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Elsevier

Books in Biochemistry biophysics

This portfolio spans the molecular mechanisms of life, encompassing protein structure, enzyme function, and biophysical techniques. It supports biochemists, biophysicists, and molecular biologists in understanding complex biological processes. Featuring advanced research, experimental methods, and real-world applications, these resources drive innovations in drug development, disease research, and biomolecular engineering, fostering breakthroughs at the intersection of chemistry, physics, and biology.

  • Artificial Intelligence for Multi-omics Analysis Part A

    • 1st Edition
    • Volume 221
    • English
    Artificial Intelligence for Multi-omics Analysis, Part A, Volume 221 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as an Introduction to Artificial Intelligence in Multi-omics Analysis, Multi‐omics application in health and diseases, Artificial Intelligence in Genomics Analysis, Artificial Intelligence in Single-cell and Spatial Transcriptomics Data, Artificial Intelligence in the prediction of 3D chromatin structure and gene regulation, Artificial intelligence in Mass Spectrometry-based Proteomics, Integrating Artificial Intelligence into Metabolomics for Predicting Diseases, and more.Additional chapters cover Artificial Intelligence in Microbial Metagenomics, Artificial Intelligence in Interactomics, Artificial Intelligence Integration in Medical Imaging Data, AI in biomolecular structural data analysis, Artificial intelligence in Cryo-Electron Microscope data, Explainable artificial intelligence for multi-omics data, and Multi-Omics Cancer Stratification: from Statistical to Deep Learning Perspective.

  • Biostatistical Methods and Applications

    Experiment Design, Analysis, and Presenting Findings
    • 1st Edition
    • Jitendra Kumar Chaudhary
    • English
    Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings provides students and researchers with the skills needed to apply biostatistical concepts and implement a wide range of analytical tools. The text is an accessible and intentionally curated resource that instructs readers in designing experiments, considering the results, and presenting statistical findings and views. In twenty-four chapters and additional appendices, the book starts with an introduction to the field of statistics and from there covers experiment design, data coding, and data collection methods. The book also delves into descriptive statistics, probability, statistical distributions, correlations, and regression. Common research techniques such as normality tests, sample size determination, missing data analysis, statistical inference, test of significance, and ANOVA are explained in a clear manner so that readers can successfully understand and apply these methods. Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings thoroughly explores fundamental topics in biostatistics to guide readers in conducting statistical analysis and interpretation by using the step-by-step procedures and diagrams in the book. This book covers current topics which are being used frequently in teaching and research areas, as well as specific statistical techniques including multivariate analysis, binary logistic regression, and non-parametric methods. This valuable first edition provides the necessary tools and conceptual foundations in quantitative reasoning to efficiently extract information from a vast sea of data, and to communicate research findings in order to support hypotheses and give credibility to research methodology and conclusions. With detailed explanations, illustrative examples and diagrams, and beneficial in-text exercises and solutions to support the study of biostatistics, this textbook will prove useful to students, researchers, and scientists who aim to increase their precision around methods and techniques in this field.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 132
    • English
    Advances in Clinical Chemistry, Volume 132 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including MicroRNAs in Cardiovascular Disease, Salivary Biomarkers in Oral Diseases: From Caries to Cancer – Advances, Challenges, and Future Directions, Exercise Biomarkers, Glycoproteomics of Body Fluids and Derived Exosomes in Hepatocellular Carcinoma, Vitamin D in Health and Disease and Potential Shield Against COVID-19, and RNA Biomarkers in Hemorrhagic Stroke.

  • Immunomodulators - Part A

    • 1st Edition
    • Volume 151
    • English
    Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.

  • Growth Hormone and Related Disorders: From Clinics to Diagnosis

    • 1st Edition
    • Volume 131
    • English
    Growth Hormone and Related Disorders: From Clinics to Diagnosis, Volume 131 covers various topics related to growth hormone and its associated disorders when there is a GH excess, including their pathophysiology, clinical presentation and diagnosis. Chapters in this new release include Growth hormone: synthesis and regulation, GH and GnRH-gonadotropin secretion, Co-Secreting Pituitary Adenomas in Acromegaly: Classification, Diagnosis, and Treatment Strategies, Growth hormone and glycemic metabolism, Acromegaly: pathophysiology and etiology, Acromegaly: biochemical diagnosis, Acromegaly and clinical manifestations, and more.Additional sections discuss Gigantism, Acromegaly and genetics, Molecular markers of response to medical therapy in acromegaly, and Acromegaly and histopathology.

