomechatronics is a result of dedicated work of a team of more than 30 contributors from all across the globe including top researchers and educators in the United States (Popovic, Lamkin-Kennard, Herr, Sinyukov, Troy, Goodworth, Johnson, Kaipa, Onal, Bowers, Djuric, Fischer, Ji, Jovanovic, Luo, Padir, Tetreault), Japan (Tashiro, Iraminda, Ohta, Terasawa), Sweden (Boyraz), Turkey (Arslan, Karabulut, Ortes), Germany (Beckerle and Wiliwacher), New Zealand (Liarokapis), Switzerland (Dobrev), and Serbia (Lazarevic).

  • Self-powered Sensors

    A Path to Wearable Electronics
    • 1st Edition
    • Rajesh Kumar Dhanaraj + 4 more
    • English
    Self-powered Sensors: A Path to Wearable Electronics features recent developments in chemical, photonic, pharmaceutical, microbiological, biomimetic, and bio-inspired approaches for MEMS/NEMS and medicinal self-powered sensors. Unconventional nanomaterial sensors driven by self-sufficient energy are given a contemporary review, with a focus on the categorization of energy sources and comparisons of research involving self-powered solar, piezoresistive, triboelectric, and thermodynamic technologies. This book also focuses on the different techniques, materials, comparisons of fabrication of self-powered sensors as well as thermoelectric self-powered sensors and its implantable applications.

  • Cannabis and Khat in Drug Discovery

    The Discovery Pipeline and the Endocannabinoid System
    • 1st Edition
    • Andrew G. Mtewa + 4 more
    • English
    Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System provides comprehensive coverage of two important psychoactive plants: Khat and Cannabis. Initial research has found that compounds and derivatives from Cannabis and Khat are found to have promising properties that can be used for the discovery, design and development of potential drug leads against various diseases. This book extensively discusses the drug discovery and allied sciences of these compounds in the drug discovery pipeline, including basic research and computer aided modeling in ligand-drug interactions and their interactions with the endocannabinoid system. Categorized into sections including, chemical analyses and bioassays, medicinal chemistry, chemical biology and pharmacology, clinical applications, and policy and regulations, this book covers the methods and protocols involved and will be of interest to students, researchers, policymakers and all those involved in drug discovery research.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 128
    • English
    Advances in Applied Microbiology, Volume 128 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Circuits, Signals, and Systems for Bioengineers

    A MATLAB-Based Introduction
    • 4th Edition
    • John Semmlow
    • English
    Circuits, Signals, and Systems for Bioengineers: A MATLAB-Based Introduction, Fourth Edition, guides the reader through the electrical engineering principles that can be applied to biological systems. It details the basic engineering concepts that underlie biomedical systems, medical devices, biocontrol, and biomedical signal analysis, providing a solid foundation for students in important bioengineering concepts. Fully revised and updated to better meet the needs of instructors and students, the fourth edition expands on concepts introduced in the previous edition through computational methods that allow students to explore operations, such as correlations, convolution, the Fourier transform, and the transfer function. New medical examples and applications are included throughout the text.

  • Overcoming Cancers Resistant to HER-2 Antibodies

    • 1st Edition
    • Volume 2
    • Benjamin Bonavida
    • English
    Overcoming Cancers Resistant to HER-2 Antibodies provides general updated information on the resistance of various human cancers to anti-HER2 therapeutic antibodies. The book also discusses the description of various sensitizing agents that can reverse resistance when used in combination with anti-HER2 antibodies. There have been a lot of reports in which the treatment with anti-HER2 antibodies for various cancers has resulted in clinical responses; however, there have been also subsets of cancer patients who did not respond initially, and several responding patients developed resistance following treatments. Sections cover Lapatinib, Ganetespib, Paclitaxel, Celecoxib, Emantasine, Liposomal Doxorubicin, and Kinase Inhibitors.This book is a valuable source for cancer researchers, oncologists, pharmacologists and different members of the biomedical field interested in fighting cancer resistance to HER-2 antibodies.

  • Human Organs-on-a-Chip Technology

    • 1st Edition
    • P.V. Mohanan
    • English
    Human Organs-on-a-Chip Technology focuses on technology advancement from “organ-on-a-chip”, “multi organs-on-a-chip”, and the newest stage of “human organs-on-a-chip." Chapters investigate the design, simulation studies, device development, and application of microfluidic systems. In addition, they offer expert perspectives on the development of an alternative test system in the biological evaluation of drugs, cosmetics, chemicals, medical devices, and many others. Lastly, the book addresses issues related to the development of microfluidic devices and alternative test systems in biological and biomedical research.

