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Elsevier

Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

  • Immunology: The Making of a Modern Science

    The Making of a Modern Science
    • 1st Edition
    • Richard B. Gallagher + 3 more
    • English
    Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity.The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein.Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective.

  • Immunopharmacology of Platelets

    • 1st Edition
    • M. Joseph
    • English
    Platelets have long been the subject of much investigation in the areas of vascular physiology, biochemistry, immunology and physiopathology. Their ability to react to environmental stimuli, to modify their shape and metabolism despite being anuclear, has fascinated scientists.This volume looks specifically at the involvement of blood platelets outside their 'classical' field of application, in the physiopathological mechanics of allergy and inflammation. The coverage includes the role of platelets in bacterial, parasitic and viral diseases and in tumour cell interactions.

  • Glycoproteins I

    • 1st Edition
    • Volume 29
    • J. Montreuil + 2 more
    • English
    Part I covers modern advances in the determination ofglycoprotein structure and in the biosynthesis of mammalian,bacterial, yeast, plant and insect glycoproteins. There are alsotwo chapters on functional aspects (glycoprotein hormones andcollagens).The content of the volume is very comprehensive in that, mostcontributors have focussed on discussing, in depth, the wealthof most recent advances in their field, and referring to previousreviews of older work for background information. This method caneffectively produce a very wide subject coverage in a smallernumber of chapters/volumes.The volume is an importantinformation source for all glycobiologist researchers (seniorinvestigators... post-doctoral fellows and graduate students), andas a good, comprehensive, reference text for scientists working inthe life sciences.

  • Dictionary of Immunology 4E

    • 4th Edition
    • W. John Herbert + 2 more
    • English
    This is the fourth edition of a well-established dictionary of Immunology which has been completely revised and updatedto include key terms arising from new discoveries in the fast-developing fields of molecular and cellular immunology. It also contains brief descriptions of the most commonly used immunological techniques, as well as definitions, useful in clinical immunology, of immunodeficiency states, autoimmune diseases etc. Clear illustrations and tables have been added to illustrate the text where appropriate. The book should be readily understandable by anyone with a background in biology and many of the definitions should be understandable to the general reader, especially as terms are extensively cross-referenced.It should be useful to those attending immunological meeting or reading immunological journals, especially as scientists communicating to specialized audiences rarely define their terms.It will also be invaluable to undergraduate and postgraduate students in biological and medical sciences, since immunological methods, such as use of monoclonal antibodies, are in wide use throughout biology and medicine.

  • Immunopharmacology of Free Radical Species

    • 1st Edition
    • English
    Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

  • Mechanisms and Models in Rheumatoid Arthritis

    • 1st Edition
    • B. Henderson + 2 more
    • English
    Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.

  • Advances in Immunology

    • 1st Edition
    • Volume 58
    • English
    This text should be a useful guide for researchers in immunology, cell and molecular biology and development biology.

  • Advances in Cancer Research

    Foundations in Cancer Research
    • 1st Edition
    • Volume 65
    • English
    Foundations in Cancer Research has been a feature of Advances in Cancer Research since Volume 59 in 1992. Foundations chapters provide reviews of historical and scientific depth in order to explain studies, events, and personalisties that have had a major impact upon the development of cancer research. Key ideas in these studies still inform current research thinking.In Volume 65, the Editors present a marvelous group of seven new Foundations chapters within a single volume. Subsequent volumes will return to the orginal format of one or two Founations chapters in each volume of the Serial.

  • Advances in Immunology

    • 1st Edition
    • Volume 57
    • English

  • Autoimmune Disease Models

    • 1st Edition
    • Irun R. Cohen + 1 more
    • English
    Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.

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