  • Cytoskeletal Proteins in Neurodegenerative Diseases

    • 1st Edition
    • Volume 150
    • English
    Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more. Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.

  • Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions

    • 1st Edition
    • Volume 728
    • English
    Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions, Volume 729 provides a broad snapshot of state-of-the-art methods for studying biological lipids and biomembranes. Sections in this new release cover De novo chemoenzymatic construction of lipid membranes, Photoaffinity labeling for cholesterol metabolism, Expression and Characterization of Phospholipase Cb and Ce enzymes, Assembling Retromer-coated membrane tubules for in vitro structure-function studies, Quantitative analysis of S-acylation, Inhibition of palmitoyltransferase... Exploiting protein lipidation to create peptide-based biomaterials, and much more.Additional sections discuss Optogenetic control of lipid-modifying enzyme activity using LOV domain insertions, Chemoproteomics approaches for inhibition of diacylglycerol kinases, Inhibition of sterol transfer protein function, Preparation of K-Ras4B containing synthetic modifications via expressed protein ligation, Regulation of lipin enzymes on membranes, Use of novel synthetic analogues to decipher the interactions of phosphatidic acids species, Analyzing lipid-nuclear receptor interactions, and much more.

  • Handbook of Material Biodegradation, Biodeterioration, and Biostablization

    • 3rd Edition
    • George Wypych + 2 more
    • English
    Handbook of Material Biodegradation, Biodeterioration, and Biostabilization, Third Edition provides extensive information on the microorganisms involved in the biodegradation of materials, along with the biocides which are permitted for use according to the most up-to-date worldwide legislation. The book focuses on protecting materials and products against colonization and subsequent degradation of their properties. Mechanisms of biodegradation and biodeterioration, results of biodeterioration, and methods of biostabilization are covered for a large number of products, making the title relevant for a range of industries and applications, including construction, coatings/paints, medical and pharmaceutical applications, and electronics. It also covers 13 groups of bacteria, 7 groups of fungi, and 4 groups of protozoa involved in biodegradative processes. In addition, the health and safety aspects of biocide application are covered in detail, as well as the personal protection of practitioners who are required to use them. The contents and the most-up-to-date information make this book essential for almost all the fields of applied chemistry.

  • Lipids and Membranes: Dynamics and Interorganelle Lipid Transport

    • 1st Edition
    • Volume 727
    • English
    Lipids and Membranes: Dynamics and Interorganelle Lipid Transport, Volume 728 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the book's chapters include topics such as Assay of phospholipid scrambling, Tracking lipid transport with bifunctional lipids, Tracking interorganelle lipid transport using genetically encoded mass tags, Molecular Dynamics Simulation of Lipid and Ligand Binding in ORD Domains, Imaging lipid droplet-organelle membrane contact sites using fluorogenic complementation, Studying interactions of amphipathic helices with lipid droplets, and more.Additional chapters cover Metabolic labeling of to trace changes in sphingolipid metabolism, Imaging intracellular lipid heterogeneity with fluorogen-activated coincidence sensing, Tagging lipoproteins in mycobacteria, Probes for studying sphingolipid dynamics, Measuring Flipper-TR Lifetime with Multiple Analysis Strategies, Reconstitution approaches to understanding cellular lipid dynamics, Prediction and characterization of the bacterial lipid handling machinery, From Molecular Dynamics to Cryo-EM: Imaging Liposomes in Silico, and much more.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 131
    • English
    Advances in Clinical Chemistry, Volume 131 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Advances in Volatile Organic Compound Biomarker Detection, 2D-DIGE proteomics, Interacting partners of Tau protein in Alzheimer’s disease, Biosensors for Detection of Autoimmune Disease, Small Molecule Biomarkers in Infectious Disease, and Diagnosis and Risk Factors in Pancreatogenic Diabetes. Each chapter is written by an international board of authors.

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