  • Computational and Network Modeling of Neuroimaging Data

    • 1st Edition
    • Kendrick Kay
    • English
    Computational and Network Modeling of Neuroimaging Data provides an authoritative and comprehensive overview of the many diverse modeling approaches that have been fruitfully applied to neuroimaging data. As neuroimaging is witnessing a massive increase in the quality and quantity of data being acquired, this book gives an accessible foundation to the field of computational neuroimaging, suitable for graduate students, academic researchers, and industry practitioners who are interested in adopting or applying model-based approaches in neuroimaging.It is widely recognized that effective interpretation and extraction of information from complex data requires quantitative modeling. However, modeling the brain comes in many diverse forms, with different research communities tackling different brain systems, different spatial and temporal scales, and different aspects of brain structure and function. This book takes a critical step towards synthesizing and integrating across different modeling approaches.

  • Signal Processing Driven Machine Learning Techniques for Cardiovascular Data Processing

    • 1st Edition
    • Rajesh Kumar Tripathy + 1 more
    • English
    Signal Processing Driven Machine Learning Techniques for Cardiovascular Data Processing features recent advances in machine learning coupled with new signal processing-based methods for cardiovascular data analysis. Topics in this book include machine learning methods such as supervised learning, unsupervised learning, semi-supervised learning, and meta-learning combined with different signal processing techniques such as multivariate data analysis, time-frequency analysis, multiscale analysis, and feature extraction techniques for the detection of cardiovascular diseases, heart valve disorders, hypertension, and activity monitoring using ECG, PPG, and PCG signals.In addition, this book also includes the applications of digital signal processing (time-frequency analysis, multiscale decomposition, feature extraction, non-linear analysis, and transform domain methods), machine learning and deep learning (convolutional neural network (CNN), recurrent neural network (RNN), transformer and attention-based models, etc.) techniques for the analysis of cardiac signals. The interpretable machine learning and deep learning models combined with signal processing for cardiovascular data analysis are also covered.

  • Joint Replacement in the Human Body

    • 1st Edition
    • Thomas J Joyce
    • English
    Joint Replacement in the Human Body provides a comprehensive exploration of artificial joint designs. The book's primary focus is to introduce readers to the diverse landscape of artificial joint technologies while offering insights into their historical development. This book is divided into three sections, each addressing specific aspects of joint replacements. The first section delves into artificial joints of the lower limb, including the hip, knee, and ankle. In the subsequent section, the book explores upper limb replacements, covering joints such as the shoulder, elbow, wrist, finger, and thumb.The third section tackles broader themes like biotribology, regulatory aspects of joint replacements, examines noteworthy case studies like metal-on-metal hips, and addresses joint replacements not easily categorized in the previous sections, such as spinal total disc replacements. This book offers a critical assessment of the diverse and evolving design concepts currently in use, ranging from established metal-on-polymer joints to innovative biomimetic solutions. This book is designed to swiftly equip readers with a deep understanding of contemporary joint replacements and the immediate and long-term challenges they present.

  • Magnetic Nanoparticles in Nanomedicine

    • 1st Edition
    • Kai Wu + 1 more
    • English
    Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI).Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.

  • Advances in Artificial Intelligence

    Biomedical Engineering Applications in Signals and Imaging
    • 1st Edition
    • Kunal Pal + 2 more
    • English
    Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of arti­ficial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical ­ eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.

  • Encyclopedia of Sustainable Technologies

    • 2nd Edition
    • Martin Abraham
    • English
    While technological advancement leads to societal benefits in terms of economic growth, it also brings with it challenges in its impact on the environment or human health. Sustainable development seeks a uniform means of comparing the economic benefits with the environmental and health costs associated with the implementation of a new technology.This revised encyclopedia investigates sustainability initiatives across a range of industries, providing insight into future opportunities for technological development. A broad spectrum of human challenges have only become more intense since publication of the first edition. For example, climate change is now observed across the globe as a contributor to large scale weather events, including extreme drought in Australia, intense wildfires in California, and flooding along the great rivers of Africa, North and South America. Land in the Amazon rain forest is destroyed to provide increased cropland, contributing to climate change. Expansion of the use of biomass as a raw material in chemical processing leads to food shortages. In many cases, these challenges have the greatest impact on the poorest nations, and the most polluting manufacturing facilities are located in the poorest communities, demonstrating social justice challenges.Encyclope... of Sustainable Technologies, Four Volume Set provides a comprehensive analysis of the challenges of modern technology, and the innovations that are leading to better use of limited resources and improved resiliency as we learn to adapt to a changing world. Each chapter examines in depth a technological solution to support a specific human need, evaluates it relative to its impacts on the environment and human health, and considers the social justice issues underlying its development.The new edition provides a stronger link between manufacturing and climate change, updates on new technologies for the generation, distribution and storage of energy, new concepts in resiliency and modularity that have changed manufacturing and chemical processes, and emphasizes the trade-offs required to obtain desired products while minimizing environmental impact.

  • Innovation in Anesthesiology

    Technology, Development, and Commercialization Handbook
    • 1st Edition
    • English
    Innovation in Anesthesiology: Technology, Development, and Commercialization Handbook reflects recent trends of industry globalization and value-conscious healthcare. Written by a team of leading anesthesiologists, engineering development professionals, business analysts, commercialization experts, regulatory and reimbursement specialists, and legal authorities, this volume in the Clinical and Medical Innovation series provides a clear process for the identifi cation, invention, and implementation of new solutions in anesthesiology. This is the ideal resource for anesthesiology innovators who desire to deliver patient solutions and applications to their inventions. Featured case studies on innovative products highlighting the stages required are included for reference.The book will lead researchers, clinicians, entrepreneurs, and investors through a clear process for the identification, invention, and implementation of new clinical technology solutions. Expert medical device inventor/entrepreneu... provide case studies on globally innovative products including successes, failures and practical advice. The book will be a key reference for entrepreneurs developing emerging technology in anesthesia, investors funding innovation in anesthesia, life science business leaders seeking to understand market trends in technology development, tech transfer offices determining prioritization of patenting dollars, distributors seeking to understand trends in anesthesia technology, as well as researchers and engineers seeking to understand market development needs and trends.

  • Carbon-Based Nanomaterials in Biosystems

    Biophysical Interface at Lower Dimensions
    • 1st Edition
    • Kunal Biswas + 3 more
    • English
    Carbon-Based Nanomaterials in Biosystems: Biophysical interface at Lower Dimensions provides a thoroughly comprehensive overview of all major aspects of carbon-based nanomaterials, their biophysical response, and biotechnological applications. The book articulates the underlying physics, chemistry, and the basic phenomenon of the broad-range carbon-based nanomaterials (CNMs) with biological systems, particularly the interface analysis. Organized in six sections, it discusses state-of art technological interventions of carbon-based nanomaterials and their application in biomedical sectors in healthcare, food sciences, and technology. The book also highlights the carrying capacity of different CNMs in payload efficiency mechanisms in various biomedical fields. The theranostic efficiency and the safety of various forms of CNMs is assessed. This book will be a helpful resource to those specializing in the areas of nanomedicine, bionanomaterials, and nanotechnology applications.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 126
    • English
    Advances in Applied Microbiology, Volume 126 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Polymeric Membrane Formation by Phase Inversion

    • 1st Edition
    • Naser Tavajohi + 1 more
    • English
    Polymeric Membrane Formation by Phase Inversion analyzes the four main phase inversion techniques. Effective parameters in each technique are covered, along with the methodologies needed to prepare advanced membranes for specific separations in both liquid and gas phases. Roll-to-roll casting, spinning hollow fiber, and electrospinning nanofibers are presented, along with an analysis of the impact of solvent toxicity, membrane production, and the source of raw materials on the environment. The book describes a roadmap for designing different morphological characteristics for preparing specific membranes for special applications, along with the merits and disadvantages of each method. This book provides an easy, comprehensive reference for academic and industry professionals working in membrane engineering.

  • Microbial Biotechnology for Bioenergy

    • 1st Edition
    • Naga Raju Maddela + 5 more
    • English
    Microbial Biotechnology for Bioenergy presents emerging biotechnological and microbiological approaches in bioenergy and their economic, social, and environmental implications.Section 1 of this book includes an overview of bioenergy, global statistics and projections for future bioenergy development, the role of biotechnology and bioprocesses in bioenergy, feedstock sources, challenges, decarbonisation, and emerging innovations and technologies. Section 2 examines biotechnology and microbiology for bioenergy, including chapters on bioconversion of biomass energy and biological residues, utilizing organic waste, the biotechnology of biofuels including bioethanol, biodiesel, and biohydrogen, the sustainability of cellulosic ethanol energy and artificial photosynthesis, Power-to-X and integrating energy storage innovation, and microbial fuel cell sustainability. Finally, Section 3 explores policy and environmental aspects, providing a global perspective and impact projections based on present-day global statistics.Combining fundamentals and cutting-edge data, Microbial Biotechnology for Bioenergy is a valuable reference for biotechnologists, environmental engineers, and microbiologists working in bioenergy.Also included are ideas for new product development and possible improvement of existing products, as are insights into the unique nature of graphene and its types, including morphology and thickness, mechanical properties, electrical conductivity, elastic properties of 2D and 3D structures, and more.

  • Secondary Metabolites and Biotherapeutics

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Secondary Metabolites and Biotherapeutics presents the latest biotechnological advancements in the production of target secondary metabolites for medicinal use, including topics such as transcriptomics, nanotechnology, gene editing tools like CRISPR/CAS, secondary metabolites source and production.  Secondary metabolites derived from plants as a response to stress have always played a vital role in the pharmaceutical industry to produce medicines. However, their limited production in plants have always raised concerns for large-scale production. With the advancement of modern biotechnology, researchers around the globe are now able to engineer plants with specific chemical compositions.This book is a valuable resource to researchers in biotechnology, medical sciences, pharmaceutical biotechnology, pharmacology and plant biology.

  • Transglutaminase

    Fundamentals and Applications
    • 1st Edition
    • Yi Zhang + 1 more
    • English
    Transglutaminase: Fundamentals and Applications, a new volume in the Foundations and Frontiers in Enzymology series, stands as a comprehensive resource on this increasingly important class of enzymes. Following an introduction to the field, international experts discuss basic biology and structure – function relationships of transglutaminases, ongoing fundamental research, and new application areas, including food processing, material synthesis, biomedicine, disease treatment, and biotechnology. Approaches for sourcing transglutaminases from animals, plants, and microorganisms are considered, followed by chapters on applied uses in biomedicine, skin, bone biology, medicine, drug development, tissue engineering, seafood bioprocessing, dairy bioprocessing, synthesis of materials and polymers, and as an immobilization agent.Research protocols are also provided, including research rationale, design, substrates, assays, and microassay steps for studying transglutaminases.

  • Development in Wastewater Treatment Research and Processes

    Advanced Oxidation Processes for Tannery Effluent
    • 1st Edition
    • Maulin P. Shah + 1 more
    • English
    Advanced Oxidation Processes for Tannery Effluent provides a detailed overview of currently applied and tested sewage treatment technologies and the integration of advanced processes to remove trace organic contaminants and micro-organisms. The book discusses the potential of improved biological treatment to produce reusable wastewater, new municipal wastewater disinfection processes, the reduction of bacteria resistant to antibiotics, as well as the effects of advanced oxidation processes on microbial and chemical contaminants. It features membrane bioreactors, moving bed bioreactors, light and solar technology, ozonation and immobilized heterogeneous photocatalysis, and more. In addition, the book discusses issues and standards for water reuse, the state of application of membrane bioreactors, and the treatment of reverse osmosis concentrate for better water use in wastewater treatment. Final sections present the latest developments in the field of drinking water reuse and address various important issues in this context, such as proper public health protection, reliability and monitoring.

  • Artificial Intelligence and Image Processing in Medical Imaging

    • 1st Edition
    • Walid A. Zgallai + 1 more
    • English
    Artificial Intelligence and Image Processing in Medical Imaging deals with the applications of processing medical images with a view of improving the quality of the data in order to facilitate better decision- making. The book covers the basics of medical imaging and the fundamentals of image processing. It explains spatial and frequency domain applications of image processing, introduces image compression techniques and their applications, and covers image segmentation techniques and their applications. The book includes object detection and classification applications and provides an overall background to statistical analysis in biomedical systems. The role of Machine Learning, including Neural Networks, Deep Learning, and the implications of the expansion of artificial intelligence is also covered. With contributions from prominent researchers worldwide, this book provides up-to-date and comprehensive coverage of AI applications in image processing where readers will find the latest information with clear examples and illustrations.

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